Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | DMpreB |
| GeneSet | REACTOME_TRANSCRIPTION_COUPLED_NER__TC_NER_ |
| Enrichment Score (ES) | -0.8045574 |
| Normalized Enrichment Score (NES) | -1.5786788 |
| Nominal p-value | 0.0020533882 |
| FDR q-value | 0.06594837 |
| FWER p-Value | 0.629 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | POLD1 | 17847 | 1885 | 0.362 | -0.0824 | No | ||
| 2 | POLD3 | 17742 | 2045 | 0.311 | -0.0746 | No | ||
| 3 | LIG1 | 18388 1749 1493 | 3493 | 0.060 | -0.1493 | No | ||
| 4 | RFC1 | 16527 | 4684 | 0.016 | -0.2126 | No | ||
| 5 | POLR2C | 9750 | 5939 | 0.006 | -0.2797 | No | ||
| 6 | ERCC2 | 1549 18363 3812 | 7385 | 0.001 | -0.3574 | No | ||
| 7 | POLE2 | 21053 | 7971 | 0.000 | -0.3889 | No | ||
| 8 | POLR2B | 16817 | 10051 | -0.005 | -0.5005 | No | ||
| 9 | CDK7 | 21365 | 11644 | -0.011 | -0.5856 | No | ||
| 10 | GTF2H1 | 4069 18236 | 13954 | -0.036 | -0.7079 | No | ||
| 11 | PCNA | 9535 | 15028 | -0.077 | -0.7616 | No | ||
| 12 | RPA1 | 20349 | 15458 | -0.115 | -0.7787 | No | ||
| 13 | POLR2A | 5394 | 15732 | -0.152 | -0.7854 | Yes | ||
| 14 | MNAT1 | 9396 2161 | 15837 | -0.169 | -0.7821 | Yes | ||
| 15 | POLR2I | 12839 | 15977 | -0.195 | -0.7793 | Yes | ||
| 16 | RPA2 | 2330 16057 | 16209 | -0.239 | -0.7792 | Yes | ||
| 17 | ERCC5 | 14255 4097 | 16381 | -0.280 | -0.7737 | Yes | ||
| 18 | ERCC3 | 23605 | 16956 | -0.457 | -0.7805 | Yes | ||
| 19 | CCNH | 7322 | 17056 | -0.491 | -0.7600 | Yes | ||
| 20 | POLE | 16755 | 17267 | -0.584 | -0.7406 | Yes | ||
| 21 | POLR2J | 16672 | 17504 | -0.698 | -0.7166 | Yes | ||
| 22 | RPA3 | 12667 | 17600 | -0.761 | -0.6817 | Yes | ||
| 23 | POLR2G | 23753 | 17605 | -0.763 | -0.6418 | Yes | ||
| 24 | RFC3 | 12786 | 17717 | -0.850 | -0.6031 | Yes | ||
| 25 | GTF2H3 | 5551 | 17720 | -0.851 | -0.5584 | Yes | ||
| 26 | ERCC1 | 1235 1045 1646 | 17880 | -0.954 | -0.5168 | Yes | ||
| 27 | ERCC8 | 12982 3255 3187 | 17902 | -0.970 | -0.4669 | Yes | ||
| 28 | GTF2H2 | 6236 | 17906 | -0.975 | -0.4158 | Yes | ||
| 29 | RFC4 | 1735 22627 | 18026 | -1.106 | -0.3640 | Yes | ||
| 30 | POLD2 | 20537 | 18251 | -1.420 | -0.3014 | Yes | ||
| 31 | POLR2H | 10888 | 18300 | -1.513 | -0.2244 | Yes | ||
| 32 | RFC5 | 13005 7791 | 18353 | -1.673 | -0.1392 | Yes | ||
| 33 | POLR2E | 3325 19699 | 18562 | -2.914 | 0.0029 | Yes |
