Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
Upregulated in class | DMpreB |
GeneSet | REACTOME_DIABETES_PATHWAYS |
Enrichment Score (ES) | -0.6561477 |
Normalized Enrichment Score (NES) | -1.6435219 |
Nominal p-value | 0.0 |
FDR q-value | 0.030691365 |
FWER p-Value | 0.185 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | IGFBP4 | 20670 9160 | 472 | 1.501 | 0.0001 | No | ||
2 | PKM2 | 3642 9573 | 769 | 1.030 | 0.0017 | No | ||
3 | DLD | 2097 21090 | 838 | 0.960 | 0.0145 | No | ||
4 | ETFB | 18279 | 1443 | 0.552 | -0.0088 | No | ||
5 | VAMP2 | 20826 | 1445 | 0.551 | 0.0006 | No | ||
6 | IQGAP1 | 6619 | 1553 | 0.499 | 0.0034 | No | ||
7 | RPS25 | 13270 | 1877 | 0.364 | -0.0079 | No | ||
8 | NDUFS5 | 9296 | 2000 | 0.323 | -0.0090 | No | ||
9 | RPL28 | 5392 | 2053 | 0.309 | -0.0065 | No | ||
10 | SRP14 | 9894 | 2110 | 0.291 | -0.0045 | No | ||
11 | RPL11 | 12450 | 2322 | 0.239 | -0.0119 | No | ||
12 | RPL39 | 12496 | 2355 | 0.232 | -0.0096 | No | ||
13 | ETFDH | 15313 | 2361 | 0.231 | -0.0060 | No | ||
14 | OGDH | 9502 1412 | 2481 | 0.204 | -0.0089 | No | ||
15 | UQCRB | 12545 | 2529 | 0.195 | -0.0081 | No | ||
16 | EXOC8 | 4161 | 2552 | 0.190 | -0.0061 | No | ||
17 | RPS28 | 12009 | 2588 | 0.181 | -0.0049 | No | ||
18 | HSPA5 | 9045 | 2621 | 0.173 | -0.0036 | No | ||
19 | RPS4X | 9756 | 2704 | 0.154 | -0.0054 | No | ||
20 | RPL5 | 9746 | 2846 | 0.129 | -0.0109 | No | ||
21 | RPS15A | 6476 | 2869 | 0.125 | -0.0099 | No | ||
22 | NDUFA6 | 12473 | 2933 | 0.114 | -0.0114 | No | ||
23 | RPLP1 | 3010 | 2978 | 0.108 | -0.0119 | No | ||
24 | NFYA | 5172 | 2982 | 0.108 | -0.0102 | No | ||
25 | COX8A | 8777 | 3014 | 0.104 | -0.0101 | No | ||
26 | RPS20 | 7438 | 3110 | 0.094 | -0.0137 | No | ||
27 | RPL37A | 9744 | 3259 | 0.079 | -0.0203 | No | ||
28 | NDUFS4 | 9452 5157 3173 | 3285 | 0.077 | -0.0204 | No | ||
29 | RPS21 | 12356 | 3518 | 0.058 | -0.0319 | No | ||
30 | SSR4 | 24303 5519 | 3542 | 0.056 | -0.0322 | No | ||
31 | F2 | 14524 | 3648 | 0.049 | -0.0371 | No | ||
32 | IGFBP5 | 4899 | 3718 | 0.046 | -0.0400 | No | ||
33 | RPS5 | 18391 | 4016 | 0.032 | -0.0556 | No | ||
34 | RPL18A | 13358 | 4031 | 0.032 | -0.0558 | No | ||
35 | KLF4 | 9230 4962 4963 | 4261 | 0.025 | -0.0678 | No | ||
36 | RPL27 | 9740 | 4294 | 0.024 | -0.0691 | No | ||
37 | UQCRFS1 | 21499 | 4342 | 0.023 | -0.0712 | No | ||
38 | PLA2G7 | 23233 | 4387 | 0.022 | -0.0732 | No | ||
39 | RPS13 | 12633 | 4564 | 0.018 | -0.0825 | No | ||
40 | CHRM3 | 21547 | 4622 | 0.017 | -0.0853 | No | ||
41 | PGK1 | 9557 5244 | 4675 | 0.016 | -0.0878 | No | ||
42 | RPS29 | 9754 | 4881 | 0.013 | -0.0987 | No | ||
43 | SDHA | 12436 | 5746 | 0.007 | -0.1454 | No | ||
44 | LEP | 17505 | 7224 | 0.002 | -0.2254 | No | ||
45 | NKX2-2 | 5176 | 7599 | 0.001 | -0.2456 | No | ||
46 | PRKAR2B | 5288 2107 | 7813 | 0.000 | -0.2572 | No | ||
47 | KIF5B | 4955 2031 | 8124 | -0.000 | -0.2740 | No | ||
48 | SYT5 | 17986 | 8182 | -0.000 | -0.2770 | No | ||
49 | MMP2 | 18525 | 8553 | -0.001 | -0.2971 | No | ||
50 | IGFBP1 | 20948 | 8685 | -0.002 | -0.3041 | No | ||
51 | SRP19 | 2004 12341 | 8903 | -0.002 | -0.3159 | No | ||
52 | IGFALS | 9158 | 9094 | -0.003 | -0.3261 | No | ||
53 | PFKFB1 | 9552 | 9249 | -0.003 | -0.3344 | No | ||
54 | NDUFB4 | 22596 7541 | 9396 | -0.003 | -0.3422 | No | ||
55 | PDX1 | 16621 | 9556 | -0.004 | -0.3508 | No | ||
56 | GCG | 14578 | 9569 | -0.004 | -0.3514 | No | ||
57 | EXOC5 | 8370 | 9856 | -0.005 | -0.3668 | No | ||
58 | NDUFA4 | 9451 | 9982 | -0.005 | -0.3735 | No | ||
59 | SRP54 | 6282 | 10083 | -0.005 | -0.3788 | No | ||
60 | RPL17 | 11429 6653 | 10171 | -0.005 | -0.3834 | No | ||
61 | RAP1A | 8467 | 10259 | -0.006 | -0.3880 | No | ||
62 | RPS3 | 6549 11295 | 10822 | -0.007 | -0.4184 | No | ||
63 | FFAR1 | 10583 | 11481 | -0.010 | -0.4538 | No | ||
64 | CTSL1 | 4574 | 11618 | -0.011 | -0.4610 | No | ||
65 | PRKCA | 20174 | 11674 | -0.011 | -0.4638 | No | ||
66 | RPL18 | 450 5390 | 11686 | -0.011 | -0.4642 | No | ||
67 | ADRA2A | 4355 | 11700 | -0.011 | -0.4648 | No | ||
68 | RPSA | 19270 4984 | 12226 | -0.014 | -0.4930 | No | ||
69 | MBTPS1 | 18730 3809 3770 | 12251 | -0.014 | -0.4940 | No | ||
70 | RPS16 | 9752 | 12339 | -0.015 | -0.4985 | No | ||
71 | ERN1 | 8137 | 12945 | -0.020 | -0.5309 | No | ||
72 | SDHB | 2348 12566 14880 | 13027 | -0.021 | -0.5349 | No | ||
73 | RPL19 | 9736 | 13379 | -0.026 | -0.5535 | No | ||
74 | EIF2S1 | 4658 | 13425 | -0.026 | -0.5555 | No | ||
75 | GLP1R | 23304 | 13435 | -0.026 | -0.5555 | No | ||
76 | SLC2A2 | 15623 1880 1855 | 13576 | -0.029 | -0.5626 | No | ||
77 | PCSK2 | 9537 5231 14824 | 13798 | -0.033 | -0.5740 | No | ||
78 | RPL41 | 12611 | 13922 | -0.035 | -0.5801 | No | ||
79 | KCNJ11 | 17822 | 14135 | -0.040 | -0.5909 | No | ||
80 | KLK3 | 16337 | 14548 | -0.053 | -0.6123 | No | ||
81 | IGFBP6 | 9161 | 14582 | -0.054 | -0.6132 | No | ||
82 | RPL37 | 12502 7421 22521 | 14583 | -0.054 | -0.6123 | No | ||
83 | ABCC8 | 9941 11649 | 14637 | -0.057 | -0.6142 | No | ||
84 | IGF1 | 3352 9156 3409 | 14645 | -0.057 | -0.6136 | No | ||
85 | PFKFB2 | 4116 5242 | 14654 | -0.057 | -0.6130 | No | ||
86 | ATP5B | 19846 | 14718 | -0.060 | -0.6154 | No | ||
87 | RPS14 | 9751 | 14793 | -0.063 | -0.6183 | No | ||
88 | RPS17 | 9753 | 14884 | -0.068 | -0.6220 | No | ||
89 | RPL8 | 22437 | 14981 | -0.074 | -0.6260 | No | ||
90 | COX4I1 | 18444 | 15341 | -0.102 | -0.6437 | No | ||
91 | CPE | 18868 | 15466 | -0.116 | -0.6484 | No | ||
92 | NDUFS8 | 23950 | 15526 | -0.123 | -0.6495 | No | ||
93 | RPS23 | 12352 | 15534 | -0.125 | -0.6477 | No | ||
94 | NDUFB10 | 23084 | 15606 | -0.134 | -0.6493 | No | ||
95 | SRP72 | 16819 | 15631 | -0.137 | -0.6482 | No | ||
96 | ATP5C1 | 8635 | 15682 | -0.144 | -0.6485 | No | ||
97 | NDUFA2 | 9450 | 15685 | -0.144 | -0.6461 | No | ||
98 | SEC11A | 12144 | 15695 | -0.146 | -0.6441 | No | ||
99 | FAU | 8954 | 15812 | -0.164 | -0.6476 | No | ||
100 | NDUFB7 | 12429 | 15831 | -0.168 | -0.6457 | No | ||
101 | UQCRC1 | 10259 | 15952 | -0.190 | -0.6489 | No | ||
102 | COX5B | 4552 | 16048 | -0.208 | -0.6505 | No | ||
103 | CS | 19839 | 16153 | -0.225 | -0.6523 | Yes | ||
104 | RPS3A | 9755 | 16163 | -0.228 | -0.6489 | Yes | ||
105 | DDOST | 16021 | 16193 | -0.234 | -0.6464 | Yes | ||
106 | NDUFC2 | 18183 | 16225 | -0.245 | -0.6439 | Yes | ||
107 | NDUFB8 | 7418 | 16328 | -0.268 | -0.6449 | Yes | ||
108 | ATP5D | 19949 | 16354 | -0.272 | -0.6416 | Yes | ||
109 | NDUFA11 | 12832 | 16359 | -0.273 | -0.6371 | Yes | ||
110 | COX7C | 8776 | 16420 | -0.288 | -0.6354 | Yes | ||
111 | NDUFAB1 | 7667 | 16449 | -0.296 | -0.6319 | Yes | ||
112 | COX6A1 | 8774 4553 | 16536 | -0.320 | -0.6311 | Yes | ||
113 | ATP5J2 | 12186 | 16583 | -0.333 | -0.6279 | Yes | ||
114 | NDUFC1 | 7287 12339 | 16721 | -0.371 | -0.6289 | Yes | ||
115 | TPI1 | 5795 10212 | 16743 | -0.381 | -0.6235 | Yes | ||
116 | NDUFB5 | 12277 | 16767 | -0.389 | -0.6181 | Yes | ||
117 | SEC61G | 9795 | 16815 | -0.402 | -0.6138 | Yes | ||
118 | UQCRC2 | 18102 | 16822 | -0.404 | -0.6072 | Yes | ||
119 | ATP5O | 22539 | 16907 | -0.437 | -0.6042 | Yes | ||
120 | ATP5F1 | 15212 | 16911 | -0.440 | -0.5969 | Yes | ||
121 | RPS2 | 9279 | 16943 | -0.452 | -0.5908 | Yes | ||
122 | COX6B1 | 4283 8479 | 16988 | -0.469 | -0.5851 | Yes | ||
123 | RPLP2 | 7401 | 17021 | -0.478 | -0.5787 | Yes | ||
124 | COX6C | 8775 | 17029 | -0.479 | -0.5709 | Yes | ||
125 | IDH3G | 24132 | 17064 | -0.495 | -0.5642 | Yes | ||
126 | NDUFS7 | 19946 | 17093 | -0.507 | -0.5571 | Yes | ||
127 | RPL6 | 9747 | 17100 | -0.508 | -0.5487 | Yes | ||
128 | PDHA1 | 24020 | 17140 | -0.524 | -0.5418 | Yes | ||
129 | NDUFA7 | 12347 | 17181 | -0.543 | -0.5347 | Yes | ||
130 | NDUFS2 | 4089 13760 | 17217 | -0.557 | -0.5270 | Yes | ||
131 | NDUFA8 | 14605 | 17254 | -0.578 | -0.5191 | Yes | ||
132 | ATP5I | 8637 | 17259 | -0.582 | -0.5093 | Yes | ||
133 | NDUFS3 | 7553 12683 | 17292 | -0.597 | -0.5008 | Yes | ||
134 | ATF4 | 22417 2239 | 17300 | -0.600 | -0.4909 | Yes | ||
135 | NDUFA10 | 7420 | 17313 | -0.605 | -0.4812 | Yes | ||
136 | ATP5E | 14321 | 17331 | -0.611 | -0.4717 | Yes | ||
137 | NDUFB3 | 12362 | 17332 | -0.611 | -0.4612 | Yes | ||
138 | RPS19 | 5398 | 17418 | -0.653 | -0.4546 | Yes | ||
139 | ATP5A1 | 23505 | 17444 | -0.667 | -0.4446 | Yes | ||
140 | COX7B | 7260 | 17497 | -0.695 | -0.4355 | Yes | ||
141 | NDUFA9 | 12288 | 17506 | -0.699 | -0.4240 | Yes | ||
142 | RPL14 | 19267 | 17549 | -0.733 | -0.4137 | Yes | ||
143 | RPL4 | 7499 19411 | 17597 | -0.760 | -0.4032 | Yes | ||
144 | SLC30A7 | 15186 | 17677 | -0.824 | -0.3934 | Yes | ||
145 | MDH2 | 9399 | 17775 | -0.898 | -0.3833 | Yes | ||
146 | SDHD | 19125 | 17790 | -0.909 | -0.3685 | Yes | ||
147 | NDUFV1 | 23953 | 17810 | -0.917 | -0.3538 | Yes | ||
148 | SSR2 | 15549 | 17876 | -0.951 | -0.3410 | Yes | ||
149 | RPS24 | 5399 | 17893 | -0.962 | -0.3254 | Yes | ||
150 | CYCS | 8821 | 17971 | -1.039 | -0.3118 | Yes | ||
151 | ATP5G1 | 8636 | 18017 | -1.094 | -0.2955 | Yes | ||
152 | UQCR | 12382 | 18041 | -1.126 | -0.2775 | Yes | ||
153 | IDH3A | 19447 | 18114 | -1.221 | -0.2605 | Yes | ||
154 | ATP5J | 880 22555 | 18255 | -1.424 | -0.2437 | Yes | ||
155 | SUCLG1 | 17409 1059 | 18388 | -1.776 | -0.2204 | Yes | ||
156 | SEC61B | 12305 7266 | 18415 | -1.874 | -0.1897 | Yes | ||
157 | RPL27A | 11181 6467 18130 | 18477 | -2.186 | -0.1556 | Yes | ||
158 | GNAS | 9025 2963 2752 | 18528 | -2.517 | -0.1152 | Yes | ||
159 | RPL38 | 12562 20606 7475 | 18614 | -7.000 | 0.0001 | Yes |