Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | V$NFAT_Q6 |
Enrichment Score (ES) | -0.68713546 |
Normalized Enrichment Score (NES) | -1.6621231 |
Nominal p-value | 0.0 |
FDR q-value | 0.040559735 |
FWER p-Value | 0.073 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TNFAIP1 | 20333 | 503 | 1.344 | 0.0054 | No | ||
2 | HSD3B7 | 4158 | 895 | 0.897 | 0.0060 | No | ||
3 | CDC2L2 | 15964 2419 | 979 | 0.822 | 0.0214 | No | ||
4 | VAMP8 | 1034 17117 | 1571 | 0.503 | 0.0016 | No | ||
5 | DTX3 | 19607 | 1749 | 0.438 | 0.0027 | No | ||
6 | SFRS1 | 8492 | 2114 | 0.308 | -0.0096 | No | ||
7 | MAST2 | 9423 | 2130 | 0.303 | -0.0030 | No | ||
8 | LGALS1 | 22429 | 2356 | 0.238 | -0.0094 | No | ||
9 | HSPG2 | 4884 16023 | 2413 | 0.224 | -0.0070 | No | ||
10 | MTIF2 | 13354 | 2798 | 0.139 | -0.0245 | No | ||
11 | TRPS1 | 8195 | 2903 | 0.121 | -0.0272 | No | ||
12 | NDRG2 | 21843 | 3028 | 0.103 | -0.0314 | No | ||
13 | FOXP2 | 4312 17523 8523 | 3267 | 0.076 | -0.0424 | No | ||
14 | JDP2 | 21201 | 3280 | 0.075 | -0.0412 | No | ||
15 | INPP5E | 14650 | 3282 | 0.075 | -0.0395 | No | ||
16 | CAPG | 17411 | 3296 | 0.074 | -0.0384 | No | ||
17 | AGTR2 | 24365 | 3340 | 0.071 | -0.0390 | No | ||
18 | USP2 | 19480 3052 3043 | 3517 | 0.059 | -0.0471 | No | ||
19 | FOXP3 | 9804 5426 | 3549 | 0.056 | -0.0474 | No | ||
20 | COL25A1 | 8056 1837 1844 1915 13376 | 3645 | 0.052 | -0.0513 | No | ||
21 | SNX2 | 1974 23554 12585 | 3765 | 0.046 | -0.0566 | No | ||
22 | CFL2 | 2155 21069 | 3769 | 0.046 | -0.0556 | No | ||
23 | IL4 | 9174 | 3933 | 0.040 | -0.0635 | No | ||
24 | RAB6A | 18173 3905 | 3939 | 0.040 | -0.0628 | No | ||
25 | HOXC4 | 4864 | 3955 | 0.039 | -0.0627 | No | ||
26 | TBX4 | 5633 | 4080 | 0.035 | -0.0685 | No | ||
27 | ANKRD17 | 13496 3474 8170 | 4482 | 0.026 | -0.0896 | No | ||
28 | ELF5 | 14936 2913 | 4523 | 0.025 | -0.0912 | No | ||
29 | HOXB3 | 20685 | 4565 | 0.025 | -0.0928 | No | ||
30 | TRIM47 | 10130 | 4583 | 0.024 | -0.0931 | No | ||
31 | PER2 | 3940 13881 | 4652 | 0.023 | -0.0963 | No | ||
32 | FRS3 | 23209 | 4728 | 0.022 | -0.0998 | No | ||
33 | PAK1IP1 | 21660 | 4887 | 0.020 | -0.1078 | No | ||
34 | BNC2 | 15850 | 5416 | 0.015 | -0.1361 | No | ||
35 | PVRL1 | 3006 19482 12211 7192 | 5572 | 0.013 | -0.1442 | No | ||
36 | EDN1 | 21658 | 5581 | 0.013 | -0.1443 | No | ||
37 | PAX3 | 13910 | 5690 | 0.013 | -0.1498 | No | ||
38 | SLC26A7 | 5538 2372 | 5839 | 0.012 | -0.1576 | No | ||
39 | CNTFR | 2515 15906 | 5952 | 0.011 | -0.1634 | No | ||
40 | FJX1 | 4725 | 5969 | 0.011 | -0.1640 | No | ||
41 | RHOA | 8624 4409 4410 | 6499 | 0.009 | -0.1924 | No | ||
42 | CABP2 | 23765 | 6521 | 0.009 | -0.1933 | No | ||
43 | ZIC1 | 19040 | 6535 | 0.008 | -0.1938 | No | ||
44 | PCDH12 | 7005 | 6584 | 0.008 | -0.1962 | No | ||
45 | TLL1 | 10188 | 6644 | 0.008 | -0.1992 | No | ||
46 | PLAC1 | 12079 | 6700 | 0.008 | -0.2020 | No | ||
47 | IFNB1 | 15846 | 6706 | 0.008 | -0.2021 | No | ||
48 | SPINK5 | 23569 | 6761 | 0.008 | -0.2049 | No | ||
49 | NR3C2 | 18562 13798 | 6901 | 0.007 | -0.2122 | No | ||
50 | PTGER1 | 5309 | 6903 | 0.007 | -0.2121 | No | ||
51 | PITX2 | 15424 1878 | 7190 | 0.006 | -0.2275 | No | ||
52 | ZIC4 | 5992 | 7199 | 0.006 | -0.2277 | No | ||
53 | PHOX2B | 16524 | 7272 | 0.006 | -0.2315 | No | ||
54 | UXS1 | 13965 | 7434 | 0.005 | -0.2401 | No | ||
55 | RBMS3 | 18973 | 7457 | 0.005 | -0.2412 | No | ||
56 | SOX5 | 9850 1044 5480 16937 | 7475 | 0.005 | -0.2420 | No | ||
57 | CAPN6 | 24041 | 7554 | 0.005 | -0.2461 | No | ||
58 | SOX21 | 27 10278 2778 | 7618 | 0.005 | -0.2494 | No | ||
59 | FAP | 14577 | 7753 | 0.004 | -0.2565 | No | ||
60 | HOXA2 | 17151 | 8160 | 0.003 | -0.2784 | No | ||
61 | PDGFB | 22199 2311 | 8288 | 0.003 | -0.2852 | No | ||
62 | SOX10 | 22211 | 8392 | 0.003 | -0.2907 | No | ||
63 | IGFBP3 | 4898 | 8399 | 0.003 | -0.2910 | No | ||
64 | GATA4 | 21792 4755 | 8608 | 0.002 | -0.3022 | No | ||
65 | PCDH10 | 5227 9534 1893 | 8692 | 0.002 | -0.3067 | No | ||
66 | GHR | 22336 | 8939 | 0.001 | -0.3200 | No | ||
67 | COL3A1 | 14253 8765 | 9158 | 0.001 | -0.3318 | No | ||
68 | GNAO1 | 4785 3829 | 9360 | 0.000 | -0.3426 | No | ||
69 | TEAD1 | 18121 | 9364 | 0.000 | -0.3428 | No | ||
70 | TIAL1 | 996 5753 | 9368 | 0.000 | -0.3429 | No | ||
71 | CRY1 | 19662 | 9526 | -0.000 | -0.3515 | No | ||
72 | ERG | 1686 8915 | 9637 | -0.000 | -0.3574 | No | ||
73 | DEPDC2 | 14295 | 9655 | -0.000 | -0.3583 | No | ||
74 | NRK | 6559 | 9713 | -0.001 | -0.3614 | No | ||
75 | SLC6A12 | 17299 | 9750 | -0.001 | -0.3633 | No | ||
76 | SNCAIP | 12589 | 9829 | -0.001 | -0.3675 | No | ||
77 | PAK7 | 14417 | 9892 | -0.001 | -0.3709 | No | ||
78 | TEK | 16175 | 10277 | -0.002 | -0.3916 | No | ||
79 | PLOD2 | 19352 | 10435 | -0.002 | -0.4001 | No | ||
80 | WISP1 | 22463 2289 | 10444 | -0.002 | -0.4004 | No | ||
81 | SP3 | 5483 | 11020 | -0.004 | -0.4315 | No | ||
82 | ARHGAP5 | 4412 8625 | 11027 | -0.004 | -0.4317 | No | ||
83 | DLL4 | 7040 | 11060 | -0.004 | -0.4334 | No | ||
84 | POU3F3 | 14261 | 11115 | -0.004 | -0.4362 | No | ||
85 | SOX3 | 24145 | 11230 | -0.004 | -0.4423 | No | ||
86 | MRGPRF | 17995 | 11249 | -0.004 | -0.4431 | No | ||
87 | LENG4 | 12886 23773 | 11255 | -0.005 | -0.4433 | No | ||
88 | DDR2 | 13767 | 11438 | -0.005 | -0.4530 | No | ||
89 | EXOSC9 | 15610 | 11477 | -0.005 | -0.4550 | No | ||
90 | NFATC4 | 22002 | 11663 | -0.006 | -0.4648 | No | ||
91 | MITF | 17349 | 11764 | -0.006 | -0.4701 | No | ||
92 | ADAMTS17 | 598 | 11789 | -0.006 | -0.4713 | No | ||
93 | FOXB1 | 12254 19069 | 11900 | -0.007 | -0.4771 | No | ||
94 | SPARCL1 | 16457 | 12006 | -0.007 | -0.4826 | No | ||
95 | PCBP2 | 9533 | 12234 | -0.008 | -0.4947 | No | ||
96 | TNXB | 1557 8174 878 8175 | 12365 | -0.009 | -0.5015 | No | ||
97 | POU4F2 | 9603 5276 | 12393 | -0.009 | -0.5028 | No | ||
98 | IL2 | 15354 | 12604 | -0.010 | -0.5139 | No | ||
99 | LIF | 956 667 20960 | 12848 | -0.011 | -0.5268 | No | ||
100 | ARHGAP6 | 24207 | 12924 | -0.011 | -0.5306 | No | ||
101 | CREB5 | 10551 | 13229 | -0.013 | -0.5468 | No | ||
102 | TRPM3 | 23904 10357 5927 | 13361 | -0.014 | -0.5535 | No | ||
103 | BMP5 | 19376 | 13474 | -0.015 | -0.5592 | No | ||
104 | NR2F2 | 8619 409 | 13550 | -0.016 | -0.5629 | No | ||
105 | SULF1 | 6285 | 13595 | -0.017 | -0.5649 | No | ||
106 | FLT4 | 20904 1461 | 13670 | -0.017 | -0.5684 | No | ||
107 | COL8A1 | 4548 | 13720 | -0.018 | -0.5707 | No | ||
108 | RNF128 | 24236 2641 | 13816 | -0.019 | -0.5753 | No | ||
109 | COL16A1 | 16066 | 13966 | -0.021 | -0.5829 | No | ||
110 | TACC2 | 18052 2534 2234 2435 2350 | 14040 | -0.022 | -0.5863 | No | ||
111 | MAGED1 | 24108 | 14402 | -0.029 | -0.6052 | No | ||
112 | JARID2 | 9200 | 14501 | -0.031 | -0.6097 | No | ||
113 | SHOX2 | 1802 5432 | 14688 | -0.036 | -0.6189 | No | ||
114 | ELK3 | 4663 94 3388 | 14711 | -0.037 | -0.6192 | No | ||
115 | SGOL1 | 7810 7809 13030 | 14736 | -0.037 | -0.6196 | No | ||
116 | LIMS1 | 8493 4290 | 14750 | -0.038 | -0.6194 | No | ||
117 | HAPLN1 | 21592 | 14916 | -0.044 | -0.6273 | No | ||
118 | MRPL45 | 20680 | 15071 | -0.050 | -0.6344 | No | ||
119 | ESRRB | 21196 | 15091 | -0.051 | -0.6342 | No | ||
120 | P2RY1 | 15581 | 15124 | -0.052 | -0.6347 | No | ||
121 | TNFRSF1A | 1181 10206 | 15227 | -0.057 | -0.6388 | No | ||
122 | IRF1 | 1336 1258 1433 9182 | 15535 | -0.081 | -0.6535 | No | ||
123 | CPNE1 | 11186 | 15562 | -0.083 | -0.6529 | No | ||
124 | MAP4K4 | 11241 | 15578 | -0.084 | -0.6517 | No | ||
125 | GTF2E1 | 22597 | 15628 | -0.088 | -0.6522 | No | ||
126 | ACVR1 | 4334 | 15671 | -0.092 | -0.6522 | No | ||
127 | PDE4D | 10722 6235 | 15749 | -0.102 | -0.6539 | No | ||
128 | TGFB3 | 10161 | 15910 | -0.122 | -0.6596 | No | ||
129 | ANP32E | 15500 | 16301 | -0.206 | -0.6758 | No | ||
130 | PIK3CD | 9563 | 16512 | -0.261 | -0.6808 | Yes | ||
131 | ADRBK1 | 23960 | 16530 | -0.266 | -0.6753 | Yes | ||
132 | GPX1 | 19310 | 16664 | -0.303 | -0.6751 | Yes | ||
133 | RBM14 | 3673 12087 | 16698 | -0.316 | -0.6692 | Yes | ||
134 | TEC | 16514 | 16770 | -0.340 | -0.6648 | Yes | ||
135 | COMMD10 | 23561 | 16948 | -0.411 | -0.6644 | Yes | ||
136 | KIF3C | 9220 4954 | 16968 | -0.422 | -0.6552 | Yes | ||
137 | ARF6 | 21252 | 17016 | -0.438 | -0.6471 | Yes | ||
138 | INPP5F | 18055 3877 | 17148 | -0.487 | -0.6424 | Yes | ||
139 | FBXL20 | 13010 | 17153 | -0.488 | -0.6308 | Yes | ||
140 | GADD45G | 21637 | 17257 | -0.526 | -0.6236 | Yes | ||
141 | EPHA2 | 16006 | 17330 | -0.562 | -0.6138 | Yes | ||
142 | CD84 | 14049 | 17380 | -0.585 | -0.6023 | Yes | ||
143 | GSK3B | 22761 | 17503 | -0.658 | -0.5929 | Yes | ||
144 | BLR1 | 19145 3154 | 17637 | -0.744 | -0.5820 | Yes | ||
145 | HOXB4 | 20686 | 17727 | -0.811 | -0.5672 | Yes | ||
146 | ZHX2 | 11842 | 17804 | -0.872 | -0.5501 | Yes | ||
147 | ETV5 | 22630 | 17811 | -0.879 | -0.5291 | Yes | ||
148 | FOXP1 | 4242 | 17816 | -0.882 | -0.5079 | Yes | ||
149 | ZBTB5 | 15891 | 17827 | -0.888 | -0.4869 | Yes | ||
150 | TCTA | 4167 | 18012 | -1.092 | -0.4703 | Yes | ||
151 | TIGD2 | 17429 | 18017 | -1.097 | -0.4439 | Yes | ||
152 | EMP1 | 17260 | 18061 | -1.160 | -0.4181 | Yes | ||
153 | ORMDL3 | 12386 | 18080 | -1.189 | -0.3902 | Yes | ||
154 | PTOV1 | 13522 | 18125 | -1.246 | -0.3623 | Yes | ||
155 | KLF13 | 17807 | 18261 | -1.498 | -0.3332 | Yes | ||
156 | SSBP3 | 2439 7814 2431 | 18373 | -1.803 | -0.2955 | Yes | ||
157 | IRF4 | 21679 | 18386 | -1.823 | -0.2519 | Yes | ||
158 | TGFB1 | 18332 | 18387 | -1.827 | -0.2075 | Yes | ||
159 | PHF6 | 2648 24340 | 18503 | -2.490 | -0.1533 | Yes | ||
160 | LASP1 | 4986 4985 1248 | 18546 | -2.918 | -0.0847 | Yes | ||
161 | MARCKS | 9331 | 18574 | -3.642 | 0.0023 | Yes |