Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | transDMpreB |
GeneSet | V$E2F1_Q6_01 |
Enrichment Score (ES) | 0.6029071 |
Normalized Enrichment Score (NES) | 1.425545 |
Nominal p-value | 0.006980803 |
FDR q-value | 0.51271576 |
FWER p-Value | 0.996 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CLSPN | 16079 11256 6530 | 94 | 2.627 | 0.0414 | Yes | ||
2 | MCM7 | 9372 3568 | 178 | 2.099 | 0.0740 | Yes | ||
3 | PPRC1 | 23808 | 179 | 2.097 | 0.1111 | Yes | ||
4 | NCL | 5153 13899 | 191 | 2.049 | 0.1467 | Yes | ||
5 | DNMT1 | 19217 | 226 | 1.914 | 0.1788 | Yes | ||
6 | NOLC1 | 7704 | 300 | 1.658 | 0.2041 | Yes | ||
7 | SYNCRIP | 3078 3035 3107 | 496 | 1.355 | 0.2175 | Yes | ||
8 | CDCA7 | 12437 | 536 | 1.297 | 0.2384 | Yes | ||
9 | NASP | 2383 2387 6955 | 545 | 1.283 | 0.2606 | Yes | ||
10 | UNG | 10257 16744 | 556 | 1.255 | 0.2823 | Yes | ||
11 | MSH2 | 23138 | 676 | 1.101 | 0.2953 | Yes | ||
12 | FKBP5 | 23051 | 693 | 1.087 | 0.3137 | Yes | ||
13 | GSPT1 | 9046 | 730 | 1.047 | 0.3302 | Yes | ||
14 | MCM3 | 13991 | 755 | 1.026 | 0.3471 | Yes | ||
15 | CDC25A | 8721 | 763 | 1.018 | 0.3647 | Yes | ||
16 | POLA2 | 23988 | 781 | 1.001 | 0.3815 | Yes | ||
17 | RQCD1 | 12205 | 782 | 0.999 | 0.3992 | Yes | ||
18 | MCM2 | 17074 | 826 | 0.958 | 0.4138 | Yes | ||
19 | ACBD6 | 14089 | 1019 | 0.792 | 0.4174 | Yes | ||
20 | PHF5A | 22194 | 1022 | 0.790 | 0.4313 | Yes | ||
21 | ATP5G2 | 12610 | 1079 | 0.751 | 0.4415 | Yes | ||
22 | POLD3 | 17742 | 1142 | 0.708 | 0.4507 | Yes | ||
23 | GMNN | 21513 | 1145 | 0.706 | 0.4630 | Yes | ||
24 | PRPS1 | 24233 | 1205 | 0.671 | 0.4717 | Yes | ||
25 | PCNA | 9535 | 1278 | 0.629 | 0.4790 | Yes | ||
26 | AP1S1 | 3500 3453 16335 | 1382 | 0.578 | 0.4836 | Yes | ||
27 | HIRA | 4852 9090 | 1386 | 0.577 | 0.4936 | Yes | ||
28 | ACO2 | 8527 | 1389 | 0.575 | 0.5037 | Yes | ||
29 | MRPL40 | 22641 | 1397 | 0.571 | 0.5134 | Yes | ||
30 | INSM1 | 14815 | 1482 | 0.537 | 0.5184 | Yes | ||
31 | RPS19 | 5398 | 1565 | 0.505 | 0.5229 | Yes | ||
32 | ILF3 | 3110 3030 9176 | 1627 | 0.481 | 0.5281 | Yes | ||
33 | EED | 17759 | 1632 | 0.478 | 0.5363 | Yes | ||
34 | E2F3 | 21500 8874 | 1639 | 0.476 | 0.5444 | Yes | ||
35 | NUMA1 | 18167 | 1693 | 0.455 | 0.5496 | Yes | ||
36 | SUMO1 | 5826 3943 10247 | 1708 | 0.452 | 0.5568 | Yes | ||
37 | CDC5L | 7746 7745 7744 | 1766 | 0.431 | 0.5614 | Yes | ||
38 | SUV39H1 | 24194 | 1774 | 0.430 | 0.5686 | Yes | ||
39 | PPP1R8 | 15730 | 1904 | 0.375 | 0.5682 | Yes | ||
40 | HTF9C | 4886 1678 | 1908 | 0.374 | 0.5747 | Yes | ||
41 | SIN3A | 5442 | 2058 | 0.325 | 0.5723 | Yes | ||
42 | TRIM39 | 22994 | 2080 | 0.319 | 0.5769 | Yes | ||
43 | AMD1 | 8583 | 2095 | 0.314 | 0.5816 | Yes | ||
44 | STMN1 | 9261 | 2099 | 0.313 | 0.5870 | Yes | ||
45 | SFRS1 | 8492 | 2114 | 0.308 | 0.5917 | Yes | ||
46 | E2F1 | 14384 | 2208 | 0.278 | 0.5916 | Yes | ||
47 | DNAJC11 | 2486 6068 | 2362 | 0.237 | 0.5875 | Yes | ||
48 | USP37 | 13923 | 2377 | 0.233 | 0.5909 | Yes | ||
49 | BRMS1L | 21268 | 2399 | 0.227 | 0.5937 | Yes | ||
50 | FHOD1 | 18772 | 2406 | 0.226 | 0.5974 | Yes | ||
51 | SFRS2 | 9807 20136 | 2432 | 0.218 | 0.5999 | Yes | ||
52 | SLC25A1 | 22645 | 2447 | 0.212 | 0.6029 | Yes | ||
53 | FANCC | 4712 | 2628 | 0.168 | 0.5961 | No | ||
54 | USP52 | 3397 19841 | 2840 | 0.130 | 0.5870 | No | ||
55 | PTMA | 9657 | 2964 | 0.111 | 0.5823 | No | ||
56 | PRKDC | 9617 22847 | 3163 | 0.086 | 0.5731 | No | ||
57 | ASXL2 | 7957 | 3226 | 0.080 | 0.5712 | No | ||
58 | GATA1 | 24196 | 3343 | 0.071 | 0.5661 | No | ||
59 | USP2 | 19480 3052 3043 | 3517 | 0.059 | 0.5578 | No | ||
60 | WEE1 | 18127 | 3528 | 0.057 | 0.5583 | No | ||
61 | DDB2 | 2721 2878 14525 2661 | 3870 | 0.042 | 0.5405 | No | ||
62 | MAZ | 1327 17623 | 3923 | 0.040 | 0.5384 | No | ||
63 | PAQR4 | 23105 | 4294 | 0.030 | 0.5189 | No | ||
64 | TNFRSF19L | 11498 6727 6726 | 4323 | 0.029 | 0.5179 | No | ||
65 | NCOA6 | 2876 14382 | 4388 | 0.028 | 0.5149 | No | ||
66 | HMGA2 | 4857 9098 3341 3444 | 4489 | 0.026 | 0.5100 | No | ||
67 | CNOT3 | 6112 10565 6113 | 4496 | 0.026 | 0.5101 | No | ||
68 | HR | 3622 9119 | 4612 | 0.024 | 0.5043 | No | ||
69 | FAF1 | 2508 16137 8951 | 4741 | 0.022 | 0.4978 | No | ||
70 | FBXO5 | 19830 | 4790 | 0.021 | 0.4955 | No | ||
71 | RAD51 | 2897 14903 | 5053 | 0.018 | 0.4817 | No | ||
72 | RPL18 | 450 5390 | 5260 | 0.016 | 0.4708 | No | ||
73 | PHF15 | 20467 8050 | 5286 | 0.016 | 0.4697 | No | ||
74 | REPS2 | 24018 | 5580 | 0.013 | 0.4541 | No | ||
75 | SYT6 | 13437 7042 12040 | 5623 | 0.013 | 0.4520 | No | ||
76 | FANCG | 15904 | 5739 | 0.012 | 0.4460 | No | ||
77 | RANBP1 | 9692 5357 | 5795 | 0.012 | 0.4433 | No | ||
78 | YBX2 | 20818 | 5850 | 0.012 | 0.4405 | No | ||
79 | HNRPUL1 | 6118 17923 1608 10577 1345 | 5900 | 0.011 | 0.4381 | No | ||
80 | ATAD2 | 2268 2256 | 6043 | 0.011 | 0.4306 | No | ||
81 | CDC45L | 22642 1752 | 6572 | 0.008 | 0.4021 | No | ||
82 | IPO7 | 6130 | 6752 | 0.008 | 0.3926 | No | ||
83 | STAG1 | 5520 9905 2987 | 7004 | 0.007 | 0.3791 | No | ||
84 | KCNS2 | 4949 2232 | 7008 | 0.007 | 0.3790 | No | ||
85 | MYH10 | 8077 | 7678 | 0.005 | 0.3429 | No | ||
86 | STK35 | 14851 | 7679 | 0.005 | 0.3430 | No | ||
87 | POLE2 | 21053 | 7815 | 0.004 | 0.3357 | No | ||
88 | PCSK1 | 21600 | 8126 | 0.003 | 0.3190 | No | ||
89 | NPAT | 19452 6356 | 8267 | 0.003 | 0.3114 | No | ||
90 | HOXC10 | 22342 | 8431 | 0.003 | 0.3027 | No | ||
91 | PODN | 15811 | 8681 | 0.002 | 0.2892 | No | ||
92 | PCDH10 | 5227 9534 1893 | 8692 | 0.002 | 0.2887 | No | ||
93 | TYRO3 | 5811 | 8858 | 0.002 | 0.2798 | No | ||
94 | ADAMTS2 | 5706 20899 1356 | 8974 | 0.001 | 0.2736 | No | ||
95 | ERBB2IP | 3232 12234 | 9066 | 0.001 | 0.2687 | No | ||
96 | ATM | 2976 19115 | 9162 | 0.001 | 0.2635 | No | ||
97 | HNRPD | 8645 | 9217 | 0.001 | 0.2606 | No | ||
98 | DNAJC9 | 21912 | 9225 | 0.001 | 0.2603 | No | ||
99 | RB1CC1 | 4486 14299 | 9427 | 0.000 | 0.2494 | No | ||
100 | FZD1 | 16923 | 9429 | 0.000 | 0.2493 | No | ||
101 | BMP2 | 14833 | 9956 | -0.001 | 0.2208 | No | ||
102 | IRX3 | 18793 | 9964 | -0.001 | 0.2205 | No | ||
103 | PAX6 | 5223 | 10181 | -0.002 | 0.2088 | No | ||
104 | MTSS1 | 5585 22285 | 10467 | -0.002 | 0.1934 | No | ||
105 | DHH | 4629 | 10519 | -0.003 | 0.1907 | No | ||
106 | TOPBP1 | 10659 | 10535 | -0.003 | 0.1899 | No | ||
107 | CASP2 | 8692 | 11132 | -0.004 | 0.1577 | No | ||
108 | SPHK2 | 1217 1806 12155 | 11207 | -0.004 | 0.1538 | No | ||
109 | CASP8AP2 | 16253 | 11426 | -0.005 | 0.1421 | No | ||
110 | CBX5 | 22108 4485 | 11480 | -0.005 | 0.1393 | No | ||
111 | HCN3 | 4843 1763 | 11506 | -0.005 | 0.1380 | No | ||
112 | GNG4 | 21706 | 11517 | -0.005 | 0.1376 | No | ||
113 | UXT | 5837 10267 | 12291 | -0.008 | 0.0958 | No | ||
114 | EZH2 | 1092 17163 | 12637 | -0.010 | 0.0773 | No | ||
115 | TNF | 23004 | 12661 | -0.010 | 0.0763 | No | ||
116 | TBX6 | 1993 18075 | 12820 | -0.011 | 0.0679 | No | ||
117 | MGAT2 | 21256 | 12849 | -0.011 | 0.0666 | No | ||
118 | ARHGAP6 | 24207 | 12924 | -0.011 | 0.0628 | No | ||
119 | SYNGR4 | 17825 | 13761 | -0.018 | 0.0178 | No | ||
120 | HNRPR | 13196 7909 2500 | 13777 | -0.019 | 0.0173 | No | ||
121 | GPRC5B | 17662 | 14171 | -0.024 | -0.0035 | No | ||
122 | RBL1 | 14373 | 14215 | -0.025 | -0.0054 | No | ||
123 | MCM8 | 14834 | 14573 | -0.033 | -0.0242 | No | ||
124 | KLF5 | 4456 | 14590 | -0.033 | -0.0245 | No | ||
125 | ACTN3 | 23967 8540 | 14766 | -0.038 | -0.0333 | No | ||
126 | ERF | 4680 8914 | 14901 | -0.043 | -0.0398 | No | ||
127 | POU2F1 | 5275 3989 4065 4010 | 14921 | -0.044 | -0.0400 | No | ||
128 | MYC | 22465 9435 | 14956 | -0.045 | -0.0411 | No | ||
129 | SP1 | 9852 | 15014 | -0.048 | -0.0433 | No | ||
130 | SMARCA1 | 24165 | 15209 | -0.057 | -0.0528 | No | ||
131 | EFNA5 | 4655 8884 | 15286 | -0.061 | -0.0559 | No | ||
132 | LRP1 | 9284 | 15413 | -0.071 | -0.0615 | No | ||
133 | JPH1 | 13994 | 15540 | -0.081 | -0.0669 | No | ||
134 | AP4M1 | 3499 16656 | 15591 | -0.085 | -0.0681 | No | ||
135 | MCM6 | 4000 13845 4119 | 15695 | -0.095 | -0.0720 | No | ||
136 | ORC1L | 327 16144 | 15713 | -0.097 | -0.0712 | No | ||
137 | ENPP1 | 19804 | 15742 | -0.101 | -0.0709 | No | ||
138 | PHF13 | 15659 | 15744 | -0.101 | -0.0692 | No | ||
139 | TMPO | 5778 | 16117 | -0.167 | -0.0864 | No | ||
140 | STAG2 | 5521 | 16171 | -0.178 | -0.0861 | No | ||
141 | HMGN2 | 9095 | 16174 | -0.179 | -0.0830 | No | ||
142 | UFD1L | 22825 | 16340 | -0.214 | -0.0882 | No | ||
143 | PIK3CD | 9563 | 16512 | -0.261 | -0.0928 | No | ||
144 | CHD4 | 8418 17281 4225 | 16588 | -0.283 | -0.0919 | No | ||
145 | CTCF | 18490 | 16654 | -0.300 | -0.0901 | No | ||
146 | HIST1H2AH | 11414 | 16657 | -0.302 | -0.0849 | No | ||
147 | MAP4K1 | 18313 | 16669 | -0.306 | -0.0801 | No | ||
148 | GADD45B | 19935 | 16715 | -0.321 | -0.0769 | No | ||
149 | ATE1 | 388 17602 | 16725 | -0.325 | -0.0716 | No | ||
150 | SLC9A7 | 24177 | 16886 | -0.389 | -0.0734 | No | ||
151 | AK2 | 8563 2479 16073 | 16960 | -0.419 | -0.0699 | No | ||
152 | CCNT1 | 22140 11607 | 17006 | -0.435 | -0.0647 | No | ||
153 | MCM4 | 22655 1708 | 17543 | -0.687 | -0.0816 | No | ||
154 | RAB11B | 9676 | 17688 | -0.781 | -0.0756 | No | ||
155 | PPM1D | 20721 | 18030 | -1.116 | -0.0743 | No | ||
156 | MXD3 | 21455 | 18151 | -1.270 | -0.0583 | No | ||
157 | HIST1H2BK | 11423 | 18232 | -1.432 | -0.0373 | No | ||
158 | FLI1 | 4729 | 18239 | -1.444 | -0.0121 | No | ||
159 | HNRPA1 | 9103 4860 | 18392 | -1.837 | 0.0121 | No |