Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | TCRPATHWAY |
| Enrichment Score (ES) | -0.79435116 |
| Normalized Enrichment Score (NES) | -1.6006569 |
| Nominal p-value | 0.0021231424 |
| FDR q-value | 0.13681667 |
| FWER p-Value | 0.283 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTPN7 | 11500 | 1675 | 0.461 | -0.0611 | No | ||
| 2 | MAPK8 | 6459 | 2251 | 0.267 | -0.0752 | No | ||
| 3 | MAP2K1 | 19082 | 2640 | 0.166 | -0.0856 | No | ||
| 4 | CD3D | 19473 | 2923 | 0.118 | -0.0933 | No | ||
| 5 | FOS | 21202 | 4235 | 0.031 | -0.1619 | No | ||
| 6 | SHC1 | 9813 9812 5430 | 4437 | 0.027 | -0.1711 | No | ||
| 7 | HRAS | 4868 | 4722 | 0.022 | -0.1849 | No | ||
| 8 | ZAP70 | 14271 4042 | 6326 | 0.009 | -0.2707 | No | ||
| 9 | CALM1 | 21184 | 6895 | 0.007 | -0.3008 | No | ||
| 10 | CD3G | 19139 | 8314 | 0.003 | -0.3770 | No | ||
| 11 | CD3E | 8714 | 8903 | 0.001 | -0.4085 | No | ||
| 12 | PPP3CA | 1863 5284 | 9030 | 0.001 | -0.4152 | No | ||
| 13 | LAT | 17643 | 9183 | 0.001 | -0.4234 | No | ||
| 14 | SYT1 | 5565 | 9505 | -0.000 | -0.4406 | No | ||
| 15 | PLCG1 | 14753 | 9774 | -0.001 | -0.4550 | No | ||
| 16 | NFATC2 | 5168 2866 | 10619 | -0.003 | -0.5003 | No | ||
| 17 | SOS1 | 5476 | 10751 | -0.003 | -0.5071 | No | ||
| 18 | TRB@ | 1157 | 11555 | -0.005 | -0.5500 | No | ||
| 19 | NFATC4 | 22002 | 11663 | -0.006 | -0.5554 | No | ||
| 20 | PIK3R1 | 3170 | 11690 | -0.006 | -0.5564 | No | ||
| 21 | PIK3CA | 9562 | 13925 | -0.021 | -0.6754 | No | ||
| 22 | FYN | 3375 3395 20052 | 15046 | -0.049 | -0.7326 | No | ||
| 23 | CALM2 | 8681 | 16194 | -0.184 | -0.7827 | Yes | ||
| 24 | RASA1 | 10174 | 16249 | -0.195 | -0.7734 | Yes | ||
| 25 | NFATC3 | 5169 | 16282 | -0.202 | -0.7623 | Yes | ||
| 26 | RAF1 | 17035 | 16474 | -0.248 | -0.7570 | Yes | ||
| 27 | GRB2 | 20149 | 16888 | -0.389 | -0.7546 | Yes | ||
| 28 | CALM3 | 8682 | 16904 | -0.395 | -0.7305 | Yes | ||
| 29 | PPP3CB | 5285 | 16962 | -0.419 | -0.7072 | Yes | ||
| 30 | MAPK3 | 6458 11170 | 17011 | -0.437 | -0.6822 | Yes | ||
| 31 | RAC1 | 16302 | 17052 | -0.451 | -0.6559 | Yes | ||
| 32 | PRKCB1 | 1693 9574 | 17109 | -0.475 | -0.6289 | Yes | ||
| 33 | PPP3CC | 21763 | 17176 | -0.498 | -0.6010 | Yes | ||
| 34 | MAP2K4 | 20405 | 17227 | -0.515 | -0.5711 | Yes | ||
| 35 | PRKCA | 20174 | 17237 | -0.520 | -0.5388 | Yes | ||
| 36 | RELA | 23783 | 17583 | -0.705 | -0.5128 | Yes | ||
| 37 | NFKB1 | 15160 | 17682 | -0.778 | -0.4690 | Yes | ||
| 38 | JUN | 15832 | 17701 | -0.791 | -0.4200 | Yes | ||
| 39 | VAV1 | 23173 | 17823 | -0.886 | -0.3706 | Yes | ||
| 40 | NFKBIA | 21065 | 18048 | -1.142 | -0.3106 | Yes | ||
| 41 | MAP3K1 | 21348 | 18088 | -1.200 | -0.2369 | Yes | ||
| 42 | LCK | 15746 | 18240 | -1.451 | -0.1534 | Yes | ||
| 43 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 18536 | -2.749 | 0.0043 | Yes |
