Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB
Phenotype	phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB
Upregulated in class	transDMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	0.71174264
Normalized Enrichment Score (NES)	1.6629328
Nominal p-value	0.0
FDR q-value	0.016217101
FWER p-Value	0.04

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR1D	3593 3658 16623	18	4.063	0.0541	Yes
2	POLR1B	14857	32	3.400	0.0994	Yes
3	GART	22543 1754	121	2.400	0.1272	Yes
4	ATIC	14231 3968	128	2.362	0.1589	Yes
5	APRT	8620	144	2.254	0.1886	Yes
6	NME4	23065 1577	174	2.127	0.2158	Yes
7	NME2	9468	175	2.112	0.2445	Yes
8	RRM2	5401 5400	222	1.924	0.2680	Yes
9	NME1	9467	229	1.906	0.2935	Yes
10	IMPDH2	10730	230	1.901	0.3193	Yes
11	POLD2	20537	245	1.841	0.3435	Yes
12	ADA	2703 14361	266	1.775	0.3664	Yes
13	PPAT	6081	271	1.764	0.3901	Yes
14	POLE	16755	314	1.622	0.4098	Yes
15	PDE6D	13897 3945	467	1.413	0.4207	Yes
16	GUK1	20432	474	1.395	0.4393	Yes
17	POLR3H	13460 8135	481	1.385	0.4578	Yes
18	ADSL	4358	482	1.385	0.4765	Yes
19	NUDT5	15121	484	1.379	0.4952	Yes
20	RFC5	13005 7791	515	1.327	0.5115	Yes
21	PAICS	16820	552	1.262	0.5267	Yes
22	POLE3	7200	616	1.176	0.5392	Yes
23	NT5M	8345 4175	637	1.153	0.5537	Yes
24	RRM1	18163	645	1.145	0.5689	Yes
25	POLR2H	10888	646	1.144	0.5844	Yes
26	PKM2	3642 9573	675	1.102	0.5978	Yes
27	NME6	3139 19297	724	1.055	0.6095	Yes
28	POLA2	23988	781	1.001	0.6200	Yes
29	ENTPD4	7449	840	0.939	0.6296	Yes
30	NUDT9	7897	873	0.916	0.6403	Yes
31	POLR2E	3325 19699	901	0.891	0.6509	Yes
32	GMPS	15578	996	0.810	0.6568	Yes
33	PRIM1	19847	1125	0.723	0.6597	Yes
34	POLD3	17742	1142	0.708	0.6684	Yes
35	IMPDH1	17197 1131	1169	0.692	0.6763	Yes
36	POLR2J	16672	1186	0.681	0.6847	Yes
37	HPRT1	2655 24339 408	1187	0.681	0.6939	Yes
38	PRPS1	24233	1205	0.671	0.7021	Yes
39	PRPS2	24003	1351	0.594	0.7023	Yes
40	POLR2K	9413	1517	0.524	0.7005	Yes
41	NUDT2	16239	1570	0.503	0.7045	Yes
42	PDE8A	18202	1648	0.471	0.7067	Yes
43	POLR3A	21900	1672	0.462	0.7117	Yes
44	POLR1A	9749 5393	2115	0.308	0.6920	No
45	POLR2I	12839	2516	0.193	0.6730	No
46	ECGF1	22160	2676	0.161	0.6666	No
47	POLR2A	5394	2747	0.149	0.6648	No
48	PNPT1	20936	2830	0.133	0.6622	No
49	NT5E	19360 18702	3274	0.076	0.6392	No
50	PDE10A	23387	3355	0.070	0.6358	No
51	XDH	22897	3482	0.060	0.6298	No
52	ENTPD6	4496 2678	3865	0.043	0.6098	No
53	AK3L1	8564	4194	0.032	0.5925	No
54	AK5	6042	4195	0.032	0.5929	No
55	GUCY1A3	7216 12245 15310	5039	0.018	0.5475	No
56	ADCY4	2980 21818	5328	0.015	0.5322	No
57	AMPD2	1931 15197	5330	0.015	0.5323	No
58	GDA	4764	5670	0.013	0.5142	No
59	ITPA	9193	5993	0.011	0.4969	No
60	ENTPD3	19266	6168	0.010	0.4876	No
61	AMPD1	5051	6248	0.010	0.4835	No
62	ENTPD8	12996	6288	0.009	0.4815	No
63	PDE2A	18170	6392	0.009	0.4760	No
64	POLR3K	12447 7372	6896	0.007	0.4489	No
65	RRM2B	6902 6903 11801	6930	0.007	0.4472	No
66	PDE6G	20119	7120	0.006	0.4371	No
67	PDE5A	15431	7151	0.006	0.4356	No
68	ADCY8	22281	7339	0.006	0.4255	No
69	GUCY2F	24045	7454	0.005	0.4194	No
70	PAPSS2	6258	7461	0.005	0.4192	No
71	GUCY1A2	19580	7613	0.005	0.4111	No
72	POLE2	21053	7815	0.004	0.4003	No
73	ALLC	21093 2130	7948	0.004	0.3932	No
74	POLR2C	9750	8110	0.003	0.3845	No
75	ENTPD1	4495	8187	0.003	0.3804	No
76	NPR1	9480	8679	0.002	0.3539	No
77	PDE1A	9541 5234	8950	0.001	0.3393	No
78	POLA1	24112	9653	-0.000	0.3014	No
79	NP	22027 9597 5273 5274	9773	-0.001	0.2949	No
80	ADCY3	21329 894	9899	-0.001	0.2882	No
81	NPR2	16230	10933	-0.004	0.2324	No
82	GUCY2C	1140 16954	11013	-0.004	0.2281	No
83	CANT1	13304	11171	-0.004	0.2197	No
84	ADK	3302 3454 8555	11260	-0.005	0.2150	No
85	PKLR	1850 15545	11427	-0.005	0.2061	No
86	ENPP3	19803	11641	-0.006	0.1947	No
87	POLR3B	12875	11695	-0.006	0.1919	No
88	ENTPD2	8713	11872	-0.007	0.1824	No
89	POLR2B	16817	12059	-0.007	0.1725	No
90	AK1	4363	12126	-0.007	0.1690	No
91	PDE8B	5756	12164	-0.008	0.1671	No
92	ADCY5	10312	12491	-0.009	0.1496	No
93	PDE9A	23301	12652	-0.010	0.1411	No
94	PDE1C	5235	12671	-0.010	0.1403	No
95	PDE6H	17257	13103	-0.013	0.1171	No
96	GUCY1B3	15311	13349	-0.014	0.1041	No
97	PDE11A	10805	13519	-0.016	0.0951	No
98	PDE4A	3037 19542 3083 3023	13615	-0.017	0.0902	No
99	PDE7B	19807	13687	-0.018	0.0866	No
100	ADCY6	22139 2283 8551	13729	-0.018	0.0846	No
101	AMPD3	4383 2110	13800	-0.019	0.0811	No
102	NME7	926 4101 14070 3986 3946 931	13857	-0.020	0.0784	No
103	ADCY2	21412	14014	-0.022	0.0702	No
104	NT5C1B	21315	14053	-0.022	0.0685	No
105	PDE3B	5236	14827	-0.040	0.0272	No
106	PDE4C	8481	15624	-0.088	-0.0147	No
107	ENPP1	19804	15742	-0.101	-0.0196	No
108	PDE4D	10722 6235	15749	-0.102	-0.0186	No
109	GMPR2	2711	15809	-0.107	-0.0203	No
110	PDE4B	9543	16079	-0.158	-0.0327	No
111	POLR2G	23753	16110	-0.165	-0.0321	No
112	NT5C3	17136	16113	-0.167	-0.0300	No
113	ADCY9	22680	16230	-0.191	-0.0337	No
114	ADCY7	8552 448	16369	-0.222	-0.0381	No
115	NT5C	20151	16435	-0.236	-0.0384	No
116	GMPR	21651	16520	-0.264	-0.0394	No
117	PAPSS1	15419	16824	-0.362	-0.0509	No
118	POLD1	17847	16839	-0.368	-0.0466	No
119	AK2	8563 2479 16073	16960	-0.419	-0.0475	No
120	DGUOK	17099 1041	17097	-0.468	-0.0485	No
121	POLE4	12441	17279	-0.536	-0.0510	No
122	NT5C2	3768 8052	17383	-0.587	-0.0486	No
123	ENTPD5	4497	17497	-0.654	-0.0459	No
124	FHIT	21920	17514	-0.663	-0.0378	No
125	ZNRD1	1491 22987	17560	-0.693	-0.0308	No
126	PDE7A	9544 1788	17646	-0.750	-0.0252	No
127	DCK	16808	17984	-1.054	-0.0292	No
128	POLD4	12822	18404	-1.867	-0.0266	No
129	ADSSL1	21136 2087	18542	-2.803	0.0040	No