Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | transDMpreB |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | 0.693045 |
| Normalized Enrichment Score (NES) | 1.397248 |
| Nominal p-value | 0.058287796 |
| FDR q-value | 0.5904123 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MCM7 | 9372 3568 | 178 | 2.099 | 0.0592 | Yes | ||
| 2 | POLD2 | 20537 | 245 | 1.841 | 0.1159 | Yes | ||
| 3 | RFC1 | 16527 | 282 | 1.712 | 0.1701 | Yes | ||
| 4 | NACA | 9444 5147 | 295 | 1.668 | 0.2241 | Yes | ||
| 5 | POLE | 16755 | 314 | 1.622 | 0.2762 | Yes | ||
| 6 | RFC5 | 13005 7791 | 515 | 1.327 | 0.3089 | Yes | ||
| 7 | RFC4 | 1735 22627 | 560 | 1.250 | 0.3475 | Yes | ||
| 8 | ORC6L | 18539 | 562 | 1.247 | 0.3883 | Yes | ||
| 9 | MCM10 | 14694 | 607 | 1.183 | 0.4247 | Yes | ||
| 10 | MCM3 | 13991 | 755 | 1.026 | 0.4504 | Yes | ||
| 11 | POLA2 | 23988 | 781 | 1.001 | 0.4818 | Yes | ||
| 12 | MCM2 | 17074 | 826 | 0.958 | 0.5109 | Yes | ||
| 13 | RPA1 | 20349 | 1036 | 0.778 | 0.5251 | Yes | ||
| 14 | PRIM1 | 19847 | 1125 | 0.723 | 0.5440 | Yes | ||
| 15 | POLD3 | 17742 | 1142 | 0.708 | 0.5664 | Yes | ||
| 16 | GMNN | 21513 | 1145 | 0.706 | 0.5894 | Yes | ||
| 17 | PRIM2A | 13986 | 1226 | 0.659 | 0.6067 | Yes | ||
| 18 | MCM5 | 18564 | 1236 | 0.655 | 0.6276 | Yes | ||
| 19 | PCNA | 9535 | 1278 | 0.629 | 0.6460 | Yes | ||
| 20 | RPA2 | 2330 16057 | 1299 | 0.622 | 0.6653 | Yes | ||
| 21 | RPA3 | 12667 | 1341 | 0.601 | 0.6828 | Yes | ||
| 22 | CDT1 | 18437 | 1479 | 0.538 | 0.6930 | Yes | ||
| 23 | CDK2 | 3438 3373 19592 3322 | 1795 | 0.415 | 0.6897 | No | ||
| 24 | ORC5L | 11173 3595 | 2023 | 0.336 | 0.6885 | No | ||
| 25 | RFC3 | 12786 | 2294 | 0.254 | 0.6823 | No | ||
| 26 | CDC6 | 6221 6220 | 4092 | 0.035 | 0.5867 | No | ||
| 27 | ORC4L | 11172 6460 | 4586 | 0.024 | 0.5609 | No | ||
| 28 | UBB | 10240 | 6109 | 0.010 | 0.4793 | No | ||
| 29 | CDC45L | 22642 1752 | 6572 | 0.008 | 0.4547 | No | ||
| 30 | POLE2 | 21053 | 7815 | 0.004 | 0.3880 | No | ||
| 31 | UBC | 14 14 10241 15 16 | 14039 | -0.022 | 0.0537 | No | ||
| 32 | UBA52 | 10239 | 14193 | -0.025 | 0.0463 | No | ||
| 33 | ORC2L | 385 13949 | 15052 | -0.049 | 0.0017 | No | ||
| 34 | RPS27A | 13433 | 15211 | -0.057 | -0.0049 | No | ||
| 35 | ORC3L | 6941 | 15682 | -0.094 | -0.0271 | No | ||
| 36 | MCM6 | 4000 13845 4119 | 15695 | -0.095 | -0.0247 | No | ||
| 37 | ORC1L | 327 16144 | 15713 | -0.097 | -0.0224 | No | ||
| 38 | POLD1 | 17847 | 16839 | -0.368 | -0.0709 | No | ||
| 39 | MCM4 | 22655 1708 | 17543 | -0.687 | -0.0863 | No | ||
| 40 | POLD4 | 12822 | 18404 | -1.867 | -0.0714 | No | ||
| 41 | CDC7 | 16765 3477 | 18513 | -2.527 | 0.0055 | No |
