Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | NETPATH_BCR |
Enrichment Score (ES) | -0.66222274 |
Normalized Enrichment Score (NES) | -1.5589744 |
Nominal p-value | 0.0 |
FDR q-value | 0.10742878 |
FWER p-Value | 0.742 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTK2 | 22271 | 31 | 3.407 | 0.0461 | No | ||
2 | DOK3 | 3229 21451 | 39 | 3.268 | 0.0916 | No | ||
3 | CCNE1 | 17857 | 444 | 1.453 | 0.0901 | No | ||
4 | BLNK | 23681 3691 | 685 | 1.092 | 0.0924 | No | ||
5 | CYCS | 8821 | 1112 | 0.728 | 0.0796 | No | ||
6 | MAP3K7 | 16255 | 1281 | 0.628 | 0.0794 | No | ||
7 | BAX | 17832 | 1302 | 0.620 | 0.0870 | No | ||
8 | RPS6 | 9757 | 1335 | 0.604 | 0.0937 | No | ||
9 | IKBKB | 4907 | 1740 | 0.441 | 0.0781 | No | ||
10 | CDK2 | 3438 3373 19592 3322 | 1795 | 0.415 | 0.0810 | No | ||
11 | CHUK | 23665 | 1827 | 0.403 | 0.0850 | No | ||
12 | MAPK8 | 6459 | 2251 | 0.267 | 0.0658 | No | ||
13 | RPS6KA1 | 15725 | 2384 | 0.231 | 0.0619 | No | ||
14 | CCNA2 | 15357 | 2502 | 0.196 | 0.0583 | No | ||
15 | CDK6 | 16600 | 3329 | 0.072 | 0.0147 | No | ||
16 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 3347 | 0.070 | 0.0148 | No | ||
17 | BCL2L11 | 2790 14861 | 3579 | 0.055 | 0.0031 | No | ||
18 | CD5 | 23741 | 3777 | 0.046 | -0.0069 | No | ||
19 | RAPGEF1 | 4218 2860 | 3945 | 0.040 | -0.0154 | No | ||
20 | AKT1 | 8568 | 4202 | 0.032 | -0.0288 | No | ||
21 | PIK3R2 | 18850 | 4225 | 0.031 | -0.0295 | No | ||
22 | BCAR1 | 18741 | 4267 | 0.031 | -0.0313 | No | ||
23 | SHC1 | 9813 9812 5430 | 4437 | 0.027 | -0.0401 | No | ||
24 | ITK | 4934 | 4889 | 0.020 | -0.0642 | No | ||
25 | IKBKG | 2570 2562 4908 | 5311 | 0.016 | -0.0867 | No | ||
26 | NCK1 | 9447 5152 | 6001 | 0.011 | -0.1238 | No | ||
27 | CR2 | 3942 13707 | 6218 | 0.010 | -0.1353 | No | ||
28 | ACTR3 | 13166 | 6258 | 0.010 | -0.1373 | No | ||
29 | ZAP70 | 14271 4042 | 6326 | 0.009 | -0.1408 | No | ||
30 | PRKCE | 9575 | 7970 | 0.004 | -0.2295 | No | ||
31 | DAPP1 | 11159 6445 6446 | 8473 | 0.003 | -0.2566 | No | ||
32 | PPP3CA | 1863 5284 | 9030 | 0.001 | -0.2867 | No | ||
33 | LYN | 16281 | 9749 | -0.001 | -0.3255 | No | ||
34 | PLCG1 | 14753 | 9774 | -0.001 | -0.3268 | No | ||
35 | MAPK4 | 23409 | 9850 | -0.001 | -0.3308 | No | ||
36 | CDK7 | 21365 | 10034 | -0.001 | -0.3407 | No | ||
37 | ACTR2 | 20523 | 10131 | -0.002 | -0.3458 | No | ||
38 | PPP3R1 | 9611 489 | 10273 | -0.002 | -0.3534 | No | ||
39 | NFATC2 | 5168 2866 | 10619 | -0.003 | -0.3720 | No | ||
40 | DOK1 | 17104 1018 1177 | 10626 | -0.003 | -0.3723 | No | ||
41 | SOS1 | 5476 | 10751 | -0.003 | -0.3790 | No | ||
42 | PIP5K1C | 5250 19929 | 11473 | -0.005 | -0.4179 | No | ||
43 | PIK3R1 | 3170 | 11690 | -0.006 | -0.4295 | No | ||
44 | CBL | 19154 | 11840 | -0.006 | -0.4374 | No | ||
45 | PTPN11 | 5326 16391 9660 | 12084 | -0.007 | -0.4505 | No | ||
46 | CREB1 | 3990 8782 4558 4093 | 12093 | -0.007 | -0.4508 | No | ||
47 | CRK | 4559 1249 | 13772 | -0.019 | -0.5412 | No | ||
48 | LCP2 | 4988 9268 | 14091 | -0.023 | -0.5581 | No | ||
49 | GAB2 | 1821 18184 2025 | 14144 | -0.024 | -0.5606 | No | ||
50 | VAV2 | 5848 2670 | 14223 | -0.025 | -0.5644 | No | ||
51 | PRKD1 | 2074 21075 | 14272 | -0.026 | -0.5667 | No | ||
52 | PRKCQ | 2873 2831 | 14811 | -0.040 | -0.5952 | No | ||
53 | GSK3A | 405 | 14840 | -0.041 | -0.5961 | No | ||
54 | CDK4 | 3424 19859 | 14882 | -0.042 | -0.5977 | No | ||
55 | FYN | 3375 3395 20052 | 15046 | -0.049 | -0.6059 | No | ||
56 | RPS6KB1 | 7815 1207 13040 | 15086 | -0.051 | -0.6073 | No | ||
57 | ATF2 | 4418 2759 | 15318 | -0.063 | -0.6189 | No | ||
58 | PTPRC | 5327 9662 | 15455 | -0.074 | -0.6252 | No | ||
59 | PDK2 | 20285 | 15503 | -0.079 | -0.6266 | No | ||
60 | CASP9 | 16001 2410 2458 | 15518 | -0.080 | -0.6263 | No | ||
61 | ITPR2 | 9194 | 15655 | -0.091 | -0.6323 | No | ||
62 | HCK | 14787 | 15902 | -0.120 | -0.6440 | No | ||
63 | CASP7 | 23826 | 15959 | -0.132 | -0.6451 | No | ||
64 | REL | 9716 | 16087 | -0.160 | -0.6498 | No | ||
65 | CARD11 | 8436 | 16126 | -0.169 | -0.6494 | No | ||
66 | RASA1 | 10174 | 16249 | -0.195 | -0.6533 | No | ||
67 | MAPK14 | 23313 | 16271 | -0.200 | -0.6516 | No | ||
68 | CD22 | 17881 | 16272 | -0.200 | -0.6488 | No | ||
69 | NFATC3 | 5169 | 16282 | -0.202 | -0.6465 | No | ||
70 | BTK | 24061 | 16291 | -0.204 | -0.6441 | No | ||
71 | PRKCD | 21897 | 16416 | -0.233 | -0.6475 | No | ||
72 | MAP4K1 | 18313 | 16669 | -0.306 | -0.6568 | No | ||
73 | TEC | 16514 | 16770 | -0.340 | -0.6575 | Yes | ||
74 | CD19 | 17640 | 16772 | -0.341 | -0.6527 | Yes | ||
75 | SOS2 | 21049 | 16783 | -0.343 | -0.6485 | Yes | ||
76 | PIK3AP1 | 23679 | 16853 | -0.375 | -0.6469 | Yes | ||
77 | GRB2 | 20149 | 16888 | -0.389 | -0.6433 | Yes | ||
78 | MAPK3 | 6458 11170 | 17011 | -0.437 | -0.6438 | Yes | ||
79 | CCND2 | 16987 | 17264 | -0.529 | -0.6500 | Yes | ||
80 | SH3BP2 | 16874 | 17424 | -0.609 | -0.6500 | Yes | ||
81 | WAS | 24193 | 17444 | -0.625 | -0.6423 | Yes | ||
82 | RASGRP3 | 10767 | 17489 | -0.648 | -0.6356 | Yes | ||
83 | GSK3B | 22761 | 17503 | -0.658 | -0.6270 | Yes | ||
84 | FCGR2B | 8959 | 17509 | -0.661 | -0.6181 | Yes | ||
85 | PTPN18 | 14279 | 17517 | -0.665 | -0.6091 | Yes | ||
86 | SYK | 21636 | 17551 | -0.690 | -0.6012 | Yes | ||
87 | LAT2 | 16351 | 17564 | -0.695 | -0.5921 | Yes | ||
88 | RELA | 23783 | 17583 | -0.705 | -0.5832 | Yes | ||
89 | RB1 | 21754 | 17584 | -0.706 | -0.5733 | Yes | ||
90 | CCND3 | 4489 4490 | 17695 | -0.788 | -0.5682 | Yes | ||
91 | JUN | 15832 | 17701 | -0.791 | -0.5574 | Yes | ||
92 | CRKL | 4560 | 17704 | -0.794 | -0.5463 | Yes | ||
93 | VAV1 | 23173 | 17823 | -0.886 | -0.5403 | Yes | ||
94 | HCLS1 | 22770 | 17891 | -0.942 | -0.5307 | Yes | ||
95 | CD81 | 8719 | 17930 | -0.995 | -0.5188 | Yes | ||
96 | NFKBIA | 21065 | 18048 | -1.142 | -0.5091 | Yes | ||
97 | CSK | 8805 | 18077 | -1.181 | -0.4941 | Yes | ||
98 | BCL10 | 15397 | 18079 | -1.187 | -0.4775 | Yes | ||
99 | PDPK1 | 23097 | 18082 | -1.189 | -0.4609 | Yes | ||
100 | PTK2B | 21776 | 18085 | -1.193 | -0.4443 | Yes | ||
101 | GAB1 | 18828 | 18157 | -1.275 | -0.4302 | Yes | ||
102 | CD79A | 18342 | 18161 | -1.285 | -0.4124 | Yes | ||
103 | CBLB | 5531 22734 | 18177 | -1.322 | -0.3946 | Yes | ||
104 | HDAC5 | 1480 20205 | 18194 | -1.345 | -0.3766 | Yes | ||
105 | CD79B | 20185 1309 | 18237 | -1.441 | -0.3587 | Yes | ||
106 | LCK | 15746 | 18240 | -1.451 | -0.3385 | Yes | ||
107 | MAPKAPK2 | 13838 | 18287 | -1.556 | -0.3191 | Yes | ||
108 | PTPN6 | 17002 | 18450 | -2.074 | -0.2988 | Yes | ||
109 | NEDD9 | 3206 21483 | 18492 | -2.359 | -0.2679 | Yes | ||
110 | GTF2I | 16353 5491 9863 3280 3184 | 18507 | -2.514 | -0.2334 | Yes | ||
111 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 18536 | -2.749 | -0.1964 | Yes | ||
112 | BCL6 | 22624 | 18554 | -3.060 | -0.1544 | Yes | ||
113 | CD72 | 8718 | 18565 | -3.348 | -0.1080 | Yes | ||
114 | MAPK1 | 1642 11167 | 18579 | -3.793 | -0.0555 | Yes | ||
115 | BLK | 3205 21791 | 18586 | -4.095 | 0.0016 | Yes |