Details for gene set HSA04810_REGULATION_OF_ACTIN

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos
Phenotype	phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos
Upregulated in class	transDMpreB
GeneSet	HSA04810_REGULATION_OF_ACTIN_CYTOSKELETON
Enrichment Score (ES)	0.6208302
Normalized Enrichment Score (NES)	1.5188205
Nominal p-value	0.0018903592
FDR q-value	0.6951547
FWER p-Value	0.975

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MYH9	2252 2244	1	5.596	0.2202	Yes
2	FGF13	4720 8963 2627	16	2.188	0.3056	Yes
3	ITGB7	22112	146	0.951	0.3360	Yes
4	LIMK2	9278 1296	181	0.849	0.3676	Yes
5	IQGAP1	6619	249	0.711	0.3919	Yes
6	PIK3CG	6635	307	0.628	0.4136	Yes
7	SLC9A1	16053	425	0.520	0.4277	Yes
8	ACTN4	17905 1798 1983	442	0.505	0.4467	Yes
9	ROCK1	5386	458	0.495	0.4654	Yes
10	WAS	24193	554	0.440	0.4776	Yes
11	RAC2	22217	577	0.430	0.4933	Yes
12	ARPC1B	3512 8628	735	0.346	0.4984	Yes
13	WASL	17203	770	0.333	0.5097	Yes
14	PAK4	17909	822	0.317	0.5194	Yes
15	ARHGEF6	13297 13104	902	0.293	0.5266	Yes
16	ARPC2	14225	929	0.283	0.5364	Yes
17	PPP1R12A	3354 19886	936	0.281	0.5471	Yes
18	VCL	22083	1039	0.252	0.5515	Yes
19	WASF2	6326	1054	0.248	0.5605	Yes
20	RRAS	18256	1108	0.230	0.5667	Yes
21	MAP2K1	19082	1120	0.227	0.5750	Yes
22	TIAM1	22547	1135	0.225	0.5831	Yes
23	MSN	5122	1213	0.209	0.5872	Yes
24	MAPK3	6458 11170	1268	0.198	0.5920	Yes
25	CSK	8805	1270	0.197	0.5997	Yes
26	ARPC5L	15017	1362	0.179	0.6018	Yes
27	RAF1	17035	1454	0.166	0.6034	Yes
28	SOS2	21049	1570	0.149	0.6030	Yes
29	VAV1	23173	1577	0.148	0.6085	Yes
30	PTK2	22271	1691	0.130	0.6075	Yes
31	GNA13	20617	1696	0.130	0.6124	Yes
32	GNG12	4789	1711	0.128	0.6167	Yes
33	MAP2K2	19933	1831	0.114	0.6147	Yes
34	ARAF	24367	1869	0.108	0.6169	Yes
35	ITGAL	9187	1927	0.100	0.6178	Yes
36	EGF	15169	1943	0.098	0.6208	Yes
37	ITGB2	19978	2033	0.089	0.6195	No
38	RRAS2	12431	2151	0.079	0.6163	No
39	ROCK2	21309 5387	2573	0.052	0.5955	No
40	PXN	5339 3573	2632	0.049	0.5943	No
41	ITGA10	15493	2642	0.049	0.5957	No
42	CYFIP1	9814	2689	0.047	0.5951	No
43	PIP5K3	14234	2807	0.043	0.5904	No
44	FGF3	17997	2935	0.039	0.5851	No
45	PDGFRB	23539	2973	0.037	0.5845	No
46	PIK3CD	9563	3036	0.036	0.5826	No
47	CFL2	2155 21069	3082	0.034	0.5815	No
48	FGF17	21757	3120	0.034	0.5808	No
49	ITGA6	4930	3320	0.029	0.5711	No
50	BDKRB1	19418	3396	0.027	0.5681	No
51	ARPC4	12642	3567	0.024	0.5598	No
52	PPP1CC	9609 5283	3588	0.024	0.5597	No
53	PAK1	9527	3642	0.023	0.5577	No
54	ITGB3	20631	3749	0.021	0.5528	No
55	PFN2	15337 1818	3810	0.020	0.5503	No
56	PFN3	7968	3844	0.020	0.5493	No
57	PIP5K1C	5250 19929	3871	0.020	0.5487	No
58	PFN1	9555	3886	0.019	0.5487	No
59	VAV2	5848 2670	3933	0.019	0.5469	No
60	CD14	23452	3948	0.019	0.5469	No
61	SSH3	3709 10890	4063	0.017	0.5414	No
62	SSH1	10540	4137	0.017	0.5381	No
63	FGF18	4721 1351	4227	0.016	0.5339	No
64	MYL2	16713	4258	0.015	0.5329	No
65	MYL7	9437	4285	0.015	0.5320	No
66	FGD3	11399	4302	0.015	0.5318	No
67	ARHGEF7	3823	4504	0.013	0.5214	No
68	APC2	10704	4508	0.013	0.5218	No
69	FGF10	4719 8962	4612	0.013	0.5167	No
70	FGF5	16785	4635	0.012	0.5160	No
71	RAC3	20561	4699	0.012	0.5130	No
72	LIMK1	16350	4780	0.012	0.5091	No
73	BDKRB2	21163	4889	0.011	0.5037	No
74	FGF8	23656	4892	0.011	0.5040	No
75	ITGA5	22105	4968	0.010	0.5004	No
76	MRAS	9409	5175	0.009	0.4896	No
77	PDGFA	5237	5197	0.009	0.4888	No
78	NCKAP1	6947	5349	0.009	0.4810	No
79	FGFR1	3789 8968	5478	0.008	0.4744	No
80	FGFR2	1917 4722 1119	5527	0.008	0.4721	No
81	FGF14	21716 3005 3463	5530	0.008	0.4723	No
82	SOS1	5476	5736	0.007	0.4614	No
83	ITGAX	18058	5823	0.007	0.4570	No
84	TMSB4X	24005	5847	0.007	0.4561	No
85	ITGA2B	9186	5858	0.007	0.4558	No
86	BAIAP2	449 4236	5890	0.007	0.4544	No
87	CDC42	4503 8722 4504 2465	5905	0.007	0.4539	No
88	PIK3R5	11507	6008	0.006	0.4486	No
89	ITGAV	4931	6031	0.006	0.4476	No
90	RHOA	8624 4409 4410	6567	0.005	0.4188	No
91	ARHGEF12	19156	6770	0.004	0.4080	No
92	FGF2	15608	6858	0.004	0.4035	No
93	FGF4	8964	6886	0.004	0.4021	No
94	WASF1	13514	6958	0.004	0.3984	No
95	ITGB6	14581 2809	6996	0.004	0.3966	No
96	CHRM4	14945	6998	0.004	0.3967	No
97	TIAM2	10759	7125	0.003	0.3899	No
98	FGFR3	8969 3566	7143	0.003	0.3892	No
99	MOS	16254	7390	0.003	0.3759	No
100	GSN	2784	7437	0.003	0.3735	No
101	CRK	4559 1249	7552	0.002	0.3674	No
102	FGF20	18892	7590	0.002	0.3655	No
103	MYLC2PL	16670	7626	0.002	0.3637	No
104	PIK3R1	3170	7781	0.002	0.3554	No
105	FGF11	20383	8220	0.001	0.3317	No
106	ITGA11	6677 11449	8300	0.001	0.3274	No
107	FGF7	8965	8584	0.000	0.3121	No
108	FGF12	1723 22621	8735	-0.000	0.3040	No
109	CHRM2	10840	8814	-0.000	0.2998	No
110	MYLK	22778 4213	8871	-0.000	0.2967	No
111	ITGA4	4929	8961	-0.001	0.2919	No
112	MYH10	8077	8967	-0.001	0.2917	No
113	CHRM5	10038	8995	-0.001	0.2902	No
114	PDGFB	22199 2311	9170	-0.001	0.2808	No
115	FGF16	24270	9185	-0.001	0.2801	No
116	MYL9	14767 2659	9249	-0.001	0.2768	No
117	PAK7	14417	9537	-0.002	0.2613	No
118	ARHGEF1	1952 18343 3996	9676	-0.002	0.2539	No
119	FGD1	24228	9726	-0.002	0.2513	No
120	ABI2	4037 6830	9876	-0.003	0.2433	No
121	CHRM3	21547	9911	-0.003	0.2416	No
122	FGF21	17830	10311	-0.004	0.2201	No
123	PDGFRA	16824	10921	-0.005	0.1873	No
124	ITGA7	19835	11083	-0.006	0.1788	No
125	MYH14	17845	11230	-0.006	0.1711	No
126	ITGAE	20791 1481 1397 1380 1278 1238 1359	11457	-0.007	0.1591	No
127	PIK3CA	9562	11488	-0.007	0.1578	No
128	ITGA3	20284	11500	-0.007	0.1574	No
129	EGFR	1329 20944	12193	-0.009	0.1203	No
130	PPP1CB	5282 3529 3504	12226	-0.010	0.1189	No
131	PAK3	9528	12267	-0.010	0.1171	No
132	CHRM1	23943	12308	-0.010	0.1153	No
133	NRAS	5191	12479	-0.011	0.1066	No
134	ITGAM	9188	12542	-0.011	0.1036	No
135	PIK3R2	18850	12644	-0.012	0.0986	No
136	GNA12	9023	12834	-0.013	0.0889	No
137	ITGA8	14685	12976	-0.014	0.0817	No
138	ARPC5	12580 7487	13183	-0.015	0.0712	No
139	ACTN2	21545	13284	-0.016	0.0664	No
140	FGF23	17275	13522	-0.018	0.0542	No
141	ACTN3	23967 8540	13897	-0.021	0.0348	No
142	FGF1	1994 23447	13978	-0.022	0.0313	No
143	PIK3R3	5248	14193	-0.025	0.0207	No
144	FGF9	8966	14196	-0.025	0.0216	No
145	FGFR4	3226	14283	-0.026	0.0179	No
146	FGF22	12468 7385	14648	-0.033	-0.0005	No
147	ITGB4	9669 159	14901	-0.039	-0.0126	No
148	FN1	4091 4094 971 13929	15113	-0.044	-0.0224	No
149	ITGB5	4932	15298	-0.049	-0.0304	No
150	APC	4396 2022	15406	-0.053	-0.0341	No
151	VAV3	1774 1848 15443	15682	-0.064	-0.0465	No
152	ITGB1	3872 18411	15782	-0.069	-0.0492	No
153	MYLPF	18069	15826	-0.071	-0.0487	No
154	PIP5K1B	5251 1841	15862	-0.073	-0.0477	No
155	SSH2	6202	15880	-0.074	-0.0458	No
156	CFL1	4516	15903	-0.075	-0.0440	No
157	KRAS	9247	15933	-0.076	-0.0426	No
158	SCIN	21079	15974	-0.078	-0.0416	No
159	F2	14524	16051	-0.082	-0.0425	No
160	ITGA9	19280	16121	-0.086	-0.0429	No
161	ARPC3	12109	16135	-0.087	-0.0401	No
162	PPP1CA	9608 3756 914 909	16206	-0.093	-0.0403	No
163	PFN4	11798	16692	-0.131	-0.0614	No
164	PIP5K1A	23708	16742	-0.135	-0.0587	No
165	PAK2	10310 5875	16761	-0.137	-0.0543	No
166	HRAS	4868	16826	-0.145	-0.0521	No
167	RAC1	16302	16844	-0.147	-0.0472	No
168	CYFIP2	20485 8045	17019	-0.167	-0.0501	No
169	CRKL	4560	17157	-0.181	-0.0504	No
170	PIK3CB	19030	17205	-0.186	-0.0456	No
171	MAPK1	1642 11167	17642	-0.244	-0.0597	No
172	DIAPH3	7117	17752	-0.264	-0.0552	No
173	ARPC1A	3541 16628 3519	18073	-0.346	-0.0589	No
174	F2R	21386	18155	-0.392	-0.0479	No
175	BCAR1	18741	18276	-0.468	-0.0360	No
176	RDX	9712 5371	18544	-1.380	0.0039	No