Dataset | Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos |
Phenotype | phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos |
Upregulated in class | transDMpreB |
GeneSet | HSA04630_JAK_STAT_SIGNALING_PATHWAY |
Enrichment Score (ES) | 0.5960601 |
Normalized Enrichment Score (NES) | 1.4070511 |
Nominal p-value | 0.022530328 |
FDR q-value | 0.9442537 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | IL10 | 14145 1510 1553 22902 | 14 | 2.242 | 0.1811 | Yes | ||
2 | PIK3CG | 6635 | 307 | 0.628 | 0.2163 | Yes | ||
3 | IL10RA | 19137 | 406 | 0.534 | 0.2542 | Yes | ||
4 | CREBBP | 22682 8783 | 416 | 0.525 | 0.2963 | Yes | ||
5 | CSF2RA | 23631 | 431 | 0.514 | 0.3373 | Yes | ||
6 | PTPN6 | 17002 | 489 | 0.478 | 0.3729 | Yes | ||
7 | CCND3 | 4489 4490 | 509 | 0.469 | 0.4100 | Yes | ||
8 | CCND1 | 4487 4488 8707 17535 | 581 | 0.427 | 0.4408 | Yes | ||
9 | STAT3 | 5525 9906 | 746 | 0.342 | 0.4596 | Yes | ||
10 | IL12A | 4913 | 864 | 0.303 | 0.4779 | Yes | ||
11 | TYK2 | 12058 19215 | 955 | 0.274 | 0.4953 | Yes | ||
12 | SOCS2 | 5694 | 984 | 0.267 | 0.5154 | Yes | ||
13 | GRB2 | 20149 | 1140 | 0.224 | 0.5252 | Yes | ||
14 | CCND2 | 16987 | 1183 | 0.215 | 0.5403 | Yes | ||
15 | STAT2 | 19840 | 1216 | 0.208 | 0.5555 | Yes | ||
16 | JAK1 | 15827 | 1502 | 0.159 | 0.5529 | Yes | ||
17 | JAK3 | 9198 4936 | 1549 | 0.151 | 0.5626 | Yes | ||
18 | SOS2 | 21049 | 1570 | 0.149 | 0.5736 | Yes | ||
19 | PIAS4 | 19681 | 1595 | 0.146 | 0.5842 | Yes | ||
20 | IFNGR1 | 20083 | 1753 | 0.123 | 0.5857 | Yes | ||
21 | PIM1 | 23308 | 1846 | 0.111 | 0.5897 | Yes | ||
22 | IFNGR2 | 9155 22702 | 1888 | 0.105 | 0.5961 | Yes | ||
23 | STAT5A | 20664 | 2200 | 0.075 | 0.5853 | No | ||
24 | IL9R | 20505 | 2373 | 0.063 | 0.5812 | No | ||
25 | IFNA14 | 11917 | 2890 | 0.040 | 0.5565 | No | ||
26 | IL6R | 1862 4919 | 2912 | 0.040 | 0.5586 | No | ||
27 | IL6ST | 4920 | 2926 | 0.039 | 0.5611 | No | ||
28 | PIK3CD | 9563 | 3036 | 0.036 | 0.5581 | No | ||
29 | CISH | 8743 | 3309 | 0.029 | 0.5457 | No | ||
30 | CLCF1 | 12160 3742 | 3402 | 0.027 | 0.5429 | No | ||
31 | IL15RA | 2899 2717 15118 2792 | 3509 | 0.025 | 0.5392 | No | ||
32 | CBL | 19154 | 3514 | 0.025 | 0.5409 | No | ||
33 | JAK2 | 23893 9197 3706 | 3648 | 0.023 | 0.5356 | No | ||
34 | STAM2 | 7095 2845 | 3783 | 0.021 | 0.5300 | No | ||
35 | IL24 | 976 13841 | 3819 | 0.020 | 0.5298 | No | ||
36 | PIAS3 | 15491 672 1906 | 3854 | 0.020 | 0.5295 | No | ||
37 | IL4R | 18085 | 3863 | 0.020 | 0.5307 | No | ||
38 | STAT6 | 19854 9909 | 3963 | 0.019 | 0.5268 | No | ||
39 | SPRY1 | 15606 1901 | 3987 | 0.018 | 0.5271 | No | ||
40 | IL4 | 9174 | 4010 | 0.018 | 0.5273 | No | ||
41 | LEPR | 2531 2349 | 4104 | 0.017 | 0.5237 | No | ||
42 | MYC | 22465 9435 | 4133 | 0.017 | 0.5235 | No | ||
43 | IL3 | 20453 | 4232 | 0.016 | 0.5195 | No | ||
44 | BCL2L1 | 4440 2930 8652 | 4351 | 0.014 | 0.5143 | No | ||
45 | IFNG | 19869 | 4409 | 0.014 | 0.5123 | No | ||
46 | CSF3 | 1394 20671 | 4462 | 0.014 | 0.5106 | No | ||
47 | IL6 | 16895 | 4767 | 0.012 | 0.4951 | No | ||
48 | EPO | 8911 | 4801 | 0.011 | 0.4942 | No | ||
49 | IFNA4 | 9150 | 4940 | 0.011 | 0.4876 | No | ||
50 | IL22RA1 | 16037 | 5503 | 0.008 | 0.4579 | No | ||
51 | STAT4 | 14251 9907 | 5535 | 0.008 | 0.4569 | No | ||
52 | PIAS2 | 1948 5102 | 5586 | 0.008 | 0.4548 | No | ||
53 | SOS1 | 5476 | 5736 | 0.007 | 0.4473 | No | ||
54 | IL15 | 18826 3801 | 5774 | 0.007 | 0.4459 | No | ||
55 | SOCS5 | 1619 23141 | 5821 | 0.007 | 0.4439 | No | ||
56 | IFNAR1 | 22703 | 5926 | 0.007 | 0.4388 | No | ||
57 | IL5 | 20884 10220 | 6004 | 0.006 | 0.4352 | No | ||
58 | PIK3R5 | 11507 | 6008 | 0.006 | 0.4355 | No | ||
59 | LEP | 17505 | 6042 | 0.006 | 0.4342 | No | ||
60 | IL23R | 17127 | 6058 | 0.006 | 0.4339 | No | ||
61 | IL11 | 17981 | 6556 | 0.005 | 0.4074 | No | ||
62 | IL21 | 12241 | 6694 | 0.004 | 0.4004 | No | ||
63 | IL23A | 19598 | 6799 | 0.004 | 0.3951 | No | ||
64 | CBLC | 17938 | 7212 | 0.003 | 0.3730 | No | ||
65 | IFNA7 | 9152 | 7241 | 0.003 | 0.3717 | No | ||
66 | IL12B | 20918 | 7351 | 0.003 | 0.3661 | No | ||
67 | IL7 | 4921 | 7473 | 0.002 | 0.3597 | No | ||
68 | PRL | 21690 | 7530 | 0.002 | 0.3569 | No | ||
69 | IFNK | 11837 | 7563 | 0.002 | 0.3553 | No | ||
70 | PIK3R1 | 3170 | 7781 | 0.002 | 0.3437 | No | ||
71 | GHR | 22336 | 8010 | 0.001 | 0.3315 | No | ||
72 | IFNB1 | 15846 | 8030 | 0.001 | 0.3306 | No | ||
73 | IL13RA1 | 24361 | 8122 | 0.001 | 0.3257 | No | ||
74 | CSF2 | 20454 | 8345 | 0.001 | 0.3138 | No | ||
75 | LIFR | 22515 9277 | 8870 | -0.000 | 0.2855 | No | ||
76 | EPOR | 19204 | 8896 | -0.000 | 0.2841 | No | ||
77 | IL19 | 13839 | 8915 | -0.000 | 0.2832 | No | ||
78 | IL13 | 20461 | 9345 | -0.001 | 0.2601 | No | ||
79 | IFNA13 | 15844 | 9413 | -0.002 | 0.2566 | No | ||
80 | IL13RA2 | 24036 | 9421 | -0.002 | 0.2564 | No | ||
81 | IL20 | 13840 | 9484 | -0.002 | 0.2532 | No | ||
82 | IL22 | 11948 | 9572 | -0.002 | 0.2486 | No | ||
83 | AKT1 | 8568 | 9661 | -0.002 | 0.2440 | No | ||
84 | CTF1 | 18064 | 9840 | -0.003 | 0.2346 | No | ||
85 | IL2RB | 22219 | 10134 | -0.003 | 0.2190 | No | ||
86 | CNTFR | 2515 15906 | 10145 | -0.003 | 0.2188 | No | ||
87 | TPO | 21092 | 10356 | -0.004 | 0.2077 | No | ||
88 | IL9 | 21444 | 10435 | -0.004 | 0.2038 | No | ||
89 | SPRY4 | 23448 | 10633 | -0.004 | 0.1935 | No | ||
90 | SPRY2 | 21725 | 11036 | -0.006 | 0.1722 | No | ||
91 | MPL | 15780 | 11074 | -0.006 | 0.1707 | No | ||
92 | AKT2 | 4365 4366 | 11243 | -0.006 | 0.1621 | No | ||
93 | TSLP | 23604 1955 | 11351 | -0.006 | 0.1568 | No | ||
94 | SPRED2 | 8539 4332 | 11403 | -0.007 | 0.1546 | No | ||
95 | PIK3CA | 9562 | 11488 | -0.007 | 0.1506 | No | ||
96 | STAT5B | 20222 | 11851 | -0.008 | 0.1316 | No | ||
97 | SOCS7 | 5308 20679 | 11859 | -0.008 | 0.1319 | No | ||
98 | PTPN11 | 5326 16391 9660 | 12011 | -0.009 | 0.1244 | No | ||
99 | IFNA2 | 9149 | 12196 | -0.009 | 0.1153 | No | ||
100 | IFNAR2 | 22705 1699 | 12350 | -0.010 | 0.1078 | No | ||
101 | PIK3R2 | 18850 | 12644 | -0.012 | 0.0929 | No | ||
102 | IL2 | 15354 | 12851 | -0.013 | 0.0828 | No | ||
103 | STAM | 2912 15117 | 12926 | -0.013 | 0.0799 | No | ||
104 | IL12RB2 | 17128 | 13033 | -0.014 | 0.0753 | No | ||
105 | IFNA6 | 17749 | 13107 | -0.014 | 0.0725 | No | ||
106 | IFNA1 | 9147 | 13280 | -0.016 | 0.0644 | No | ||
107 | IL22RA2 | 20082 | 13468 | -0.017 | 0.0557 | No | ||
108 | OSMR | 22333 | 13561 | -0.018 | 0.0522 | No | ||
109 | IFNA5 | 9151 | 13605 | -0.018 | 0.0514 | No | ||
110 | IFNE1 | 15842 | 13692 | -0.019 | 0.0483 | No | ||
111 | IL5RA | 17051 | 13740 | -0.020 | 0.0473 | No | ||
112 | IL2RG | 24096 | 13898 | -0.021 | 0.0406 | No | ||
113 | CSF3R | 8804 8803 2326 4565 | 13924 | -0.022 | 0.0410 | No | ||
114 | LIF | 956 667 20960 | 14036 | -0.023 | 0.0368 | No | ||
115 | CNTF | 3741 8761 3680 3736 | 14051 | -0.023 | 0.0379 | No | ||
116 | CRLF2 | 16442 | 14088 | -0.024 | 0.0379 | No | ||
117 | PIK3R3 | 5248 | 14193 | -0.025 | 0.0343 | No | ||
118 | PRLR | 9620 5291 | 14216 | -0.025 | 0.0352 | No | ||
119 | IL28RA | 10823 16038 | 14481 | -0.030 | 0.0233 | No | ||
120 | SOCS1 | 4522 | 14964 | -0.040 | 0.0005 | No | ||
121 | SPRED1 | 4331 | 15460 | -0.055 | -0.0219 | No | ||
122 | IL12RB1 | 3916 18582 | 15678 | -0.064 | -0.0284 | No | ||
123 | PIAS1 | 7126 | 15739 | -0.067 | -0.0262 | No | ||
124 | IL21R | 1398 18084 | 15787 | -0.069 | -0.0231 | No | ||
125 | STAT1 | 3936 5524 | 15868 | -0.073 | -0.0215 | No | ||
126 | SOCS4 | 7424 | 16118 | -0.086 | -0.0280 | No | ||
127 | IL10RB | 9169 | 16561 | -0.118 | -0.0424 | No | ||
128 | IL3RA | 22091 | 16784 | -0.140 | -0.0430 | No | ||
129 | SOCS3 | 20131 | 16965 | -0.160 | -0.0398 | No | ||
130 | CBLB | 5531 22734 | 16986 | -0.163 | -0.0276 | No | ||
131 | IL2RA | 4918 | 17189 | -0.184 | -0.0236 | No | ||
132 | PIK3CB | 19030 | 17205 | -0.186 | -0.0094 | No | ||
133 | AKT3 | 13739 982 | 17357 | -0.204 | -0.0010 | No | ||
134 | IL7R | 9175 4922 | 18473 | -0.851 | 0.0077 | No |