Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos
Phenotype	phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos
Upregulated in class	DMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	-0.60365
Normalized Enrichment Score (NES)	-1.4764496
Nominal p-value	0.009009009
FDR q-value	0.57146984
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PKM2	3642 9573	88	1.222	0.0541	No
2	HPRT1	2655 24339 408	104	1.135	0.1079	No
3	POLD3	17742	648	0.385	0.0971	No
4	AK2	8563 2479 16073	869	0.301	0.0997	No
5	POLR1A	9749 5393	933	0.282	0.1098	No
6	POLA2	23988	1162	0.219	0.1080	No
7	POLD4	12822	1173	0.217	0.1180	No
8	POLE	16755	1363	0.178	0.1163	No
9	POLD1	17847	1436	0.169	0.1206	No
10	RRM2	5401 5400	1474	0.163	0.1264	No
11	PRPS2	24003	1704	0.129	0.1202	No
12	NT5C	20151	2016	0.091	0.1078	No
13	RRM1	18163	2508	0.056	0.0839	No
14	PDE8A	18202	2513	0.056	0.0863	No
15	XDH	22897	2519	0.055	0.0887	No
16	PDE2A	18170	2528	0.055	0.0909	No
17	NME1	9467	3022	0.036	0.0660	No
18	PDE7A	9544 1788	3270	0.030	0.0541	No
19	ECGF1	22160	3299	0.029	0.0540	No
20	CANT1	13304	3444	0.026	0.0474	No
21	PDE4D	10722 6235	3548	0.024	0.0430	No
22	POLR3A	21900	3553	0.024	0.0439	No
23	NT5E	19360 18702	3931	0.019	0.0245	No
24	AMPD1	5051	3942	0.019	0.0248	No
25	POLR2C	9750	4477	0.014	-0.0034	No
26	ENTPD6	4496 2678	4479	0.014	-0.0028	No
27	GDA	4764	4643	0.012	-0.0110	No
28	PDE6H	17257	4705	0.012	-0.0137	No
29	ITPA	9193	4773	0.012	-0.0168	No
30	ADCY8	22281	4811	0.011	-0.0183	No
31	NPR2	16230	4966	0.011	-0.0261	No
32	IMPDH1	17197 1131	5232	0.009	-0.0400	No
33	PAPSS2	6258	5395	0.008	-0.0483	No
34	POLE2	21053	5893	0.007	-0.0749	No
35	ADCY4	2980 21818	5963	0.006	-0.0783	No
36	PDE4C	8481	6108	0.006	-0.0858	No
37	ADCY9	22680	6176	0.006	-0.0892	No
38	ENTPD2	8713	6590	0.005	-0.1113	No
39	AMPD2	1931 15197	6696	0.004	-0.1168	No
40	PKLR	1850 15545	7039	0.003	-0.1351	No
41	POLR3K	12447 7372	7065	0.003	-0.1363	No
42	NT5C1B	21315	7312	0.003	-0.1494	No
43	POLE3	7200	7445	0.003	-0.1565	No
44	GUCY1A3	7216 12245 15310	7507	0.002	-0.1597	No
45	GUCY2F	24045	7763	0.002	-0.1734	No
46	ENTPD3	19266	8358	0.001	-0.2055	No
47	ENTPD8	12996	8370	0.001	-0.2060	No
48	PDE10A	23387	8440	0.000	-0.2097	No
49	NPR1	9480	8528	0.000	-0.2144	No
50	AK5	6042	8636	0.000	-0.2202	No
51	ALLC	21093 2130	8861	-0.000	-0.2323	No
52	GUCY1A2	19580	8869	-0.000	-0.2327	No
53	POLA1	24112	8962	-0.001	-0.2376	No
54	PDE1C	5235	9187	-0.001	-0.2497	No
55	NT5M	8345 4175	9267	-0.001	-0.2539	No
56	GUCY2C	1140 16954	9453	-0.002	-0.2638	No
57	POLR2B	16817	9609	-0.002	-0.2721	No
58	ENPP3	19803	9728	-0.002	-0.2784	No
59	RRM2B	6902 6903 11801	10429	-0.004	-0.3160	No
60	ADCY5	10312	10593	-0.004	-0.3246	No
61	PDE7B	19807	10623	-0.004	-0.3260	No
62	PDE11A	10805	10645	-0.005	-0.3269	No
63	PDE1A	9541 5234	10809	-0.005	-0.3355	No
64	ADK	3302 3454 8555	11116	-0.006	-0.3518	No
65	ADCY6	22139 2283 8551	11485	-0.007	-0.3713	No
66	ENTPD1	4495	11520	-0.007	-0.3729	No
67	PDE4A	3037 19542 3083 3023	11985	-0.009	-0.3975	No
68	POLR2A	5394	12103	-0.009	-0.4034	No
69	DGUOK	17099 1041	12216	-0.010	-0.4090	No
70	PDE9A	23301	12219	-0.010	-0.4087	No
71	GMPR	21651	12324	-0.010	-0.4138	No
72	AK1	4363	12484	-0.011	-0.4219	No
73	PDE6G	20119	12560	-0.011	-0.4254	No
74	PRIM1	19847	12641	-0.012	-0.4292	No
75	PDE5A	15431	12782	-0.012	-0.4362	No
76	AMPD3	4383 2110	13036	-0.014	-0.4492	No
77	ADCY7	8552 448	13095	-0.014	-0.4516	No
78	PDE8B	5756	13223	-0.015	-0.4578	No
79	GUCY1B3	15311	13230	-0.015	-0.4574	No
80	NUDT9	7897	13276	-0.016	-0.4590	No
81	ADCY2	21412	13579	-0.018	-0.4745	No
82	PDE3B	5236	13757	-0.020	-0.4831	No
83	IMPDH2	10730	14234	-0.026	-0.5076	No
84	POLR3H	13460 8135	14320	-0.027	-0.5109	No
85	GMPR2	2711	14523	-0.031	-0.5204	No
86	NME7	926 4101 14070 3986 3946 931	14626	-0.033	-0.5243	No
87	AK3L1	8564	14684	-0.034	-0.5258	No
88	PNPT1	20936	14879	-0.038	-0.5344	No
89	ADCY3	21329 894	15046	-0.042	-0.5414	No
90	PAICS	16820	15597	-0.061	-0.5682	No
91	RFC5	13005 7791	15627	-0.062	-0.5668	No
92	PDE4B	9543	15823	-0.071	-0.5739	No
93	POLE4	12441	15909	-0.075	-0.5749	No
94	PPAT	6081	16380	-0.104	-0.5953	No
95	ENPP1	19804	16437	-0.109	-0.5931	No
96	PDE6D	13897 3945	16633	-0.125	-0.5976	Yes
97	ENTPD4	7449	16687	-0.131	-0.5942	Yes
98	ENTPD5	4497	16727	-0.134	-0.5899	Yes
99	PAPSS1	15419	16848	-0.148	-0.5892	Yes
100	POLR2J	16672	16916	-0.155	-0.5854	Yes
101	ADSL	4358	17011	-0.166	-0.5825	Yes
102	GART	22543 1754	17097	-0.174	-0.5787	Yes
103	POLR3B	12875	17298	-0.198	-0.5800	Yes
104	POLD2	20537	17359	-0.205	-0.5734	Yes
105	ATIC	14231 3968	17375	-0.207	-0.5642	Yes
106	POLR1B	14857	17382	-0.208	-0.5546	Yes
107	POLR2I	12839	17404	-0.211	-0.5455	Yes
108	NT5C2	3768 8052	17418	-0.213	-0.5360	Yes
109	NUDT2	16239	17472	-0.221	-0.5282	Yes
110	ZNRD1	1491 22987	17501	-0.225	-0.5189	Yes
111	DCK	16808	17525	-0.228	-0.5092	Yes
112	ADA	2703 14361	17625	-0.242	-0.5029	Yes
113	GMPS	15578	17672	-0.250	-0.4933	Yes
114	PRPS1	24233	17760	-0.266	-0.4852	Yes
115	GUK1	20432	17837	-0.284	-0.4757	Yes
116	NME6	3139 19297	17867	-0.291	-0.4632	Yes
117	NUDT5	15121	17995	-0.322	-0.4546	Yes
118	NME2	9468	18007	-0.326	-0.4395	Yes
119	NT5C3	17136	18017	-0.329	-0.4241	Yes
120	POLR2G	23753	18082	-0.349	-0.4108	Yes
121	APRT	8620	18149	-0.389	-0.3956	Yes
122	NME4	23065 1577	18197	-0.418	-0.3781	Yes
123	POLR2E	3325 19699	18208	-0.425	-0.3582	Yes
124	FHIT	21920	18254	-0.457	-0.3386	Yes
125	POLR2H	10888	18302	-0.486	-0.3177	Yes
126	POLR2K	9413	18504	-1.001	-0.2803	Yes
127	ADSSL1	21136 2087	18568	-1.547	-0.2093	Yes
128	POLR1D	3593 3658 16623	18577	-1.857	-0.1203	Yes
129	NP	22027 9597 5273 5274	18597	-2.542	0.0010	Yes