Details for gene set REACTOME_REGULATION_OF_INSULIN

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos
Phenotype	phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos
Upregulated in class	DMpreB
GeneSet	REACTOME_REGULATION_OF_INSULIN_SECRETION
Enrichment Score (ES)	-0.6552446
Normalized Enrichment Score (NES)	-1.5417581
Nominal p-value	0.012
FDR q-value	0.77381253
FWER p-Value	0.996

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PKM2	3642 9573	88	1.222	0.0474	No
2	IQGAP1	6619	249	0.711	0.0690	No
3	GNAS	9025 2963 2752	376	0.559	0.0860	No
4	ETFA	4292 8495 3155	517	0.465	0.0983	No
5	VAMP2	20826	1082	0.237	0.0779	No
6	OGDH	9502 1412	1133	0.225	0.0848	No
7	PRKACB	15140	1613	0.143	0.0651	No
8	PFKFB3	2748	1771	0.121	0.0617	No
9	ATP5A1	23505	1815	0.115	0.0643	No
10	COX8A	8777	1862	0.108	0.0665	No
11	NDUFA10	7420	2014	0.091	0.0622	No
12	COX7A2L	9819	2102	0.083	0.0610	No
13	DLST	8131	2142	0.080	0.0623	No
14	MDH2	9399	2406	0.062	0.0507	No
15	PRKAR2B	5288 2107	3033	0.036	0.0185	No
16	SLC2A2	15623 1880 1855	3357	0.028	0.0022	No
17	ATP5B	19846	3368	0.027	0.0028	No
18	FFAR1	10583	3419	0.026	0.0012	No
19	NDUFB10	23084	3532	0.024	-0.0038	No
20	UQCRB	12545	3696	0.022	-0.0116	No
21	ATP5D	19949	3826	0.020	-0.0177	No
22	IDH3B	9299	4310	0.015	-0.0432	No
23	UQCRFS1	21499	4386	0.014	-0.0466	No
24	IDH3G	24132	4400	0.014	-0.0467	No
25	UQCRC1	10259	4648	0.012	-0.0596	No
26	SDHD	19125	5222	0.009	-0.0901	No
27	PDHX	14510	6497	0.005	-0.1587	No
28	NDUFS1	13940	6973	0.004	-0.1842	No
29	SDHA	12436	8267	0.001	-0.2540	No
30	PFKFB1	9552	9907	-0.003	-0.3424	No
31	CHRM3	21547	9911	-0.003	-0.3424	No
32	NDUFS7	19946	10993	-0.005	-0.4006	No
33	RAP1A	8467	11212	-0.006	-0.4121	No
34	NDUFB4	22596 7541	11294	-0.006	-0.4162	No
35	PDHB	12670 7548	11342	-0.006	-0.4185	No
36	SYT5	17986	11663	-0.007	-0.4355	No
37	GCG	14578	11670	-0.007	-0.4355	No
38	NDUFA3	18410	11824	-0.008	-0.4434	No
39	ADRA2A	4355	12489	-0.011	-0.4788	No
40	PGK1	9557 5244	12818	-0.013	-0.4960	No
41	SDHB	2348 12566 14880	12963	-0.014	-0.5032	No
42	NDUFA5	1076 7544	13091	-0.014	-0.5094	No
43	NDUFA6	12473	13358	-0.016	-0.5231	No
44	NDUFC2	18183	13937	-0.022	-0.5534	No
45	PRKCA	20174	14043	-0.023	-0.5581	No
46	GLP1R	23304	14184	-0.025	-0.5646	No
47	PFKFB2	4116 5242	14189	-0.025	-0.5637	No
48	KCNJ11	17822	14369	-0.028	-0.5722	No
49	ATP5C1	8635	14712	-0.034	-0.5892	No
50	CYCS	8821	15080	-0.043	-0.6072	No
51	NDUFAB1	7667	15325	-0.050	-0.6183	No
52	CS	19839	15329	-0.050	-0.6163	No
53	COX7B	7260	15412	-0.053	-0.6185	No
54	NDUFB5	12277	15499	-0.056	-0.6207	No
55	ABCC8	9941 11649	15547	-0.059	-0.6207	No
56	ETFB	18279	15608	-0.061	-0.6214	No
57	ATP5I	8637	16085	-0.084	-0.6435	No
58	ATP5O	22539	16280	-0.097	-0.6498	No
59	ETFDH	15313	16292	-0.098	-0.6462	No
60	COX5A	19431	16365	-0.103	-0.6457	No
61	NDUFB2	7542	16542	-0.116	-0.6503	Yes
62	COX6A1	8774 4553	16575	-0.120	-0.6469	Yes
63	DLAT	19123	16622	-0.124	-0.6441	Yes
64	NDUFB7	12429	16629	-0.125	-0.6391	Yes
65	NDUFS8	23950	16650	-0.127	-0.6348	Yes
66	COX5B	4552	16733	-0.134	-0.6335	Yes
67	ATP5E	14321	16764	-0.137	-0.6293	Yes
68	CYC1	12348	16847	-0.148	-0.6274	Yes
69	ATP5F1	15212	16941	-0.158	-0.6257	Yes
70	NDUFS5	9296	16976	-0.162	-0.6206	Yes
71	NDUFB8	7418	17006	-0.165	-0.6151	Yes
72	UQCRH	12378	17031	-0.168	-0.6092	Yes
73	NDUFA1	24170	17049	-0.170	-0.6029	Yes
74	COX7C	8776	17098	-0.174	-0.5981	Yes
75	NDUFS2	4089 13760	17185	-0.184	-0.5949	Yes
76	COX6B1	4283 8479	17188	-0.184	-0.5872	Yes
77	ATP5G1	8636	17192	-0.184	-0.5795	Yes
78	NDUFA4	9451	17294	-0.197	-0.5765	Yes
79	ATP5J2	12186	17301	-0.198	-0.5684	Yes
80	UQCRC2	18102	17307	-0.198	-0.5602	Yes
81	PDHA1	24020	17331	-0.200	-0.5529	Yes
82	IDH3A	19447	17370	-0.206	-0.5462	Yes
83	NDUFA8	14605	17442	-0.216	-0.5408	Yes
84	NDUFA2	9450	17556	-0.232	-0.5370	Yes
85	NDUFS4	9452 5157 3173	17574	-0.235	-0.5279	Yes
86	NDUFB3	12362	17582	-0.236	-0.5182	Yes
87	UQCR	12382	17638	-0.244	-0.5108	Yes
88	NDUFV1	23953	17746	-0.263	-0.5054	Yes
89	NDUFA9	12288	17800	-0.276	-0.4965	Yes
90	ATP5H	12948	17815	-0.279	-0.4853	Yes
91	COX4I1	18444	17830	-0.281	-0.4741	Yes
92	NDUFA11	12832	17879	-0.294	-0.4642	Yes
93	NDUFA7	12347	17938	-0.308	-0.4542	Yes
94	COX6C	8775	18006	-0.326	-0.4439	Yes
95	TPI1	5795 10212	18147	-0.387	-0.4349	Yes
96	MARCKS	9331	18173	-0.404	-0.4191	Yes
97	DLD	2097 21090	18373	-0.571	-0.4055	Yes
98	NDUFS3	7553 12683	18471	-0.850	-0.3745	Yes
99	ATP5J	880 22555	18553	-1.407	-0.3189	Yes
100	SUCLG1	17409 1059	18574	-1.757	-0.2450	Yes
101	NDUFC1	7287 12339	18616	-5.799	-0.0000	Yes