Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | HYDROLASE_ACTIVITY__ACTING_ON_ESTER_BONDS |
Enrichment Score (ES) | -0.6324369 |
Normalized Enrichment Score (NES) | -1.5666599 |
Nominal p-value | 0.0 |
FDR q-value | 0.7159223 |
FWER p-Value | 0.994 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTP4A3 | 22460 2304 | 361 | 0.400 | -0.0005 | No | ||
2 | POP1 | 2214 7482 | 374 | 0.383 | 0.0171 | No | ||
3 | MBD4 | 17033 | 420 | 0.358 | 0.0318 | No | ||
4 | PTPN6 | 17002 | 451 | 0.338 | 0.0463 | No | ||
5 | HAGH | 9020 | 1035 | 0.169 | 0.0227 | No | ||
6 | PDE1B | 9542 | 1049 | 0.166 | 0.0300 | No | ||
7 | PDE4B | 9543 | 1057 | 0.166 | 0.0375 | No | ||
8 | MTMR3 | 7908 13193 | 1346 | 0.126 | 0.0279 | No | ||
9 | NT5C2 | 3768 8052 | 1363 | 0.125 | 0.0330 | No | ||
10 | PLA2G4B | 14896 | 1658 | 0.096 | 0.0216 | No | ||
11 | PLD3 | 17917 | 1715 | 0.092 | 0.0229 | No | ||
12 | DBR1 | 19341 | 1757 | 0.089 | 0.0249 | No | ||
13 | RNASEH1 | 21302 | 1782 | 0.087 | 0.0278 | No | ||
14 | ISG20 | 18210 | 1847 | 0.083 | 0.0283 | No | ||
15 | USP21 | 13762 | 1996 | 0.072 | 0.0237 | No | ||
16 | LYPLA3 | 18482 | 2119 | 0.064 | 0.0201 | No | ||
17 | ARSA | 4416 | 2278 | 0.057 | 0.0142 | No | ||
18 | POP4 | 7261 | 2370 | 0.053 | 0.0118 | No | ||
19 | GALNS | 11945 | 2437 | 0.050 | 0.0106 | No | ||
20 | WRN | 5882 10315 | 2483 | 0.048 | 0.0104 | No | ||
21 | OTUB2 | 7537 12654 | 2518 | 0.046 | 0.0108 | No | ||
22 | ACP2 | 4318 | 2582 | 0.044 | 0.0095 | No | ||
23 | PTPRM | 22904 | 2586 | 0.044 | 0.0114 | No | ||
24 | N4BP2 | 16837 | 2621 | 0.043 | 0.0116 | No | ||
25 | PDE4C | 8481 | 2729 | 0.039 | 0.0076 | No | ||
26 | APTX | 2455 7291 | 2870 | 0.035 | 0.0017 | No | ||
27 | CTDP1 | 23399 1969 | 2898 | 0.034 | 0.0018 | No | ||
28 | RPP38 | 14698 | 2922 | 0.033 | 0.0022 | No | ||
29 | PTPRO | 1093 17256 | 2988 | 0.032 | 0.0002 | No | ||
30 | AOAH | 11296 | 2993 | 0.032 | 0.0015 | No | ||
31 | DFFA | 4627 | 3134 | 0.029 | -0.0048 | No | ||
32 | PTPLA | 11403 6636 14680 | 3202 | 0.027 | -0.0071 | No | ||
33 | PTEN | 5305 | 3348 | 0.025 | -0.0138 | No | ||
34 | PRDX6 | 4389 8596 | 3356 | 0.024 | -0.0130 | No | ||
35 | DUSP7 | 10661 | 3370 | 0.024 | -0.0126 | No | ||
36 | MAP1S | 11279 | 3524 | 0.022 | -0.0199 | No | ||
37 | PTPRA | 14844 | 3529 | 0.022 | -0.0190 | No | ||
38 | DNASE1L1 | 24128 | 3540 | 0.022 | -0.0185 | No | ||
39 | NT5E | 19360 18702 | 3579 | 0.021 | -0.0196 | No | ||
40 | FEN1 | 8961 | 3629 | 0.020 | -0.0213 | No | ||
41 | PTPN1 | 5325 | 3741 | 0.019 | -0.0264 | No | ||
42 | PTPN5 | 17817 | 3758 | 0.019 | -0.0264 | No | ||
43 | PTP4A2 | 9659 2463 2518 5324 | 3787 | 0.018 | -0.0270 | No | ||
44 | PTPRS | 1507 1565 1602 22928 | 3794 | 0.018 | -0.0265 | No | ||
45 | PDE4A | 3037 19542 3083 3023 | 3810 | 0.018 | -0.0264 | No | ||
46 | INPP4B | 18557 | 3959 | 0.017 | -0.0337 | No | ||
47 | PDE7B | 19807 | 3963 | 0.017 | -0.0331 | No | ||
48 | PTPRD | 11554 5330 | 3979 | 0.016 | -0.0331 | No | ||
49 | PTPN21 | 21009 | 4119 | 0.015 | -0.0399 | No | ||
50 | PNLIPRP1 | 23835 | 4242 | 0.014 | -0.0459 | No | ||
51 | PLA2G2E | 16016 | 4246 | 0.014 | -0.0454 | No | ||
52 | PTPN7 | 11500 | 4274 | 0.014 | -0.0462 | No | ||
53 | PPP1R3C | 23688 | 4383 | 0.013 | -0.0514 | No | ||
54 | ACHE | 16665 | 4467 | 0.013 | -0.0554 | No | ||
55 | ARSB | 4415 439 | 4508 | 0.012 | -0.0569 | No | ||
56 | LPL | 9283 5003 | 4683 | 0.011 | -0.0659 | No | ||
57 | ENPP2 | 9548 | 5042 | 0.010 | -0.0849 | No | ||
58 | DUSP4 | 18632 3820 | 5049 | 0.010 | -0.0848 | No | ||
59 | DUSP8 | 9493 | 5235 | 0.009 | -0.0944 | No | ||
60 | SMPD1 | 18145 2658 | 5308 | 0.009 | -0.0979 | No | ||
61 | CES2 | 18505 | 5309 | 0.009 | -0.0975 | No | ||
62 | PTPRK | 5332 20066 | 5363 | 0.008 | -0.1000 | No | ||
63 | XRN2 | 2936 6302 2905 | 5469 | 0.008 | -0.1053 | No | ||
64 | ERN2 | 17651 | 5518 | 0.008 | -0.1076 | No | ||
65 | PTPRU | 15738 | 5648 | 0.007 | -0.1142 | No | ||
66 | DUSP13 | 21904 | 5884 | 0.007 | -0.1267 | No | ||
67 | BDKRB2 | 21163 | 5971 | 0.006 | -0.1311 | No | ||
68 | PLD2 | 20803 | 6063 | 0.006 | -0.1357 | No | ||
69 | PTPN2 | 23414 | 6127 | 0.006 | -0.1389 | No | ||
70 | RAD9A | 913 3674 910 23958 | 6169 | 0.006 | -0.1408 | No | ||
71 | TPTE | 3875 3866 10615 3777 | 6338 | 0.005 | -0.1497 | No | ||
72 | MTMR2 | 8069 3003 | 6517 | 0.005 | -0.1592 | No | ||
73 | CCKBR | 8706 | 6640 | 0.004 | -0.1656 | No | ||
74 | EDNRA | 18834 | 6646 | 0.004 | -0.1657 | No | ||
75 | PLCD1 | 18972 | 6690 | 0.004 | -0.1678 | No | ||
76 | PLA2G3 | 20968 | 6695 | 0.004 | -0.1678 | No | ||
77 | PDE1C | 5235 | 6716 | 0.004 | -0.1687 | No | ||
78 | PDE10A | 23387 | 6970 | 0.004 | -0.1823 | No | ||
79 | PTPRH | 11861 | 7093 | 0.004 | -0.1887 | No | ||
80 | PLA2G1B | 9581 | 7138 | 0.003 | -0.1910 | No | ||
81 | PLA1A | 1737 22594 | 7160 | 0.003 | -0.1920 | No | ||
82 | PTPRJ | 9664 | 7224 | 0.003 | -0.1952 | No | ||
83 | LYPLA1 | 4107 9580 | 7225 | 0.003 | -0.1951 | No | ||
84 | ACP1 | 4317 | 7377 | 0.003 | -0.2031 | No | ||
85 | AADAC | 15584 | 7433 | 0.003 | -0.2060 | No | ||
86 | PLA2G2D | 16018 | 7494 | 0.003 | -0.2091 | No | ||
87 | PLA2G2A | 16017 | 7531 | 0.003 | -0.2110 | No | ||
88 | MTMR7 | 12032 | 7678 | 0.002 | -0.2188 | No | ||
89 | CDKN3 | 16965 | 7702 | 0.002 | -0.2199 | No | ||
90 | PNLIP | 23830 | 7732 | 0.002 | -0.2214 | No | ||
91 | MINPP1 | 3663 5100 9389 3748 9388 | 8112 | 0.002 | -0.2419 | No | ||
92 | CES1 | 18789 | 8266 | 0.001 | -0.2502 | No | ||
93 | C3AR1 | 8668 | 8275 | 0.001 | -0.2506 | No | ||
94 | F2RL2 | 21580 | 8456 | 0.001 | -0.2603 | No | ||
95 | PLD1 | 15624 | 8474 | 0.001 | -0.2612 | No | ||
96 | PNPLA3 | 22406 | 8551 | 0.001 | -0.2653 | No | ||
97 | PFKFB1 | 9552 | 8574 | 0.001 | -0.2665 | No | ||
98 | PTPRG | 22097 3151 | 8637 | 0.001 | -0.2698 | No | ||
99 | GNS | 19865 | 8700 | 0.000 | -0.2732 | No | ||
100 | CASR | 22602 | 8753 | 0.000 | -0.2760 | No | ||
101 | RNASE2 | 16758 | 8877 | 0.000 | -0.2827 | No | ||
102 | PLCB2 | 5262 | 8945 | 0.000 | -0.2863 | No | ||
103 | DUSP12 | 13765 | 8990 | -0.000 | -0.2887 | No | ||
104 | PLA2G4C | 147 | 9011 | -0.000 | -0.2898 | No | ||
105 | PNLIPRP2 | 23836 | 9085 | -0.000 | -0.2938 | No | ||
106 | PTPRF | 5331 2545 | 9244 | -0.000 | -0.3023 | No | ||
107 | PTPN4 | 13856 | 9269 | -0.001 | -0.3036 | No | ||
108 | TREX2 | 24137 | 9295 | -0.001 | -0.3049 | No | ||
109 | DNASE2 | 8855 | 9429 | -0.001 | -0.3121 | No | ||
110 | DUSP3 | 1358 13022 | 9566 | -0.001 | -0.3195 | No | ||
111 | PTPN3 | 9661 | 9747 | -0.001 | -0.3292 | No | ||
112 | USP29 | 18398 | 10031 | -0.002 | -0.3445 | No | ||
113 | PPEF2 | 16481 | 10287 | -0.002 | -0.3583 | No | ||
114 | PPP2R2A | 3222 21774 | 10346 | -0.002 | -0.3614 | No | ||
115 | OGG1 | 17331 | 10356 | -0.002 | -0.3617 | No | ||
116 | PTPN11 | 5326 16391 9660 | 10593 | -0.003 | -0.3745 | No | ||
117 | PLCE1 | 13156 | 10690 | -0.003 | -0.3795 | No | ||
118 | PSPH | 16362 | 10800 | -0.003 | -0.3853 | No | ||
119 | CHRM5 | 10038 | 10804 | -0.003 | -0.3853 | No | ||
120 | NANP | 12511 | 10812 | -0.003 | -0.3856 | No | ||
121 | POP7 | 16329 | 10879 | -0.003 | -0.3890 | No | ||
122 | TREX1 | 10219 3111 | 11032 | -0.004 | -0.3971 | No | ||
123 | SULF1 | 6285 | 11182 | -0.004 | -0.4050 | No | ||
124 | PTPN12 | 16597 3502 3586 3665 | 11440 | -0.004 | -0.4188 | No | ||
125 | USP12 | 5825 5824 | 11532 | -0.005 | -0.4235 | No | ||
126 | PTPRR | 3436 19876 | 11540 | -0.005 | -0.4237 | No | ||
127 | PTPRT | 5333 | 11600 | -0.005 | -0.4267 | No | ||
128 | CHRM1 | 23943 | 11616 | -0.005 | -0.4272 | No | ||
129 | DFFB | 15654 | 11654 | -0.005 | -0.4290 | No | ||
130 | HIBCH | 14250 | 11754 | -0.005 | -0.4342 | No | ||
131 | USP5 | 17004 | 11803 | -0.005 | -0.4365 | No | ||
132 | PTPRN | 13914 | 11858 | -0.005 | -0.4392 | No | ||
133 | LIPG | 23407 | 11878 | -0.005 | -0.4400 | No | ||
134 | ACP5 | 19200 | 12077 | -0.006 | -0.4505 | No | ||
135 | DLG1 | 22793 1672 | 12209 | -0.006 | -0.4573 | No | ||
136 | CILP | 19404 | 12297 | -0.006 | -0.4617 | No | ||
137 | ACOT9 | 24221 | 12392 | -0.007 | -0.4665 | No | ||
138 | EXOSC7 | 19256 | 12395 | -0.007 | -0.4663 | No | ||
139 | PTPRB | 19875 | 12465 | -0.007 | -0.4697 | No | ||
140 | UCHL3 | 6956 | 12479 | -0.007 | -0.4701 | No | ||
141 | SMPD2 | 5462 | 12628 | -0.007 | -0.4778 | No | ||
142 | PTPRN2 | 9666 | 12723 | -0.008 | -0.4826 | No | ||
143 | ACOT12 | 21591 | 12810 | -0.008 | -0.4869 | No | ||
144 | DNASE1L2 | 960 23092 | 12918 | -0.008 | -0.4923 | No | ||
145 | CCR5 | 8754 4534 | 12991 | -0.008 | -0.4958 | No | ||
146 | PTPN14 | 14012 | 13118 | -0.009 | -0.5022 | No | ||
147 | EPM2A | 20090 | 13171 | -0.009 | -0.5046 | No | ||
148 | ENPP3 | 19803 | 13516 | -0.011 | -0.5228 | No | ||
149 | PDE1A | 9541 5234 | 13627 | -0.011 | -0.5283 | No | ||
150 | STS | 5542 | 13638 | -0.011 | -0.5283 | No | ||
151 | LCK | 15746 | 13697 | -0.012 | -0.5309 | No | ||
152 | PPAP2B | 7503 16161 | 13761 | -0.012 | -0.5337 | No | ||
153 | RAD50 | 1198 20460 | 13993 | -0.014 | -0.5456 | No | ||
154 | PLA2G5 | 9583 | 14152 | -0.015 | -0.5535 | No | ||
155 | PDE3A | 7045 | 14193 | -0.015 | -0.5550 | No | ||
156 | MGLL | 17368 1145 | 14312 | -0.016 | -0.5606 | No | ||
157 | DUSP2 | 14865 | 14352 | -0.016 | -0.5620 | No | ||
158 | PPAP2C | 6938 | 14360 | -0.016 | -0.5616 | No | ||
159 | ACOT11 | 2432 6836 | 14522 | -0.018 | -0.5695 | No | ||
160 | PTPN18 | 14279 | 14538 | -0.018 | -0.5695 | No | ||
161 | LIPE | 17927 | 14544 | -0.018 | -0.5689 | No | ||
162 | ERCC4 | 6927 11921 | 14623 | -0.018 | -0.5723 | No | ||
163 | PLA2G10 | 22658 | 14631 | -0.019 | -0.5718 | No | ||
164 | RPP40 | 21491 | 14672 | -0.019 | -0.5730 | No | ||
165 | PPAP2A | 21562 3258 3244 | 14750 | -0.020 | -0.5763 | No | ||
166 | IMPA1 | 12066 | 14833 | -0.021 | -0.5798 | No | ||
167 | LIPF | 23883 | 14872 | -0.021 | -0.5808 | No | ||
168 | USP53 | 5245 8283 | 14960 | -0.022 | -0.5845 | No | ||
169 | PDE4D | 10722 6235 | 14994 | -0.023 | -0.5852 | No | ||
170 | IDS | 9142 2617 | 15002 | -0.023 | -0.5845 | No | ||
171 | RNASE1 | 21845 | 15041 | -0.024 | -0.5854 | No | ||
172 | PPP2CB | 18636 | 15065 | -0.024 | -0.5855 | No | ||
173 | PTPN9 | 19434 | 15168 | -0.025 | -0.5899 | No | ||
174 | FBP2 | 21422 | 15262 | -0.027 | -0.5936 | No | ||
175 | EXO1 | 14035 4135 | 15296 | -0.027 | -0.5941 | No | ||
176 | CHRM3 | 21547 | 15318 | -0.028 | -0.5939 | No | ||
177 | SBF1 | 13420 | 15322 | -0.028 | -0.5927 | No | ||
178 | INPP5E | 14650 | 15448 | -0.031 | -0.5981 | No | ||
179 | APOC2 | 8616 | 15456 | -0.031 | -0.5970 | No | ||
180 | MIR16 | 17663 1354 | 15520 | -0.033 | -0.5989 | No | ||
181 | PPP1CA | 9608 3756 914 909 | 15541 | -0.033 | -0.5984 | No | ||
182 | PTPRC | 5327 9662 | 15675 | -0.036 | -0.6039 | No | ||
183 | G6PC | 20656 | 15895 | -0.043 | -0.6137 | No | ||
184 | NT5C | 20151 | 16035 | -0.048 | -0.6190 | No | ||
185 | RPP30 | 23877 | 16166 | -0.054 | -0.6235 | No | ||
186 | CDC14B | 3227 5750 | 16253 | -0.058 | -0.6254 | No | ||
187 | MRE11A | 3014 19560 | 16341 | -0.062 | -0.6272 | No | ||
188 | DULLARD | 20816 | 16390 | -0.064 | -0.6267 | No | ||
189 | PPP5C | 17952 | 16397 | -0.064 | -0.6240 | No | ||
190 | PTPRE | 1662 18039 | 16554 | -0.072 | -0.6290 | Yes | ||
191 | PDE7A | 9544 1788 | 16615 | -0.076 | -0.6286 | Yes | ||
192 | PPM1A | 5279 9607 | 16658 | -0.078 | -0.6272 | Yes | ||
193 | DUSP11 | 17086 7785 | 16746 | -0.086 | -0.6278 | Yes | ||
194 | PPP6C | 7491 | 16789 | -0.089 | -0.6258 | Yes | ||
195 | PLA2G6 | 22209 | 16809 | -0.090 | -0.6225 | Yes | ||
196 | NT5C3 | 17136 | 16899 | -0.096 | -0.6228 | Yes | ||
197 | SULF2 | 12988 | 16909 | -0.097 | -0.6186 | Yes | ||
198 | PDE2A | 18170 | 16916 | -0.097 | -0.6143 | Yes | ||
199 | PPM1D | 20721 | 16933 | -0.098 | -0.6105 | Yes | ||
200 | RAD1 | 22507 | 16953 | -0.100 | -0.6067 | Yes | ||
201 | NTHL1 | 23357 | 17045 | -0.108 | -0.6066 | Yes | ||
202 | CYCS | 8821 | 17067 | -0.110 | -0.6025 | Yes | ||
203 | DICER1 | 20989 | 17140 | -0.116 | -0.6008 | Yes | ||
204 | ACP6 | 12394 | 17162 | -0.118 | -0.5963 | Yes | ||
205 | DNASE1L3 | 21925 | 17234 | -0.126 | -0.5941 | Yes | ||
206 | PDE3B | 5236 | 17283 | -0.132 | -0.5904 | Yes | ||
207 | PPM1G | 16571 | 17383 | -0.143 | -0.5890 | Yes | ||
208 | PPP1R8 | 15730 | 17414 | -0.145 | -0.5837 | Yes | ||
209 | INPP5D | 14198 | 17426 | -0.146 | -0.5773 | Yes | ||
210 | RNASEH2A | 12819 | 17458 | -0.149 | -0.5719 | Yes | ||
211 | CNP | 8760 | 17479 | -0.151 | -0.5658 | Yes | ||
212 | BPNT1 | 4082 14015 | 17484 | -0.151 | -0.5588 | Yes | ||
213 | EXOSC2 | 15044 | 17684 | -0.178 | -0.5611 | Yes | ||
214 | PON2 | 11637 | 17694 | -0.179 | -0.5530 | Yes | ||
215 | IMPA2 | 4328 | 17853 | -0.203 | -0.5519 | Yes | ||
216 | PDIA3 | 14888 | 17913 | -0.216 | -0.5447 | Yes | ||
217 | FBP1 | 21423 | 17975 | -0.232 | -0.5370 | Yes | ||
218 | CDC25B | 14841 | 17982 | -0.234 | -0.5261 | Yes | ||
219 | ERCC5 | 14255 4097 | 17987 | -0.236 | -0.5150 | Yes | ||
220 | RNASE6 | 13439 | 17990 | -0.237 | -0.5038 | Yes | ||
221 | TIMM50 | 17911 | 18035 | -0.251 | -0.4942 | Yes | ||
222 | DLG7 | 21858 | 18079 | -0.267 | -0.4838 | Yes | ||
223 | NME1 | 9467 | 18100 | -0.274 | -0.4717 | Yes | ||
224 | INPP1 | 13961 | 18109 | -0.276 | -0.4590 | Yes | ||
225 | DUSP1 | 23061 | 18286 | -0.382 | -0.4503 | Yes | ||
226 | UCHL1 | 16834 | 18321 | -0.409 | -0.4326 | Yes | ||
227 | ACOT8 | 14344 2749 | 18330 | -0.416 | -0.4131 | Yes | ||
228 | ERCC1 | 1235 1045 1646 | 18410 | -0.535 | -0.3919 | Yes | ||
229 | PPT1 | 9613 | 18419 | -0.563 | -0.3654 | Yes | ||
230 | PNKP | 4052 18258 | 18427 | -0.587 | -0.3377 | Yes | ||
231 | APEX1 | 22028 | 18437 | -0.619 | -0.3086 | Yes | ||
232 | PPM1B | 5280 1567 5281 | 18524 | -1.218 | -0.2550 | Yes | ||
233 | DUSP6 | 19891 3399 | 18525 | -1.221 | -0.1966 | Yes | ||
234 | TP53 | 20822 | 18592 | -2.086 | -0.1004 | Yes | ||
235 | PTPN22 | 1775 15470 | 18593 | -2.127 | 0.0013 | Yes |