Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | DMproB |
GeneSet | EXTRACELLULAR_SPACE |
Enrichment Score (ES) | 0.65471053 |
Normalized Enrichment Score (NES) | 1.545505 |
Nominal p-value | 0.0 |
FDR q-value | 0.44077498 |
FWER p-Value | 0.999 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MMP9 | 14732 | 39 | 1.877 | 0.1396 | Yes | ||
2 | CHI3L1 | 14131 | 96 | 1.302 | 0.2349 | Yes | ||
3 | EBI3 | 23193 | 109 | 1.238 | 0.3277 | Yes | ||
4 | TGFBI | 3181 21622 | 162 | 0.812 | 0.3862 | Yes | ||
5 | CFP | 24174 | 199 | 0.656 | 0.4338 | Yes | ||
6 | GPC1 | 4796 | 208 | 0.627 | 0.4807 | Yes | ||
7 | IL1B | 14431 | 316 | 0.447 | 0.5086 | Yes | ||
8 | VEGFA | 22969 | 400 | 0.372 | 0.5322 | Yes | ||
9 | PSAP | 20014 | 589 | 0.275 | 0.5428 | Yes | ||
10 | SLIT1 | 23678 | 613 | 0.268 | 0.5617 | Yes | ||
11 | IL12A | 4913 | 632 | 0.261 | 0.5804 | Yes | ||
12 | LBP | 14760 | 665 | 0.249 | 0.5975 | Yes | ||
13 | IL16 | 9171 | 726 | 0.230 | 0.6117 | Yes | ||
14 | ORM1 | 9516 | 792 | 0.213 | 0.6242 | Yes | ||
15 | FXYD6 | 19471 | 901 | 0.191 | 0.6328 | Yes | ||
16 | ADM | 18125 | 961 | 0.181 | 0.6433 | Yes | ||
17 | FJX1 | 4725 | 1015 | 0.172 | 0.6534 | Yes | ||
18 | PGCP | 12030 | 1381 | 0.122 | 0.6429 | Yes | ||
19 | HDGF | 9082 4846 4845 | 1488 | 0.112 | 0.6455 | Yes | ||
20 | GPX3 | 20880 | 1499 | 0.111 | 0.6534 | Yes | ||
21 | C1QB | 8667 | 1672 | 0.095 | 0.6512 | Yes | ||
22 | IL9R | 20505 | 1734 | 0.090 | 0.6547 | Yes | ||
23 | SDF2 | 20762 | 2163 | 0.062 | 0.6362 | No | ||
24 | FGL2 | 16911 | 2309 | 0.055 | 0.6325 | No | ||
25 | MMP8 | 19570 | 2389 | 0.052 | 0.6321 | No | ||
26 | FLT1 | 3483 16287 | 2465 | 0.049 | 0.6317 | No | ||
27 | CTRL | 18760 | 2792 | 0.037 | 0.6168 | No | ||
28 | FSTL1 | 22765 | 2937 | 0.033 | 0.6115 | No | ||
29 | FBN1 | 14449 | 3013 | 0.031 | 0.6098 | No | ||
30 | FSTL3 | 19961 | 3103 | 0.029 | 0.6072 | No | ||
31 | FGF2 | 15608 | 3330 | 0.025 | 0.5968 | No | ||
32 | CXCL9 | 5099 | 3394 | 0.024 | 0.5952 | No | ||
33 | PTN | 5323 | 3468 | 0.023 | 0.5929 | No | ||
34 | SCRG1 | 18614 | 3603 | 0.021 | 0.5872 | No | ||
35 | MMP10 | 19571 | 3631 | 0.020 | 0.5873 | No | ||
36 | LCAT | 18762 | 3889 | 0.017 | 0.5746 | No | ||
37 | NOG | 13663 | 4054 | 0.016 | 0.5669 | No | ||
38 | MMP13 | 19573 3007 | 4141 | 0.015 | 0.5634 | No | ||
39 | C2 | 23013 | 4215 | 0.014 | 0.5605 | No | ||
40 | WNT2B | 15214 1838 | 4286 | 0.014 | 0.5577 | No | ||
41 | FGL1 | 18891 | 4308 | 0.014 | 0.5576 | No | ||
42 | GREM1 | 14485 | 4322 | 0.013 | 0.5579 | No | ||
43 | CPB2 | 21958 2894 3525 | 4540 | 0.012 | 0.5471 | No | ||
44 | IL27 | 17636 | 4558 | 0.012 | 0.5471 | No | ||
45 | PLG | 1593 23383 | 4689 | 0.011 | 0.5409 | No | ||
46 | FGFBP1 | 8967 | 5005 | 0.010 | 0.5245 | No | ||
47 | CXCL2 | 9790 | 5096 | 0.009 | 0.5203 | No | ||
48 | REG3A | 17406 | 5468 | 0.008 | 0.5008 | No | ||
49 | CRISP2 | 22979 | 5527 | 0.008 | 0.4982 | No | ||
50 | IGFALS | 9158 | 5615 | 0.007 | 0.4941 | No | ||
51 | SECTM1 | 20104 | 5628 | 0.007 | 0.4940 | No | ||
52 | SFN | 7060 12062 | 5663 | 0.007 | 0.4927 | No | ||
53 | SHH | 16581 | 5739 | 0.007 | 0.4891 | No | ||
54 | EREG | 4679 16797 | 5847 | 0.007 | 0.4838 | No | ||
55 | INHA | 14214 | 5901 | 0.007 | 0.4815 | No | ||
56 | CCL22 | 18518 | 5954 | 0.006 | 0.4791 | No | ||
57 | IGFBP1 | 20948 | 6263 | 0.005 | 0.4628 | No | ||
58 | ANGPTL1 | 10195 8589 13064 | 6264 | 0.005 | 0.4632 | No | ||
59 | HYAL1 | 9139 | 6357 | 0.005 | 0.4586 | No | ||
60 | MEP1B | 23612 5093 | 6386 | 0.005 | 0.4575 | No | ||
61 | TAC1 | 17526 19853 | 6612 | 0.005 | 0.4456 | No | ||
62 | YARS | 16071 | 6621 | 0.005 | 0.4455 | No | ||
63 | FBLN1 | 4716 2208 | 6671 | 0.004 | 0.4432 | No | ||
64 | PLA2G3 | 20968 | 6695 | 0.004 | 0.4423 | No | ||
65 | CDH13 | 4506 3826 | 6712 | 0.004 | 0.4417 | No | ||
66 | AMH | 19939 | 6788 | 0.004 | 0.4380 | No | ||
67 | LALBA | 22141 | 6808 | 0.004 | 0.4373 | No | ||
68 | DKK3 | 17673 2361 | 6873 | 0.004 | 0.4341 | No | ||
69 | CPA1 | 17496 | 6915 | 0.004 | 0.4321 | No | ||
70 | EPO | 8911 | 6982 | 0.004 | 0.4288 | No | ||
71 | CCL4 | 1362 20730 | 6988 | 0.004 | 0.4289 | No | ||
72 | KLK8 | 18269 18271 | 7025 | 0.004 | 0.4272 | No | ||
73 | SFRP1 | 9805 | 7061 | 0.004 | 0.4256 | No | ||
74 | SEMA3E | 16918 | 7064 | 0.004 | 0.4257 | No | ||
75 | MYOC | 9440 14079 | 7176 | 0.003 | 0.4199 | No | ||
76 | APCS | 13748 | 7265 | 0.003 | 0.4154 | No | ||
77 | CRLF1 | 18588 | 7421 | 0.003 | 0.4072 | No | ||
78 | ORM2 | 16193 | 7532 | 0.003 | 0.4014 | No | ||
79 | GRP | 23531 | 7717 | 0.002 | 0.3916 | No | ||
80 | TPT1 | 5799 | 7741 | 0.002 | 0.3905 | No | ||
81 | CXCL1 | 9044 | 7806 | 0.002 | 0.3872 | No | ||
82 | SCUBE1 | 7231 | 7831 | 0.002 | 0.3861 | No | ||
83 | CRISP1 | 22980 | 7907 | 0.002 | 0.3822 | No | ||
84 | NUCB2 | 18114 | 7983 | 0.002 | 0.3782 | No | ||
85 | CLCA3 | 6224 | 8152 | 0.001 | 0.3692 | No | ||
86 | SFRP4 | 9806 | 8315 | 0.001 | 0.3605 | No | ||
87 | CCL2 | 9788 | 8530 | 0.001 | 0.3490 | No | ||
88 | LGALS7 | 4992 | 8576 | 0.001 | 0.3466 | No | ||
89 | NPY | 17449 | 8670 | 0.001 | 0.3416 | No | ||
90 | IL6 | 16895 | 8787 | 0.000 | 0.3353 | No | ||
91 | KL | 16611 | 9220 | -0.000 | 0.3119 | No | ||
92 | SFRP5 | 23674 | 9303 | -0.001 | 0.3075 | No | ||
93 | PTHLH | 16931 | 9355 | -0.001 | 0.3047 | No | ||
94 | IL17C | 18438 | 9521 | -0.001 | 0.2959 | No | ||
95 | IL1RN | 15096 | 9650 | -0.001 | 0.2890 | No | ||
96 | IL12B | 20918 | 9681 | -0.001 | 0.2875 | No | ||
97 | EDN1 | 21658 | 9812 | -0.001 | 0.2805 | No | ||
98 | WFDC12 | 14356 | 9869 | -0.001 | 0.2776 | No | ||
99 | FGB | 15309 | 10044 | -0.002 | 0.2683 | No | ||
100 | AMY2A | 8587 | 10118 | -0.002 | 0.2644 | No | ||
101 | VTN | 20756 | 10167 | -0.002 | 0.2620 | No | ||
102 | MEP1A | 22974 | 10228 | -0.002 | 0.2589 | No | ||
103 | WNT5A | 22066 5880 | 10268 | -0.002 | 0.2569 | No | ||
104 | MMP3 | 19572 3148 | 10517 | -0.003 | 0.2436 | No | ||
105 | FGF12 | 1723 22621 | 10769 | -0.003 | 0.2303 | No | ||
106 | SERPINA7 | 6856 | 10778 | -0.003 | 0.2301 | No | ||
107 | HBEGF | 23457 | 10798 | -0.003 | 0.2293 | No | ||
108 | MMP20 | 19569 | 10828 | -0.003 | 0.2279 | No | ||
109 | DKK2 | 15418 | 10866 | -0.003 | 0.2262 | No | ||
110 | MSMB | 22053 | 11048 | -0.004 | 0.2166 | No | ||
111 | IL4 | 9174 | 11369 | -0.004 | 0.1996 | No | ||
112 | IL5 | 20884 10220 | 11453 | -0.004 | 0.1954 | No | ||
113 | IL13RA2 | 24036 | 11524 | -0.005 | 0.1919 | No | ||
114 | APOD | 22614 | 11622 | -0.005 | 0.1870 | No | ||
115 | LEP | 17505 | 11692 | -0.005 | 0.1837 | No | ||
116 | PRSS8 | 17606 | 11951 | -0.006 | 0.1701 | No | ||
117 | PRSS2 | 17474 | 11982 | -0.006 | 0.1689 | No | ||
118 | MMP7 | 19568 | 12018 | -0.006 | 0.1674 | No | ||
119 | ANGPTL3 | 16171 | 12107 | -0.006 | 0.1631 | No | ||
120 | CFH | 4515 13813 13814 | 12181 | -0.006 | 0.1596 | No | ||
121 | LGALS8 | 21544 | 12224 | -0.006 | 0.1578 | No | ||
122 | COL25A1 | 8056 1837 1844 1915 13376 | 12271 | -0.006 | 0.1558 | No | ||
123 | IL1A | 4915 | 12286 | -0.006 | 0.1555 | No | ||
124 | SST | 22625 | 12318 | -0.006 | 0.1543 | No | ||
125 | ANGPTL2 | 15032 18104 | 12363 | -0.007 | 0.1524 | No | ||
126 | IL3 | 20453 | 12431 | -0.007 | 0.1493 | No | ||
127 | APOA5 | 19469 | 12493 | -0.007 | 0.1465 | No | ||
128 | FGF5 | 16785 | 12521 | -0.007 | 0.1456 | No | ||
129 | EGFL6 | 24006 | 12595 | -0.007 | 0.1422 | No | ||
130 | LECT2 | 21443 | 12707 | -0.008 | 0.1367 | No | ||
131 | GHRL | 1183 17040 | 12733 | -0.008 | 0.1359 | No | ||
132 | SLIT3 | 20925 | 12761 | -0.008 | 0.1350 | No | ||
133 | ANGPT2 | 14885 3783 18923 | 12795 | -0.008 | 0.1338 | No | ||
134 | HTRA1 | 18051 | 12825 | -0.008 | 0.1329 | No | ||
135 | PCSK5 | 23714 | 12847 | -0.008 | 0.1323 | No | ||
136 | SOD1 | 9846 | 12914 | -0.008 | 0.1294 | No | ||
137 | SCG2 | 5410 14425 | 12945 | -0.008 | 0.1284 | No | ||
138 | PCSK9 | 15822 | 13029 | -0.009 | 0.1245 | No | ||
139 | FGG | 1891 | 13031 | -0.009 | 0.1251 | No | ||
140 | C1QA | 8666 | 13039 | -0.009 | 0.1254 | No | ||
141 | FGF9 | 8966 | 13102 | -0.009 | 0.1227 | No | ||
142 | FGF17 | 21757 | 13149 | -0.009 | 0.1209 | No | ||
143 | IL15 | 18826 3801 | 13227 | -0.009 | 0.1174 | No | ||
144 | CCL1 | 9787 | 13240 | -0.009 | 0.1175 | No | ||
145 | SEMA3F | 18999 3097 | 13291 | -0.010 | 0.1155 | No | ||
146 | CALCA | 4470 | 13383 | -0.010 | 0.1113 | No | ||
147 | ATRN | 4432 2964 | 13448 | -0.010 | 0.1086 | No | ||
148 | RBP4 | 23686 | 13453 | -0.010 | 0.1092 | No | ||
149 | PCSK2 | 9537 5231 14824 | 13479 | -0.011 | 0.1086 | No | ||
150 | PVR | 10020 | 13510 | -0.011 | 0.1078 | No | ||
151 | PGC | 23208 | 13661 | -0.012 | 0.1005 | No | ||
152 | FGF16 | 24270 | 13678 | -0.012 | 0.1006 | No | ||
153 | MBL2 | 23886 | 13768 | -0.012 | 0.0966 | No | ||
154 | CFHR1 | 11926 13815 | 13870 | -0.013 | 0.0921 | No | ||
155 | FGA | 1780 15566 | 14005 | -0.014 | 0.0859 | No | ||
156 | UTS2 | 15985 2520 | 14022 | -0.014 | 0.0861 | No | ||
157 | CSF3 | 1394 20671 | 14163 | -0.015 | 0.0796 | No | ||
158 | AREG | 16796 | 14172 | -0.015 | 0.0803 | No | ||
159 | CP | 4555 | 14405 | -0.017 | 0.0689 | No | ||
160 | CD5L | 15560 | 14485 | -0.017 | 0.0659 | No | ||
161 | LIPE | 17927 | 14544 | -0.018 | 0.0641 | No | ||
162 | CARTPT | 21374 | 14706 | -0.019 | 0.0568 | No | ||
163 | IL5RA | 17051 | 14847 | -0.021 | 0.0508 | No | ||
164 | IK | 23594 | 14898 | -0.022 | 0.0497 | No | ||
165 | FGF10 | 4719 8962 | 14911 | -0.022 | 0.0507 | No | ||
166 | TCN2 | 20550 | 15022 | -0.023 | 0.0465 | No | ||
167 | FGF18 | 4721 1351 | 15078 | -0.024 | 0.0453 | No | ||
168 | CPN1 | 23667 | 15091 | -0.024 | 0.0465 | No | ||
169 | CCL7 | 20743 | 15149 | -0.025 | 0.0453 | No | ||
170 | KLK5 | 1307 9237 | 15166 | -0.025 | 0.0463 | No | ||
171 | MMP2 | 18525 | 15190 | -0.026 | 0.0470 | No | ||
172 | LOXL2 | 8256 | 15206 | -0.026 | 0.0482 | No | ||
173 | HABP2 | 10364 23825 | 15217 | -0.026 | 0.0496 | No | ||
174 | APOA2 | 8615 4044 | 15265 | -0.027 | 0.0491 | No | ||
175 | IL17A | 14289 | 15295 | -0.027 | 0.0496 | No | ||
176 | EFNA5 | 4655 8884 | 15300 | -0.028 | 0.0515 | No | ||
177 | F2 | 14524 | 15366 | -0.029 | 0.0501 | No | ||
178 | PCSK1N | 6624 | 15518 | -0.032 | 0.0444 | No | ||
179 | DLK1 | 4632 | 15524 | -0.033 | 0.0466 | No | ||
180 | FIGF | 24212 | 15828 | -0.041 | 0.0332 | No | ||
181 | C8A | 15823 | 15903 | -0.043 | 0.0324 | No | ||
182 | SPN | 452 5493 | 15930 | -0.044 | 0.0343 | No | ||
183 | TNFAIP2 | 21144 2100 | 15978 | -0.046 | 0.0353 | No | ||
184 | APOA1 | 8614 | 15994 | -0.047 | 0.0380 | No | ||
185 | TGFB1 | 18332 | 16358 | -0.063 | 0.0230 | No | ||
186 | IDE | 4893 | 16976 | -0.102 | -0.0028 | No | ||
187 | SCYE1 | 8897 | 17360 | -0.141 | -0.0129 | No | ||
188 | FVT1 | 13862 | 17505 | -0.154 | -0.0091 | No | ||
189 | LGALS3BP | 20129 | 17519 | -0.157 | 0.0021 | No | ||
190 | MFNG | 2245 22215 | 17647 | -0.174 | 0.0083 | No | ||
191 | COPA | 8773 | 17729 | -0.184 | 0.0178 | No | ||
192 | NUCB1 | 9494 5201 | 18314 | -0.402 | 0.0164 | No |