Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | DMproB |
GeneSet | DEFENSE_RESPONSE |
Enrichment Score (ES) | 0.69095665 |
Normalized Enrichment Score (NES) | 1.6319257 |
Nominal p-value | 0.0 |
FDR q-value | 0.16574295 |
FWER p-Value | 0.573 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CAMP | 18990 | 8 | 3.213 | 0.1064 | Yes | ||
2 | S100A9 | 9774 | 22 | 2.490 | 0.1884 | Yes | ||
3 | PGLYRP1 | 18369 | 27 | 2.300 | 0.2647 | Yes | ||
4 | TNIP1 | 12192 20450 1320 | 35 | 2.016 | 0.3313 | Yes | ||
5 | S100A8 | 15527 | 40 | 1.871 | 0.3933 | Yes | ||
6 | LTB4R | 22003 | 61 | 1.449 | 0.4404 | Yes | ||
7 | CEBPB | 8733 | 151 | 0.910 | 0.4658 | Yes | ||
8 | ITGB1 | 3872 18411 | 188 | 0.692 | 0.4868 | Yes | ||
9 | CFP | 24174 | 199 | 0.656 | 0.5081 | Yes | ||
10 | TYROBP | 18302 | 202 | 0.649 | 0.5296 | Yes | ||
11 | PRDX5 | 7053 3732 | 214 | 0.618 | 0.5495 | Yes | ||
12 | LSP1 | 18003 | 267 | 0.508 | 0.5636 | Yes | ||
13 | RSAD2 | 21094 | 345 | 0.412 | 0.5731 | Yes | ||
14 | ALOX5AP | 16616 | 384 | 0.379 | 0.5836 | Yes | ||
15 | WAS | 24193 | 491 | 0.319 | 0.5885 | Yes | ||
16 | CCR7 | 20254 | 561 | 0.284 | 0.5942 | Yes | ||
17 | CD84 | 14049 | 586 | 0.276 | 0.6020 | Yes | ||
18 | CD48 | 14051 | 592 | 0.274 | 0.6109 | Yes | ||
19 | HDAC7A | 22147 | 607 | 0.270 | 0.6191 | Yes | ||
20 | CD19 | 17640 | 629 | 0.261 | 0.6266 | Yes | ||
21 | IL12A | 4913 | 632 | 0.261 | 0.6352 | Yes | ||
22 | BCL10 | 15397 | 634 | 0.260 | 0.6438 | Yes | ||
23 | LBP | 14760 | 665 | 0.249 | 0.6504 | Yes | ||
24 | TPST1 | 10214 | 706 | 0.236 | 0.6561 | Yes | ||
25 | ANXA1 | 9282 | 752 | 0.223 | 0.6611 | Yes | ||
26 | ORM1 | 9516 | 792 | 0.213 | 0.6660 | Yes | ||
27 | CLEC5A | 6225 | 836 | 0.204 | 0.6705 | Yes | ||
28 | NOD1 | 17141 | 839 | 0.203 | 0.6771 | Yes | ||
29 | ZNF148 | 5949 | 880 | 0.196 | 0.6814 | Yes | ||
30 | KCNN4 | 18353 | 913 | 0.190 | 0.6860 | Yes | ||
31 | NFE2L1 | 9457 | 937 | 0.186 | 0.6910 | Yes | ||
32 | CX3CR1 | 18965 | 1341 | 0.126 | 0.6733 | No | ||
33 | CD81 | 8719 | 1397 | 0.121 | 0.6743 | No | ||
34 | NFRKB | 10642 | 1573 | 0.104 | 0.6682 | No | ||
35 | VEZF1 | 20709 | 1652 | 0.097 | 0.6672 | No | ||
36 | NFKB1 | 15160 | 1685 | 0.094 | 0.6686 | No | ||
37 | BECN1 | 7077 | 1700 | 0.093 | 0.6709 | No | ||
38 | NLRC4 | 11225 | 1760 | 0.089 | 0.6707 | No | ||
39 | NFX1 | 2475 | 1976 | 0.074 | 0.6615 | No | ||
40 | CBARA1 | 20015 | 1992 | 0.073 | 0.6631 | No | ||
41 | CXCR4 | 13844 | 2107 | 0.065 | 0.6590 | No | ||
42 | MEFV | 22686 | 2125 | 0.064 | 0.6602 | No | ||
43 | AIF1 | 1582 23005 | 2306 | 0.056 | 0.6523 | No | ||
44 | NOD2 | 6384 | 2311 | 0.055 | 0.6539 | No | ||
45 | PLA2G7 | 23233 | 2388 | 0.052 | 0.6515 | No | ||
46 | CYSLTR1 | 24082 | 2556 | 0.045 | 0.6440 | No | ||
47 | MLF2 | 17283 | 2698 | 0.040 | 0.6376 | No | ||
48 | AOAH | 11296 | 2993 | 0.032 | 0.6227 | No | ||
49 | AGER | 23276 1576 | 3042 | 0.031 | 0.6211 | No | ||
50 | KNG1 | 9244 22809 | 3078 | 0.030 | 0.6202 | No | ||
51 | CD40 | 10207 2961 2968 5783 | 3285 | 0.026 | 0.6099 | No | ||
52 | MST1R | 19318 3106 | 3320 | 0.025 | 0.6089 | No | ||
53 | ADORA2B | 20850 | 3376 | 0.024 | 0.6067 | No | ||
54 | CXCL9 | 5099 | 3394 | 0.024 | 0.6066 | No | ||
55 | TCIRG1 | 3700 3752 23951 | 3447 | 0.023 | 0.6045 | No | ||
56 | PRF1 | 20011 | 3657 | 0.020 | 0.5938 | No | ||
57 | IRAK2 | 17324 | 3678 | 0.020 | 0.5934 | No | ||
58 | LYST | 9325 5040 | 3721 | 0.019 | 0.5917 | No | ||
59 | PGLYRP2 | 7174 | 3740 | 0.019 | 0.5914 | No | ||
60 | XCR1 | 18953 | 3805 | 0.018 | 0.5885 | No | ||
61 | CCR1 | 18951 | 3816 | 0.018 | 0.5886 | No | ||
62 | C2 | 23013 | 4215 | 0.014 | 0.5674 | No | ||
63 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 4227 | 0.014 | 0.5673 | No | ||
64 | PLA2G2E | 16016 | 4246 | 0.014 | 0.5668 | No | ||
65 | STAB2 | 19656 | 4262 | 0.014 | 0.5664 | No | ||
66 | SFTPD | 21867 | 4364 | 0.013 | 0.5614 | No | ||
67 | AOX1 | 14246 4090 | 4367 | 0.013 | 0.5617 | No | ||
68 | TLR6 | 215 16528 | 4396 | 0.013 | 0.5606 | No | ||
69 | TLR8 | 9308 | 4450 | 0.013 | 0.5582 | No | ||
70 | TNFRSF1A | 1181 10206 | 4458 | 0.013 | 0.5582 | No | ||
71 | CRP | 8793 | 4506 | 0.012 | 0.5561 | No | ||
72 | TLR3 | 18884 | 4608 | 0.012 | 0.5510 | No | ||
73 | CHST2 | 7032 | 4616 | 0.012 | 0.5510 | No | ||
74 | IL18RAP | 14262 | 4629 | 0.012 | 0.5507 | No | ||
75 | GHSR | 1810 15625 | 4728 | 0.011 | 0.5458 | No | ||
76 | NLRP3 | 20862 1262 | 4883 | 0.010 | 0.5377 | No | ||
77 | IFNK | 11837 | 5052 | 0.010 | 0.5289 | No | ||
78 | TIAL1 | 996 5753 | 5079 | 0.009 | 0.5278 | No | ||
79 | CXCL2 | 9790 | 5096 | 0.009 | 0.5273 | No | ||
80 | CD40LG | 24330 | 5259 | 0.009 | 0.5188 | No | ||
81 | NCF1 | 16354 | 5454 | 0.008 | 0.5085 | No | ||
82 | NMI | 14590 | 5456 | 0.008 | 0.5087 | No | ||
83 | CCL24 | 16342 | 5548 | 0.008 | 0.5040 | No | ||
84 | MX1 | 9432 22529 | 5598 | 0.008 | 0.5016 | No | ||
85 | NFATC3 | 5169 | 5702 | 0.007 | 0.4962 | No | ||
86 | EREG | 4679 16797 | 5847 | 0.007 | 0.4886 | No | ||
87 | CCL22 | 18518 | 5954 | 0.006 | 0.4831 | No | ||
88 | CLEC1B | 17270 1080 | 6031 | 0.006 | 0.4792 | No | ||
89 | CD83 | 21653 | 6224 | 0.006 | 0.4689 | No | ||
90 | CD97 | 18822 3874 | 6252 | 0.006 | 0.4676 | No | ||
91 | DEFB103A | 18665 | 6340 | 0.005 | 0.4631 | No | ||
92 | CXCL10 | 16477 | 6392 | 0.005 | 0.4605 | No | ||
93 | COLEC12 | 23624 8946 | 6431 | 0.005 | 0.4586 | No | ||
94 | C5AR1 | 17957 | 6494 | 0.005 | 0.4554 | No | ||
95 | NFATC4 | 22002 | 6522 | 0.005 | 0.4541 | No | ||
96 | IL9 | 21444 | 6632 | 0.004 | 0.4483 | No | ||
97 | PGLYRP3 | 10812 | 6666 | 0.004 | 0.4466 | No | ||
98 | OR2H2 | 17694 | 6753 | 0.004 | 0.4421 | No | ||
99 | APOA4 | 4401 | 6775 | 0.004 | 0.4411 | No | ||
100 | LALBA | 22141 | 6808 | 0.004 | 0.4395 | No | ||
101 | DCDC2 | 9703 | 6841 | 0.004 | 0.4379 | No | ||
102 | CCR3 | 19251 | 6968 | 0.004 | 0.4312 | No | ||
103 | CCL4 | 1362 20730 | 6988 | 0.004 | 0.4303 | No | ||
104 | SELE | 14074 | 7111 | 0.003 | 0.4238 | No | ||
105 | KLRC3 | 16975 | 7261 | 0.003 | 0.4158 | No | ||
106 | APCS | 13748 | 7265 | 0.003 | 0.4157 | No | ||
107 | HDAC9 | 21084 2131 | 7398 | 0.003 | 0.4086 | No | ||
108 | TLR7 | 24004 | 7411 | 0.003 | 0.4081 | No | ||
109 | CCR4 | 18978 | 7475 | 0.003 | 0.4047 | No | ||
110 | PLA2G2D | 16018 | 7494 | 0.003 | 0.4039 | No | ||
111 | ORM2 | 16193 | 7532 | 0.003 | 0.4019 | No | ||
112 | TACR1 | 1082 17403 | 7580 | 0.003 | 0.3995 | No | ||
113 | EDG3 | 21639 | 7700 | 0.002 | 0.3931 | No | ||
114 | DMBT1 | 18050 | 7746 | 0.002 | 0.3907 | No | ||
115 | CXCL1 | 9044 | 7806 | 0.002 | 0.3876 | No | ||
116 | IL20 | 13840 | 7925 | 0.002 | 0.3812 | No | ||
117 | ITK | 4934 | 8044 | 0.002 | 0.3749 | No | ||
118 | C3AR1 | 8668 | 8275 | 0.001 | 0.3624 | No | ||
119 | CD160 | 12023 | 8364 | 0.001 | 0.3577 | No | ||
120 | CCR6 | 1505 23390 | 8425 | 0.001 | 0.3544 | No | ||
121 | LY75 | 9313 5026 | 8950 | 0.000 | 0.3260 | No | ||
122 | ADORA1 | 13831 | 8951 | 0.000 | 0.3260 | No | ||
123 | CCL11 | 20742 | 9193 | -0.000 | 0.3129 | No | ||
124 | CXCL11 | 16478 | 9294 | -0.001 | 0.3075 | No | ||
125 | CHRNA7 | 17808 | 9323 | -0.001 | 0.3060 | No | ||
126 | CCR9 | 8753 | 9452 | -0.001 | 0.2991 | No | ||
127 | IL17C | 18438 | 9521 | -0.001 | 0.2954 | No | ||
128 | IL8RA | 13925 | 9560 | -0.001 | 0.2934 | No | ||
129 | TNFAIP6 | 10203 | 9608 | -0.001 | 0.2908 | No | ||
130 | IL1RL2 | 4212 | 9666 | -0.001 | 0.2878 | No | ||
131 | IL12B | 20918 | 9681 | -0.001 | 0.2871 | No | ||
132 | FOSL1 | 23779 | 9705 | -0.001 | 0.2858 | No | ||
133 | ALOX15 | 20370 | 9745 | -0.001 | 0.2838 | No | ||
134 | WFDC12 | 14356 | 9869 | -0.001 | 0.2771 | No | ||
135 | IFNA2 | 9149 | 10269 | -0.002 | 0.2555 | No | ||
136 | TFF3 | 23038 | 10348 | -0.002 | 0.2514 | No | ||
137 | KLRC2 | 9243 | 10532 | -0.003 | 0.2415 | No | ||
138 | BNIP3 | 17581 | 10612 | -0.003 | 0.2373 | No | ||
139 | PTX3 | 9668 15575 | 10647 | -0.003 | 0.2356 | No | ||
140 | HRH1 | 17321 | 10818 | -0.003 | 0.2264 | No | ||
141 | RIPK2 | 2528 15935 | 10827 | -0.003 | 0.2261 | No | ||
142 | ANKRD1 | 23689 | 11035 | -0.004 | 0.2150 | No | ||
143 | GPR68 | 21004 | 11107 | -0.004 | 0.2112 | No | ||
144 | IL4 | 9174 | 11369 | -0.004 | 0.1972 | No | ||
145 | UMOD | 17660 | 11448 | -0.004 | 0.1931 | No | ||
146 | IL5 | 20884 10220 | 11453 | -0.004 | 0.1930 | No | ||
147 | NCR1 | 18409 | 11573 | -0.005 | 0.1867 | No | ||
148 | PARP4 | 21999 | 11702 | -0.005 | 0.1799 | No | ||
149 | FPRL1 | 8982 | 11984 | -0.006 | 0.1649 | No | ||
150 | ADORA2A | 8557 | 12017 | -0.006 | 0.1633 | No | ||
151 | AOC3 | 8595 | 12247 | -0.006 | 0.1511 | No | ||
152 | IL1A | 4915 | 12286 | -0.006 | 0.1492 | No | ||
153 | ADORA3 | 4352 | 12369 | -0.007 | 0.1450 | No | ||
154 | FOXN1 | 20337 | 12400 | -0.007 | 0.1436 | No | ||
155 | NOX4 | 18196 | 12517 | -0.007 | 0.1375 | No | ||
156 | CRTAM | 19160 | 12718 | -0.008 | 0.1269 | No | ||
157 | GHRL | 1183 17040 | 12733 | -0.008 | 0.1264 | No | ||
158 | DEFB1 | 18663 | 12905 | -0.008 | 0.1174 | No | ||
159 | SCG2 | 5410 14425 | 12945 | -0.008 | 0.1155 | No | ||
160 | IL28RA | 10823 16038 | 12966 | -0.008 | 0.1147 | No | ||
161 | CCR5 | 8754 4534 | 12991 | -0.008 | 0.1137 | No | ||
162 | CADM1 | 7057 | 13194 | -0.009 | 0.1030 | No | ||
163 | SPACA3 | 13680 | 13274 | -0.010 | 0.0991 | No | ||
164 | CX3CL1 | 9791 | 13571 | -0.011 | 0.0834 | No | ||
165 | INHBB | 13858 | 13618 | -0.011 | 0.0812 | No | ||
166 | MBL2 | 23886 | 13768 | -0.012 | 0.0735 | No | ||
167 | CFHR1 | 11926 13815 | 13870 | -0.013 | 0.0685 | No | ||
168 | MX2 | 9433 | 14135 | -0.015 | 0.0546 | No | ||
169 | STAB1 | 21892 | 14231 | -0.015 | 0.0500 | No | ||
170 | MGLL | 17368 1145 | 14312 | -0.016 | 0.0461 | No | ||
171 | F11R | 9199 | 14365 | -0.016 | 0.0439 | No | ||
172 | CYBB | 4579 | 14442 | -0.017 | 0.0403 | No | ||
173 | ELF3 | 8894 13824 | 14464 | -0.017 | 0.0397 | No | ||
174 | CCR2 | 19250 | 14475 | -0.017 | 0.0397 | No | ||
175 | CD5L | 15560 | 14485 | -0.017 | 0.0398 | No | ||
176 | VPS45 | 15242 | 14616 | -0.018 | 0.0334 | No | ||
177 | CDO1 | 8731 | 14683 | -0.019 | 0.0304 | No | ||
178 | CCL3 | 20317 | 14804 | -0.020 | 0.0246 | No | ||
179 | CSF3R | 8804 8803 2326 4565 | 14904 | -0.022 | 0.0199 | No | ||
180 | IL17RB | 21898 | 15007 | -0.023 | 0.0151 | No | ||
181 | RAC1 | 16302 | 15046 | -0.024 | 0.0139 | No | ||
182 | IL1RAP | 1653 1676 4917 1748 1712 9173 | 15067 | -0.024 | 0.0136 | No | ||
183 | KLRG1 | 17014 | 15258 | -0.027 | 0.0041 | No | ||
184 | AHSG | 22812 | 15292 | -0.027 | 0.0033 | No | ||
185 | IL13 | 20461 | 15337 | -0.028 | 0.0018 | No | ||
186 | GATA3 | 9004 | 15410 | -0.030 | -0.0011 | No | ||
187 | PGLYRP4 | 11810 | 15458 | -0.031 | -0.0026 | No | ||
188 | DEFB127 | 622 | 15477 | -0.031 | -0.0026 | No | ||
189 | CAMLG | 21627 | 15554 | -0.033 | -0.0056 | No | ||
190 | PTPRC | 5327 9662 | 15675 | -0.036 | -0.0109 | No | ||
191 | SOCS6 | 12042 7044 | 15727 | -0.038 | -0.0124 | No | ||
192 | SPN | 452 5493 | 15930 | -0.044 | -0.0219 | No | ||
193 | RELA | 23783 | 16089 | -0.050 | -0.0289 | No | ||
194 | TGFB1 | 18332 | 16358 | -0.063 | -0.0413 | No | ||
195 | IL8RB | 8752 4533 | 16550 | -0.072 | -0.0493 | No | ||
196 | LY96 | 14292 | 17046 | -0.108 | -0.0726 | No | ||
197 | ABCF1 | 22996 10329 5897 | 17097 | -0.112 | -0.0716 | No | ||
198 | PTPRCAP | 23767 | 17244 | -0.127 | -0.0753 | No | ||
199 | SCYE1 | 8897 | 17360 | -0.141 | -0.0769 | No | ||
200 | NCF2 | 14098 5151 9446 | 17461 | -0.149 | -0.0774 | No | ||
201 | LGALS3BP | 20129 | 17519 | -0.157 | -0.0753 | No | ||
202 | BNIP3L | 21775 | 17536 | -0.160 | -0.0708 | No | ||
203 | HP | 3805 18750 | 17542 | -0.161 | -0.0658 | No | ||
204 | BLNK | 23681 3691 | 17632 | -0.172 | -0.0649 | No | ||
205 | IL10RB | 9169 | 17744 | -0.186 | -0.0647 | No | ||
206 | RNASE6 | 13439 | 17990 | -0.237 | -0.0702 | No | ||
207 | CCL5 | 20320 | 18259 | -0.362 | -0.0727 | No | ||
208 | MPO | 5116 20710 1324 | 18347 | -0.436 | -0.0629 | No | ||
209 | FOS | 21202 | 18435 | -0.608 | -0.0474 | No | ||
210 | TARBP2 | 10033 10034 5626 | 18480 | -0.807 | -0.0230 | No | ||
211 | HDAC5 | 1480 20205 | 18495 | -0.912 | 0.0066 | No |