Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | V$E2F_Q6_01 |
Enrichment Score (ES) | -0.59160924 |
Normalized Enrichment Score (NES) | -1.3984921 |
Nominal p-value | 0.023605151 |
FDR q-value | 0.7680592 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LIG1 | 18388 1749 1493 | 122 | 1.152 | 0.0496 | No | ||
2 | MCM7 | 9372 3568 | 175 | 0.739 | 0.0828 | No | ||
3 | AXUD1 | 18967 | 194 | 0.664 | 0.1143 | No | ||
4 | MCM4 | 22655 1708 | 403 | 0.367 | 0.1209 | No | ||
5 | KLF5 | 4456 | 502 | 0.312 | 0.1309 | No | ||
6 | TIAM1 | 22547 | 566 | 0.283 | 0.1413 | No | ||
7 | ZCCHC8 | 3570 7696 | 816 | 0.209 | 0.1379 | No | ||
8 | SFRS1 | 8492 | 1253 | 0.139 | 0.1211 | No | ||
9 | CDC25A | 8721 | 1280 | 0.135 | 0.1263 | No | ||
10 | FLI1 | 4729 | 1367 | 0.124 | 0.1277 | No | ||
11 | MXD3 | 21455 | 1559 | 0.105 | 0.1224 | No | ||
12 | HMGN2 | 9095 | 1595 | 0.102 | 0.1255 | No | ||
13 | USP52 | 3397 19841 | 1642 | 0.098 | 0.1278 | No | ||
14 | NHLRC2 | 23828 | 1669 | 0.095 | 0.1310 | No | ||
15 | DMD | 24295 2647 | 1698 | 0.093 | 0.1341 | No | ||
16 | SFRS2 | 9807 20136 | 1747 | 0.089 | 0.1358 | No | ||
17 | DAXX | 23290 | 1752 | 0.089 | 0.1400 | No | ||
18 | PPP1R9B | 20698 | 1877 | 0.081 | 0.1372 | No | ||
19 | DLST | 8131 | 1905 | 0.079 | 0.1396 | No | ||
20 | RBL1 | 14373 | 2098 | 0.065 | 0.1324 | No | ||
21 | MCM3 | 13991 | 2334 | 0.054 | 0.1223 | No | ||
22 | HRBL | 3452 16326 3614 | 2365 | 0.053 | 0.1233 | No | ||
23 | ATE1 | 388 17602 | 2572 | 0.044 | 0.1143 | No | ||
24 | TLE3 | 5767 19416 | 2668 | 0.041 | 0.1111 | No | ||
25 | STMN1 | 9261 | 2749 | 0.038 | 0.1086 | No | ||
26 | UFD1L | 22825 | 2826 | 0.036 | 0.1062 | No | ||
27 | BRMS1L | 21268 | 2943 | 0.033 | 0.1016 | No | ||
28 | RALY | 2718 9690 | 2967 | 0.032 | 0.1019 | No | ||
29 | FANCL | 20938 948 1252 | 3087 | 0.030 | 0.0969 | No | ||
30 | CTCF | 18490 | 3252 | 0.026 | 0.0893 | No | ||
31 | SFMBT1 | 12053 7050 | 3287 | 0.026 | 0.0887 | No | ||
32 | MAZ | 1327 17623 | 3353 | 0.024 | 0.0864 | No | ||
33 | DUSP7 | 10661 | 3370 | 0.024 | 0.0867 | No | ||
34 | DDB2 | 2721 2878 14525 2661 | 3464 | 0.023 | 0.0828 | No | ||
35 | FANCG | 15904 | 3467 | 0.023 | 0.0838 | No | ||
36 | ADAMTS2 | 5706 20899 1356 | 3477 | 0.023 | 0.0844 | No | ||
37 | STAG2 | 5521 | 3577 | 0.021 | 0.0801 | No | ||
38 | SLC6A4 | 20770 | 3668 | 0.020 | 0.0762 | No | ||
39 | BCOR | 12934 2561 | 3862 | 0.018 | 0.0666 | No | ||
40 | CDC45L | 22642 1752 | 4061 | 0.016 | 0.0566 | No | ||
41 | RAD51 | 2897 14903 | 4130 | 0.015 | 0.0537 | No | ||
42 | STAG1 | 5520 9905 2987 | 4134 | 0.015 | 0.0542 | No | ||
43 | DNMT1 | 19217 | 4210 | 0.014 | 0.0509 | No | ||
44 | PTMA | 9657 | 4223 | 0.014 | 0.0509 | No | ||
45 | ETV4 | 20212 | 4309 | 0.014 | 0.0470 | No | ||
46 | CITED2 | 5118 14477 | 4423 | 0.013 | 0.0415 | No | ||
47 | DCLRE1A | 23641 | 4553 | 0.012 | 0.0351 | No | ||
48 | FBXO5 | 19830 | 5098 | 0.009 | 0.0061 | No | ||
49 | IPO7 | 6130 | 5103 | 0.009 | 0.0063 | No | ||
50 | SLITRK3 | 11816 | 5144 | 0.009 | 0.0046 | No | ||
51 | PCSK4 | 19696 3296 3394 18705 | 5319 | 0.008 | -0.0044 | No | ||
52 | SNCB | 21456 | 5426 | 0.008 | -0.0098 | No | ||
53 | CACNA1G | 1237 940 20292 | 5717 | 0.007 | -0.0251 | No | ||
54 | SLITRK4 | 24144 | 5870 | 0.007 | -0.0330 | No | ||
55 | MAP3K13 | 22814 | 5992 | 0.006 | -0.0393 | No | ||
56 | SALL1 | 18796 12207 | 6096 | 0.006 | -0.0446 | No | ||
57 | PODN | 15811 | 6445 | 0.005 | -0.0632 | No | ||
58 | GRIA4 | 19249 | 6639 | 0.004 | -0.0734 | No | ||
59 | NRP2 | 5194 9486 5195 | 6758 | 0.004 | -0.0796 | No | ||
60 | HTR2C | 24230 | 6777 | 0.004 | -0.0804 | No | ||
61 | ERBB2IP | 3232 12234 | 6809 | 0.004 | -0.0819 | No | ||
62 | HNRPD | 8645 | 7163 | 0.003 | -0.1008 | No | ||
63 | PCDH7 | 7029 3460 | 7582 | 0.003 | -0.1233 | No | ||
64 | GLRA3 | 18617 | 7695 | 0.002 | -0.1293 | No | ||
65 | NKX2-2 | 5176 | 7971 | 0.002 | -0.1441 | No | ||
66 | LUC7L2 | 5313 5312 | 8039 | 0.002 | -0.1476 | No | ||
67 | ARID4A | 2080 6215 | 8168 | 0.001 | -0.1545 | No | ||
68 | KCND2 | 4941 17515 | 8518 | 0.001 | -0.1734 | No | ||
69 | PEG3 | 5240 | 8536 | 0.001 | -0.1742 | No | ||
70 | RPS6KA5 | 2076 21005 | 8609 | 0.001 | -0.1781 | No | ||
71 | EZH2 | 1092 17163 | 8828 | 0.000 | -0.1899 | No | ||
72 | ATAD2 | 2268 2256 | 8840 | 0.000 | -0.1905 | No | ||
73 | PAQR4 | 23105 | 9093 | -0.000 | -0.2041 | No | ||
74 | REPS2 | 24018 | 9121 | -0.000 | -0.2056 | No | ||
75 | ORC1L | 327 16144 | 9197 | -0.000 | -0.2096 | No | ||
76 | FMO4 | 13786 | 9259 | -0.001 | -0.2129 | No | ||
77 | ACIN1 | 3319 2807 21832 | 9637 | -0.001 | -0.2333 | No | ||
78 | DMRT1 | 23899 | 9675 | -0.001 | -0.2352 | No | ||
79 | ADAMTS9 | 17063 | 9697 | -0.001 | -0.2363 | No | ||
80 | POLE2 | 21053 | 9793 | -0.001 | -0.2414 | No | ||
81 | CASP8AP2 | 16253 | 9852 | -0.001 | -0.2445 | No | ||
82 | MYC | 22465 9435 | 10267 | -0.002 | -0.2668 | No | ||
83 | CBX5 | 22108 4485 | 10524 | -0.003 | -0.2805 | No | ||
84 | PRKDC | 9617 22847 | 10531 | -0.003 | -0.2807 | No | ||
85 | RANBP1 | 9692 5357 | 10694 | -0.003 | -0.2893 | No | ||
86 | BMP7 | 14324 | 11007 | -0.004 | -0.3061 | No | ||
87 | E2F7 | 19884 | 11342 | -0.004 | -0.3240 | No | ||
88 | PLK4 | 1870 1874 | 11619 | -0.005 | -0.3387 | No | ||
89 | HIST1H1D | 4821 | 11883 | -0.005 | -0.3526 | No | ||
90 | HNRPA1 | 9103 4860 | 11949 | -0.006 | -0.3559 | No | ||
91 | BAI1 | 22459 | 12324 | -0.007 | -0.3758 | No | ||
92 | BARHL1 | 14634 | 12441 | -0.007 | -0.3818 | No | ||
93 | E2F3 | 21500 8874 | 12497 | -0.007 | -0.3844 | No | ||
94 | CDC6 | 6221 6220 | 12711 | -0.008 | -0.3956 | No | ||
95 | KLHDC3 | 22956 | 12880 | -0.008 | -0.4043 | No | ||
96 | KCNA6 | 664 16990 665 4938 | 13072 | -0.009 | -0.4142 | No | ||
97 | H2AFZ | 6957 | 13127 | -0.009 | -0.4167 | No | ||
98 | WEE1 | 18127 | 13180 | -0.009 | -0.4191 | No | ||
99 | EPHB1 | 19024 | 13238 | -0.009 | -0.4217 | No | ||
100 | ERG | 1686 8915 | 13370 | -0.010 | -0.4283 | No | ||
101 | DLL4 | 7040 | 13405 | -0.010 | -0.4296 | No | ||
102 | RRM2 | 5401 5400 | 13596 | -0.011 | -0.4394 | No | ||
103 | PVRL1 | 3006 19482 12211 7192 | 13902 | -0.013 | -0.4553 | No | ||
104 | DNAJC11 | 2486 6068 | 13975 | -0.014 | -0.4585 | No | ||
105 | MCM6 | 4000 13845 4119 | 14357 | -0.016 | -0.4784 | No | ||
106 | TBX3 | 16723 | 14556 | -0.018 | -0.4882 | No | ||
107 | HOXA9 | 17147 9109 1024 | 14728 | -0.019 | -0.4965 | No | ||
108 | SLC16A2 | 24086 | 14758 | -0.020 | -0.4971 | No | ||
109 | TOPBP1 | 10659 | 14908 | -0.022 | -0.5041 | No | ||
110 | XPO5 | 7802 | 14958 | -0.022 | -0.5057 | No | ||
111 | SEMA5A | 22496 5423 | 15076 | -0.024 | -0.5109 | No | ||
112 | NDUFA11 | 12832 | 15088 | -0.024 | -0.5103 | No | ||
113 | E2F1 | 14384 | 15124 | -0.025 | -0.5110 | No | ||
114 | MELK | 2453 16227 | 15126 | -0.025 | -0.5098 | No | ||
115 | RAB11B | 9676 | 15178 | -0.026 | -0.5114 | No | ||
116 | CASP2 | 8692 | 15213 | -0.026 | -0.5119 | No | ||
117 | CLPTM1 | 17940 | 15465 | -0.031 | -0.5240 | No | ||
118 | PHF15 | 20467 8050 | 15517 | -0.032 | -0.5252 | No | ||
119 | AP4M1 | 3499 16656 | 15556 | -0.033 | -0.5256 | No | ||
120 | CYR61 | 9159 15145 9311 5024 | 15858 | -0.042 | -0.5399 | No | ||
121 | ANP32E | 15500 | 15859 | -0.042 | -0.5379 | No | ||
122 | APRIN | 4145 | 16088 | -0.050 | -0.5478 | No | ||
123 | MAT2A | 10553 10554 6099 | 16236 | -0.057 | -0.5529 | No | ||
124 | GMNN | 21513 | 16269 | -0.058 | -0.5518 | No | ||
125 | TNPO2 | 5608 | 16316 | -0.061 | -0.5514 | No | ||
126 | MCM2 | 17074 | 16530 | -0.071 | -0.5595 | No | ||
127 | ACBD6 | 14089 | 16571 | -0.073 | -0.5580 | No | ||
128 | SUV39H1 | 24194 | 16616 | -0.076 | -0.5567 | No | ||
129 | GPRC5B | 17662 | 16709 | -0.083 | -0.5577 | No | ||
130 | PPM1D | 20721 | 16933 | -0.098 | -0.5650 | No | ||
131 | RFC1 | 16527 | 17209 | -0.123 | -0.5738 | No | ||
132 | CDCA7 | 12437 | 17538 | -0.160 | -0.5838 | Yes | ||
133 | PRKCSH | 19535 | 17597 | -0.167 | -0.5788 | Yes | ||
134 | KPNB1 | 20274 | 17697 | -0.180 | -0.5754 | Yes | ||
135 | NCL | 5153 13899 | 17718 | -0.182 | -0.5676 | Yes | ||
136 | POLD1 | 17847 | 17746 | -0.187 | -0.5599 | Yes | ||
137 | PRIM1 | 19847 | 17773 | -0.191 | -0.5520 | Yes | ||
138 | DCK | 16808 | 17832 | -0.199 | -0.5454 | Yes | ||
139 | POLH | 22966 | 17846 | -0.201 | -0.5363 | Yes | ||
140 | FBXL20 | 13010 | 17887 | -0.212 | -0.5281 | Yes | ||
141 | RPS19 | 5398 | 17922 | -0.220 | -0.5193 | Yes | ||
142 | TMEM4 | 19842 | 18092 | -0.270 | -0.5152 | Yes | ||
143 | NUTF2 | 12632 7529 | 18118 | -0.279 | -0.5030 | Yes | ||
144 | RBBP4 | 5364 | 18181 | -0.305 | -0.4914 | Yes | ||
145 | YWHAQ | 10369 | 18214 | -0.327 | -0.4772 | Yes | ||
146 | UNG | 10257 16744 | 18215 | -0.327 | -0.4613 | Yes | ||
147 | UCHL1 | 16834 | 18321 | -0.409 | -0.4470 | Yes | ||
148 | CDKN1A | 4511 8729 | 18339 | -0.430 | -0.4269 | Yes | ||
149 | PCNA | 9535 | 18352 | -0.446 | -0.4058 | Yes | ||
150 | HTF9C | 4886 1678 | 18378 | -0.484 | -0.3836 | Yes | ||
151 | EIF5A | 11345 20379 6590 | 18409 | -0.534 | -0.3591 | Yes | ||
152 | DUSP6 | 19891 3399 | 18525 | -1.221 | -0.3058 | Yes | ||
153 | NASP | 2383 2387 6955 | 18528 | -1.233 | -0.2457 | Yes | ||
154 | DPYSL2 | 3122 4561 8787 | 18616 | -5.131 | -0.0000 | Yes |