Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | V$DR1_Q3 |
Enrichment Score (ES) | -0.6097337 |
Normalized Enrichment Score (NES) | -1.4651071 |
Nominal p-value | 0.013422819 |
FDR q-value | 1.0 |
FWER p-Value | 0.998 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NEDD9 | 3206 21483 | 320 | 0.441 | 0.0064 | No | ||
2 | ESRRA | 23802 | 527 | 0.299 | 0.0114 | No | ||
3 | SEPX1 | 1600 23353 | 570 | 0.281 | 0.0243 | No | ||
4 | GTF3C2 | 7749 | 585 | 0.276 | 0.0384 | No | ||
5 | LAMP2 | 9267 2653 | 590 | 0.274 | 0.0530 | No | ||
6 | TMEM24 | 19150 | 591 | 0.274 | 0.0678 | No | ||
7 | VCL | 22083 | 701 | 0.238 | 0.0748 | No | ||
8 | MARK2 | 8899 | 741 | 0.226 | 0.0849 | No | ||
9 | SATB1 | 5408 | 886 | 0.195 | 0.0876 | No | ||
10 | PGF | 21020 | 1215 | 0.143 | 0.0775 | No | ||
11 | AGPS | 14979 | 1272 | 0.136 | 0.0818 | No | ||
12 | EIF4G1 | 22818 | 1424 | 0.118 | 0.0800 | No | ||
13 | NPHP4 | 15978 | 1563 | 0.104 | 0.0782 | No | ||
14 | USP52 | 3397 19841 | 1642 | 0.098 | 0.0792 | No | ||
15 | DMD | 24295 2647 | 1698 | 0.093 | 0.0813 | No | ||
16 | RBBP6 | 5365 | 1823 | 0.084 | 0.0791 | No | ||
17 | PCTK1 | 24369 | 1891 | 0.080 | 0.0798 | No | ||
18 | TLK2 | 20628 | 1926 | 0.078 | 0.0821 | No | ||
19 | BIN3 | 21969 | 1951 | 0.076 | 0.0849 | No | ||
20 | ZSWIM3 | 14733 | 2024 | 0.071 | 0.0848 | No | ||
21 | MAP3K11 | 11163 | 2083 | 0.067 | 0.0853 | No | ||
22 | RBMS1 | 14580 | 2099 | 0.065 | 0.0880 | No | ||
23 | NR2F1 | 7015 21401 | 2269 | 0.057 | 0.0819 | No | ||
24 | RBKS | 16568 | 2284 | 0.057 | 0.0843 | No | ||
25 | LRP1 | 9284 | 2391 | 0.052 | 0.0813 | No | ||
26 | CLDN15 | 16667 3572 | 2403 | 0.051 | 0.0835 | No | ||
27 | SOX5 | 9850 1044 5480 16937 | 2527 | 0.046 | 0.0793 | No | ||
28 | RASAL1 | 16719 | 2712 | 0.039 | 0.0714 | No | ||
29 | HSD17B8 | 9061 | 2760 | 0.038 | 0.0709 | No | ||
30 | SMTN | 20551 1446 | 2840 | 0.035 | 0.0685 | No | ||
31 | RQCD1 | 12205 | 2973 | 0.032 | 0.0631 | No | ||
32 | SFRS6 | 14751 | 3050 | 0.031 | 0.0606 | No | ||
33 | SYT4 | 5566 | 3186 | 0.028 | 0.0548 | No | ||
34 | HIP2 | 3626 3485 16838 | 3260 | 0.026 | 0.0523 | No | ||
35 | BAALC | 4407 2201 | 3347 | 0.025 | 0.0489 | No | ||
36 | SS18 | 6506 6505 2030 | 3378 | 0.024 | 0.0486 | No | ||
37 | NCDN | 15756 2487 6471 | 3455 | 0.023 | 0.0457 | No | ||
38 | SELM | 20967 | 3558 | 0.021 | 0.0414 | No | ||
39 | PRRX2 | 15047 | 3588 | 0.021 | 0.0409 | No | ||
40 | SNAP25 | 5466 | 3833 | 0.018 | 0.0287 | No | ||
41 | CLDN10 | 21935 2785 2601 2720 7188 | 3853 | 0.018 | 0.0286 | No | ||
42 | TIMELESS | 10177 | 3901 | 0.017 | 0.0270 | No | ||
43 | DNMT3A | 2167 21330 | 4045 | 0.016 | 0.0201 | No | ||
44 | PRODH2 | 1854 18300 | 4207 | 0.014 | 0.0121 | No | ||
45 | PDZK1 | 15490 | 4536 | 0.012 | -0.0050 | No | ||
46 | HOXB3 | 20685 | 4603 | 0.012 | -0.0080 | No | ||
47 | HSPE1 | 9133 | 4607 | 0.012 | -0.0075 | No | ||
48 | LMX1B | 14616 | 4634 | 0.012 | -0.0083 | No | ||
49 | UBE2R2 | 16240 | 4685 | 0.011 | -0.0104 | No | ||
50 | ZIC4 | 5992 | 4761 | 0.011 | -0.0138 | No | ||
51 | OVOL1 | 23983 | 4802 | 0.011 | -0.0154 | No | ||
52 | YBX2 | 20818 | 4848 | 0.010 | -0.0173 | No | ||
53 | GDPD2 | 24280 | 4893 | 0.010 | -0.0191 | No | ||
54 | PLEC1 | 2273 2198 2205 2178 2230 22247 2213 2231 2295 2172 5263 2266 | 5498 | 0.008 | -0.0515 | No | ||
55 | FGFR3 | 8969 3566 | 5865 | 0.007 | -0.0709 | No | ||
56 | PLA2G2F | 15700 | 6062 | 0.006 | -0.0812 | No | ||
57 | ADAMTS19 | 23544 | 6366 | 0.005 | -0.0974 | No | ||
58 | NR2F2 | 8619 409 | 6497 | 0.005 | -0.1042 | No | ||
59 | FBLN1 | 4716 2208 | 6671 | 0.004 | -0.1133 | No | ||
60 | REST | 16818 | 6743 | 0.004 | -0.1169 | No | ||
61 | TOMM70A | 6608 | 6756 | 0.004 | -0.1174 | No | ||
62 | PPP1R14D | 14471 | 6770 | 0.004 | -0.1178 | No | ||
63 | CKAP4 | 19663 | 6856 | 0.004 | -0.1222 | No | ||
64 | STMN2 | 15638 | 6864 | 0.004 | -0.1224 | No | ||
65 | PRDM16 | 12893 | 6904 | 0.004 | -0.1243 | No | ||
66 | GOLGA4 | 12022 | 7030 | 0.004 | -0.1309 | No | ||
67 | CNTFR | 2515 15906 | 7282 | 0.003 | -0.1443 | No | ||
68 | INHBC | 19603 | 7430 | 0.003 | -0.1521 | No | ||
69 | PIPOX | 20340 | 7535 | 0.003 | -0.1576 | No | ||
70 | PCDH7 | 7029 3460 | 7582 | 0.003 | -0.1600 | No | ||
71 | SLC7A9 | 18291 1766 | 7607 | 0.003 | -0.1611 | No | ||
72 | GDNF | 22514 2275 | 7937 | 0.002 | -0.1789 | No | ||
73 | NRAP | 23642 | 8325 | 0.001 | -0.1998 | No | ||
74 | HS6ST2 | 6939 2646 | 8333 | 0.001 | -0.2001 | No | ||
75 | TOM1L2 | 10115 | 8337 | 0.001 | -0.2002 | No | ||
76 | NR4A3 | 9473 16212 5183 | 8351 | 0.001 | -0.2009 | No | ||
77 | MAP2K3 | 20856 | 8519 | 0.001 | -0.2099 | No | ||
78 | NEUROG2 | 15426 | 8524 | 0.001 | -0.2100 | No | ||
79 | PRDM1 | 19775 3337 | 8528 | 0.001 | -0.2102 | No | ||
80 | PTPRG | 22097 3151 | 8637 | 0.001 | -0.2160 | No | ||
81 | TCF1 | 16416 | 8741 | 0.000 | -0.2215 | No | ||
82 | LMOD3 | 17059 | 8871 | 0.000 | -0.2285 | No | ||
83 | CRABP2 | 15554 | 8886 | 0.000 | -0.2293 | No | ||
84 | HMGCS2 | 15483 | 9161 | -0.000 | -0.2441 | No | ||
85 | CLCNKA | 15690 | 9164 | -0.000 | -0.2442 | No | ||
86 | NFE2L2 | 2898 14557 | 9171 | -0.000 | -0.2445 | No | ||
87 | HOXD3 | 9115 | 9206 | -0.000 | -0.2463 | No | ||
88 | PAPLN | 9301 | 9416 | -0.001 | -0.2576 | No | ||
89 | KCNE1L | 24044 | 9501 | -0.001 | -0.2621 | No | ||
90 | TNNI1 | 14116 | 9558 | -0.001 | -0.2651 | No | ||
91 | DUSP3 | 1358 13022 | 9566 | -0.001 | -0.2654 | No | ||
92 | ARHGEF7 | 3823 | 9605 | -0.001 | -0.2674 | No | ||
93 | EFNB3 | 20391 | 9703 | -0.001 | -0.2726 | No | ||
94 | CDX1 | 23429 | 9719 | -0.001 | -0.2734 | No | ||
95 | NR2C1 | 10215 | 9908 | -0.001 | -0.2835 | No | ||
96 | POU5F1 | 1547 23255 | 10092 | -0.002 | -0.2933 | No | ||
97 | DNAJA2 | 12133 18806 | 10432 | -0.002 | -0.3116 | No | ||
98 | NR4A1 | 9099 | 10437 | -0.002 | -0.3116 | No | ||
99 | TNRC4 | 15514 | 10496 | -0.003 | -0.3146 | No | ||
100 | F12 | 3260 21453 | 10610 | -0.003 | -0.3206 | No | ||
101 | BNIP3 | 17581 | 10612 | -0.003 | -0.3205 | No | ||
102 | CSF2 | 20454 | 10990 | -0.003 | -0.3408 | No | ||
103 | TREX1 | 10219 3111 | 11032 | -0.004 | -0.3428 | No | ||
104 | MOSPD2 | 24009 | 11083 | -0.004 | -0.3453 | No | ||
105 | PDLIM7 | 7434 | 11156 | -0.004 | -0.3490 | No | ||
106 | HOXA3 | 9108 1075 | 11197 | -0.004 | -0.3510 | No | ||
107 | CLCN2 | 22637 | 11483 | -0.004 | -0.3662 | No | ||
108 | USP12 | 5825 5824 | 11532 | -0.005 | -0.3685 | No | ||
109 | NFE2L3 | 17446 | 11581 | -0.005 | -0.3709 | No | ||
110 | GPR124 | 18643 918 | 11601 | -0.005 | -0.3717 | No | ||
111 | TTYH2 | 8585 4382 20605 | 11724 | -0.005 | -0.3780 | No | ||
112 | HOXB6 | 20688 | 11908 | -0.005 | -0.3876 | No | ||
113 | NDUFS1 | 13940 | 12045 | -0.006 | -0.3947 | No | ||
114 | PAK1IP1 | 21660 | 12066 | -0.006 | -0.3954 | No | ||
115 | INSR | 18950 | 12083 | -0.006 | -0.3960 | No | ||
116 | PAX7 | 15697 | 12415 | -0.007 | -0.4136 | No | ||
117 | SLC7A7 | 21837 2911 | 12523 | -0.007 | -0.4190 | No | ||
118 | LRRN1 | 17343 | 12551 | -0.007 | -0.4201 | No | ||
119 | SLC39A5 | 3364 19596 | 12606 | -0.007 | -0.4226 | No | ||
120 | EFEMP1 | 20937 | 12642 | -0.007 | -0.4241 | No | ||
121 | SOD1 | 9846 | 12914 | -0.008 | -0.4383 | No | ||
122 | CALM1 | 21184 | 12968 | -0.008 | -0.4408 | No | ||
123 | FGF9 | 8966 | 13102 | -0.009 | -0.4475 | No | ||
124 | HOXC13 | 22344 | 13107 | -0.009 | -0.4472 | No | ||
125 | PLCD4 | 9587 | 13282 | -0.010 | -0.4561 | No | ||
126 | RTN4 | 7569 1328 1343 1442 | 13433 | -0.010 | -0.4637 | No | ||
127 | ERBB2 | 8913 | 13586 | -0.011 | -0.4714 | No | ||
128 | TTYH1 | 2496 7176 | 13685 | -0.012 | -0.4760 | No | ||
129 | GRPEL1 | 16863 | 13752 | -0.012 | -0.4790 | No | ||
130 | MASP2 | 2547 | 14009 | -0.014 | -0.4921 | No | ||
131 | SLC23A3 | 10367 | 14760 | -0.020 | -0.5317 | No | ||
132 | TCN2 | 20550 | 15022 | -0.023 | -0.5446 | No | ||
133 | PTHR1 | 5318 18985 | 15137 | -0.025 | -0.5494 | No | ||
134 | DPF3 | 7659 12853 | 15325 | -0.028 | -0.5580 | No | ||
135 | MOSPD1 | 12868 12869 7672 | 15826 | -0.041 | -0.5829 | No | ||
136 | LGI4 | 18296 | 15841 | -0.041 | -0.5815 | No | ||
137 | ARFGEF2 | 14728 | 15861 | -0.042 | -0.5803 | No | ||
138 | ATP5O | 22539 | 16134 | -0.052 | -0.5922 | No | ||
139 | MCART1 | 10492 | 16237 | -0.057 | -0.5946 | No | ||
140 | NR2F6 | 4651 8876 18848 8912 | 16411 | -0.065 | -0.6005 | Yes | ||
141 | SSH2 | 6202 | 16461 | -0.067 | -0.5996 | Yes | ||
142 | PPARGC1A | 16533 | 16471 | -0.068 | -0.5964 | Yes | ||
143 | AOC2 | 20658 1256 | 16513 | -0.070 | -0.5949 | Yes | ||
144 | NET1 | 7100 | 16555 | -0.072 | -0.5932 | Yes | ||
145 | MYH10 | 8077 | 16669 | -0.079 | -0.5951 | Yes | ||
146 | SMYD5 | 17386 | 16682 | -0.081 | -0.5914 | Yes | ||
147 | GBL | 23091 1612 | 16757 | -0.086 | -0.5907 | Yes | ||
148 | STOML2 | 15902 | 16775 | -0.088 | -0.5869 | Yes | ||
149 | PAK4 | 17909 | 16798 | -0.090 | -0.5832 | Yes | ||
150 | MAGMAS | 1677 22678 | 16871 | -0.094 | -0.5820 | Yes | ||
151 | USP37 | 13923 | 16997 | -0.104 | -0.5832 | Yes | ||
152 | DCTN1 | 1100 17392 | 17316 | -0.135 | -0.5931 | Yes | ||
153 | POLR2H | 10888 | 17623 | -0.171 | -0.6005 | Yes | ||
154 | PSMF1 | 6009 | 17687 | -0.178 | -0.5943 | Yes | ||
155 | PFN1 | 9555 | 17745 | -0.186 | -0.5873 | Yes | ||
156 | HSPD1 | 4078 9129 | 17794 | -0.194 | -0.5794 | Yes | ||
157 | AP1B1 | 8599 | 17866 | -0.206 | -0.5722 | Yes | ||
158 | MRPL11 | 23774 | 17898 | -0.214 | -0.5623 | Yes | ||
159 | FKBP5 | 23051 | 17911 | -0.216 | -0.5513 | Yes | ||
160 | EEF1B2 | 4131 12063 | 17949 | -0.226 | -0.5411 | Yes | ||
161 | BRE | 3640 4226 16879 | 17959 | -0.228 | -0.5293 | Yes | ||
162 | ZBTB12 | 23268 | 18198 | -0.321 | -0.5249 | Yes | ||
163 | PCBP4 | 12235 | 18219 | -0.328 | -0.5083 | Yes | ||
164 | SLC25A1 | 22645 | 18264 | -0.364 | -0.4910 | Yes | ||
165 | HIBADH | 17144 | 18270 | -0.367 | -0.4715 | Yes | ||
166 | TP53 | 20822 | 18592 | -2.086 | -0.3763 | Yes | ||
167 | BOK | 11953 14174 | 18608 | -3.285 | -0.1998 | Yes | ||
168 | DCTN2 | 7635 12812 | 18611 | -3.709 | 0.0003 | Yes |