Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB
Phenotype	phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	-0.6333713
Normalized Enrichment Score (NES)	-1.4508531
Nominal p-value	0.03253796
FDR q-value	0.8595763
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR2E	3325 19699	107	1.249	0.0531	No
2	PDE6D	13897 3945	115	1.172	0.1080	No
3	XDH	22897	342	0.417	0.1154	No
4	RRM1	18163	507	0.311	0.1212	No
5	PDE4B	9543	1057	0.166	0.0993	No
6	POLE	16755	1329	0.129	0.0907	No
7	NT5C2	3768 8052	1363	0.125	0.0948	No
8	ADCY9	22680	1425	0.118	0.0971	No
9	POLR2J	16672	1444	0.116	0.1016	No
10	FHIT	21920	1481	0.112	0.1049	No
11	HPRT1	2655 24339 408	1551	0.106	0.1062	No
12	POLR3A	21900	1596	0.102	0.1086	No
13	ENPP1	19804	1854	0.082	0.0986	No
14	POLR2I	12839	2115	0.064	0.0876	No
15	POLD4	12822	2142	0.063	0.0892	No
16	PDE4C	8481	2729	0.039	0.0593	No
17	ADCY6	22139 2283 8551	2830	0.035	0.0556	No
18	NME6	3139 19297	2959	0.032	0.0502	No
19	POLR2G	23753	3189	0.028	0.0391	No
20	AMPD1	5051	3246	0.027	0.0373	No
21	ECGF1	22160	3486	0.023	0.0254	No
22	NT5E	19360 18702	3579	0.021	0.0215	No
23	GDA	4764	3675	0.020	0.0172	No
24	GUCY1B3	15311	3679	0.020	0.0180	No
25	PDE4A	3037 19542 3083 3023	3810	0.018	0.0118	No
26	PKLR	1850 15545	3844	0.018	0.0109	No
27	GUCY1A3	7216 12245 15310	3897	0.017	0.0089	No
28	PDE7B	19807	3963	0.017	0.0062	No
29	ENTPD6	4496 2678	4307	0.014	-0.0118	No
30	AK1	4363	4469	0.013	-0.0199	No
31	PNPT1	20936	4828	0.011	-0.0387	No
32	NT5M	8345 4175	4884	0.010	-0.0412	No
33	NME7	926 4101 14070 3986 3946 931	5152	0.009	-0.0552	No
34	ENTPD8	12996	5336	0.008	-0.0647	No
35	AMPD3	4383 2110	5370	0.008	-0.0661	No
36	GMPR2	2711	5464	0.008	-0.0708	No
37	PDE8B	5756	5927	0.006	-0.0955	No
38	POLR2C	9750	6278	0.005	-0.1142	No
39	PDE9A	23301	6701	0.004	-0.1368	No
40	PDE1C	5235	6716	0.004	-0.1373	No
41	ADCY5	10312	6880	0.004	-0.1460	No
42	AK5	6042	6946	0.004	-0.1493	No
43	PDE10A	23387	6970	0.004	-0.1504	No
44	ALLC	21093 2130	7081	0.004	-0.1561	No
45	ADCY2	21412	7149	0.003	-0.1596	No
46	GUCY2C	1140 16954	7169	0.003	-0.1605	No
47	POLA1	24112	7190	0.003	-0.1614	No
48	PDE6G	20119	7510	0.003	-0.1785	No
49	ENTPD1	4495	7588	0.003	-0.1826	No
50	GUCY2F	24045	7883	0.002	-0.1984	No
51	POLR2B	16817	7996	0.002	-0.2044	No
52	ITPA	9193	8228	0.001	-0.2168	No
53	PDE11A	10805	8387	0.001	-0.2253	No
54	ADCY3	21329 894	9063	-0.000	-0.2618	No
55	ADCY8	22281	9222	-0.000	-0.2703	No
56	ADK	3302 3454 8555	9381	-0.001	-0.2788	No
57	POLE2	21053	9793	-0.001	-0.3010	No
58	ADCY4	2980 21818	10062	-0.002	-0.3154	No
59	PAPSS2	6258	10962	-0.003	-0.3639	No
60	RRM2B	6902 6903 11801	11023	-0.004	-0.3670	No
61	ENTPD3	19266	11757	-0.005	-0.4064	No
62	ENTPD2	8713	11784	-0.005	-0.4075	No
63	NPR2	16230	11788	-0.005	-0.4074	No
64	PDE6H	17257	12048	-0.006	-0.4212	No
65	AMPD2	1931 15197	12251	-0.006	-0.4318	No
66	POLR3K	12447 7372	12445	-0.007	-0.4419	No
67	ENTPD4	7449	12938	-0.008	-0.4681	No
68	AK3L1	8564	13124	-0.009	-0.4777	No
69	GUCY1A2	19580	13211	-0.009	-0.4819	No
70	ENPP3	19803	13516	-0.011	-0.4979	No
71	RRM2	5401 5400	13596	-0.011	-0.5016	No
72	POLR1D	3593 3658 16623	13609	-0.011	-0.5017	No
73	PDE1A	9541 5234	13627	-0.011	-0.5021	No
74	POLR1B	14857	13865	-0.013	-0.5143	No
75	CANT1	13304	13900	-0.013	-0.5156	No
76	GART	22543 1754	14162	-0.015	-0.5290	No
77	NT5C1B	21315	14385	-0.016	-0.5402	No
78	PDE4D	10722 6235	14994	-0.023	-0.5720	No
79	PRPS2	24003	15111	-0.025	-0.5772	No
80	NPR1	9480	15690	-0.037	-0.6067	No
81	POLR2A	5394	15711	-0.037	-0.6060	No
82	APRT	8620	15911	-0.043	-0.6147	No
83	NT5C	20151	16035	-0.048	-0.6191	No
84	IMPDH2	10730	16040	-0.048	-0.6170	No
85	DGUOK	17099 1041	16062	-0.049	-0.6159	No
86	NUDT2	16239	16097	-0.050	-0.6153	No
87	PKM2	3642 9573	16205	-0.056	-0.6185	No
88	POLD3	17742	16230	-0.057	-0.6171	No
89	IMPDH1	17197 1131	16527	-0.070	-0.6298	No
90	POLE4	12441	16594	-0.075	-0.6299	Yes
91	POLR1A	9749 5393	16609	-0.076	-0.6271	Yes
92	PDE7A	9544 1788	16615	-0.076	-0.6237	Yes
93	PDE5A	15431	16624	-0.077	-0.6205	Yes
94	PAPSS1	15419	16703	-0.082	-0.6209	Yes
95	POLE3	7200	16748	-0.086	-0.6192	Yes
96	AK2	8563 2479 16073	16788	-0.089	-0.6171	Yes
97	ADA	2703 14361	16857	-0.093	-0.6164	Yes
98	NT5C3	17136	16899	-0.096	-0.6141	Yes
99	PDE2A	18170	16916	-0.097	-0.6104	Yes
100	GMPR	21651	16974	-0.102	-0.6087	Yes
101	PAICS	16820	16994	-0.104	-0.6048	Yes
102	NUDT9	7897	17008	-0.105	-0.6006	Yes
103	GUK1	20432	17082	-0.110	-0.5993	Yes
104	POLR2K	9413	17152	-0.117	-0.5975	Yes
105	POLD2	20537	17227	-0.125	-0.5956	Yes
106	PDE3B	5236	17283	-0.132	-0.5924	Yes
107	GMPS	15578	17344	-0.139	-0.5891	Yes
108	POLA2	23988	17357	-0.140	-0.5831	Yes
109	ZNRD1	1491 22987	17365	-0.141	-0.5769	Yes
110	ADSL	4358	17460	-0.149	-0.5749	Yes
111	PDE8A	18202	17467	-0.149	-0.5682	Yes
112	POLR3B	12875	17526	-0.158	-0.5639	Yes
113	ADCY7	8552 448	17585	-0.166	-0.5592	Yes
114	POLR3H	13460 8135	17586	-0.166	-0.5514	Yes
115	POLR2H	10888	17623	-0.171	-0.5453	Yes
116	POLD1	17847	17746	-0.187	-0.5431	Yes
117	PRIM1	19847	17773	-0.191	-0.5355	Yes
118	DCK	16808	17832	-0.199	-0.5292	Yes
119	NME4	23065 1577	17834	-0.200	-0.5199	Yes
120	ENTPD5	4497	17842	-0.201	-0.5108	Yes
121	PPAT	6081	18001	-0.240	-0.5080	Yes
122	ATIC	14231 3968	18078	-0.266	-0.4996	Yes
123	NME2	9468	18085	-0.268	-0.4873	Yes
124	NME1	9467	18100	-0.274	-0.4751	Yes
125	NUDT5	15121	18195	-0.316	-0.4653	Yes
126	PRPS1	24233	18248	-0.353	-0.4515	Yes
127	ADSSL1	21136 2087	18575	-1.859	-0.3815	Yes
128	RFC5	13005 7791	18606	-3.043	-0.2396	Yes
129	NP	22027 9597 5273 5274	18615	-5.092	0.0001	Yes