Details for gene set REACTOME_INITIAL_TRIGGERING_OF

Table: GSEA Results Summary

Dataset	Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB
Phenotype	phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB
Upregulated in class	DMproB
GeneSet	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
Enrichment Score (ES)	0.90908957
Normalized Enrichment Score (NES)	1.4864451
Nominal p-value	0.024948025
FDR q-value	0.6921043
FWER p-Value	1.0

Fig 1: Enrichment plot: REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C3	22915	43	1.780	0.9091	Yes
2	C1QB	8667	1672	0.095	0.8702	No
3	C1QC	15706	3147	0.029	0.8056	No
4	C2	23013	4215	0.014	0.7556	No
5	C1R	11942 6951 6952	7916	0.002	0.5577	No
6	CFD	19957	8368	0.001	0.5340	No
7	C1S	6950 6949	9942	-0.002	0.4503	No
8	C1QA	8666	13039	-0.009	0.2883	No
9	MASP1	1632 22626	13328	-0.010	0.2779	No
10	MBL2	23886	13768	-0.012	0.2605	No

Fig 2: REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT: Random ES distribution
Gene set null distribution of ES for REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT