Details for gene set MAPKKK_CASCADE_GO

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	MAPKKK_CASCADE_GO_0000165
Enrichment Score (ES)	-0.6765322
Normalized Enrichment Score (NES)	-1.5369203
Nominal p-value	0.0
FDR q-value	0.3432743
FWER p-Value	0.93

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ADRA2C	16869	376	1.600	0.0369	No
2	PIK3CB	19030	713	1.094	0.0579	No
3	SOD1	9846	1158	0.738	0.0603	No
4	MAPK8	6459	1918	0.379	0.0328	No
5	PKN1	11567 6799	2353	0.251	0.0184	No
6	TRAF7	10325	2978	0.114	-0.0112	No
7	DAXX	23290	3036	0.104	-0.0106	No
8	RGS3	2434 2474 6937 11935 2374 2332 2445 2390	3960	0.042	-0.0589	No
9	SHC1	9813 9812 5430	3966	0.042	-0.0577	No
10	SPRED2	8539 4332	4259	0.033	-0.0722	No
11	CAMKK2	9870	4758	0.024	-0.0982	No
12	MDFI	22950	4787	0.024	-0.0989	No
13	FGF13	4720 8963 2627	5022	0.021	-0.1108	No
14	MAP3K9	6872	5039	0.021	-0.1109	No
15	MAP3K13	22814	5229	0.019	-0.1205	No
16	GRM4	332	5287	0.018	-0.1229	No
17	GPS1	1392 9943 5550 9944	5603	0.015	-0.1394	No
18	PROK2	17057	5634	0.015	-0.1404	No
19	FGFR3	8969 3566	6077	0.012	-0.1639	No
20	SPRED1	4331	6238	0.011	-0.1721	No
21	ADRA2A	4355	6724	0.009	-0.1980	No
22	C5AR1	17957	7292	0.007	-0.2283	No
23	NRTN	22923	7347	0.007	-0.2310	No
24	TAOK2	10610 3794	7578	0.006	-0.2432	No
25	PAK1	9527	7592	0.006	-0.2437	No
26	ADRB3	18901	7884	0.005	-0.2592	No
27	ATP6AP2	2567 24380 2579 2656	7947	0.005	-0.2624	No
28	MAP3K10	3831 17916	8050	0.004	-0.2678	No
29	GNG3	23752	8072	0.004	-0.2687	No
30	MAP3K7IP1	2193 2171 22419	8369	0.004	-0.2846	No
31	DUSP22	466 21680	8572	0.003	-0.2954	No
32	MBIP	21063 2072	8583	0.003	-0.2958	No
33	MAP2K7	6453	8614	0.003	-0.2973	No
34	MAP3K6	16054	8853	0.003	-0.3101	No
35	ADORA2B	20850	8923	0.002	-0.3137	No
36	EDA2R	6364	9593	0.001	-0.3498	No
37	CHRNA7	17808	9599	0.001	-0.3500	No
38	MINK1	20802	9865	0.000	-0.3643	No
39	DUSP9	24307	10373	-0.001	-0.3917	No
40	EPGN	16798	10442	-0.001	-0.3953	No
41	HIPK2	17180	10830	-0.002	-0.4161	No
42	SCG2	5410 14425	11138	-0.003	-0.4326	No
43	MAPK8IP3	11402 23080	11152	-0.003	-0.4332	No
44	GHRL	1183 17040	11284	-0.003	-0.4401	No
45	FPR1	23115	11300	-0.003	-0.4408	No
46	PLCE1	13156	11373	-0.004	-0.4446	No
47	MAP3K12	6454 11164	11464	-0.004	-0.4493	No
48	TDGF1	5704 10108	11624	-0.004	-0.4577	No
49	TGFA	17381	12092	-0.006	-0.4827	No
50	EGF	15169	12130	-0.006	-0.4845	No
51	RGS4	9724	12233	-0.007	-0.4897	No
52	DUSP16	1004 7699	12672	-0.009	-0.5131	No
53	MADD	2926 14526	13136	-0.011	-0.5377	No
54	FGFR1	3789 8968	13224	-0.012	-0.5420	No
55	MAP3K5	20079 11166	13358	-0.013	-0.5487	No
56	MAPK10	11169	13577	-0.014	-0.5599	No
57	MAPK8IP2	77	13813	-0.017	-0.5720	No
58	MAP3K4	23126	13828	-0.017	-0.5722	No
59	CD27	16994	14292	-0.024	-0.5963	No
60	DUSP4	18632 3820	14677	-0.034	-0.6158	No
61	TPD52L1	3420 19793	14978	-0.045	-0.6304	No
62	MAP4K5	11853 21048 2101 2142	15067	-0.049	-0.6334	No
63	DUSP8	9493	15134	-0.052	-0.6351	No
64	FGF2	15608	15175	-0.054	-0.6353	No
65	MAP3K2	11165	15499	-0.077	-0.6500	No
66	NF1	5165	15715	-0.100	-0.6580	No
67	CARTPT	21374	15862	-0.123	-0.6615	No
68	SH2D3C	2864	15941	-0.134	-0.6609	No
69	MAP4K3	22887	16032	-0.154	-0.6603	No
70	MAP4K2	6457	16334	-0.224	-0.6685	Yes
71	EDG5	19216	16428	-0.252	-0.6645	Yes
72	CD24	8711	16453	-0.262	-0.6565	Yes
73	MAP4K1	18313	16615	-0.312	-0.6540	Yes
74	MAP2K4	20405	16842	-0.384	-0.6525	Yes
75	GADD45G	21637	16864	-0.392	-0.6396	Yes
76	DBNL	20954	17191	-0.523	-0.6386	Yes
77	GPS2	12096	17275	-0.564	-0.6229	Yes
78	CRKL	4560	17368	-0.613	-0.6060	Yes
79	GADD45B	19935	17372	-0.615	-0.5841	Yes
80	DUSP10	4003 14016	17441	-0.668	-0.5639	Yes
81	CD81	8719	17641	-0.785	-0.5466	Yes
82	ADRB2	23422	17695	-0.828	-0.5199	Yes
83	MAP3K11	11163	17905	-1.013	-0.4949	Yes
84	MAP3K3	20626	17998	-1.103	-0.4605	Yes
85	CCM2	20950	18223	-1.441	-0.4211	Yes
86	MAPKAPK2	13838	18261	-1.536	-0.3682	Yes
87	MAPK9	1233 20903 1383	18352	-1.775	-0.3096	Yes
88	DUSP2	14865	18415	-1.980	-0.2422	Yes
89	CXCR4	13844	18494	-2.475	-0.1579	Yes
90	DUSP6	19891 3399	18594	-4.601	0.0012	Yes