Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | DNA_DEPENDENT_DNA_REPLICATION |
| Enrichment Score (ES) | 0.8248112 |
| Normalized Enrichment Score (NES) | 1.6308552 |
| Nominal p-value | 0.003552398 |
| FDR q-value | 0.041412927 |
| FWER p-Value | 0.192 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TIPIN | 3013 7258 | 380 | 1.595 | 0.0601 | Yes | ||
| 2 | RFC4 | 1735 22627 | 460 | 1.437 | 0.1284 | Yes | ||
| 3 | MSH2 | 23138 | 480 | 1.403 | 0.1982 | Yes | ||
| 4 | MSH6 | 23137 5120 | 483 | 1.397 | 0.2686 | Yes | ||
| 5 | RFC1 | 16527 | 604 | 1.237 | 0.3247 | Yes | ||
| 6 | GTPBP4 | 21548 | 620 | 1.216 | 0.3853 | Yes | ||
| 7 | ATR | 19349 | 729 | 1.081 | 0.4340 | Yes | ||
| 8 | MCM3 | 13991 | 732 | 1.080 | 0.4885 | Yes | ||
| 9 | MLH1 | 18982 | 792 | 1.025 | 0.5370 | Yes | ||
| 10 | RFC3 | 12786 | 1080 | 0.786 | 0.5613 | Yes | ||
| 11 | RPA1 | 20349 | 1100 | 0.775 | 0.5994 | Yes | ||
| 12 | PRIM1 | 19847 | 1166 | 0.734 | 0.6330 | Yes | ||
| 13 | GMNN | 21513 | 1199 | 0.713 | 0.6673 | Yes | ||
| 14 | ORC5L | 11173 3595 | 1270 | 0.664 | 0.6970 | Yes | ||
| 15 | PMS2 | 16632 | 1433 | 0.574 | 0.7173 | Yes | ||
| 16 | MUTYH | 2400 7693 | 1629 | 0.488 | 0.7314 | Yes | ||
| 17 | CDT1 | 18437 | 1711 | 0.452 | 0.7499 | Yes | ||
| 18 | CDK2AP1 | 8858 | 1819 | 0.413 | 0.7650 | Yes | ||
| 19 | S100A11 | 9771 | 1869 | 0.394 | 0.7822 | Yes | ||
| 20 | RPA2 | 2330 16057 | 1910 | 0.383 | 0.7994 | Yes | ||
| 21 | POLG2 | 20180 | 1935 | 0.373 | 0.8170 | Yes | ||
| 22 | CDK2 | 3438 3373 19592 3322 | 2093 | 0.323 | 0.8248 | Yes | ||
| 23 | MSH3 | 5119 | 2868 | 0.133 | 0.7898 | No | ||
| 24 | MSH5 | 23010 1599 | 3034 | 0.104 | 0.7862 | No | ||
| 25 | RAD51 | 2897 14903 | 3745 | 0.050 | 0.7505 | No | ||
| 26 | ORC4L | 11172 6460 | 4060 | 0.039 | 0.7356 | No | ||
| 27 | GLI2 | 13859 | 4273 | 0.033 | 0.7258 | No | ||
| 28 | RAD17 | 21366 | 4304 | 0.033 | 0.7259 | No | ||
| 29 | PMS1 | 13958 | 4371 | 0.031 | 0.7239 | No | ||
| 30 | NF2 | 1222 5166 | 6074 | 0.012 | 0.6328 | No | ||
| 31 | CDC6 | 6221 6220 | 6131 | 0.012 | 0.6304 | No | ||
| 32 | NBN | 2485 16268 2408 | 6169 | 0.011 | 0.6290 | No | ||
| 33 | TFAM | 19739 3330 | 6622 | 0.009 | 0.6051 | No | ||
| 34 | POLA1 | 24112 | 9841 | 0.000 | 0.4318 | No | ||
| 35 | CDC45L | 22642 1752 | 9951 | -0.000 | 0.4260 | No | ||
| 36 | PURA | 9670 | 10425 | -0.001 | 0.4005 | No | ||
| 37 | EREG | 4679 16797 | 10638 | -0.002 | 0.3892 | No | ||
| 38 | GLI1 | 19605 | 11157 | -0.003 | 0.3615 | No | ||
| 39 | HMGB2 | 13594 | 11501 | -0.004 | 0.3432 | No | ||
| 40 | WRNIP1 | 21675 3161 | 13438 | -0.013 | 0.2396 | No | ||
| 41 | ABL1 | 2693 4301 2794 | 14038 | -0.020 | 0.2083 | No | ||
| 42 | ORC2L | 385 13949 | 14723 | -0.036 | 0.1733 | No | ||
| 43 | RAD9A | 913 3674 910 23958 | 14774 | -0.037 | 0.1725 | No | ||
| 44 | EXO1 | 14035 4135 | 15469 | -0.074 | 0.1389 | No | ||
| 45 | ORC1L | 327 16144 | 15780 | -0.109 | 0.1277 | No | ||
| 46 | REV3L | 20050 | 16044 | -0.156 | 0.1214 | No | ||
| 47 | POLB | 9599 | 16694 | -0.338 | 0.1035 | No |
