Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | V$OCT1_B |
Enrichment Score (ES) | -0.6722241 |
Normalized Enrichment Score (NES) | -1.6381304 |
Nominal p-value | 0.0 |
FDR q-value | 0.038995937 |
FWER p-Value | 0.129 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SERTAD4 | 13715 | 141 | 2.456 | 0.0364 | No | ||
2 | BLNK | 23681 3691 | 325 | 1.702 | 0.0569 | No | ||
3 | PPARGC1B | 9318 | 1044 | 0.811 | 0.0325 | No | ||
4 | CD86 | 1660 22601 | 1048 | 0.807 | 0.0468 | No | ||
5 | PIM2 | 5249 9564 9565 | 1501 | 0.544 | 0.0320 | No | ||
6 | NR1D1 | 4650 20258 949 | 1638 | 0.483 | 0.0333 | No | ||
7 | E2F3 | 21500 8874 | 1906 | 0.383 | 0.0257 | No | ||
8 | CDK2 | 3438 3373 19592 3322 | 2093 | 0.323 | 0.0214 | No | ||
9 | SRF | 22961 1597 | 2181 | 0.296 | 0.0219 | No | ||
10 | ATF7IP | 12028 13038 | 2434 | 0.228 | 0.0123 | No | ||
11 | TSGA14 | 17194 | 2614 | 0.187 | 0.0060 | No | ||
12 | TBR1 | 83 | 2761 | 0.152 | 0.0008 | No | ||
13 | HIST2H2AC | 6650 | 2898 | 0.127 | -0.0043 | No | ||
14 | IFIT2 | 23880 | 3021 | 0.106 | -0.0091 | No | ||
15 | NR6A1 | 14596 | 3057 | 0.101 | -0.0091 | No | ||
16 | TWIST1 | 21291 | 3422 | 0.067 | -0.0277 | No | ||
17 | UBE2S | 17979 | 3491 | 0.063 | -0.0303 | No | ||
18 | EAF2 | 1727 8383 | 3595 | 0.058 | -0.0348 | No | ||
19 | TMOD2 | 6946 | 3868 | 0.045 | -0.0488 | No | ||
20 | BCDO2 | 19124 | 3891 | 0.044 | -0.0492 | No | ||
21 | CDH13 | 4506 3826 | 4251 | 0.034 | -0.0680 | No | ||
22 | LRRTM4 | 17405 | 4257 | 0.034 | -0.0677 | No | ||
23 | OLIG3 | 20084 | 4358 | 0.031 | -0.0726 | No | ||
24 | SFRP2 | 15564 | 4379 | 0.031 | -0.0731 | No | ||
25 | COL25A1 | 8056 1837 1844 1915 13376 | 4385 | 0.030 | -0.0728 | No | ||
26 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 4399 | 0.030 | -0.0730 | No | ||
27 | FES | 17779 3949 | 4419 | 0.030 | -0.0735 | No | ||
28 | PTHLH | 16931 | 4478 | 0.029 | -0.0761 | No | ||
29 | VSNL1 | 6527 | 4615 | 0.026 | -0.0830 | No | ||
30 | POU3F4 | 347 | 4630 | 0.026 | -0.0833 | No | ||
31 | SCOC | 3821 12106 | 4653 | 0.026 | -0.0841 | No | ||
32 | HOXA10 | 17145 989 | 4684 | 0.025 | -0.0853 | No | ||
33 | SOX2 | 9849 15612 | 4695 | 0.025 | -0.0854 | No | ||
34 | DLGAP4 | 2950 10461 | 4722 | 0.025 | -0.0863 | No | ||
35 | LHX6 | 9275 2914 | 5012 | 0.021 | -0.1016 | No | ||
36 | MGAT5B | 20584 11197 | 5065 | 0.020 | -0.1041 | No | ||
37 | HOXA13 | 9107 | 5078 | 0.020 | -0.1044 | No | ||
38 | LRCH4 | 10544 6090 | 5122 | 0.020 | -0.1064 | No | ||
39 | CDX2 | 16289 | 5123 | 0.020 | -0.1060 | No | ||
40 | THRA | 1447 10171 1406 | 5128 | 0.020 | -0.1059 | No | ||
41 | WNT6 | 5881 | 5282 | 0.018 | -0.1138 | No | ||
42 | TCF2 | 1395 20727 | 5297 | 0.018 | -0.1143 | No | ||
43 | NEUROD6 | 17138 | 5322 | 0.018 | -0.1153 | No | ||
44 | CDX4 | 24273 | 5722 | 0.014 | -0.1367 | No | ||
45 | CPD | 20344 4556 | 5731 | 0.014 | -0.1368 | No | ||
46 | MID1 | 5097 5098 | 5769 | 0.014 | -0.1386 | No | ||
47 | BDNF | 14926 2797 | 5772 | 0.014 | -0.1385 | No | ||
48 | CRYZL1 | 1644 12385 | 5864 | 0.013 | -0.1432 | No | ||
49 | RGL1 | 9723 4072 | 5901 | 0.013 | -0.1449 | No | ||
50 | SLC19A3 | 8152 | 5903 | 0.013 | -0.1447 | No | ||
51 | HOXB6 | 20688 | 6007 | 0.012 | -0.1501 | No | ||
52 | NRL | 9484 | 6224 | 0.011 | -0.1616 | No | ||
53 | RRM2B | 6902 6903 11801 | 6266 | 0.011 | -0.1636 | No | ||
54 | ALDH1A1 | 8569 | 6357 | 0.011 | -0.1683 | No | ||
55 | DNAH5 | 8470 | 6457 | 0.010 | -0.1735 | No | ||
56 | CYR61 | 9159 15145 9311 5024 | 6698 | 0.009 | -0.1864 | No | ||
57 | NRAS | 5191 | 6782 | 0.009 | -0.1907 | No | ||
58 | IRX4 | 11944 | 6816 | 0.009 | -0.1924 | No | ||
59 | KLF12 | 4960 2637 21732 9228 | 7088 | 0.008 | -0.2069 | No | ||
60 | SILV | 16130 | 7154 | 0.007 | -0.2103 | No | ||
61 | SLC1A2 | 5453 | 7240 | 0.007 | -0.2148 | No | ||
62 | PCYT1B | 24289 | 7399 | 0.006 | -0.2233 | No | ||
63 | LPL | 9283 5003 | 7566 | 0.006 | -0.2322 | No | ||
64 | STAG1 | 5520 9905 2987 | 7662 | 0.006 | -0.2372 | No | ||
65 | EPHB3 | 22816 | 8009 | 0.005 | -0.2559 | No | ||
66 | FBXO24 | 12918 3649 | 8109 | 0.004 | -0.2612 | No | ||
67 | PCDH20 | 5780 | 8317 | 0.004 | -0.2724 | No | ||
68 | LIPG | 23407 | 8383 | 0.004 | -0.2758 | No | ||
69 | FSTL5 | 10018 | 8527 | 0.003 | -0.2835 | No | ||
70 | MBIP | 21063 2072 | 8583 | 0.003 | -0.2865 | No | ||
71 | PRKG1 | 5289 | 8607 | 0.003 | -0.2877 | No | ||
72 | ITSN1 | 9196 | 8677 | 0.003 | -0.2913 | No | ||
73 | TBXAS1 | 17480 1105 | 8699 | 0.003 | -0.2924 | No | ||
74 | ALK | 8574 | 8963 | 0.002 | -0.3067 | No | ||
75 | FGF14 | 21716 3005 3463 | 9074 | 0.002 | -0.3126 | No | ||
76 | NRXN3 | 2153 5196 | 9167 | 0.002 | -0.3176 | No | ||
77 | FGF12 | 1723 22621 | 9207 | 0.002 | -0.3196 | No | ||
78 | SLC6A15 | 8335 3321 | 9210 | 0.002 | -0.3197 | No | ||
79 | PAX6 | 5223 | 9241 | 0.002 | -0.3213 | No | ||
80 | PRRX1 | 9595 5271 | 9264 | 0.002 | -0.3225 | No | ||
81 | ADORA2A | 8557 | 9558 | 0.001 | -0.3384 | No | ||
82 | GNB3 | 9027 | 9671 | 0.001 | -0.3444 | No | ||
83 | NXPH1 | 17524 | 9696 | 0.001 | -0.3457 | No | ||
84 | UPK3A | 22401 | 9731 | 0.000 | -0.3476 | No | ||
85 | TSC1 | 7235 | 9972 | -0.000 | -0.3606 | No | ||
86 | PRDM1 | 19775 3337 | 9987 | -0.000 | -0.3613 | No | ||
87 | NFIA | 16172 5170 | 10033 | -0.000 | -0.3638 | No | ||
88 | SYNPR | 22094 | 10205 | -0.001 | -0.3731 | No | ||
89 | LYN | 16281 | 10463 | -0.001 | -0.3870 | No | ||
90 | EHF | 4657 | 10541 | -0.001 | -0.3911 | No | ||
91 | RGS13 | 13811 | 10617 | -0.002 | -0.3952 | No | ||
92 | CNNM4 | 14273 | 10721 | -0.002 | -0.4007 | No | ||
93 | TCEAL1 | 24245 | 11044 | -0.003 | -0.4181 | No | ||
94 | SKIL | 15617 | 11169 | -0.003 | -0.4248 | No | ||
95 | SLC24A1 | 19080 | 11192 | -0.003 | -0.4260 | No | ||
96 | MRAS | 9409 | 11204 | -0.003 | -0.4265 | No | ||
97 | HOXC5 | 22340 | 11403 | -0.004 | -0.4372 | No | ||
98 | MITF | 17349 | 11903 | -0.005 | -0.4641 | No | ||
99 | CSF3 | 1394 20671 | 11910 | -0.005 | -0.4644 | No | ||
100 | GPR4 | 18364 | 12216 | -0.006 | -0.4808 | No | ||
101 | SATB2 | 5604 | 12242 | -0.007 | -0.4821 | No | ||
102 | KIF13A | 21475 | 12291 | -0.007 | -0.4845 | No | ||
103 | GPC4 | 24153 | 12456 | -0.007 | -0.4933 | No | ||
104 | POU2F3 | 9602 | 12487 | -0.008 | -0.4948 | No | ||
105 | CLCA3 | 6224 | 12491 | -0.008 | -0.4948 | No | ||
106 | CRISP1 | 22980 | 12499 | -0.008 | -0.4951 | No | ||
107 | SPRR2B | 9869 | 12546 | -0.008 | -0.4974 | No | ||
108 | GAB2 | 1821 18184 2025 | 12547 | -0.008 | -0.4973 | No | ||
109 | OTX2 | 9519 | 12558 | -0.008 | -0.4977 | No | ||
110 | SH3GL3 | 18201 | 12586 | -0.008 | -0.4990 | No | ||
111 | GUCA1A | 22952 | 12661 | -0.009 | -0.5028 | No | ||
112 | NRXN1 | 1581 1575 22875 | 12680 | -0.009 | -0.5037 | No | ||
113 | DPYSL3 | 10252 | 12751 | -0.009 | -0.5073 | No | ||
114 | LDB2 | 16538 4989 | 12848 | -0.009 | -0.5124 | No | ||
115 | HIST1H2AC | 6648 | 13176 | -0.011 | -0.5299 | No | ||
116 | LRRN1 | 17343 | 13347 | -0.012 | -0.5389 | No | ||
117 | SLITRK6 | 21724 | 13361 | -0.013 | -0.5394 | No | ||
118 | HPCAL4 | 16096 | 13472 | -0.013 | -0.5451 | No | ||
119 | KCTD6 | 22098 | 13505 | -0.014 | -0.5466 | No | ||
120 | CSMD3 | 10735 7938 | 13543 | -0.014 | -0.5484 | No | ||
121 | ASCL3 | 17681 | 13559 | -0.014 | -0.5489 | No | ||
122 | ADORA1 | 13831 | 13767 | -0.016 | -0.5598 | No | ||
123 | SP6 | 8178 13678 13679 | 13861 | -0.017 | -0.5646 | No | ||
124 | PIPOX | 20340 | 13990 | -0.019 | -0.5712 | No | ||
125 | PFKFB1 | 9552 | 14050 | -0.020 | -0.5740 | No | ||
126 | TLL2 | 23680 | 14268 | -0.024 | -0.5854 | No | ||
127 | NEUROG1 | 21446 | 14365 | -0.026 | -0.5901 | No | ||
128 | COL23A1 | 10696 | 14369 | -0.026 | -0.5898 | No | ||
129 | GPRC5B | 17662 | 14397 | -0.027 | -0.5908 | No | ||
130 | RAB26 | 11609 | 14436 | -0.027 | -0.5924 | No | ||
131 | KCNN3 | 15538 1913 | 14503 | -0.029 | -0.5955 | No | ||
132 | DMD | 24295 2647 | 14603 | -0.032 | -0.6003 | No | ||
133 | TRPM1 | 10846 474 9395 494 | 14698 | -0.035 | -0.6047 | No | ||
134 | GPM6A | 3834 10618 | 14786 | -0.038 | -0.6088 | No | ||
135 | FZD2 | 12179 | 14945 | -0.044 | -0.6166 | No | ||
136 | STAT4 | 14251 9907 | 14999 | -0.046 | -0.6186 | No | ||
137 | NR2C2 | 10216 | 15055 | -0.049 | -0.6207 | No | ||
138 | ETV1 | 4688 8925 8924 | 15435 | -0.071 | -0.6400 | No | ||
139 | HDAC9 | 21084 2131 | 15520 | -0.080 | -0.6432 | No | ||
140 | SESN3 | 19561 | 15766 | -0.106 | -0.6546 | No | ||
141 | PDE4D | 10722 6235 | 15879 | -0.126 | -0.6584 | No | ||
142 | EGR2 | 8886 | 15952 | -0.137 | -0.6598 | No | ||
143 | REL | 9716 | 16118 | -0.172 | -0.6657 | No | ||
144 | NEDD4 | 19384 3101 | 16132 | -0.175 | -0.6633 | No | ||
145 | BAT2 | 23006 | 16298 | -0.215 | -0.6684 | Yes | ||
146 | NDNL2 | 17804 | 16300 | -0.215 | -0.6646 | Yes | ||
147 | HIST1H2AH | 11414 | 16314 | -0.219 | -0.6613 | Yes | ||
148 | SREBF2 | 5509 | 16478 | -0.269 | -0.6654 | Yes | ||
149 | PIK3CD | 9563 | 16569 | -0.297 | -0.6649 | Yes | ||
150 | BIN3 | 21969 | 16643 | -0.323 | -0.6631 | Yes | ||
151 | GFI1B | 14637 | 16687 | -0.336 | -0.6594 | Yes | ||
152 | ITPR3 | 9195 | 16697 | -0.339 | -0.6538 | Yes | ||
153 | POLM | 20538 | 16741 | -0.353 | -0.6498 | Yes | ||
154 | HIST1H3C | 13633 | 16832 | -0.382 | -0.6479 | Yes | ||
155 | MAP2K6 | 20614 1414 | 16879 | -0.397 | -0.6433 | Yes | ||
156 | H3F3B | 4839 | 16884 | -0.398 | -0.6364 | Yes | ||
157 | SLC25A12 | 14562 | 16957 | -0.427 | -0.6326 | Yes | ||
158 | CSNK1E | 6570 2211 11332 | 17171 | -0.518 | -0.6349 | Yes | ||
159 | HIST1H2AB | 13652 | 17181 | -0.520 | -0.6260 | Yes | ||
160 | SH3BGRL | 24267 | 17229 | -0.536 | -0.6190 | Yes | ||
161 | KCTD12 | 6240 | 17251 | -0.549 | -0.6103 | Yes | ||
162 | ZHX2 | 11842 | 17361 | -0.610 | -0.6053 | Yes | ||
163 | RHOB | 4411 | 17502 | -0.704 | -0.6002 | Yes | ||
164 | THRAP5 | 19701 | 17552 | -0.732 | -0.5898 | Yes | ||
165 | NFYB | 5173 | 17579 | -0.746 | -0.5778 | Yes | ||
166 | BTK | 24061 | 17622 | -0.771 | -0.5663 | Yes | ||
167 | SCML4 | 20042 | 17625 | -0.772 | -0.5526 | Yes | ||
168 | AXUD1 | 18967 | 17724 | -0.855 | -0.5426 | Yes | ||
169 | ESRRA | 23802 | 17796 | -0.905 | -0.5302 | Yes | ||
170 | RRAS | 18256 | 17955 | -1.064 | -0.5197 | Yes | ||
171 | NOTCH1 | 14649 | 17966 | -1.076 | -0.5010 | Yes | ||
172 | PTEN | 5305 | 18017 | -1.128 | -0.4835 | Yes | ||
173 | CD79B | 20185 1309 | 18046 | -1.168 | -0.4641 | Yes | ||
174 | FOXP1 | 4242 | 18090 | -1.220 | -0.4445 | Yes | ||
175 | HIST1H2BB | 11417 | 18186 | -1.368 | -0.4252 | Yes | ||
176 | TCF12 | 10044 3125 | 18187 | -1.373 | -0.4006 | Yes | ||
177 | HIST2H2BE | 6651 | 18242 | -1.490 | -0.3768 | Yes | ||
178 | HIST1H3B | 11406 | 18251 | -1.520 | -0.3500 | Yes | ||
179 | ARHGAP4 | 9343 | 18265 | -1.543 | -0.3231 | Yes | ||
180 | VPREB3 | 19984 | 18278 | -1.583 | -0.2954 | Yes | ||
181 | HIST1H2BC | 12625 21696 | 18337 | -1.747 | -0.2672 | Yes | ||
182 | ACBD4 | 20637 | 18363 | -1.814 | -0.2361 | Yes | ||
183 | HIST1H2BK | 11423 | 18384 | -1.888 | -0.2033 | Yes | ||
184 | RHOBTB2 | 3069 6373 10902 | 18425 | -2.033 | -0.1690 | Yes | ||
185 | HIST1H2BM | 11425 | 18466 | -2.279 | -0.1304 | Yes | ||
186 | ARPC5 | 12580 7487 | 18557 | -3.122 | -0.0793 | Yes | ||
187 | DUSP6 | 19891 3399 | 18594 | -4.601 | 0.0012 | Yes |