Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | V$NRF1_Q6 |
Enrichment Score (ES) | 0.5637117 |
Normalized Enrichment Score (NES) | 1.3091643 |
Nominal p-value | 0.027538726 |
FDR q-value | 0.8394704 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CBFB | 3769 18499 | 5 | 5.904 | 0.0944 | Yes | ||
2 | RAB18 | 1972 5342 | 106 | 2.576 | 0.1303 | Yes | ||
3 | SHMT2 | 3307 19601 | 188 | 2.155 | 0.1605 | Yes | ||
4 | AFG3L1 | 8547 4342 18427 3865 | 226 | 2.051 | 0.1914 | Yes | ||
5 | CCT3 | 8709 | 248 | 1.945 | 0.2214 | Yes | ||
6 | ALG8 | 11779 3912 2277 | 278 | 1.852 | 0.2496 | Yes | ||
7 | EXOSC5 | 18334 | 410 | 1.520 | 0.2669 | Yes | ||
8 | MRPS18B | 7365 | 414 | 1.514 | 0.2910 | Yes | ||
9 | EIF5A | 11345 20379 6590 | 438 | 1.466 | 0.3133 | Yes | ||
10 | FGFR1OP2 | 12544 12543 7457 | 486 | 1.393 | 0.3331 | Yes | ||
11 | MRPL22 | 10111 | 508 | 1.365 | 0.3538 | Yes | ||
12 | PLOD3 | 16666 | 516 | 1.353 | 0.3751 | Yes | ||
13 | ENDOGL1 | 3115 19275 | 559 | 1.313 | 0.3939 | Yes | ||
14 | XRCC1 | 173 | 651 | 1.174 | 0.4078 | Yes | ||
15 | PRKRIR | 7834 | 727 | 1.082 | 0.4211 | Yes | ||
16 | DNMT1 | 19217 | 812 | 1.012 | 0.4328 | Yes | ||
17 | RQCD1 | 12205 | 830 | 0.995 | 0.4478 | Yes | ||
18 | SSBP4 | 13368 | 850 | 0.969 | 0.4623 | Yes | ||
19 | XPO5 | 7802 | 936 | 0.894 | 0.4721 | Yes | ||
20 | TUBG1 | 20662 | 1029 | 0.824 | 0.4803 | Yes | ||
21 | POLA2 | 23988 | 1088 | 0.782 | 0.4897 | Yes | ||
22 | FUS | 6135 | 1132 | 0.754 | 0.4995 | Yes | ||
23 | PSMA4 | 11179 | 1233 | 0.690 | 0.5051 | Yes | ||
24 | ARRB2 | 20806 | 1508 | 0.540 | 0.4990 | Yes | ||
25 | SNRP70 | 1186 | 1537 | 0.531 | 0.5060 | Yes | ||
26 | MAGED1 | 24108 | 1593 | 0.505 | 0.5111 | Yes | ||
27 | TRIM28 | 18389 | 1689 | 0.462 | 0.5133 | Yes | ||
28 | ZNHIT1 | 16334 | 1755 | 0.436 | 0.5168 | Yes | ||
29 | MAGED2 | 24034 | 1792 | 0.422 | 0.5216 | Yes | ||
30 | GTF2F1 | 13599 | 1799 | 0.419 | 0.5280 | Yes | ||
31 | RAB10 | 2090 21119 | 1805 | 0.417 | 0.5345 | Yes | ||
32 | BAT3 | 5896 | 1884 | 0.389 | 0.5365 | Yes | ||
33 | YWHAE | 20776 | 1991 | 0.354 | 0.5364 | Yes | ||
34 | GPSN2 | 18823 3868 | 2033 | 0.343 | 0.5397 | Yes | ||
35 | TTLL4 | 328 | 2150 | 0.304 | 0.5383 | Yes | ||
36 | CFL1 | 4516 | 2158 | 0.303 | 0.5428 | Yes | ||
37 | PREB | 6948 3628 | 2167 | 0.300 | 0.5472 | Yes | ||
38 | POP7 | 16329 | 2251 | 0.275 | 0.5471 | Yes | ||
39 | SFRS1 | 8492 | 2269 | 0.270 | 0.5505 | Yes | ||
40 | NEK8 | 20338 | 2281 | 0.267 | 0.5542 | Yes | ||
41 | USP37 | 13923 | 2297 | 0.264 | 0.5576 | Yes | ||
42 | PPP1R12A | 3354 19886 | 2373 | 0.244 | 0.5574 | Yes | ||
43 | THEM2 | 21512 | 2374 | 0.244 | 0.5614 | Yes | ||
44 | SFRS9 | 16731 | 2448 | 0.225 | 0.5610 | Yes | ||
45 | SFRS7 | 22889 | 2474 | 0.218 | 0.5632 | Yes | ||
46 | NDUFB8 | 7418 | 2579 | 0.196 | 0.5607 | Yes | ||
47 | SPATA5L1 | 10062 | 2598 | 0.192 | 0.5628 | Yes | ||
48 | HNRPL | 18315 | 2660 | 0.177 | 0.5623 | Yes | ||
49 | SUFU | 6283 | 2730 | 0.159 | 0.5611 | Yes | ||
50 | MIB1 | 5908 | 2771 | 0.150 | 0.5614 | Yes | ||
51 | SNX12 | 7061 | 2773 | 0.150 | 0.5637 | Yes | ||
52 | PPP1R10 | 6972 11960 6971 | 2878 | 0.131 | 0.5602 | No | ||
53 | SLC39A7 | 23022 | 2887 | 0.130 | 0.5618 | No | ||
54 | MAPT | 9420 1347 | 2993 | 0.112 | 0.5579 | No | ||
55 | PAQR4 | 23105 | 3055 | 0.102 | 0.5563 | No | ||
56 | HOXC4 | 4864 | 3198 | 0.085 | 0.5500 | No | ||
57 | CLGN | 4528 | 3260 | 0.081 | 0.5479 | No | ||
58 | POLH | 22966 | 3418 | 0.067 | 0.5405 | No | ||
59 | VAV3 | 1774 1848 15443 | 3728 | 0.051 | 0.5246 | No | ||
60 | MPDU1 | 20386 | 3797 | 0.048 | 0.5217 | No | ||
61 | BCKDHA | 17925 | 4307 | 0.032 | 0.4947 | No | ||
62 | SYNGR4 | 17825 | 4370 | 0.031 | 0.4918 | No | ||
63 | GABRB1 | 16832 | 4427 | 0.030 | 0.4892 | No | ||
64 | CNTNAP1 | 11987 | 4446 | 0.029 | 0.4887 | No | ||
65 | HMMR | 20493 1243 | 4564 | 0.027 | 0.4828 | No | ||
66 | MPP5 | 21230 7078 | 4694 | 0.025 | 0.4763 | No | ||
67 | EIF2S1 | 4658 | 4978 | 0.021 | 0.4613 | No | ||
68 | ACCN2 | 22363 | 5430 | 0.017 | 0.4371 | No | ||
69 | PARK2 | 6944 11939 1499 23385 | 5749 | 0.014 | 0.4201 | No | ||
70 | RAGE | 6465 2056 2165 | 5787 | 0.014 | 0.4183 | No | ||
71 | SPRY4 | 23448 | 5967 | 0.013 | 0.4089 | No | ||
72 | FMR1 | 24321 | 6850 | 0.008 | 0.3612 | No | ||
73 | KCNK5 | 4946 9212 | 6875 | 0.008 | 0.3601 | No | ||
74 | FNBP4 | 14956 2671 | 7289 | 0.007 | 0.3378 | No | ||
75 | HIP2 | 3626 3485 16838 | 7406 | 0.006 | 0.3317 | No | ||
76 | DNAJC3 | 21934 | 7480 | 0.006 | 0.3278 | No | ||
77 | STX12 | 4140 | 7624 | 0.006 | 0.3201 | No | ||
78 | RHOA | 8624 4409 4410 | 8262 | 0.004 | 0.2857 | No | ||
79 | PTPN2 | 23414 | 8307 | 0.004 | 0.2834 | No | ||
80 | PHC3 | 6313 | 8446 | 0.003 | 0.2760 | No | ||
81 | UXS1 | 13965 | 8562 | 0.003 | 0.2698 | No | ||
82 | MAP2K7 | 6453 | 8614 | 0.003 | 0.2671 | No | ||
83 | CKS2 | 7264 | 8728 | 0.003 | 0.2610 | No | ||
84 | NNAT | 2764 5180 | 8773 | 0.003 | 0.2587 | No | ||
85 | MAZ | 1327 17623 | 8788 | 0.003 | 0.2580 | No | ||
86 | FGF12 | 1723 22621 | 9207 | 0.002 | 0.2354 | No | ||
87 | DISP2 | 5652 | 9389 | 0.001 | 0.2256 | No | ||
88 | JAG1 | 14415 | 10441 | -0.001 | 0.1687 | No | ||
89 | ADAM10 | 4336 | 10680 | -0.002 | 0.1559 | No | ||
90 | VAT1 | 11253 | 10688 | -0.002 | 0.1555 | No | ||
91 | DNAJA1 | 4878 16242 2345 | 10832 | -0.002 | 0.1478 | No | ||
92 | USF2 | 10262 5833 10263 | 10845 | -0.002 | 0.1472 | No | ||
93 | ABI2 | 4037 6830 | 11433 | -0.004 | 0.1155 | No | ||
94 | SEC14L1 | 1212 20583 | 11528 | -0.004 | 0.1104 | No | ||
95 | LRP1 | 9284 | 11848 | -0.005 | 0.0933 | No | ||
96 | GRIN2B | 16957 | 11902 | -0.005 | 0.0905 | No | ||
97 | WNT5A | 22066 5880 | 12960 | -0.010 | 0.0334 | No | ||
98 | POU4F2 | 9603 5276 | 13020 | -0.010 | 0.0304 | No | ||
99 | BTBD3 | 10457 2975 6007 6006 | 13111 | -0.011 | 0.0257 | No | ||
100 | MLLT7 | 24278 | 13182 | -0.011 | 0.0221 | No | ||
101 | MST1 | 9089 | 13341 | -0.012 | 0.0137 | No | ||
102 | PACRG | 23127 | 13706 | -0.016 | -0.0057 | No | ||
103 | GABRB2 | 20922 | 13838 | -0.017 | -0.0126 | No | ||
104 | HOXC6 | 22339 2302 | 13871 | -0.017 | -0.0140 | No | ||
105 | CRK | 4559 1249 | 14123 | -0.021 | -0.0273 | No | ||
106 | PHF1 | 23324 1551 | 14334 | -0.025 | -0.0382 | No | ||
107 | RNF111 | 13555 8218 13556 | 14659 | -0.033 | -0.0552 | No | ||
108 | TTRAP | 21692 | 14680 | -0.034 | -0.0558 | No | ||
109 | MRPL45 | 20680 | 14708 | -0.035 | -0.0567 | No | ||
110 | CLOCK | 8749 16507 4530 | 14882 | -0.041 | -0.0654 | No | ||
111 | FUT8 | 2163 21233 | 14924 | -0.042 | -0.0669 | No | ||
112 | PCTK1 | 24369 | 14935 | -0.043 | -0.0668 | No | ||
113 | POU2F1 | 5275 3989 4065 4010 | 15053 | -0.048 | -0.0723 | No | ||
114 | JARID1C | 5460 2563 | 15227 | -0.058 | -0.0808 | No | ||
115 | MCRS1 | 6961 6960 6962 | 15323 | -0.063 | -0.0849 | No | ||
116 | RXRB | 23285 9768 | 15372 | -0.067 | -0.0864 | No | ||
117 | CCNI | 4493 | 15600 | -0.086 | -0.0973 | No | ||
118 | SPINT2 | 4128 17899 | 15604 | -0.087 | -0.0961 | No | ||
119 | NF1 | 5165 | 15715 | -0.100 | -0.1005 | No | ||
120 | GOLGA1 | 14595 | 15786 | -0.109 | -0.1025 | No | ||
121 | NFYA | 5172 | 16184 | -0.187 | -0.1210 | No | ||
122 | JMJD2C | 16188 | 16336 | -0.226 | -0.1256 | No | ||
123 | PPP1R15B | 4254 14135 | 16402 | -0.243 | -0.1252 | No | ||
124 | ARFGAP3 | 22183 | 16469 | -0.266 | -0.1245 | No | ||
125 | SEC24C | 22086 | 16595 | -0.305 | -0.1264 | No | ||
126 | MAP4K1 | 18313 | 16615 | -0.312 | -0.1224 | No | ||
127 | U2AF2 | 5813 5812 5814 | 16675 | -0.333 | -0.1202 | No | ||
128 | SRRM1 | 6958 | 16840 | -0.383 | -0.1230 | No | ||
129 | SPOP | 5498 | 16868 | -0.393 | -0.1181 | No | ||
130 | MECP2 | 5088 | 17092 | -0.484 | -0.1224 | No | ||
131 | DDIT3 | 19857 | 17095 | -0.485 | -0.1148 | No | ||
132 | ATP6V1D | 7872 | 17322 | -0.586 | -0.1176 | No | ||
133 | SMAD5 | 21621 | 17474 | -0.687 | -0.1148 | No | ||
134 | ACTR1A | 23653 | 17500 | -0.703 | -0.1048 | No | ||
135 | TRIM39 | 22994 | 17509 | -0.710 | -0.0939 | No | ||
136 | VDP | 16794 | 17527 | -0.718 | -0.0833 | No | ||
137 | HIBADH | 17144 | 17550 | -0.732 | -0.0727 | No | ||
138 | COG6 | 15345 | 17587 | -0.752 | -0.0626 | No | ||
139 | PDE7A | 9544 1788 | 17634 | -0.780 | -0.0526 | No | ||
140 | BCL7A | 8063 | 17705 | -0.842 | -0.0429 | No | ||
141 | AIP | 23955 | 17779 | -0.893 | -0.0325 | No | ||
142 | COX7A2L | 9819 | 17803 | -0.910 | -0.0192 | No | ||
143 | TCTA | 4167 | 17811 | -0.919 | -0.0048 | No | ||
144 | SRR | 6566 11328 | 17821 | -0.928 | 0.0096 | No | ||
145 | E2F6 | 6925 6926 11920 | 17887 | -0.994 | 0.0220 | No | ||
146 | HNRPH1 | 12222 1486 1220 7202 7201 | 17980 | -1.086 | 0.0344 | No |