Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | V$NFAT_Q6 |
Enrichment Score (ES) | -0.6747429 |
Normalized Enrichment Score (NES) | -1.6348215 |
Nominal p-value | 0.0 |
FDR q-value | 0.031149618 |
FWER p-Value | 0.138 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TNFAIP1 | 20333 | 596 | 1.245 | 0.0000 | No | ||
2 | VAMP8 | 1034 17117 | 1215 | 0.705 | -0.0151 | No | ||
3 | TRPS1 | 8195 | 1392 | 0.594 | -0.0092 | No | ||
4 | MAGED1 | 24108 | 1593 | 0.505 | -0.0070 | No | ||
5 | GTF2E1 | 22597 | 1662 | 0.469 | 0.0015 | No | ||
6 | NDRG2 | 21843 | 1715 | 0.451 | 0.0104 | No | ||
7 | SFRS1 | 8492 | 2269 | 0.270 | -0.0125 | No | ||
8 | HSD3B7 | 4158 | 2422 | 0.231 | -0.0148 | No | ||
9 | CDC2L2 | 15964 2419 | 2459 | 0.222 | -0.0110 | No | ||
10 | RBM14 | 3673 12087 | 2786 | 0.146 | -0.0248 | No | ||
11 | LGALS1 | 22429 | 2850 | 0.135 | -0.0247 | No | ||
12 | MTIF2 | 13354 | 2916 | 0.124 | -0.0250 | No | ||
13 | KIF3C | 9220 4954 | 2938 | 0.121 | -0.0230 | No | ||
14 | HOXC4 | 4864 | 3198 | 0.085 | -0.0349 | No | ||
15 | INPP5E | 14650 | 3483 | 0.064 | -0.0486 | No | ||
16 | PER2 | 3940 13881 | 3489 | 0.063 | -0.0472 | No | ||
17 | ACVR1 | 4334 | 3517 | 0.062 | -0.0471 | No | ||
18 | HSPG2 | 4884 16023 | 3633 | 0.056 | -0.0518 | No | ||
19 | PCDH10 | 5227 9534 1893 | 3793 | 0.048 | -0.0592 | No | ||
20 | FOXP2 | 4312 17523 8523 | 3965 | 0.042 | -0.0674 | No | ||
21 | FJX1 | 4725 | 4043 | 0.039 | -0.0705 | No | ||
22 | ADAMTS17 | 598 | 4079 | 0.038 | -0.0714 | No | ||
23 | FOXP3 | 9804 5426 | 4204 | 0.035 | -0.0772 | No | ||
24 | PAK1IP1 | 21660 | 4323 | 0.032 | -0.0828 | No | ||
25 | TBX4 | 5633 | 4382 | 0.030 | -0.0852 | No | ||
26 | COL25A1 | 8056 1837 1844 1915 13376 | 4385 | 0.030 | -0.0845 | No | ||
27 | ZIC4 | 5992 | 4401 | 0.030 | -0.0845 | No | ||
28 | ANKRD17 | 13496 3474 8170 | 4472 | 0.029 | -0.0876 | No | ||
29 | JDP2 | 21201 | 4706 | 0.025 | -0.0995 | No | ||
30 | IL4 | 9174 | 4896 | 0.022 | -0.1092 | No | ||
31 | HOXB3 | 20685 | 4920 | 0.022 | -0.1099 | No | ||
32 | ELF5 | 14936 2913 | 4938 | 0.022 | -0.1102 | No | ||
33 | SPINK5 | 23569 | 5156 | 0.019 | -0.1215 | No | ||
34 | SOX3 | 24145 | 5386 | 0.017 | -0.1335 | No | ||
35 | LENG4 | 12886 23773 | 5505 | 0.016 | -0.1394 | No | ||
36 | FRS3 | 23209 | 5545 | 0.016 | -0.1411 | No | ||
37 | TRIM47 | 10130 | 5568 | 0.016 | -0.1419 | No | ||
38 | CNTFR | 2515 15906 | 5693 | 0.014 | -0.1483 | No | ||
39 | HOXA2 | 17151 | 5806 | 0.014 | -0.1540 | No | ||
40 | GATA4 | 21792 4755 | 5834 | 0.013 | -0.1551 | No | ||
41 | SGOL1 | 7810 7809 13030 | 5961 | 0.013 | -0.1616 | No | ||
42 | CREB5 | 10551 | 6058 | 0.012 | -0.1665 | No | ||
43 | LIF | 956 667 20960 | 6080 | 0.012 | -0.1673 | No | ||
44 | CFL2 | 2155 21069 | 6115 | 0.012 | -0.1689 | No | ||
45 | NR3C2 | 18562 13798 | 6133 | 0.012 | -0.1695 | No | ||
46 | ZIC1 | 19040 | 6577 | 0.010 | -0.1932 | No | ||
47 | EDN1 | 21658 | 6641 | 0.009 | -0.1964 | No | ||
48 | IGFBP3 | 4898 | 6645 | 0.009 | -0.1963 | No | ||
49 | GNAO1 | 4785 3829 | 6928 | 0.008 | -0.2114 | No | ||
50 | AGTR2 | 24365 | 6965 | 0.008 | -0.2131 | No | ||
51 | SPARCL1 | 16457 | 7057 | 0.008 | -0.2179 | No | ||
52 | IFNB1 | 15846 | 7391 | 0.006 | -0.2357 | No | ||
53 | WISP1 | 22463 2289 | 7567 | 0.006 | -0.2451 | No | ||
54 | SLC26A7 | 5538 2372 | 7640 | 0.006 | -0.2488 | No | ||
55 | TEK | 16175 | 7668 | 0.006 | -0.2501 | No | ||
56 | NR2F2 | 8619 409 | 7868 | 0.005 | -0.2608 | No | ||
57 | SNCAIP | 12589 | 7871 | 0.005 | -0.2608 | No | ||
58 | PHOX2B | 16524 | 7926 | 0.005 | -0.2636 | No | ||
59 | SLC6A12 | 17299 | 8158 | 0.004 | -0.2760 | No | ||
60 | CRY1 | 19662 | 8198 | 0.004 | -0.2780 | No | ||
61 | PDGFB | 22199 2311 | 8208 | 0.004 | -0.2784 | No | ||
62 | RHOA | 8624 4409 4410 | 8262 | 0.004 | -0.2811 | No | ||
63 | ARHGAP5 | 4412 8625 | 8351 | 0.004 | -0.2858 | No | ||
64 | ERG | 1686 8915 | 8404 | 0.004 | -0.2885 | No | ||
65 | UXS1 | 13965 | 8562 | 0.003 | -0.2970 | No | ||
66 | IL2 | 15354 | 8581 | 0.003 | -0.2978 | No | ||
67 | RBMS3 | 18973 | 8660 | 0.003 | -0.3020 | No | ||
68 | SOX21 | 27 10278 2778 | 8887 | 0.002 | -0.3142 | No | ||
69 | BMP5 | 19376 | 8937 | 0.002 | -0.3168 | No | ||
70 | PCDH12 | 7005 | 9487 | 0.001 | -0.3465 | No | ||
71 | CABP2 | 23765 | 9501 | 0.001 | -0.3472 | No | ||
72 | PAK7 | 14417 | 9553 | 0.001 | -0.3499 | No | ||
73 | PLAC1 | 12079 | 9642 | 0.001 | -0.3547 | No | ||
74 | DDR2 | 13767 | 9643 | 0.001 | -0.3547 | No | ||
75 | PTGER1 | 5309 | 9677 | 0.001 | -0.3564 | No | ||
76 | GHR | 22336 | 9880 | 0.000 | -0.3674 | No | ||
77 | TLL1 | 10188 | 9995 | -0.000 | -0.3735 | No | ||
78 | SP3 | 5483 | 10159 | -0.001 | -0.3824 | No | ||
79 | EXOSC9 | 15610 | 10195 | -0.001 | -0.3842 | No | ||
80 | NRK | 6559 | 10342 | -0.001 | -0.3921 | No | ||
81 | FAP | 14577 | 10349 | -0.001 | -0.3924 | No | ||
82 | USP2 | 19480 3052 3043 | 10584 | -0.002 | -0.4051 | No | ||
83 | SOX10 | 22211 | 10591 | -0.002 | -0.4053 | No | ||
84 | TEAD1 | 18121 | 10711 | -0.002 | -0.4117 | No | ||
85 | NFATC4 | 22002 | 10757 | -0.002 | -0.4141 | No | ||
86 | PAX3 | 13910 | 10987 | -0.003 | -0.4265 | No | ||
87 | PITX2 | 15424 1878 | 10992 | -0.003 | -0.4266 | No | ||
88 | CAPN6 | 24041 | 11483 | -0.004 | -0.4531 | No | ||
89 | TIAL1 | 996 5753 | 11789 | -0.005 | -0.4695 | No | ||
90 | SOX5 | 9850 1044 5480 16937 | 11802 | -0.005 | -0.4700 | No | ||
91 | DEPDC2 | 14295 | 11860 | -0.005 | -0.4729 | No | ||
92 | MITF | 17349 | 11903 | -0.005 | -0.4751 | No | ||
93 | MRGPRF | 17995 | 12378 | -0.007 | -0.5006 | No | ||
94 | COL3A1 | 14253 8765 | 12503 | -0.008 | -0.5071 | No | ||
95 | PLOD2 | 19352 | 12645 | -0.008 | -0.5145 | No | ||
96 | SULF1 | 6285 | 12807 | -0.009 | -0.5230 | No | ||
97 | PVRL1 | 3006 19482 12211 7192 | 12853 | -0.009 | -0.5252 | No | ||
98 | DLL4 | 7040 | 12966 | -0.010 | -0.5310 | No | ||
99 | POU4F2 | 9603 5276 | 13020 | -0.010 | -0.5336 | No | ||
100 | FOXB1 | 12254 19069 | 13185 | -0.011 | -0.5422 | No | ||
101 | FLT4 | 20904 1461 | 13351 | -0.012 | -0.5508 | No | ||
102 | COL16A1 | 16066 | 13449 | -0.013 | -0.5557 | No | ||
103 | POU3F3 | 14261 | 13511 | -0.014 | -0.5587 | No | ||
104 | TNXB | 1557 8174 878 8175 | 13627 | -0.015 | -0.5645 | No | ||
105 | ARHGAP6 | 24207 | 13890 | -0.018 | -0.5783 | No | ||
106 | RNF128 | 24236 2641 | 14045 | -0.020 | -0.5861 | No | ||
107 | TRPM3 | 23904 10357 5927 | 14076 | -0.020 | -0.5872 | No | ||
108 | SHOX2 | 1802 5432 | 14158 | -0.022 | -0.5910 | No | ||
109 | COL8A1 | 4548 | 14185 | -0.022 | -0.5918 | No | ||
110 | BNC2 | 15850 | 14331 | -0.025 | -0.5991 | No | ||
111 | JARID2 | 9200 | 14540 | -0.030 | -0.6096 | No | ||
112 | MRPL45 | 20680 | 14708 | -0.035 | -0.6177 | No | ||
113 | HAPLN1 | 21592 | 14711 | -0.035 | -0.6169 | No | ||
114 | ESRRB | 21196 | 14888 | -0.041 | -0.6253 | No | ||
115 | P2RY1 | 15581 | 15042 | -0.048 | -0.6324 | No | ||
116 | TACC2 | 18052 2534 2234 2435 2350 | 15046 | -0.048 | -0.6313 | No | ||
117 | PCBP2 | 9533 | 15180 | -0.055 | -0.6371 | No | ||
118 | LIMS1 | 8493 4290 | 15332 | -0.064 | -0.6436 | No | ||
119 | ELK3 | 4663 94 3388 | 15358 | -0.065 | -0.6433 | No | ||
120 | TNFRSF1A | 1181 10206 | 15409 | -0.069 | -0.6442 | No | ||
121 | COMMD10 | 23561 | 15656 | -0.092 | -0.6551 | No | ||
122 | IRF1 | 1336 1258 1433 9182 | 15764 | -0.106 | -0.6582 | No | ||
123 | MAP4K4 | 11241 | 15790 | -0.111 | -0.6567 | No | ||
124 | TGFB3 | 10161 | 15858 | -0.122 | -0.6571 | No | ||
125 | RAB6A | 18173 3905 | 15866 | -0.123 | -0.6543 | No | ||
126 | PDE4D | 10722 6235 | 15879 | -0.126 | -0.6517 | No | ||
127 | DTX3 | 19607 | 15891 | -0.127 | -0.6490 | No | ||
128 | CPNE1 | 11186 | 16035 | -0.154 | -0.6527 | No | ||
129 | ANP32E | 15500 | 16172 | -0.185 | -0.6553 | No | ||
130 | FBXL20 | 13010 | 16532 | -0.285 | -0.6673 | Yes | ||
131 | PIK3CD | 9563 | 16569 | -0.297 | -0.6616 | Yes | ||
132 | INPP5F | 18055 3877 | 16610 | -0.310 | -0.6557 | Yes | ||
133 | ARF6 | 21252 | 16612 | -0.310 | -0.6477 | Yes | ||
134 | GADD45G | 21637 | 16864 | -0.392 | -0.6512 | Yes | ||
135 | GPX1 | 19310 | 16950 | -0.425 | -0.6447 | Yes | ||
136 | PHF6 | 2648 24340 | 16995 | -0.442 | -0.6356 | Yes | ||
137 | CAPG | 17411 | 17107 | -0.491 | -0.6289 | Yes | ||
138 | MAST2 | 9423 | 17115 | -0.494 | -0.6164 | Yes | ||
139 | SNX2 | 1974 23554 12585 | 17132 | -0.502 | -0.6043 | Yes | ||
140 | TEC | 16514 | 17142 | -0.506 | -0.5916 | Yes | ||
141 | EPHA2 | 16006 | 17190 | -0.522 | -0.5806 | Yes | ||
142 | ADRBK1 | 23960 | 17283 | -0.566 | -0.5709 | Yes | ||
143 | ZHX2 | 11842 | 17361 | -0.610 | -0.5592 | Yes | ||
144 | GSK3B | 22761 | 17375 | -0.618 | -0.5439 | Yes | ||
145 | ZBTB5 | 15891 | 17468 | -0.682 | -0.5312 | Yes | ||
146 | CD84 | 14049 | 17497 | -0.703 | -0.5144 | Yes | ||
147 | HOXB4 | 20686 | 17598 | -0.758 | -0.5002 | Yes | ||
148 | ETV5 | 22630 | 17725 | -0.855 | -0.4848 | Yes | ||
149 | BLR1 | 19145 3154 | 17739 | -0.863 | -0.4631 | Yes | ||
150 | TCTA | 4167 | 17811 | -0.919 | -0.4431 | Yes | ||
151 | TIGD2 | 17429 | 17857 | -0.967 | -0.4204 | Yes | ||
152 | PTOV1 | 13522 | 18030 | -1.145 | -0.4000 | Yes | ||
153 | EMP1 | 17260 | 18069 | -1.200 | -0.3709 | Yes | ||
154 | FOXP1 | 4242 | 18090 | -1.220 | -0.3403 | Yes | ||
155 | ORMDL3 | 12386 | 18098 | -1.228 | -0.3088 | Yes | ||
156 | IRF4 | 21679 | 18103 | -1.237 | -0.2769 | Yes | ||
157 | SSBP3 | 2439 7814 2431 | 18357 | -1.795 | -0.2440 | Yes | ||
158 | TGFB1 | 18332 | 18378 | -1.858 | -0.1968 | Yes | ||
159 | KLF13 | 17807 | 18392 | -1.926 | -0.1475 | Yes | ||
160 | LASP1 | 4986 4985 1248 | 18543 | -2.904 | -0.0802 | Yes | ||
161 | MARCKS | 9331 | 18562 | -3.238 | 0.0029 | Yes |