Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | V$E2F_Q4_01 |
Enrichment Score (ES) | 0.5443237 |
Normalized Enrichment Score (NES) | 1.2947148 |
Nominal p-value | 0.042513862 |
FDR q-value | 0.74363536 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MCM7 | 9372 3568 | 61 | 3.035 | 0.0468 | Yes | ||
2 | UXT | 5837 10267 | 74 | 2.855 | 0.0932 | Yes | ||
3 | IMPDH2 | 10730 | 254 | 1.927 | 0.1153 | Yes | ||
4 | PPRC1 | 23808 | 379 | 1.599 | 0.1350 | Yes | ||
5 | EIF5A | 11345 20379 6590 | 438 | 1.466 | 0.1560 | Yes | ||
6 | UNG | 10257 16744 | 489 | 1.391 | 0.1762 | Yes | ||
7 | NASP | 2383 2387 6955 | 563 | 1.299 | 0.1937 | Yes | ||
8 | CDCA7 | 12437 | 600 | 1.241 | 0.2122 | Yes | ||
9 | RFC1 | 16527 | 604 | 1.237 | 0.2325 | Yes | ||
10 | KPNB1 | 20274 | 617 | 1.219 | 0.2519 | Yes | ||
11 | MCM3 | 13991 | 732 | 1.080 | 0.2636 | Yes | ||
12 | UCHL1 | 16834 | 751 | 1.057 | 0.2800 | Yes | ||
13 | IPO11 | 21353 | 797 | 1.023 | 0.2945 | Yes | ||
14 | DNMT1 | 19217 | 812 | 1.012 | 0.3104 | Yes | ||
15 | YWHAQ | 10369 | 828 | 0.997 | 0.3260 | Yes | ||
16 | NUTF2 | 12632 7529 | 919 | 0.912 | 0.3362 | Yes | ||
17 | ATP5G2 | 12610 | 942 | 0.885 | 0.3496 | Yes | ||
18 | MCM2 | 17074 | 956 | 0.874 | 0.3633 | Yes | ||
19 | TIAM1 | 22547 | 966 | 0.866 | 0.3771 | Yes | ||
20 | CDC25A | 8721 | 990 | 0.847 | 0.3899 | Yes | ||
21 | NCL | 5153 13899 | 1013 | 0.835 | 0.4025 | Yes | ||
22 | SYT11 | 15285 | 1047 | 0.808 | 0.4140 | Yes | ||
23 | PIK3R3 | 5248 | 1062 | 0.797 | 0.4264 | Yes | ||
24 | KNTC1 | 16705 | 1067 | 0.794 | 0.4393 | Yes | ||
25 | POLA2 | 23988 | 1088 | 0.782 | 0.4511 | Yes | ||
26 | ACBD6 | 14089 | 1102 | 0.772 | 0.4631 | Yes | ||
27 | PRIM1 | 19847 | 1166 | 0.734 | 0.4718 | Yes | ||
28 | GMNN | 21513 | 1199 | 0.713 | 0.4818 | Yes | ||
29 | RPS19 | 5398 | 1201 | 0.713 | 0.4935 | Yes | ||
30 | HMGA1 | 23323 | 1282 | 0.655 | 0.5000 | Yes | ||
31 | PCNA | 9535 | 1327 | 0.628 | 0.5080 | Yes | ||
32 | APRIN | 4145 | 1397 | 0.592 | 0.5140 | Yes | ||
33 | PPP1R8 | 15730 | 1474 | 0.553 | 0.5190 | Yes | ||
34 | SUV39H1 | 24194 | 1543 | 0.527 | 0.5240 | Yes | ||
35 | MELK | 2453 16227 | 1654 | 0.474 | 0.5259 | Yes | ||
36 | STMN1 | 9261 | 1739 | 0.442 | 0.5286 | Yes | ||
37 | FANCC | 4712 | 1849 | 0.402 | 0.5293 | Yes | ||
38 | E2F3 | 21500 8874 | 1906 | 0.383 | 0.5326 | Yes | ||
39 | HTF9C | 4886 1678 | 1971 | 0.362 | 0.5351 | Yes | ||
40 | DLST | 8131 | 2002 | 0.351 | 0.5393 | Yes | ||
41 | PIK3R4 | 19333 | 2100 | 0.320 | 0.5393 | Yes | ||
42 | DNAJC11 | 2486 6068 | 2166 | 0.301 | 0.5408 | Yes | ||
43 | RBBP4 | 5364 | 2244 | 0.277 | 0.5412 | Yes | ||
44 | SFRS1 | 8492 | 2269 | 0.270 | 0.5443 | Yes | ||
45 | SFRS2 | 9807 20136 | 2845 | 0.136 | 0.5154 | No | ||
46 | DAXX | 23290 | 3036 | 0.104 | 0.5068 | No | ||
47 | PAQR4 | 23105 | 3055 | 0.102 | 0.5075 | No | ||
48 | ARID4A | 2080 6215 | 3083 | 0.099 | 0.5077 | No | ||
49 | SFMBT1 | 12053 7050 | 3086 | 0.098 | 0.5092 | No | ||
50 | MCM4 | 22655 1708 | 3169 | 0.089 | 0.5062 | No | ||
51 | NCOA6 | 2876 14382 | 3197 | 0.085 | 0.5062 | No | ||
52 | E2F7 | 19884 | 3233 | 0.083 | 0.5057 | No | ||
53 | CASP2 | 8692 | 3238 | 0.082 | 0.5068 | No | ||
54 | WEE1 | 18127 | 3278 | 0.080 | 0.5060 | No | ||
55 | TOP1 | 5790 5789 10210 | 3339 | 0.073 | 0.5039 | No | ||
56 | TNPO2 | 5608 | 3416 | 0.067 | 0.5009 | No | ||
57 | YBX2 | 20818 | 3575 | 0.059 | 0.4933 | No | ||
58 | HOXC10 | 22342 | 3592 | 0.058 | 0.4934 | No | ||
59 | KCND2 | 4941 17515 | 3656 | 0.055 | 0.4909 | No | ||
60 | RAD51 | 2897 14903 | 3745 | 0.050 | 0.4870 | No | ||
61 | SLC38A1 | 22148 | 4001 | 0.040 | 0.4738 | No | ||
62 | ASXL2 | 7957 | 4229 | 0.034 | 0.4621 | No | ||
63 | E2F1 | 14384 | 4578 | 0.027 | 0.4437 | No | ||
64 | HOXA9 | 17147 9109 1024 | 4626 | 0.026 | 0.4416 | No | ||
65 | NEGR1 | 6806 11572 | 4993 | 0.021 | 0.4221 | No | ||
66 | MAP3K13 | 22814 | 5229 | 0.019 | 0.4097 | No | ||
67 | PHF15 | 20467 8050 | 5576 | 0.015 | 0.3912 | No | ||
68 | RANBP1 | 9692 5357 | 5860 | 0.013 | 0.3761 | No | ||
69 | SLBP | 9822 | 5863 | 0.013 | 0.3762 | No | ||
70 | CDC6 | 6221 6220 | 6131 | 0.012 | 0.3619 | No | ||
71 | NR3C2 | 18562 13798 | 6133 | 0.012 | 0.3620 | No | ||
72 | SALL1 | 18796 12207 | 6196 | 0.011 | 0.3589 | No | ||
73 | PODN | 15811 | 6208 | 0.011 | 0.3585 | No | ||
74 | PRKDC | 9617 22847 | 6341 | 0.011 | 0.3515 | No | ||
75 | SEMA5A | 22496 5423 | 6497 | 0.010 | 0.3432 | No | ||
76 | ATAD2 | 2268 2256 | 6590 | 0.010 | 0.3384 | No | ||
77 | SLC6A4 | 20770 | 6753 | 0.009 | 0.3298 | No | ||
78 | EPHB1 | 19024 | 6871 | 0.008 | 0.3236 | No | ||
79 | DPYSL2 | 3122 4561 8787 | 6947 | 0.008 | 0.3197 | No | ||
80 | UFD1L | 22825 | 7362 | 0.007 | 0.2973 | No | ||
81 | GATA3 | 9004 | 7432 | 0.006 | 0.2937 | No | ||
82 | HNRPD | 8645 | 7484 | 0.006 | 0.2910 | No | ||
83 | PCDH7 | 7029 3460 | 7486 | 0.006 | 0.2911 | No | ||
84 | FBXO5 | 19830 | 7527 | 0.006 | 0.2890 | No | ||
85 | STAG1 | 5520 9905 2987 | 7662 | 0.006 | 0.2818 | No | ||
86 | HIST1H1D | 4821 | 7826 | 0.005 | 0.2731 | No | ||
87 | LUC7L2 | 5313 5312 | 8014 | 0.005 | 0.2630 | No | ||
88 | PLK4 | 1870 1874 | 8254 | 0.004 | 0.2502 | No | ||
89 | CITED2 | 5118 14477 | 8286 | 0.004 | 0.2485 | No | ||
90 | ERG | 1686 8915 | 8404 | 0.004 | 0.2423 | No | ||
91 | MAZ | 1327 17623 | 8788 | 0.003 | 0.2216 | No | ||
92 | ADAMTS2 | 5706 20899 1356 | 9006 | 0.002 | 0.2098 | No | ||
93 | GLRA3 | 18617 | 9309 | 0.001 | 0.1935 | No | ||
94 | TOPBP1 | 10659 | 9405 | 0.001 | 0.1884 | No | ||
95 | CDC45L | 22642 1752 | 9951 | -0.000 | 0.1589 | No | ||
96 | EPHB2 | 4675 2440 8910 | 10347 | -0.001 | 0.1375 | No | ||
97 | BAI1 | 22459 | 10352 | -0.001 | 0.1373 | No | ||
98 | CASP8AP2 | 16253 | 10367 | -0.001 | 0.1365 | No | ||
99 | USP2 | 19480 3052 3043 | 10584 | -0.002 | 0.1248 | No | ||
100 | POLE2 | 21053 | 10899 | -0.002 | 0.1079 | No | ||
101 | IPO7 | 6130 | 11087 | -0.003 | 0.0978 | No | ||
102 | EZH2 | 1092 17163 | 11492 | -0.004 | 0.0760 | No | ||
103 | FMO4 | 13786 | 11581 | -0.004 | 0.0713 | No | ||
104 | RNF121 | 7952 373 | 12048 | -0.006 | 0.0461 | No | ||
105 | PEG3 | 5240 | 12236 | -0.007 | 0.0361 | No | ||
106 | TNFRSF19L | 11498 6727 6726 | 12325 | -0.007 | 0.0314 | No | ||
107 | NRP2 | 5194 9486 5195 | 12343 | -0.007 | 0.0306 | No | ||
108 | DCLRE1A | 23641 | 12479 | -0.008 | 0.0234 | No | ||
109 | CBX5 | 22108 4485 | 12504 | -0.008 | 0.0223 | No | ||
110 | PVRL1 | 3006 19482 12211 7192 | 12853 | -0.009 | 0.0036 | No | ||
111 | DIO3 | 19359 | 13052 | -0.010 | -0.0070 | No | ||
112 | TBX3 | 16723 | 13468 | -0.013 | -0.0292 | No | ||
113 | AP1S2 | 8423 4228 | 13483 | -0.013 | -0.0298 | No | ||
114 | RPS6KA5 | 2076 21005 | 13507 | -0.014 | -0.0308 | No | ||
115 | JPH1 | 13994 | 13668 | -0.015 | -0.0392 | No | ||
116 | KCNA6 | 664 16990 665 4938 | 13919 | -0.018 | -0.0525 | No | ||
117 | SLC16A2 | 24086 | 13963 | -0.019 | -0.0545 | No | ||
118 | BMP7 | 14324 | 14052 | -0.020 | -0.0589 | No | ||
119 | H2AFZ | 6957 | 14056 | -0.020 | -0.0588 | No | ||
120 | GPRC5B | 17662 | 14397 | -0.027 | -0.0767 | No | ||
121 | DDB2 | 2721 2878 14525 2661 | 14404 | -0.027 | -0.0766 | No | ||
122 | PCSK4 | 19696 3296 3394 18705 | 14551 | -0.030 | -0.0840 | No | ||
123 | DMD | 24295 2647 | 14603 | -0.032 | -0.0863 | No | ||
124 | AP4M1 | 3499 16656 | 14683 | -0.034 | -0.0900 | No | ||
125 | ERBB2IP | 3232 12234 | 14722 | -0.036 | -0.0915 | No | ||
126 | FANCG | 15904 | 14724 | -0.036 | -0.0909 | No | ||
127 | DMRT1 | 23899 | 15066 | -0.049 | -0.1086 | No | ||
128 | PTMA | 9657 | 15085 | -0.050 | -0.1087 | No | ||
129 | ERF | 4680 8914 | 15246 | -0.059 | -0.1164 | No | ||
130 | MYC | 22465 9435 | 15293 | -0.062 | -0.1179 | No | ||
131 | ZCCHC8 | 3570 7696 | 15327 | -0.064 | -0.1187 | No | ||
132 | KLF5 | 4456 | 15473 | -0.075 | -0.1253 | No | ||
133 | ETV4 | 20212 | 15476 | -0.076 | -0.1241 | No | ||
134 | HMGN2 | 9095 | 15538 | -0.081 | -0.1261 | No | ||
135 | ORC1L | 327 16144 | 15780 | -0.109 | -0.1374 | No | ||
136 | MCM6 | 4000 13845 4119 | 15805 | -0.114 | -0.1368 | No | ||
137 | STAG2 | 5521 | 16062 | -0.160 | -0.1480 | No | ||
138 | ATE1 | 388 17602 | 16134 | -0.175 | -0.1490 | No | ||
139 | BRMS1L | 21268 | 16159 | -0.183 | -0.1473 | No | ||
140 | ANP32E | 15500 | 16172 | -0.185 | -0.1449 | No | ||
141 | ABCF2 | 11338 6580 6579 | 16181 | -0.187 | -0.1422 | No | ||
142 | NDUFA11 | 12832 | 16228 | -0.198 | -0.1414 | No | ||
143 | FBXL20 | 13010 | 16532 | -0.285 | -0.1532 | No | ||
144 | MAP4K1 | 18313 | 16615 | -0.312 | -0.1525 | No | ||
145 | USP52 | 3397 19841 | 16767 | -0.362 | -0.1547 | No | ||
146 | POLE4 | 12441 | 17037 | -0.460 | -0.1616 | No | ||
147 | CTCF | 18490 | 17085 | -0.478 | -0.1563 | No | ||
148 | NHLRC2 | 23828 | 17121 | -0.498 | -0.1500 | No | ||
149 | GPS2 | 12096 | 17275 | -0.564 | -0.1490 | No | ||
150 | MAT2A | 10553 10554 6099 | 17615 | -0.768 | -0.1547 | No | ||
151 | DCK | 16808 | 17693 | -0.826 | -0.1452 | No | ||
152 | AXUD1 | 18967 | 17724 | -0.855 | -0.1327 | No | ||
153 | PPM1D | 20721 | 17849 | -0.958 | -0.1236 | No | ||
154 | RAB11B | 9676 | 17898 | -1.004 | -0.1097 | No | ||
155 | PPP1R9B | 20698 | 18055 | -1.183 | -0.0986 | No | ||
156 | MXD3 | 21455 | 18116 | -1.258 | -0.0811 | No | ||
157 | HNRPA1 | 9103 4860 | 18370 | -1.836 | -0.0646 | No | ||
158 | FBXO9 | 19058 3146 | 18457 | -2.214 | -0.0327 | No | ||
159 | HRBL | 3452 16326 3614 | 18500 | -2.501 | 0.0063 | No |