Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | V$E2F1_Q6_01 |
Enrichment Score (ES) | 0.56634724 |
Normalized Enrichment Score (NES) | 1.3467155 |
Nominal p-value | 0.021543985 |
FDR q-value | 0.7061846 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | FAF1 | 2508 16137 8951 | 19 | 4.195 | 0.0671 | Yes | ||
2 | MCM7 | 9372 3568 | 61 | 3.035 | 0.1141 | Yes | ||
3 | UXT | 5837 10267 | 74 | 2.855 | 0.1599 | Yes | ||
4 | PPRC1 | 23808 | 379 | 1.599 | 0.1693 | Yes | ||
5 | CLSPN | 16079 11256 6530 | 463 | 1.427 | 0.1880 | Yes | ||
6 | MSH2 | 23138 | 480 | 1.403 | 0.2099 | Yes | ||
7 | UNG | 10257 16744 | 489 | 1.391 | 0.2321 | Yes | ||
8 | NASP | 2383 2387 6955 | 563 | 1.299 | 0.2492 | Yes | ||
9 | CDCA7 | 12437 | 600 | 1.241 | 0.2674 | Yes | ||
10 | NOLC1 | 7704 | 649 | 1.175 | 0.2839 | Yes | ||
11 | MCM3 | 13991 | 732 | 1.080 | 0.2970 | Yes | ||
12 | FKBP5 | 23051 | 787 | 1.028 | 0.3108 | Yes | ||
13 | DNMT1 | 19217 | 812 | 1.012 | 0.3259 | Yes | ||
14 | RQCD1 | 12205 | 830 | 0.995 | 0.3411 | Yes | ||
15 | GSPT1 | 9046 | 868 | 0.949 | 0.3545 | Yes | ||
16 | PRPS1 | 24233 | 878 | 0.937 | 0.3693 | Yes | ||
17 | ATP5G2 | 12610 | 942 | 0.885 | 0.3802 | Yes | ||
18 | MCM2 | 17074 | 956 | 0.874 | 0.3937 | Yes | ||
19 | AP1S1 | 3500 3453 16335 | 960 | 0.870 | 0.4077 | Yes | ||
20 | CDC25A | 8721 | 990 | 0.847 | 0.4198 | Yes | ||
21 | NCL | 5153 13899 | 1013 | 0.835 | 0.4322 | Yes | ||
22 | MRPL40 | 22641 | 1084 | 0.785 | 0.4412 | Yes | ||
23 | POLA2 | 23988 | 1088 | 0.782 | 0.4537 | Yes | ||
24 | PHF5A | 22194 | 1098 | 0.775 | 0.4658 | Yes | ||
25 | ACBD6 | 14089 | 1102 | 0.772 | 0.4782 | Yes | ||
26 | GMNN | 21513 | 1199 | 0.713 | 0.4845 | Yes | ||
27 | RPS19 | 5398 | 1201 | 0.713 | 0.4961 | Yes | ||
28 | ACO2 | 8527 | 1318 | 0.634 | 0.5001 | Yes | ||
29 | PCNA | 9535 | 1327 | 0.628 | 0.5098 | Yes | ||
30 | PPP1R8 | 15730 | 1474 | 0.553 | 0.5109 | Yes | ||
31 | HIRA | 4852 9090 | 1541 | 0.528 | 0.5159 | Yes | ||
32 | SUV39H1 | 24194 | 1543 | 0.527 | 0.5244 | Yes | ||
33 | INSM1 | 14815 | 1567 | 0.517 | 0.5316 | Yes | ||
34 | SUMO1 | 5826 3943 10247 | 1684 | 0.465 | 0.5328 | Yes | ||
35 | STMN1 | 9261 | 1739 | 0.442 | 0.5371 | Yes | ||
36 | FANCC | 4712 | 1849 | 0.402 | 0.5377 | Yes | ||
37 | E2F3 | 21500 8874 | 1906 | 0.383 | 0.5409 | Yes | ||
38 | SLC25A1 | 22645 | 1934 | 0.374 | 0.5455 | Yes | ||
39 | EED | 17759 | 1955 | 0.368 | 0.5504 | Yes | ||
40 | HTF9C | 4886 1678 | 1971 | 0.362 | 0.5555 | Yes | ||
41 | ILF3 | 3110 3030 9176 | 2021 | 0.347 | 0.5584 | Yes | ||
42 | POLD3 | 17742 | 2092 | 0.323 | 0.5599 | Yes | ||
43 | DNAJC11 | 2486 6068 | 2166 | 0.301 | 0.5608 | Yes | ||
44 | SFRS1 | 8492 | 2269 | 0.270 | 0.5597 | Yes | ||
45 | USP37 | 13923 | 2297 | 0.264 | 0.5625 | Yes | ||
46 | SIN3A | 5442 | 2340 | 0.255 | 0.5643 | Yes | ||
47 | AMD1 | 8583 | 2377 | 0.244 | 0.5663 | Yes | ||
48 | PHF13 | 15659 | 2545 | 0.202 | 0.5606 | No | ||
49 | CHD4 | 8418 17281 4225 | 2821 | 0.139 | 0.5479 | No | ||
50 | SFRS2 | 9807 20136 | 2845 | 0.136 | 0.5489 | No | ||
51 | PAQR4 | 23105 | 3055 | 0.102 | 0.5392 | No | ||
52 | MCM4 | 22655 1708 | 3169 | 0.089 | 0.5345 | No | ||
53 | NCOA6 | 2876 14382 | 3197 | 0.085 | 0.5345 | No | ||
54 | CASP2 | 8692 | 3238 | 0.082 | 0.5336 | No | ||
55 | WEE1 | 18127 | 3278 | 0.080 | 0.5328 | No | ||
56 | YBX2 | 20818 | 3575 | 0.059 | 0.5177 | No | ||
57 | HOXC10 | 22342 | 3592 | 0.058 | 0.5178 | No | ||
58 | RAD51 | 2897 14903 | 3745 | 0.050 | 0.5104 | No | ||
59 | PCDH10 | 5227 9534 1893 | 3793 | 0.048 | 0.5086 | No | ||
60 | SYNCRIP | 3078 3035 3107 | 3969 | 0.042 | 0.4998 | No | ||
61 | GATA1 | 24196 | 3983 | 0.041 | 0.4998 | No | ||
62 | ASXL2 | 7957 | 4229 | 0.034 | 0.4871 | No | ||
63 | SYNGR4 | 17825 | 4370 | 0.031 | 0.4800 | No | ||
64 | E2F1 | 14384 | 4578 | 0.027 | 0.4692 | No | ||
65 | CNOT3 | 6112 10565 6113 | 4636 | 0.026 | 0.4665 | No | ||
66 | HMGA2 | 4857 9098 3341 3444 | 5408 | 0.017 | 0.4250 | No | ||
67 | PHF15 | 20467 8050 | 5576 | 0.015 | 0.4162 | No | ||
68 | HR | 3622 9119 | 5702 | 0.014 | 0.4097 | No | ||
69 | RANBP1 | 9692 5357 | 5860 | 0.013 | 0.4014 | No | ||
70 | PODN | 15811 | 6208 | 0.011 | 0.3828 | No | ||
71 | HNRPUL1 | 6118 17923 1608 10577 1345 | 6268 | 0.011 | 0.3798 | No | ||
72 | RBL1 | 14373 | 6297 | 0.011 | 0.3784 | No | ||
73 | PRKDC | 9617 22847 | 6341 | 0.011 | 0.3763 | No | ||
74 | TYRO3 | 5811 | 6553 | 0.010 | 0.3650 | No | ||
75 | ATAD2 | 2268 2256 | 6590 | 0.010 | 0.3632 | No | ||
76 | IRX3 | 18793 | 6616 | 0.009 | 0.3620 | No | ||
77 | RB1CC1 | 4486 14299 | 6752 | 0.009 | 0.3548 | No | ||
78 | SYT6 | 13437 7042 12040 | 6826 | 0.009 | 0.3510 | No | ||
79 | ENPP1 | 19804 | 6838 | 0.009 | 0.3506 | No | ||
80 | UFD1L | 22825 | 7362 | 0.007 | 0.3223 | No | ||
81 | PCSK1 | 21600 | 7371 | 0.007 | 0.3220 | No | ||
82 | HNRPD | 8645 | 7484 | 0.006 | 0.3160 | No | ||
83 | FBXO5 | 19830 | 7527 | 0.006 | 0.3139 | No | ||
84 | RPL18 | 450 5390 | 7542 | 0.006 | 0.3132 | No | ||
85 | DHH | 4629 | 7591 | 0.006 | 0.3107 | No | ||
86 | STAG1 | 5520 9905 2987 | 7662 | 0.006 | 0.3070 | No | ||
87 | MYH10 | 8077 | 7791 | 0.005 | 0.3001 | No | ||
88 | TBX6 | 1993 18075 | 8479 | 0.003 | 0.2630 | No | ||
89 | STK35 | 14851 | 8659 | 0.003 | 0.2533 | No | ||
90 | MAZ | 1327 17623 | 8788 | 0.003 | 0.2464 | No | ||
91 | ADAMTS2 | 5706 20899 1356 | 9006 | 0.002 | 0.2347 | No | ||
92 | PAX6 | 5223 | 9241 | 0.002 | 0.2221 | No | ||
93 | TOPBP1 | 10659 | 9405 | 0.001 | 0.2132 | No | ||
94 | ATM | 2976 19115 | 9513 | 0.001 | 0.2075 | No | ||
95 | CDC45L | 22642 1752 | 9951 | -0.000 | 0.1838 | No | ||
96 | NPAT | 19452 6356 | 10031 | -0.000 | 0.1795 | No | ||
97 | HCN3 | 4843 1763 | 10154 | -0.001 | 0.1729 | No | ||
98 | FZD1 | 16923 | 10235 | -0.001 | 0.1686 | No | ||
99 | CASP8AP2 | 16253 | 10367 | -0.001 | 0.1615 | No | ||
100 | USP2 | 19480 3052 3043 | 10584 | -0.002 | 0.1498 | No | ||
101 | POLE2 | 21053 | 10899 | -0.002 | 0.1329 | No | ||
102 | REPS2 | 24018 | 11031 | -0.003 | 0.1258 | No | ||
103 | IPO7 | 6130 | 11087 | -0.003 | 0.1229 | No | ||
104 | MTSS1 | 5585 22285 | 11237 | -0.003 | 0.1149 | No | ||
105 | EZH2 | 1092 17163 | 11492 | -0.004 | 0.1012 | No | ||
106 | LRP1 | 9284 | 11848 | -0.005 | 0.0820 | No | ||
107 | DNAJC9 | 21912 | 12010 | -0.006 | 0.0734 | No | ||
108 | MGAT2 | 21256 | 12264 | -0.007 | 0.0598 | No | ||
109 | TNFRSF19L | 11498 6727 6726 | 12325 | -0.007 | 0.0566 | No | ||
110 | BMP2 | 14833 | 12361 | -0.007 | 0.0549 | No | ||
111 | GNG4 | 21706 | 12498 | -0.008 | 0.0476 | No | ||
112 | CBX5 | 22108 4485 | 12504 | -0.008 | 0.0475 | No | ||
113 | SPHK2 | 1217 1806 12155 | 13294 | -0.012 | 0.0049 | No | ||
114 | TMPO | 5778 | 13362 | -0.013 | 0.0015 | No | ||
115 | KCNS2 | 4949 2232 | 13650 | -0.015 | -0.0138 | No | ||
116 | TNF | 23004 | 13662 | -0.015 | -0.0142 | No | ||
117 | JPH1 | 13994 | 13668 | -0.015 | -0.0142 | No | ||
118 | MCM8 | 14834 | 13704 | -0.016 | -0.0158 | No | ||
119 | ACTN3 | 23967 8540 | 13818 | -0.017 | -0.0217 | No | ||
120 | ARHGAP6 | 24207 | 13890 | -0.018 | -0.0252 | No | ||
121 | EFNA5 | 4655 8884 | 14393 | -0.026 | -0.0520 | No | ||
122 | GPRC5B | 17662 | 14397 | -0.027 | -0.0517 | No | ||
123 | DDB2 | 2721 2878 14525 2661 | 14404 | -0.027 | -0.0516 | No | ||
124 | SMARCA1 | 24165 | 14621 | -0.032 | -0.0628 | No | ||
125 | AP4M1 | 3499 16656 | 14683 | -0.034 | -0.0656 | No | ||
126 | ERBB2IP | 3232 12234 | 14722 | -0.036 | -0.0670 | No | ||
127 | FANCG | 15904 | 14724 | -0.036 | -0.0665 | No | ||
128 | POU2F1 | 5275 3989 4065 4010 | 15053 | -0.048 | -0.0835 | No | ||
129 | PTMA | 9657 | 15085 | -0.050 | -0.0844 | No | ||
130 | ERF | 4680 8914 | 15246 | -0.059 | -0.0921 | No | ||
131 | MYC | 22465 9435 | 15293 | -0.062 | -0.0936 | No | ||
132 | HNRPR | 13196 7909 2500 | 15422 | -0.070 | -0.0994 | No | ||
133 | KLF5 | 4456 | 15473 | -0.075 | -0.1009 | No | ||
134 | NUMA1 | 18167 | 15535 | -0.081 | -0.1029 | No | ||
135 | HMGN2 | 9095 | 15538 | -0.081 | -0.1016 | No | ||
136 | SP1 | 9852 | 15611 | -0.088 | -0.1041 | No | ||
137 | ORC1L | 327 16144 | 15780 | -0.109 | -0.1115 | No | ||
138 | MCM6 | 4000 13845 4119 | 15805 | -0.114 | -0.1109 | No | ||
139 | STAG2 | 5521 | 16062 | -0.160 | -0.1222 | No | ||
140 | ATE1 | 388 17602 | 16134 | -0.175 | -0.1232 | No | ||
141 | BRMS1L | 21268 | 16159 | -0.183 | -0.1215 | No | ||
142 | HIST1H2AH | 11414 | 16314 | -0.219 | -0.1263 | No | ||
143 | PIK3CD | 9563 | 16569 | -0.297 | -0.1352 | No | ||
144 | MAP4K1 | 18313 | 16615 | -0.312 | -0.1326 | No | ||
145 | FHOD1 | 18772 | 16629 | -0.318 | -0.1282 | No | ||
146 | SLC9A7 | 24177 | 16757 | -0.359 | -0.1292 | No | ||
147 | USP52 | 3397 19841 | 16767 | -0.362 | -0.1238 | No | ||
148 | CTCF | 18490 | 17085 | -0.478 | -0.1332 | No | ||
149 | GADD45B | 19935 | 17372 | -0.615 | -0.1387 | No | ||
150 | TRIM39 | 22994 | 17509 | -0.710 | -0.1346 | No | ||
151 | AK2 | 8563 2479 16073 | 17531 | -0.720 | -0.1240 | No | ||
152 | CDC5L | 7746 7745 7744 | 17769 | -0.885 | -0.1225 | No | ||
153 | PPM1D | 20721 | 17849 | -0.958 | -0.1112 | No | ||
154 | RAB11B | 9676 | 17898 | -1.004 | -0.0975 | No | ||
155 | MXD3 | 21455 | 18116 | -1.258 | -0.0888 | No | ||
156 | FLI1 | 4729 | 18275 | -1.571 | -0.0719 | No | ||
157 | CCNT1 | 22140 11607 | 18368 | -1.832 | -0.0471 | No | ||
158 | HNRPA1 | 9103 4860 | 18370 | -1.836 | -0.0174 | No | ||
159 | HIST1H2BK | 11423 | 18384 | -1.888 | 0.0126 | No |