Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | MAPKPATHWAY |
Enrichment Score (ES) | -0.68378973 |
Normalized Enrichment Score (NES) | -1.5269265 |
Nominal p-value | 0.006833713 |
FDR q-value | 0.101232775 |
FWER p-Value | 0.762 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TGFB2 | 5743 | 839 | 0.982 | -0.0127 | No | ||
2 | MAPKAPK3 | 19003 | 1265 | 0.664 | -0.0136 | No | ||
3 | MAPK12 | 2182 2215 22164 | 1533 | 0.532 | -0.0104 | No | ||
4 | MAP3K7 | 16255 | 1728 | 0.446 | -0.0061 | No | ||
5 | MAPK8 | 6459 | 1918 | 0.379 | -0.0037 | No | ||
6 | CHUK | 23665 | 2349 | 0.253 | -0.0185 | No | ||
7 | MAPK6 | 19062 | 2541 | 0.203 | -0.0221 | No | ||
8 | HRAS | 4868 | 2695 | 0.167 | -0.0248 | No | ||
9 | IKBKB | 4907 | 2832 | 0.138 | -0.0276 | No | ||
10 | DAXX | 23290 | 3036 | 0.104 | -0.0351 | No | ||
11 | MAP2K5 | 19088 | 3284 | 0.079 | -0.0458 | No | ||
12 | MKNK2 | 3299 9392 | 3513 | 0.062 | -0.0560 | No | ||
13 | SHC1 | 9813 9812 5430 | 3966 | 0.042 | -0.0790 | No | ||
14 | MAP3K9 | 6872 | 5039 | 0.021 | -0.1362 | No | ||
15 | MAP3K13 | 22814 | 5229 | 0.019 | -0.1458 | No | ||
16 | MAPK13 | 23314 | 6574 | 0.010 | -0.2179 | No | ||
17 | MAPK11 | 2264 9618 22163 | 6874 | 0.008 | -0.2338 | No | ||
18 | MAPK4 | 23409 | 7549 | 0.006 | -0.2700 | No | ||
19 | PAK1 | 9527 | 7592 | 0.006 | -0.2720 | No | ||
20 | MAP3K10 | 3831 17916 | 8050 | 0.004 | -0.2965 | No | ||
21 | CEBPA | 4514 | 8316 | 0.004 | -0.3107 | No | ||
22 | MAP2K7 | 6453 | 8614 | 0.003 | -0.3266 | No | ||
23 | MAP3K6 | 16054 | 8853 | 0.003 | -0.3394 | No | ||
24 | RPS6KA2 | 9759 9758 | 9999 | -0.000 | -0.4012 | No | ||
25 | MAPKAPK5 | 16387 | 10496 | -0.001 | -0.4279 | No | ||
26 | RPS6KA1 | 15725 | 10766 | -0.002 | -0.4423 | No | ||
27 | MAP3K12 | 6454 11164 | 11464 | -0.004 | -0.4798 | No | ||
28 | MAP3K5 | 20079 11166 | 13358 | -0.013 | -0.5815 | No | ||
29 | RPS6KA5 | 2076 21005 | 13507 | -0.014 | -0.5891 | No | ||
30 | MAPK10 | 11169 | 13577 | -0.014 | -0.5923 | No | ||
31 | ATF2 | 4418 2759 | 13658 | -0.015 | -0.5961 | No | ||
32 | MAP3K4 | 23126 | 13828 | -0.017 | -0.6047 | No | ||
33 | CREB1 | 3990 8782 4558 4093 | 14348 | -0.026 | -0.6318 | No | ||
34 | RPS6KB2 | 7198 | 14592 | -0.031 | -0.6439 | No | ||
35 | TGFBR1 | 16213 10165 5745 | 14629 | -0.032 | -0.6448 | No | ||
36 | FOS | 21202 | 14780 | -0.038 | -0.6516 | No | ||
37 | MAP2K2 | 19933 | 14885 | -0.041 | -0.6559 | No | ||
38 | MEF2B | 9377 | 15006 | -0.046 | -0.6608 | No | ||
39 | MAP4K5 | 11853 21048 2101 2142 | 15067 | -0.049 | -0.6624 | No | ||
40 | MAPK7 | 1381 20414 | 15201 | -0.056 | -0.6677 | No | ||
41 | MAP2K1 | 19082 | 15278 | -0.061 | -0.6698 | No | ||
42 | MYC | 22465 9435 | 15293 | -0.062 | -0.6685 | No | ||
43 | MAP3K2 | 11165 | 15499 | -0.077 | -0.6770 | No | ||
44 | SP1 | 9852 | 15611 | -0.088 | -0.6801 | No | ||
45 | RPS6KB1 | 7815 1207 13040 | 15680 | -0.094 | -0.6807 | Yes | ||
46 | MEF2D | 9379 | 15725 | -0.101 | -0.6797 | Yes | ||
47 | MAP4K4 | 11241 | 15790 | -0.111 | -0.6795 | Yes | ||
48 | TGFB3 | 10161 | 15858 | -0.122 | -0.6790 | Yes | ||
49 | PAK2 | 10310 5875 | 15883 | -0.126 | -0.6762 | Yes | ||
50 | MAP3K8 | 23495 | 15958 | -0.139 | -0.6755 | Yes | ||
51 | RIPK1 | 5381 | 15979 | -0.143 | -0.6719 | Yes | ||
52 | MAP4K3 | 22887 | 16032 | -0.154 | -0.6696 | Yes | ||
53 | MEF2C | 3204 9378 | 16157 | -0.182 | -0.6703 | Yes | ||
54 | RPS6KA4 | 23804 | 16167 | -0.184 | -0.6647 | Yes | ||
55 | TRAF2 | 14657 | 16176 | -0.186 | -0.6589 | Yes | ||
56 | MAP4K2 | 6457 | 16334 | -0.224 | -0.6600 | Yes | ||
57 | RPS6KA3 | 8490 | 16343 | -0.228 | -0.6529 | Yes | ||
58 | MAP2K3 | 20856 | 16576 | -0.300 | -0.6555 | Yes | ||
59 | MAX | 21034 | 16577 | -0.301 | -0.6455 | Yes | ||
60 | RAC1 | 16302 | 16592 | -0.304 | -0.6362 | Yes | ||
61 | MAP4K1 | 18313 | 16615 | -0.312 | -0.6270 | Yes | ||
62 | MAP2K4 | 20405 | 16842 | -0.384 | -0.6265 | Yes | ||
63 | MAP2K6 | 20614 1414 | 16879 | -0.397 | -0.6153 | Yes | ||
64 | RAF1 | 17035 | 16923 | -0.414 | -0.6039 | Yes | ||
65 | MKNK1 | 2504 | 16970 | -0.431 | -0.5921 | Yes | ||
66 | MAPK14 | 23313 | 17215 | -0.531 | -0.5876 | Yes | ||
67 | GRB2 | 20149 | 17370 | -0.613 | -0.5756 | Yes | ||
68 | MAPK3 | 6458 11170 | 17396 | -0.634 | -0.5559 | Yes | ||
69 | MEF2A | 1201 5089 3492 | 17426 | -0.654 | -0.5358 | Yes | ||
70 | JUN | 15832 | 17458 | -0.677 | -0.5151 | Yes | ||
71 | NFKB1 | 15160 | 17596 | -0.757 | -0.4973 | Yes | ||
72 | MAP3K14 | 11998 | 17649 | -0.792 | -0.4739 | Yes | ||
73 | RELA | 23783 | 17734 | -0.859 | -0.4499 | Yes | ||
74 | MAP3K11 | 11163 | 17905 | -1.013 | -0.4255 | Yes | ||
75 | MAP3K3 | 20626 | 17998 | -1.103 | -0.3939 | Yes | ||
76 | STAT1 | 3936 5524 | 18114 | -1.257 | -0.3585 | Yes | ||
77 | NFKBIA | 21065 | 18148 | -1.309 | -0.3168 | Yes | ||
78 | MAPKAPK2 | 13838 | 18261 | -1.536 | -0.2720 | Yes | ||
79 | MAP3K1 | 21348 | 18282 | -1.594 | -0.2202 | Yes | ||
80 | MAPK9 | 1233 20903 1383 | 18352 | -1.775 | -0.1651 | Yes | ||
81 | TGFB1 | 18332 | 18378 | -1.858 | -0.1048 | Yes | ||
82 | MAPK1 | 1642 11167 | 18573 | -3.548 | 0.0023 | Yes |