Details for gene set HSA04630_JAK_STAT_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	HSA04630_JAK_STAT_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.6721006
Normalized Enrichment Score (NES)	-1.5960048
Nominal p-value	0.0
FDR q-value	0.0694243
FWER p-Value	0.277

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCND1	4487 4488 8707 17535	170	2.292	0.0519	No
2	PIK3CB	19030	713	1.094	0.0517	No
3	SOCS2	5694	761	1.049	0.0772	No
4	PIK3R3	5248	1062	0.797	0.0822	No
5	IL12RB1	3916 18582	2372	0.245	0.0179	No
6	STAM2	7095 2845	3013	0.108	-0.0139	No
7	SOCS3	20131	3056	0.101	-0.0135	No
8	IL2RB	22219	3134	0.093	-0.0151	No
9	PIK3R2	18850	3916	0.043	-0.0562	No
10	IL6ST	4920	3981	0.041	-0.0586	No
11	IL21R	1398 18084	4052	0.039	-0.0614	No
12	IL6R	1862 4919	4135	0.037	-0.0648	No
13	IFNA1	9147	4178	0.036	-0.0661	No
14	AKT1	8568	4238	0.034	-0.0684	No
15	SPRED2	8539 4332	4259	0.033	-0.0686	No
16	SOCS4	7424	4390	0.030	-0.0748	No
17	CNTF	3741 8761 3680 3736	4547	0.027	-0.0826	No
18	IL15	18826 3801	4617	0.026	-0.0856	No
19	IL4	9174	4896	0.022	-0.1000	No
20	IL5RA	17051	5106	0.020	-0.1108	No
21	IFNE1	15842	5124	0.020	-0.1112	No
22	IL24	976 13841	5132	0.020	-0.1111	No
23	IL15RA	2899 2717 15118 2792	5170	0.019	-0.1126	No
24	IL22RA2	20082	5533	0.016	-0.1317	No
25	IFNA7	9152	5605	0.015	-0.1352	No
26	CNTFR	2515 15906	5693	0.014	-0.1395	No
27	SPRY4	23448	5967	0.013	-0.1539	No
28	IL5	20884 10220	6024	0.012	-0.1566	No
29	LIF	956 667 20960	6080	0.012	-0.1593	No
30	SPRED1	4331	6238	0.011	-0.1675	No
31	TPO	21092	6369	0.010	-0.1742	No
32	AKT2	4365 4366	6731	0.009	-0.1935	No
33	IFNA14	11917	7026	0.008	-0.2092	No
34	IFNA6	17749	7070	0.008	-0.2113	No
35	IL19	13839	7099	0.007	-0.2127	No
36	IL12RB2	17128	7247	0.007	-0.2204	No
37	IL13	20461	7272	0.007	-0.2215	No
38	SOCS7	5308 20679	7279	0.007	-0.2217	No
39	STAT5B	20222	7328	0.007	-0.2241	No
40	IFNB1	15846	7391	0.006	-0.2273	No
41	IFNA2	9149	7468	0.006	-0.2312	No
42	IL9	21444	7564	0.006	-0.2362	No
43	IL10	14145 1510 1553 22902	7655	0.006	-0.2409	No
44	OSMR	22333	7780	0.005	-0.2475	No
45	MPL	15780	8265	0.004	-0.2736	No
46	IFNK	11837	8443	0.003	-0.2831	No
47	PIK3R5	11507	8445	0.003	-0.2830	No
48	IL2	15354	8581	0.003	-0.2903	No
49	IL28RA	10823 16038	9193	0.002	-0.3233	No
50	TSLP	23604 1955	9354	0.001	-0.3319	No
51	PTPN11	5326 16391 9660	9360	0.001	-0.3321	No
52	IL20	13840	9807	0.000	-0.3562	No
53	GHR	22336	9880	0.000	-0.3601	No
54	IL9R	20505	10012	-0.000	-0.3672	No
55	IL22	11948	10124	-0.000	-0.3732	No
56	CBLC	17938	10260	-0.001	-0.3805	No
57	IL23R	17127	10286	-0.001	-0.3818	No
58	IL13RA2	24036	10387	-0.001	-0.3872	No
59	IL12B	20918	10475	-0.001	-0.3919	No
60	IL6	16895	10534	-0.001	-0.3950	No
61	IFNA13	15844	11243	-0.003	-0.4332	No
62	IL22RA1	16037	11338	-0.004	-0.4382	No
63	CTF1	18064	11418	-0.004	-0.4424	No
64	IFNA4	9150	11609	-0.004	-0.4525	No
65	IL13RA1	24361	11611	-0.004	-0.4525	No
66	EPO	8911	11715	-0.005	-0.4579	No
67	SPRY2	21725	11810	-0.005	-0.4629	No
68	CSF3	1394 20671	11910	-0.005	-0.4681	No
69	IL11	17981	12040	-0.006	-0.4749	No
70	PRL	21690	12257	-0.007	-0.4864	No
71	SPRY1	15606 1901	12336	-0.007	-0.4905	No
72	PIK3R1	3170	12501	-0.008	-0.4991	No
73	IL3	20453	12729	-0.009	-0.5112	No
74	CSF2	20454	12730	-0.009	-0.5109	No
75	IL7	4921	12843	-0.009	-0.5167	No
76	IFNAR1	22703	12855	-0.009	-0.5171	No
77	LEP	17505	12934	-0.010	-0.5210	No
78	IL21	12241	12987	-0.010	-0.5236	No
79	SOS1	5476	13043	-0.010	-0.5263	No
80	LIFR	22515 9277	13242	-0.012	-0.5367	No
81	PIK3CA	9562	13536	-0.014	-0.5522	No
82	IL23A	19598	13729	-0.016	-0.5621	No
83	EPOR	19204	13803	-0.017	-0.5656	No
84	LEPR	2531 2349	13946	-0.018	-0.5728	No
85	PIAS2	1948 5102	13991	-0.019	-0.5747	No
86	IFNA5	9151	14067	-0.020	-0.5782	No
87	SOCS5	1619 23141	14515	-0.029	-0.6016	No
88	CBL	19154	14583	-0.031	-0.6044	No
89	IL2RG	24096	14967	-0.044	-0.6240	No
90	STAT4	14251 9907	14999	-0.046	-0.6244	No
91	STAT6	19854 9909	15003	-0.046	-0.6234	No
92	JAK2	23893 9197 3706	15078	-0.050	-0.6260	No
93	STAT5A	20664	15080	-0.050	-0.6248	No
94	IFNAR2	22705 1699	15117	-0.052	-0.6253	No
95	CSF3R	8804 8803 2326 4565	15129	-0.052	-0.6245	No
96	MYC	22465 9435	15293	-0.062	-0.6317	No
97	IL3RA	22091	15380	-0.067	-0.6346	No
98	IFNG	19869	15440	-0.071	-0.6359	No
99	PRLR	9620 5291	15550	-0.082	-0.6396	No
100	CLCF1	12160 3742	15597	-0.086	-0.6398	No
101	CRLF2	16442	15920	-0.130	-0.6537	No
102	JAK3	9198 4936	16236	-0.199	-0.6655	Yes
103	TYK2	12058 19215	16346	-0.228	-0.6653	Yes
104	IFNGR1	20083	16473	-0.268	-0.6650	Yes
105	STAM	2912 15117	16544	-0.289	-0.6610	Yes
106	PIK3CD	9563	16569	-0.297	-0.6544	Yes
107	JAK1	15827	16601	-0.307	-0.6479	Yes
108	AKT3	13739 982	16609	-0.309	-0.6401	Yes
109	PIAS4	19681	16679	-0.334	-0.6349	Yes
110	IL10RB	9169	16849	-0.386	-0.6338	Yes
111	CISH	8743	17015	-0.450	-0.6307	Yes
112	IL4R	18085	17070	-0.471	-0.6211	Yes
113	SOS2	21049	17109	-0.492	-0.6100	Yes
114	CSF2RA	23631	17130	-0.501	-0.5977	Yes
115	IFNGR2	9155 22702	17274	-0.563	-0.5905	Yes
116	PIAS3	15491 672 1906	17286	-0.567	-0.5759	Yes
117	PIM1	23308	17294	-0.572	-0.5611	Yes
118	STAT2	19840	17355	-0.605	-0.5482	Yes
119	GRB2	20149	17370	-0.613	-0.5326	Yes
120	IL2RA	4918	17525	-0.716	-0.5218	Yes
121	SOCS1	4522	17563	-0.738	-0.5042	Yes
122	CCND2	16987	17575	-0.744	-0.4849	Yes
123	PIAS1	7126	17797	-0.905	-0.4728	Yes
124	IL10RA	19137	17983	-1.088	-0.4538	Yes
125	CBLB	5531 22734	18038	-1.159	-0.4258	Yes
126	STAT1	3936 5524	18114	-1.257	-0.3963	Yes
127	CCND3	4489 4490	18115	-1.258	-0.3628	Yes
128	CREBBP	22682 8783	18124	-1.271	-0.3294	Yes
129	BCL2L1	4440 2930 8652	18161	-1.324	-0.2960	Yes
130	STAT3	5525 9906	18327	-1.720	-0.2591	Yes
131	IL12A	4913	18353	-1.783	-0.2129	Yes
132	PTPN6	17002	18512	-2.552	-0.1534	Yes
133	IL7R	9175 4922	18537	-2.794	-0.0802	Yes
134	PIK3CG	6635	18560	-3.168	0.0030	Yes