Details for gene set HSA04620_TOLL_LIKE_RECEPTOR_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	HSA04620_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.6782506
Normalized Enrichment Score (NES)	-1.5418832
Nominal p-value	0.0021929825
FDR q-value	0.08563802
FWER p-Value	0.659

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3CB	19030	713	1.094	-0.0083	No
2	CD86	1660 22601	1048	0.807	-0.0040	No
3	PIK3R3	5248	1062	0.797	0.0173	No
4	TICAM2	23440	1095	0.778	0.0370	No
5	MAPK12	2182 2215 22164	1533	0.532	0.0281	No
6	MAP3K7	16255	1728	0.446	0.0300	No
7	MAPK8	6459	1918	0.379	0.0302	No
8	MYD88	18970	2257	0.274	0.0196	No
9	CHUK	23665	2349	0.253	0.0216	No
10	IRAK1	4916	2512	0.209	0.0187	No
11	TRAF3	21147	2551	0.200	0.0222	No
12	TIRAP	3075 19187	2805	0.143	0.0124	No
13	IKBKB	4907	2832	0.138	0.0149	No
14	TLR4	2329 10191 5770	3280	0.079	-0.0071	No
15	CD14	23452	3379	0.070	-0.0105	No
16	FADD	17536 8950 4711	3699	0.052	-0.0262	No
17	CXCL9	5099	3864	0.045	-0.0338	No
18	PIK3R2	18850	3916	0.043	-0.0354	No
19	IL1B	14431	3930	0.043	-0.0349	No
20	IFNA1	9147	4178	0.036	-0.0473	No
21	AKT1	8568	4238	0.034	-0.0495	No
22	TLR7	24004	5446	0.016	-0.1142	No
23	IFNA7	9152	5605	0.015	-0.1224	No
24	CCL5	20320	6124	0.012	-0.1500	No
25	TLR3	18884	6132	0.012	-0.1500	No
26	MAPK13	23314	6574	0.010	-0.1736	No
27	AKT2	4365 4366	6731	0.009	-0.1818	No
28	MAPK11	2264 9618 22163	6874	0.008	-0.1892	No
29	IFNA14	11917	7026	0.008	-0.1971	No
30	IFNA6	17749	7070	0.008	-0.1993	No
31	IFNB1	15846	7391	0.006	-0.2164	No
32	IFNA2	9149	7468	0.006	-0.2203	No
33	TLR5	14017	8044	0.004	-0.2512	No
34	CCL3	20317	8172	0.004	-0.2579	No
35	MAP3K7IP1	2193 2171 22419	8369	0.004	-0.2684	No
36	PIK3R5	11507	8445	0.003	-0.2724	No
37	MAP2K7	6453	8614	0.003	-0.2814	No
38	LBP	14760	8894	0.002	-0.2964	No
39	NFKB2	23810	9535	0.001	-0.3309	No
40	CXCL10	16477	9536	0.001	-0.3309	No
41	CXCL11	16478	10253	-0.001	-0.3695	No
42	CCL4	1362 20730	10317	-0.001	-0.3729	No
43	TLR8	9308	10380	-0.001	-0.3762	No
44	IL12B	20918	10475	-0.001	-0.3812	No
45	IL6	16895	10534	-0.001	-0.3843	No
46	IFNA13	15844	11243	-0.003	-0.4225	No
47	IKBKE	67	11491	-0.004	-0.4357	No
48	IFNA4	9150	11609	-0.004	-0.4419	No
49	IKBKG	2570 2562 4908	11885	-0.005	-0.4566	No
50	PIK3R1	3170	12501	-0.008	-0.4896	No
51	IFNAR1	22703	12855	-0.009	-0.5084	No
52	TLR9	19331 3127	12923	-0.010	-0.5117	No
53	PIK3CA	9562	13536	-0.014	-0.5444	No
54	MAPK10	11169	13577	-0.014	-0.5461	No
55	TNF	23004	13662	-0.015	-0.5503	No
56	CD80	22758	13913	-0.018	-0.5633	No
57	IFNA5	9151	14067	-0.020	-0.5710	No
58	FOS	21202	14780	-0.038	-0.6084	No
59	MAP2K2	19933	14885	-0.041	-0.6128	No
60	IFNAR2	22705 1699	15117	-0.052	-0.6239	No
61	IRF7	12008	15141	-0.053	-0.6237	No
62	MAP2K1	19082	15278	-0.061	-0.6293	No
63	CD40	10207 2961 2968 5783	15430	-0.071	-0.6355	No
64	MAP3K8	23495	15958	-0.139	-0.6602	No
65	RIPK1	5381	15979	-0.143	-0.6573	No
66	TBK1	12137	16368	-0.236	-0.6717	Yes
67	LY96	14292	16426	-0.252	-0.6679	Yes
68	PIK3CD	9563	16569	-0.297	-0.6673	Yes
69	MAP2K3	20856	16576	-0.300	-0.6594	Yes
70	RAC1	16302	16592	-0.304	-0.6518	Yes
71	AKT3	13739 982	16609	-0.309	-0.6441	Yes
72	IRAK4	22379 11185	16691	-0.337	-0.6392	Yes
73	IRF5	17502	16788	-0.370	-0.6342	Yes
74	CASP8	8694	16802	-0.373	-0.6246	Yes
75	MAP2K4	20405	16842	-0.384	-0.6161	Yes
76	MAP2K6	20614 1414	16879	-0.397	-0.6071	Yes
77	MAPK14	23313	17215	-0.531	-0.6105	Yes
78	TLR1	10190	17377	-0.619	-0.6021	Yes
79	MAPK3	6458 11170	17396	-0.634	-0.5855	Yes
80	JUN	15832	17458	-0.677	-0.5701	Yes
81	IRF3	2149 2188 18255	17548	-0.728	-0.5548	Yes
82	NFKB1	15160	17596	-0.757	-0.5364	Yes
83	TOLLIP	7039 12038	17655	-0.796	-0.5176	Yes
84	RELA	23783	17734	-0.859	-0.4981	Yes
85	MAP3K7IP2	19827	17902	-1.009	-0.4792	Yes
86	TRAF6	5797 14940	17908	-1.020	-0.4513	Yes
87	STAT1	3936 5524	18114	-1.257	-0.4276	Yes
88	SPP1	5501	18120	-1.261	-0.3931	Yes
89	NFKBIA	21065	18148	-1.309	-0.3584	Yes
90	TLR2	15308	18150	-1.311	-0.3222	Yes
91	MAPK9	1233 20903 1383	18352	-1.775	-0.2841	Yes
92	IL12A	4913	18353	-1.783	-0.2348	Yes
93	TLR6	215 16528	18467	-2.294	-0.1776	Yes
94	PIK3CG	6635	18560	-3.168	-0.0950	Yes
95	MAPK1	1642 11167	18573	-3.548	0.0023	Yes