Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | HSA04060_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION |
Enrichment Score (ES) | -0.67213887 |
Normalized Enrichment Score (NES) | -1.6905409 |
Nominal p-value | 0.0 |
FDR q-value | 0.04585998 |
FWER p-Value | 0.037 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | VEGFB | 23800 | 769 | 1.040 | -0.0107 | No | ||
2 | TGFB2 | 5743 | 839 | 0.982 | 0.0149 | No | ||
3 | ACVR2B | 19276 | 1040 | 0.813 | 0.0283 | No | ||
4 | CSF1 | 15202 | 2131 | 0.309 | -0.0217 | No | ||
5 | IL12RB1 | 3916 18582 | 2372 | 0.245 | -0.0274 | No | ||
6 | CCL27 | 5419 | 3110 | 0.096 | -0.0646 | No | ||
7 | IL2RB | 22219 | 3134 | 0.093 | -0.0631 | No | ||
8 | IL18R1 | 14263 | 3182 | 0.087 | -0.0630 | No | ||
9 | VEGFA | 22969 | 3350 | 0.072 | -0.0699 | No | ||
10 | ACVR1 | 4334 | 3517 | 0.062 | -0.0771 | No | ||
11 | IL1R1 | 14264 3987 | 3579 | 0.059 | -0.0787 | No | ||
12 | TNFSF18 | 10789 6290 | 3771 | 0.049 | -0.0876 | No | ||
13 | CCL22 | 18518 | 3774 | 0.049 | -0.0862 | No | ||
14 | CXCL9 | 5099 | 3864 | 0.045 | -0.0897 | No | ||
15 | TNFRSF17 | 22856 | 3918 | 0.043 | -0.0913 | No | ||
16 | IL1B | 14431 | 3930 | 0.043 | -0.0906 | No | ||
17 | IL6ST | 4920 | 3981 | 0.041 | -0.0921 | No | ||
18 | IL21R | 1398 18084 | 4052 | 0.039 | -0.0948 | No | ||
19 | CXCL12 | 9792 1182 1031 | 4059 | 0.039 | -0.0939 | No | ||
20 | IL6R | 1862 4919 | 4135 | 0.037 | -0.0969 | No | ||
21 | IFNA1 | 9147 | 4178 | 0.036 | -0.0981 | No | ||
22 | AMHR2 | 8487 22345 | 4207 | 0.035 | -0.0986 | No | ||
23 | TNFRSF10B | 21971 10205 5781 10204 | 4231 | 0.034 | -0.0988 | No | ||
24 | CNTF | 3741 8761 3680 3736 | 4547 | 0.027 | -0.1151 | No | ||
25 | IL15 | 18826 3801 | 4617 | 0.026 | -0.1181 | No | ||
26 | XCR1 | 18953 | 4651 | 0.026 | -0.1191 | No | ||
27 | PPBP | 16801 | 4662 | 0.025 | -0.1189 | No | ||
28 | TNFRSF21 | 8244 | 4672 | 0.025 | -0.1186 | No | ||
29 | TNFSF13 | 12806 | 4674 | 0.025 | -0.1180 | No | ||
30 | LTBR | 16993 | 4892 | 0.022 | -0.1291 | No | ||
31 | IL4 | 9174 | 4896 | 0.022 | -0.1286 | No | ||
32 | IL5RA | 17051 | 5106 | 0.020 | -0.1393 | No | ||
33 | IFNE1 | 15842 | 5124 | 0.020 | -0.1397 | No | ||
34 | IL24 | 976 13841 | 5132 | 0.020 | -0.1395 | No | ||
35 | IL1A | 4915 | 5169 | 0.019 | -0.1409 | No | ||
36 | IL15RA | 2899 2717 15118 2792 | 5170 | 0.019 | -0.1403 | No | ||
37 | TNFRSF8 | 2373 5784 | 5248 | 0.018 | -0.1439 | No | ||
38 | FLT3 | 16288 | 5400 | 0.017 | -0.1516 | No | ||
39 | TNFSF13B | 6291 10792 | 5409 | 0.017 | -0.1515 | No | ||
40 | TNFSF10 | 15626 | 5425 | 0.017 | -0.1519 | No | ||
41 | TGFBR2 | 2994 3001 10167 | 5531 | 0.016 | -0.1571 | No | ||
42 | IL22RA2 | 20082 | 5533 | 0.016 | -0.1567 | No | ||
43 | PDGFC | 7048 | 5589 | 0.015 | -0.1592 | No | ||
44 | IFNA7 | 9152 | 5605 | 0.015 | -0.1596 | No | ||
45 | CNTFR | 2515 15906 | 5693 | 0.014 | -0.1639 | No | ||
46 | CCL24 | 16342 | 5737 | 0.014 | -0.1658 | No | ||
47 | CCL17 | 18517 | 5764 | 0.014 | -0.1668 | No | ||
48 | CSF1R | 8800 23540 | 5835 | 0.013 | -0.1702 | No | ||
49 | IL8RA | 13925 | 5870 | 0.013 | -0.1716 | No | ||
50 | CCR2 | 19250 | 5888 | 0.013 | -0.1722 | No | ||
51 | IL5 | 20884 10220 | 6024 | 0.012 | -0.1791 | No | ||
52 | LIF | 956 667 20960 | 6080 | 0.012 | -0.1818 | No | ||
53 | CCL5 | 20320 | 6124 | 0.012 | -0.1838 | No | ||
54 | KIT | 16823 | 6215 | 0.011 | -0.1883 | No | ||
55 | TPO | 21092 | 6369 | 0.010 | -0.1963 | No | ||
56 | CCR8 | 19272 | 6476 | 0.010 | -0.2018 | No | ||
57 | CCL1 | 9787 | 6582 | 0.010 | -0.2072 | No | ||
58 | CCL8 | 20740 | 6837 | 0.009 | -0.2208 | No | ||
59 | IL1R2 | 14265 | 6984 | 0.008 | -0.2285 | No | ||
60 | IFNA14 | 11917 | 7026 | 0.008 | -0.2305 | No | ||
61 | IFNA6 | 17749 | 7070 | 0.008 | -0.2326 | No | ||
62 | IL19 | 13839 | 7099 | 0.007 | -0.2339 | No | ||
63 | IL12RB2 | 17128 | 7247 | 0.007 | -0.2416 | No | ||
64 | EDAR | 19764 | 7251 | 0.007 | -0.2416 | No | ||
65 | IL13 | 20461 | 7272 | 0.007 | -0.2425 | No | ||
66 | XCL1 | 13781 | 7336 | 0.007 | -0.2457 | No | ||
67 | IFNB1 | 15846 | 7391 | 0.006 | -0.2484 | No | ||
68 | CCR9 | 8753 | 7393 | 0.006 | -0.2483 | No | ||
69 | MET | 17520 | 7437 | 0.006 | -0.2505 | No | ||
70 | IFNA2 | 9149 | 7468 | 0.006 | -0.2519 | No | ||
71 | CXCL16 | 7251 | 7497 | 0.006 | -0.2532 | No | ||
72 | IL9 | 21444 | 7564 | 0.006 | -0.2566 | No | ||
73 | IL10 | 14145 1510 1553 22902 | 7655 | 0.006 | -0.2614 | No | ||
74 | IL8RB | 8752 4533 | 7746 | 0.005 | -0.2661 | No | ||
75 | OSMR | 22333 | 7780 | 0.005 | -0.2677 | No | ||
76 | TNFRSF9 | 10208 5785 | 7948 | 0.005 | -0.2767 | No | ||
77 | GDF5 | 4768 | 8007 | 0.005 | -0.2797 | No | ||
78 | KDR | 16509 | 8028 | 0.005 | -0.2806 | No | ||
79 | CCL7 | 20743 | 8114 | 0.004 | -0.2851 | No | ||
80 | CCL3 | 20317 | 8172 | 0.004 | -0.2881 | No | ||
81 | PDGFRA | 16824 | 8179 | 0.004 | -0.2883 | No | ||
82 | PDGFB | 22199 2311 | 8208 | 0.004 | -0.2897 | No | ||
83 | MPL | 15780 | 8265 | 0.004 | -0.2926 | No | ||
84 | IL17A | 14289 | 8270 | 0.004 | -0.2927 | No | ||
85 | CD40LG | 24330 | 8298 | 0.004 | -0.2941 | No | ||
86 | IL25 | 22014 | 8441 | 0.003 | -0.3017 | No | ||
87 | IFNK | 11837 | 8443 | 0.003 | -0.3017 | No | ||
88 | ACVR2A | 8542 | 8475 | 0.003 | -0.3032 | No | ||
89 | IL2 | 15354 | 8581 | 0.003 | -0.3088 | No | ||
90 | CCR1 | 18951 | 8645 | 0.003 | -0.3122 | No | ||
91 | CX3CL1 | 9791 | 8685 | 0.003 | -0.3142 | No | ||
92 | IL28RA | 10823 16038 | 9193 | 0.002 | -0.3417 | No | ||
93 | INHBC | 19603 | 9351 | 0.001 | -0.3502 | No | ||
94 | TSLP | 23604 1955 | 9354 | 0.001 | -0.3503 | No | ||
95 | TNFSF12 | 10209 | 9371 | 0.001 | -0.3511 | No | ||
96 | CXCL14 | 21445 7165 | 9382 | 0.001 | -0.3516 | No | ||
97 | CXCL10 | 16477 | 9536 | 0.001 | -0.3599 | No | ||
98 | TNFRSF25 | 2334 15983 | 9571 | 0.001 | -0.3617 | No | ||
99 | EDA2R | 6364 | 9593 | 0.001 | -0.3629 | No | ||
100 | TNFSF9 | 23175 | 9691 | 0.001 | -0.3681 | No | ||
101 | CCL11 | 20742 | 9713 | 0.000 | -0.3692 | No | ||
102 | IL20 | 13840 | 9807 | 0.000 | -0.3743 | No | ||
103 | GHR | 22336 | 9880 | 0.000 | -0.3782 | No | ||
104 | TNFRSF11B | 22296 | 9893 | 0.000 | -0.3788 | No | ||
105 | FLT1 | 3483 16287 | 9989 | -0.000 | -0.3840 | No | ||
106 | IL9R | 20505 | 10012 | -0.000 | -0.3852 | No | ||
107 | IL22 | 11948 | 10124 | -0.000 | -0.3912 | No | ||
108 | CXCL11 | 16478 | 10253 | -0.001 | -0.3981 | No | ||
109 | IL23R | 17127 | 10286 | -0.001 | -0.3999 | No | ||
110 | TNFSF15 | 15863 | 10316 | -0.001 | -0.4014 | No | ||
111 | CCL4 | 1362 20730 | 10317 | -0.001 | -0.4014 | No | ||
112 | IL12B | 20918 | 10475 | -0.001 | -0.4099 | No | ||
113 | CCR5 | 8754 4534 | 10515 | -0.001 | -0.4120 | No | ||
114 | IL6 | 16895 | 10534 | -0.001 | -0.4129 | No | ||
115 | HGF | 16916 | 10648 | -0.002 | -0.4190 | No | ||
116 | TNFRSF11A | 14167 | 10773 | -0.002 | -0.4257 | No | ||
117 | TNFSF8 | 15862 | 11049 | -0.003 | -0.4405 | No | ||
118 | CCL2 | 9788 | 11156 | -0.003 | -0.4462 | No | ||
119 | CXCL5 | 16802 | 11222 | -0.003 | -0.4496 | No | ||
120 | IFNA13 | 15844 | 11243 | -0.003 | -0.4506 | No | ||
121 | IL22RA1 | 16037 | 11338 | -0.004 | -0.4556 | No | ||
122 | CXCR3 | 24093 | 11361 | -0.004 | -0.4567 | No | ||
123 | CTF1 | 18064 | 11418 | -0.004 | -0.4596 | No | ||
124 | CXCL2 | 9790 | 11462 | -0.004 | -0.4619 | No | ||
125 | IFNA4 | 9150 | 11609 | -0.004 | -0.4697 | No | ||
126 | IL13RA1 | 24361 | 11611 | -0.004 | -0.4696 | No | ||
127 | EPO | 8911 | 11715 | -0.005 | -0.4750 | No | ||
128 | CSF3 | 1394 20671 | 11910 | -0.005 | -0.4854 | No | ||
129 | IL11 | 17981 | 12040 | -0.006 | -0.4923 | No | ||
130 | EGF | 15169 | 12130 | -0.006 | -0.4969 | No | ||
131 | CCR3 | 19251 | 12158 | -0.006 | -0.4982 | No | ||
132 | INHBB | 13858 | 12235 | -0.007 | -0.5021 | No | ||
133 | PRL | 21690 | 12257 | -0.007 | -0.5031 | No | ||
134 | IL18RAP | 14262 | 12314 | -0.007 | -0.5059 | No | ||
135 | CCL19 | 10773 | 12316 | -0.007 | -0.5058 | No | ||
136 | BMP2 | 14833 | 12361 | -0.007 | -0.5080 | No | ||
137 | IL17B | 12074 | 12532 | -0.008 | -0.5170 | No | ||
138 | IL3 | 20453 | 12729 | -0.009 | -0.5273 | No | ||
139 | CSF2 | 20454 | 12730 | -0.009 | -0.5271 | No | ||
140 | IL7 | 4921 | 12843 | -0.009 | -0.5329 | No | ||
141 | IFNAR1 | 22703 | 12855 | -0.009 | -0.5332 | No | ||
142 | NGFR | 5174 | 12926 | -0.010 | -0.5367 | No | ||
143 | LEP | 17505 | 12934 | -0.010 | -0.5368 | No | ||
144 | IL17RB | 21898 | 12978 | -0.010 | -0.5389 | No | ||
145 | CD70 | 22916 | 12980 | -0.010 | -0.5386 | No | ||
146 | IL21 | 12241 | 12987 | -0.010 | -0.5386 | No | ||
147 | CXCR6 | 19252 | 12990 | -0.010 | -0.5384 | No | ||
148 | CX3CR1 | 18965 | 13062 | -0.010 | -0.5420 | No | ||
149 | LTA | 23003 | 13218 | -0.012 | -0.5501 | No | ||
150 | LIFR | 22515 9277 | 13242 | -0.012 | -0.5510 | No | ||
151 | FLT4 | 20904 1461 | 13351 | -0.012 | -0.5565 | No | ||
152 | PDGFRB | 23539 | 13448 | -0.013 | -0.5613 | No | ||
153 | CXCL13 | 16789 | 13482 | -0.013 | -0.5627 | No | ||
154 | BMPR1B | 8661 15152 4451 | 13546 | -0.014 | -0.5657 | No | ||
155 | TNF | 23004 | 13662 | -0.015 | -0.5715 | No | ||
156 | IL23A | 19598 | 13729 | -0.016 | -0.5746 | No | ||
157 | EPOR | 19204 | 13803 | -0.017 | -0.5781 | No | ||
158 | CCL25 | 9789 3848 | 13843 | -0.017 | -0.5797 | No | ||
159 | CCL28 | 7156 | 13846 | -0.017 | -0.5793 | No | ||
160 | KITLG | 19889 3342 | 13909 | -0.018 | -0.5821 | No | ||
161 | LEPR | 2531 2349 | 13946 | -0.018 | -0.5835 | No | ||
162 | TNFRSF4 | 15954 | 14006 | -0.019 | -0.5861 | No | ||
163 | INHBE | 19604 | 14048 | -0.020 | -0.5878 | No | ||
164 | BMP7 | 14324 | 14052 | -0.020 | -0.5873 | No | ||
165 | BMPR2 | 14241 4081 | 14065 | -0.020 | -0.5874 | No | ||
166 | IFNA5 | 9151 | 14067 | -0.020 | -0.5868 | No | ||
167 | TNFRSF1B | 5782 2346 | 14109 | -0.021 | -0.5884 | No | ||
168 | IL1RAP | 1653 1676 4917 1748 1712 9173 | 14177 | -0.022 | -0.5914 | No | ||
169 | BMPR1A | 8660 4450 | 14236 | -0.023 | -0.5939 | No | ||
170 | CD27 | 16994 | 14292 | -0.024 | -0.5961 | No | ||
171 | CXCL1 | 9044 | 14336 | -0.025 | -0.5977 | No | ||
172 | FASLG | 13789 | 14495 | -0.029 | -0.6055 | No | ||
173 | AMH | 19939 | 14523 | -0.029 | -0.6060 | No | ||
174 | EDA | 24284 | 14567 | -0.031 | -0.6075 | No | ||
175 | TNFSF11 | 21745 | 14574 | -0.031 | -0.6069 | No | ||
176 | TNFSF4 | 14082 | 14596 | -0.031 | -0.6071 | No | ||
177 | TGFBR1 | 16213 10165 5745 | 14629 | -0.032 | -0.6079 | No | ||
178 | TNFSF14 | 1584 22914 | 14647 | -0.033 | -0.6078 | No | ||
179 | ACVR1B | 4335 22353 | 14681 | -0.034 | -0.6086 | No | ||
180 | CCR4 | 18978 | 14828 | -0.039 | -0.6153 | No | ||
181 | IL2RG | 24096 | 14967 | -0.044 | -0.6215 | No | ||
182 | EGFR | 1329 20944 | 14989 | -0.045 | -0.6213 | No | ||
183 | IFNAR2 | 22705 1699 | 15117 | -0.052 | -0.6266 | No | ||
184 | CSF3R | 8804 8803 2326 4565 | 15129 | -0.052 | -0.6257 | No | ||
185 | IL3RA | 22091 | 15380 | -0.067 | -0.6372 | No | ||
186 | CCR6 | 1505 23390 | 15385 | -0.068 | -0.6354 | No | ||
187 | TNFRSF1A | 1181 10206 | 15409 | -0.069 | -0.6346 | No | ||
188 | CD40 | 10207 2961 2968 5783 | 15430 | -0.071 | -0.6336 | No | ||
189 | IFNG | 19869 | 15440 | -0.071 | -0.6320 | No | ||
190 | PRLR | 9620 5291 | 15550 | -0.082 | -0.6354 | No | ||
191 | CLCF1 | 12160 3742 | 15597 | -0.086 | -0.6354 | No | ||
192 | FAS | 23881 3750 | 15668 | -0.094 | -0.6364 | No | ||
193 | VEGFC | 10286 | 15758 | -0.105 | -0.6381 | No | ||
194 | PF4 | 16800 | 15771 | -0.107 | -0.6355 | No | ||
195 | TGFB3 | 10161 | 15858 | -0.122 | -0.6366 | No | ||
196 | CRLF2 | 16442 | 15920 | -0.130 | -0.6360 | No | ||
197 | TNFRSF12A | 23107 | 16255 | -0.206 | -0.6480 | No | ||
198 | IFNGR1 | 20083 | 16473 | -0.268 | -0.6518 | No | ||
199 | IL10RB | 9169 | 16849 | -0.386 | -0.6606 | Yes | ||
200 | IL17RA | 4914 | 16898 | -0.406 | -0.6511 | Yes | ||
201 | IL4R | 18085 | 17070 | -0.471 | -0.6463 | Yes | ||
202 | CCR7 | 20254 | 17126 | -0.500 | -0.6343 | Yes | ||
203 | CSF2RA | 23631 | 17130 | -0.501 | -0.6195 | Yes | ||
204 | TNFRSF14 | 15650 | 17199 | -0.524 | -0.6076 | Yes | ||
205 | IFNGR2 | 9155 22702 | 17274 | -0.563 | -0.5948 | Yes | ||
206 | TNFRSF18 | 15955 2394 | 17327 | -0.589 | -0.5800 | Yes | ||
207 | IL2RA | 4918 | 17525 | -0.716 | -0.5693 | Yes | ||
208 | IL10RA | 19137 | 17983 | -1.088 | -0.5616 | Yes | ||
209 | IL18 | 9172 | 18031 | -1.145 | -0.5300 | Yes | ||
210 | TNFRSF13B | 7181 | 18289 | -1.615 | -0.4957 | Yes | ||
211 | IL12A | 4913 | 18353 | -1.783 | -0.4458 | Yes | ||
212 | TGFB1 | 18332 | 18378 | -1.858 | -0.3916 | Yes | ||
213 | CXCR4 | 13844 | 18494 | -2.475 | -0.3239 | Yes | ||
214 | LTB | 23259 | 18509 | -2.544 | -0.2486 | Yes | ||
215 | IL7R | 9175 4922 | 18537 | -2.794 | -0.1666 | Yes | ||
216 | TNFRSF19 | 21799 3033 | 18538 | -2.835 | -0.0819 | Yes | ||
217 | TNFRSF13C | 22191 | 18541 | -2.879 | 0.0041 | Yes |