Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	DMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	0.7513286
Normalized Enrichment Score (NES)	1.749603
Nominal p-value	0.0
FDR q-value	7.8125007E-4
FWER p-Value	0.0010

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR1D	3593 3658 16623	4	5.920	0.0738	Yes
2	POLR1B	14857	36	3.607	0.1171	Yes
3	APRT	8620	95	2.643	0.1470	Yes
4	GART	22543 1754	107	2.575	0.1786	Yes
5	ATIC	14231 3968	108	2.568	0.2107	Yes
6	NME4	23065 1577	120	2.545	0.2419	Yes
7	NP	22027 9597 5273 5274	123	2.541	0.2736	Yes
8	NME2	9468	150	2.439	0.3026	Yes
9	POLD2	20537	230	2.045	0.3239	Yes
10	ADA	2703 14361	236	2.017	0.3488	Yes
11	IMPDH2	10730	254	1.927	0.3720	Yes
12	NME1	9467	273	1.870	0.3944	Yes
13	PPAT	6081	274	1.868	0.4177	Yes
14	RRM2	5401 5400	303	1.762	0.4382	Yes
15	NUDT5	15121	324	1.702	0.4584	Yes
16	GUK1	20432	335	1.679	0.4788	Yes
17	POLR2H	10888	365	1.631	0.4976	Yes
18	ADSL	4358	398	1.551	0.5153	Yes
19	PDE6D	13897 3945	402	1.538	0.5343	Yes
20	POLR2K	9413	407	1.525	0.5532	Yes
21	POLE	16755	455	1.444	0.5687	Yes
22	POLR3H	13460 8135	471	1.412	0.5855	Yes
23	RFC5	13005 7791	491	1.389	0.6018	Yes
24	NME6	3139 19297	523	1.347	0.6170	Yes
25	PAICS	16820	542	1.323	0.6325	Yes
26	POLR2E	3325 19699	551	1.316	0.6485	Yes
27	POLE3	7200	650	1.174	0.6579	Yes
28	NT5M	8345 4175	671	1.154	0.6712	Yes
29	RRM1	18163	718	1.089	0.6824	Yes
30	ENTPD4	7449	742	1.070	0.6945	Yes
31	GMPS	15578	748	1.059	0.7074	Yes
32	PRPS1	24233	878	0.937	0.7122	Yes
33	NUDT9	7897	887	0.932	0.7234	Yes
34	POLR2J	16672	1011	0.836	0.7272	Yes
35	POLA2	23988	1088	0.782	0.7328	Yes
36	PRIM1	19847	1166	0.734	0.7379	Yes
37	NUDT2	16239	1179	0.724	0.7463	Yes
38	IMPDH1	17197 1131	1244	0.683	0.7513	Yes
39	PRPS2	24003	1678	0.466	0.7337	No
40	POLR3A	21900	1748	0.438	0.7355	No
41	PDE8A	18202	1808	0.416	0.7375	No
42	POLR2I	12839	1841	0.404	0.7408	No
43	POLD3	17742	2092	0.323	0.7313	No
44	POLR3B	12875	2603	0.192	0.7061	No
45	POLR2G	23753	2623	0.184	0.7074	No
46	PNPT1	20936	2683	0.171	0.7063	No
47	NT5C3	17136	2720	0.162	0.7064	No
48	POLR2A	5394	2733	0.159	0.7077	No
49	ECGF1	22160	2875	0.132	0.7018	No
50	PDE10A	23387	3378	0.070	0.6755	No
51	AK3L1	8564	3435	0.066	0.6733	No
52	NT5E	19360 18702	3615	0.057	0.6643	No
53	ADCY3	21329 894	3986	0.041	0.6448	No
54	AK5	6042	4325	0.032	0.6269	No
55	ENTPD6	4496 2678	4455	0.029	0.6203	No
56	POLR1A	9749 5393	4624	0.026	0.6115	No
57	PDE5A	15431	5225	0.019	0.5793	No
58	PDE6G	20119	5342	0.017	0.5733	No
59	GUCY1A3	7216 12245 15310	5510	0.016	0.5644	No
60	NME7	926 4101 14070 3986 3946 931	5926	0.013	0.5421	No
61	AMPD2	1931 15197	6243	0.011	0.5252	No
62	RRM2B	6902 6903 11801	6266	0.011	0.5241	No
63	ENTPD1	4495	6431	0.010	0.5154	No
64	ENTPD3	19266	6632	0.009	0.5047	No
65	ADCY4	2980 21818	6723	0.009	0.4999	No
66	ENTPD8	12996	6756	0.009	0.4983	No
67	ENPP1	19804	6838	0.009	0.4940	No
68	PDE8B	5756	7065	0.008	0.4819	No
69	PDE1A	9541 5234	7446	0.006	0.4614	No
70	GUCY1A2	19580	7790	0.005	0.4429	No
71	XDH	22897	7805	0.005	0.4422	No
72	ALLC	21093 2130	8130	0.004	0.4248	No
73	POLR3K	12447 7372	8352	0.004	0.4129	No
74	GUCY2F	24045	8436	0.003	0.4084	No
75	AK1	4363	8517	0.003	0.4041	No
76	NPR1	9480	9201	0.002	0.3672	No
77	ADK	3302 3454 8555	9399	0.001	0.3566	No
78	GUCY1B3	15311	9545	0.001	0.3487	No
79	GDA	4764	9794	0.000	0.3353	No
80	POLA1	24112	9841	0.000	0.3328	No
81	PDE9A	23301	10122	-0.000	0.3177	No
82	ITPA	9193	10238	-0.001	0.3115	No
83	GUCY2C	1140 16954	10819	-0.002	0.2802	No
84	POLE2	21053	10899	-0.002	0.2759	No
85	PAPSS2	6258	11225	-0.003	0.2584	No
86	ENPP3	19803	11279	-0.003	0.2555	No
87	ADCY2	21412	11355	-0.004	0.2515	No
88	ADCY5	10312	11745	-0.005	0.2306	No
89	AMPD3	4383 2110	11808	-0.005	0.2273	No
90	POLR2B	16817	11867	-0.005	0.2242	No
91	ADCY8	22281	12049	-0.006	0.2145	No
92	PDE4A	3037 19542 3083 3023	12615	-0.008	0.1840	No
93	PKLR	1850 15545	12649	-0.008	0.1823	No
94	PDE1C	5235	12778	-0.009	0.1755	No
95	AMPD1	5051	12802	-0.009	0.1744	No
96	POLR2C	9750	12996	-0.010	0.1641	No
97	ENTPD2	8713	13162	-0.011	0.1553	No
98	PDE11A	10805	13175	-0.011	0.1548	No
99	ADCY6	22139 2283 8551	13196	-0.011	0.1538	No
100	PDE7B	19807	13454	-0.013	0.1401	No
101	NPR2	16230	13548	-0.014	0.1353	No
102	PDE3B	5236	14060	-0.020	0.1079	No
103	PDE6H	17257	14303	-0.025	0.0951	No
104	NT5C1B	21315	14335	-0.025	0.0937	No
105	CANT1	13304	14557	-0.030	0.0822	No
106	PDE2A	18170	14997	-0.046	0.0590	No
107	GMPR2	2711	15495	-0.077	0.0331	No
108	PDE4B	9543	15605	-0.087	0.0282	No
109	PDE4C	8481	15670	-0.094	0.0260	No
110	PKM2	3642 9573	15846	-0.120	0.0180	No
111	PDE4D	10722 6235	15879	-0.126	0.0178	No
112	ADCY9	22680	16224	-0.197	0.0017	No
113	FHIT	21920	16253	-0.205	0.0027	No
114	ADCY7	8552 448	16270	-0.208	0.0045	No
115	PAPSS1	15419	16295	-0.214	0.0058	No
116	GMPR	21651	16434	-0.254	0.0016	No
117	NT5C	20151	16651	-0.327	-0.0060	No
118	NT5C2	3768 8052	16811	-0.374	-0.0100	No
119	HPRT1	2655 24339 408	17022	-0.453	-0.0157	No
120	DGUOK	17099 1041	17034	-0.459	-0.0105	No
121	POLE4	12441	17037	-0.460	-0.0049	No
122	ZNRD1	1491 22987	17058	-0.468	-0.0001	No
123	ENTPD5	4497	17182	-0.520	-0.0003	No
124	POLD1	17847	17231	-0.537	0.0038	No
125	AK2	8563 2479 16073	17531	-0.720	-0.0033	No
126	PDE7A	9544 1788	17634	-0.780	0.0009	No
127	DCK	16808	17693	-0.826	0.0081	No
128	ADSSL1	21136 2087	18112	-1.256	0.0012	No
129	POLD4	12822	18434	-2.084	0.0098	No