Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | REACTOME_PURINE_METABOLISM |
| Enrichment Score (ES) | 0.8342264 |
| Normalized Enrichment Score (NES) | 1.6092316 |
| Nominal p-value | 0.0018450185 |
| FDR q-value | 0.022051694 |
| FWER p-Value | 0.239 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | APRT | 8620 | 95 | 2.643 | 0.0626 | Yes | ||
| 2 | GART | 22543 1754 | 107 | 2.575 | 0.1280 | Yes | ||
| 3 | ATIC | 14231 3968 | 108 | 2.568 | 0.1938 | Yes | ||
| 4 | NP | 22027 9597 5273 5274 | 123 | 2.541 | 0.2581 | Yes | ||
| 5 | NME2 | 9468 | 150 | 2.439 | 0.3192 | Yes | ||
| 6 | ADA | 2703 14361 | 236 | 2.017 | 0.3663 | Yes | ||
| 7 | IMPDH2 | 10730 | 254 | 1.927 | 0.4148 | Yes | ||
| 8 | ATP5G1 | 8636 | 270 | 1.873 | 0.4619 | Yes | ||
| 9 | NME1 | 9467 | 273 | 1.870 | 0.5098 | Yes | ||
| 10 | PPAT | 6081 | 274 | 1.868 | 0.5576 | Yes | ||
| 11 | RRM2 | 5401 5400 | 303 | 1.762 | 0.6012 | Yes | ||
| 12 | GUK1 | 20432 | 335 | 1.679 | 0.6426 | Yes | ||
| 13 | ADSL | 4358 | 398 | 1.551 | 0.6790 | Yes | ||
| 14 | ATP5J | 880 22555 | 462 | 1.432 | 0.7123 | Yes | ||
| 15 | PAICS | 16820 | 542 | 1.323 | 0.7419 | Yes | ||
| 16 | RRM1 | 18163 | 718 | 1.089 | 0.7604 | Yes | ||
| 17 | GMPS | 15578 | 748 | 1.059 | 0.7860 | Yes | ||
| 18 | IMPDH1 | 17197 1131 | 1244 | 0.683 | 0.7768 | Yes | ||
| 19 | ATP5J2 | 12186 | 1324 | 0.629 | 0.7887 | Yes | ||
| 20 | ATP5I | 8637 | 1337 | 0.623 | 0.8040 | Yes | ||
| 21 | ATP5A1 | 23505 | 1360 | 0.613 | 0.8185 | Yes | ||
| 22 | ATP5O | 22539 | 1361 | 0.613 | 0.8342 | Yes | ||
| 23 | ATP5H | 12948 | 2186 | 0.294 | 0.7974 | No | ||
| 24 | ATP5E | 14321 | 2451 | 0.224 | 0.7890 | No | ||
| 25 | ATP5F1 | 15212 | 2692 | 0.168 | 0.7803 | No | ||
| 26 | TXNRD1 | 19923 | 2839 | 0.137 | 0.7760 | No | ||
| 27 | ATP5D | 19949 | 3140 | 0.092 | 0.7622 | No | ||
| 28 | AMPD2 | 1931 15197 | 6243 | 0.011 | 0.5955 | No | ||
| 29 | XDH | 22897 | 7805 | 0.005 | 0.5116 | No | ||
| 30 | AK1 | 4363 | 8517 | 0.003 | 0.4734 | No | ||
| 31 | ADK | 3302 3454 8555 | 9399 | 0.001 | 0.4260 | No | ||
| 32 | AMPD3 | 4383 2110 | 11808 | -0.005 | 0.2965 | No | ||
| 33 | AMPD1 | 5051 | 12802 | -0.009 | 0.2433 | No | ||
| 34 | ATP5B | 19846 | 14963 | -0.044 | 0.1282 | No | ||
| 35 | ATP5C1 | 8635 | 15830 | -0.118 | 0.0846 | No | ||
| 36 | NT5C2 | 3768 8052 | 16811 | -0.374 | 0.0414 | No | ||
| 37 | HPRT1 | 2655 24339 408 | 17022 | -0.453 | 0.0418 | No | ||
| 38 | DGUOK | 17099 1041 | 17034 | -0.459 | 0.0529 | No | ||
| 39 | ADSSL1 | 21136 2087 | 18112 | -1.256 | 0.0271 | No |
