Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | REACTOME_DIABETES_PATHWAYS |
Enrichment Score (ES) | 0.71338934 |
Normalized Enrichment Score (NES) | 1.716104 |
Nominal p-value | 0.0 |
FDR q-value | 0.008214543 |
FWER p-Value | 0.0090 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RPL38 | 12562 20606 7475 | 0 | 8.590 | 0.1250 | Yes | ||
2 | NDUFC1 | 7287 12339 | 6 | 5.803 | 0.2091 | Yes | ||
3 | SEC61B | 12305 7266 | 62 | 3.027 | 0.2501 | Yes | ||
4 | GNAS | 9025 2963 2752 | 131 | 2.517 | 0.2831 | Yes | ||
5 | RPL27A | 11181 6467 18130 | 143 | 2.448 | 0.3181 | Yes | ||
6 | ATP5G1 | 8636 | 270 | 1.873 | 0.3385 | Yes | ||
7 | NDUFS3 | 7553 12683 | 355 | 1.650 | 0.3580 | Yes | ||
8 | ATP5J | 880 22555 | 462 | 1.432 | 0.3730 | Yes | ||
9 | UQCR | 12382 | 547 | 1.318 | 0.3877 | Yes | ||
10 | IGFBP4 | 20670 9160 | 636 | 1.192 | 0.4002 | Yes | ||
11 | TPI1 | 5795 10212 | 724 | 1.085 | 0.4113 | Yes | ||
12 | RPS24 | 5399 | 764 | 1.046 | 0.4244 | Yes | ||
13 | IDH3A | 19447 | 806 | 1.016 | 0.4370 | Yes | ||
14 | NDUFB3 | 12362 | 833 | 0.990 | 0.4500 | Yes | ||
15 | MDH2 | 9399 | 934 | 0.895 | 0.4576 | Yes | ||
16 | NDUFA9 | 12288 | 995 | 0.842 | 0.4666 | Yes | ||
17 | COX6C | 8775 | 997 | 0.841 | 0.4787 | Yes | ||
18 | NDUFA10 | 7420 | 1012 | 0.836 | 0.4901 | Yes | ||
19 | DDOST | 16021 | 1025 | 0.827 | 0.5015 | Yes | ||
20 | RPS2 | 9279 | 1069 | 0.794 | 0.5107 | Yes | ||
21 | RPL14 | 19267 | 1073 | 0.792 | 0.5221 | Yes | ||
22 | RPL4 | 7499 19411 | 1082 | 0.785 | 0.5331 | Yes | ||
23 | CYCS | 8821 | 1104 | 0.771 | 0.5432 | Yes | ||
24 | COX7B | 7260 | 1152 | 0.739 | 0.5514 | Yes | ||
25 | NDUFA7 | 12347 | 1154 | 0.738 | 0.5621 | Yes | ||
26 | RPLP2 | 7401 | 1183 | 0.722 | 0.5710 | Yes | ||
27 | UQCRB | 12545 | 1196 | 0.715 | 0.5808 | Yes | ||
28 | RPS19 | 5398 | 1201 | 0.713 | 0.5910 | Yes | ||
29 | NDUFV1 | 23953 | 1286 | 0.652 | 0.5959 | Yes | ||
30 | SLC30A7 | 15186 | 1314 | 0.636 | 0.6037 | Yes | ||
31 | ATP5J2 | 12186 | 1324 | 0.629 | 0.6123 | Yes | ||
32 | ATP5I | 8637 | 1337 | 0.623 | 0.6207 | Yes | ||
33 | ETFB | 18279 | 1342 | 0.621 | 0.6296 | Yes | ||
34 | NDUFA8 | 14605 | 1344 | 0.621 | 0.6385 | Yes | ||
35 | COX7C | 8776 | 1355 | 0.616 | 0.6469 | Yes | ||
36 | ATP5A1 | 23505 | 1360 | 0.613 | 0.6557 | Yes | ||
37 | ATP5O | 22539 | 1361 | 0.613 | 0.6646 | Yes | ||
38 | RPL6 | 9747 | 1385 | 0.599 | 0.6720 | Yes | ||
39 | NDUFS7 | 19946 | 1515 | 0.538 | 0.6729 | Yes | ||
40 | NDUFS5 | 9296 | 1539 | 0.530 | 0.6793 | Yes | ||
41 | SDHD | 19125 | 1692 | 0.461 | 0.6778 | Yes | ||
42 | UQCRC2 | 18102 | 1800 | 0.419 | 0.6781 | Yes | ||
43 | COX6B1 | 4283 8479 | 1821 | 0.412 | 0.6830 | Yes | ||
44 | EXOC8 | 4161 | 1842 | 0.404 | 0.6878 | Yes | ||
45 | NDUFB5 | 12277 | 1859 | 0.398 | 0.6927 | Yes | ||
46 | NDUFC2 | 18183 | 1873 | 0.394 | 0.6977 | Yes | ||
47 | RPS23 | 12352 | 1899 | 0.385 | 0.7020 | Yes | ||
48 | NDUFA4 | 9451 | 1928 | 0.375 | 0.7059 | Yes | ||
49 | SSR4 | 24303 5519 | 2017 | 0.347 | 0.7062 | Yes | ||
50 | ETFDH | 15313 | 2058 | 0.335 | 0.7089 | Yes | ||
51 | NDUFB7 | 12429 | 2129 | 0.309 | 0.7096 | Yes | ||
52 | SSR2 | 15549 | 2143 | 0.307 | 0.7134 | Yes | ||
53 | COX6A1 | 8774 4553 | 2264 | 0.271 | 0.7108 | No | ||
54 | NDUFA2 | 9450 | 2346 | 0.253 | 0.7101 | No | ||
55 | IDH3G | 24132 | 2400 | 0.238 | 0.7107 | No | ||
56 | ATP5E | 14321 | 2451 | 0.224 | 0.7113 | No | ||
57 | SRP72 | 16819 | 2533 | 0.205 | 0.7099 | No | ||
58 | NDUFB8 | 7418 | 2579 | 0.196 | 0.7103 | No | ||
59 | NDUFAB1 | 7667 | 2610 | 0.189 | 0.7114 | No | ||
60 | ATP5F1 | 15212 | 2692 | 0.168 | 0.7094 | No | ||
61 | NDUFS4 | 9452 5157 3173 | 2864 | 0.133 | 0.7021 | No | ||
62 | NDUFS2 | 4089 13760 | 2866 | 0.133 | 0.7040 | No | ||
63 | RPS3A | 9755 | 2908 | 0.125 | 0.7036 | No | ||
64 | RPS15A | 6476 | 3011 | 0.108 | 0.6996 | No | ||
65 | ATP5D | 19949 | 3140 | 0.092 | 0.6940 | No | ||
66 | RPS17 | 9753 | 3227 | 0.083 | 0.6906 | No | ||
67 | RPS14 | 9751 | 3282 | 0.079 | 0.6888 | No | ||
68 | ATF4 | 22417 2239 | 3287 | 0.078 | 0.6897 | No | ||
69 | F2 | 14524 | 3326 | 0.074 | 0.6888 | No | ||
70 | SEC61G | 9795 | 3386 | 0.069 | 0.6866 | No | ||
71 | RPS3 | 6549 11295 | 3415 | 0.067 | 0.6860 | No | ||
72 | ABCC8 | 9941 11649 | 3547 | 0.060 | 0.6798 | No | ||
73 | RPL41 | 12611 | 3724 | 0.051 | 0.6710 | No | ||
74 | NDUFB10 | 23084 | 3741 | 0.050 | 0.6709 | No | ||
75 | PFKFB2 | 4116 5242 | 3932 | 0.043 | 0.6612 | No | ||
76 | KLK3 | 16337 | 4066 | 0.039 | 0.6546 | No | ||
77 | RPL8 | 22437 | 4085 | 0.038 | 0.6541 | No | ||
78 | RPL27 | 9740 | 4272 | 0.033 | 0.6445 | No | ||
79 | CS | 19839 | 4292 | 0.033 | 0.6440 | No | ||
80 | RPL19 | 9736 | 4906 | 0.022 | 0.6111 | No | ||
81 | EIF2S1 | 4658 | 4978 | 0.021 | 0.6076 | No | ||
82 | GLP1R | 23304 | 5171 | 0.019 | 0.5974 | No | ||
83 | SDHB | 2348 12566 14880 | 5373 | 0.017 | 0.5868 | No | ||
84 | KCNJ11 | 17822 | 5388 | 0.017 | 0.5863 | No | ||
85 | RPS4X | 9756 | 5617 | 0.015 | 0.5742 | No | ||
86 | CTSL1 | 4574 | 5647 | 0.015 | 0.5728 | No | ||
87 | CPE | 18868 | 5837 | 0.013 | 0.5628 | No | ||
88 | EXOC5 | 8370 | 5905 | 0.013 | 0.5593 | No | ||
89 | RPL37 | 12502 7421 22521 | 5908 | 0.013 | 0.5594 | No | ||
90 | RAP1A | 8467 | 6033 | 0.012 | 0.5529 | No | ||
91 | IGF1 | 3352 9156 3409 | 6416 | 0.010 | 0.5323 | No | ||
92 | PGK1 | 9557 5244 | 6489 | 0.010 | 0.5286 | No | ||
93 | NDUFB4 | 22596 7541 | 6529 | 0.010 | 0.5266 | No | ||
94 | SYT5 | 17986 | 6688 | 0.009 | 0.5182 | No | ||
95 | ERN1 | 8137 | 6695 | 0.009 | 0.5180 | No | ||
96 | ADRA2A | 4355 | 6724 | 0.009 | 0.5166 | No | ||
97 | RPL18 | 450 5390 | 7542 | 0.006 | 0.4724 | No | ||
98 | IGFBP1 | 20948 | 7988 | 0.005 | 0.4484 | No | ||
99 | SRP19 | 2004 12341 | 8166 | 0.004 | 0.4388 | No | ||
100 | SLC2A2 | 15623 1880 1855 | 8276 | 0.004 | 0.4330 | No | ||
101 | NKX2-2 | 5176 | 9308 | 0.001 | 0.3771 | No | ||
102 | PLA2G7 | 23233 | 9373 | 0.001 | 0.3737 | No | ||
103 | PDX1 | 16621 | 9626 | 0.001 | 0.3601 | No | ||
104 | RPL17 | 11429 6653 | 9669 | 0.001 | 0.3578 | No | ||
105 | GCG | 14578 | 9789 | 0.000 | 0.3513 | No | ||
106 | KIF5B | 4955 2031 | 9793 | 0.000 | 0.3512 | No | ||
107 | SDHA | 12436 | 9969 | -0.000 | 0.3417 | No | ||
108 | MMP2 | 18525 | 10110 | -0.000 | 0.3341 | No | ||
109 | RPSA | 19270 4984 | 10413 | -0.001 | 0.3178 | No | ||
110 | IGFBP5 | 4899 | 10506 | -0.001 | 0.3128 | No | ||
111 | PRKAR2B | 5288 2107 | 11006 | -0.003 | 0.2858 | No | ||
112 | IGFALS | 9158 | 11487 | -0.004 | 0.2599 | No | ||
113 | RPS13 | 12633 | 11876 | -0.005 | 0.2389 | No | ||
114 | MBTPS1 | 18730 3809 3770 | 11960 | -0.005 | 0.2345 | No | ||
115 | SRP54 | 6282 | 12262 | -0.007 | 0.2183 | No | ||
116 | CHRM3 | 21547 | 12438 | -0.007 | 0.2089 | No | ||
117 | LEP | 17505 | 12934 | -0.010 | 0.1823 | No | ||
118 | UQCRC1 | 10259 | 12986 | -0.010 | 0.1796 | No | ||
119 | IGFBP6 | 9161 | 13025 | -0.010 | 0.1777 | No | ||
120 | UQCRFS1 | 21499 | 13789 | -0.017 | 0.1366 | No | ||
121 | FFAR1 | 10583 | 14020 | -0.019 | 0.1245 | No | ||
122 | PFKFB1 | 9552 | 14050 | -0.020 | 0.1232 | No | ||
123 | KLF4 | 9230 4962 4963 | 14128 | -0.021 | 0.1193 | No | ||
124 | PCSK2 | 9537 5231 14824 | 14330 | -0.025 | 0.1088 | No | ||
125 | RPS16 | 9752 | 14514 | -0.029 | 0.0993 | No | ||
126 | COX4I1 | 18444 | 14606 | -0.032 | 0.0948 | No | ||
127 | RPS5 | 18391 | 14794 | -0.038 | 0.0852 | No | ||
128 | RPL5 | 9746 | 14925 | -0.042 | 0.0788 | No | ||
129 | ATP5B | 19846 | 14963 | -0.044 | 0.0775 | No | ||
130 | FAU | 8954 | 15013 | -0.046 | 0.0755 | No | ||
131 | RPS29 | 9754 | 15018 | -0.046 | 0.0759 | No | ||
132 | COX5B | 4552 | 15362 | -0.066 | 0.0583 | No | ||
133 | RPL28 | 5392 | 15681 | -0.095 | 0.0425 | No | ||
134 | RPL39 | 12496 | 15742 | -0.102 | 0.0407 | No | ||
135 | RPS21 | 12356 | 15776 | -0.108 | 0.0405 | No | ||
136 | RPLP1 | 3010 | 15793 | -0.111 | 0.0412 | No | ||
137 | RPL18A | 13358 | 15800 | -0.112 | 0.0425 | No | ||
138 | ATP5C1 | 8635 | 15830 | -0.118 | 0.0427 | No | ||
139 | PKM2 | 3642 9573 | 15846 | -0.120 | 0.0436 | No | ||
140 | RPS20 | 7438 | 15905 | -0.129 | 0.0424 | No | ||
141 | RPS28 | 12009 | 15921 | -0.130 | 0.0434 | No | ||
142 | SEC11A | 12144 | 15922 | -0.131 | 0.0453 | No | ||
143 | NDUFS8 | 23950 | 15933 | -0.133 | 0.0467 | No | ||
144 | HSPA5 | 9045 | 16036 | -0.154 | 0.0434 | No | ||
145 | RPL37A | 9744 | 16068 | -0.161 | 0.0441 | No | ||
146 | NFYA | 5172 | 16184 | -0.187 | 0.0406 | No | ||
147 | NDUFA11 | 12832 | 16228 | -0.198 | 0.0411 | No | ||
148 | RPL11 | 12450 | 16276 | -0.209 | 0.0416 | No | ||
149 | VAMP2 | 20826 | 16297 | -0.215 | 0.0437 | No | ||
150 | COX8A | 8777 | 16403 | -0.243 | 0.0415 | No | ||
151 | PDHA1 | 24020 | 16583 | -0.302 | 0.0362 | No | ||
152 | NDUFA6 | 12473 | 16588 | -0.303 | 0.0404 | No | ||
153 | RPS25 | 13270 | 16642 | -0.323 | 0.0422 | No | ||
154 | IQGAP1 | 6619 | 16674 | -0.333 | 0.0454 | No | ||
155 | SRP14 | 9894 | 16701 | -0.341 | 0.0490 | No | ||
156 | PRKCA | 20174 | 17118 | -0.497 | 0.0337 | No | ||
157 | DLD | 2097 21090 | 17631 | -0.777 | 0.0172 | No | ||
158 | OGDH | 9502 1412 | 18043 | -1.165 | 0.0119 | No | ||
159 | SUCLG1 | 17409 1059 | 18152 | -1.312 | 0.0251 | No |