Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | NETPATH_BCR |
Enrichment Score (ES) | -0.6811128 |
Normalized Enrichment Score (NES) | -1.6023363 |
Nominal p-value | 0.0 |
FDR q-value | 0.04249215 |
FWER p-Value | 0.408 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTK2 | 22271 | 48 | 3.276 | 0.0408 | No | ||
2 | DOK3 | 3229 21451 | 117 | 2.548 | 0.0709 | No | ||
3 | BLNK | 23681 3691 | 325 | 1.702 | 0.0822 | No | ||
4 | PPP3CA | 1863 5284 | 472 | 1.412 | 0.0931 | No | ||
5 | CCNE1 | 17857 | 561 | 1.308 | 0.1056 | No | ||
6 | BAX | 17832 | 1000 | 0.840 | 0.0931 | No | ||
7 | CYCS | 8821 | 1104 | 0.771 | 0.0977 | No | ||
8 | RPS6 | 9757 | 1413 | 0.582 | 0.0888 | No | ||
9 | BCAR1 | 18741 | 1602 | 0.499 | 0.0852 | No | ||
10 | MAP3K7 | 16255 | 1728 | 0.446 | 0.0844 | No | ||
11 | MAPK8 | 6459 | 1918 | 0.379 | 0.0792 | No | ||
12 | CDK2 | 3438 3373 19592 3322 | 2093 | 0.323 | 0.0741 | No | ||
13 | CDK4 | 3424 19859 | 2258 | 0.274 | 0.0688 | No | ||
14 | CHUK | 23665 | 2349 | 0.253 | 0.0673 | No | ||
15 | CCNA2 | 15357 | 2478 | 0.217 | 0.0633 | No | ||
16 | IKBKB | 4907 | 2832 | 0.138 | 0.0460 | No | ||
17 | BCL2L11 | 2790 14861 | 3239 | 0.082 | 0.0252 | No | ||
18 | CDK6 | 16600 | 3594 | 0.058 | 0.0068 | No | ||
19 | PIK3R2 | 18850 | 3916 | 0.043 | -0.0100 | No | ||
20 | SHC1 | 9813 9812 5430 | 3966 | 0.042 | -0.0121 | No | ||
21 | AKT1 | 8568 | 4238 | 0.034 | -0.0263 | No | ||
22 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 4399 | 0.030 | -0.0345 | No | ||
23 | FYN | 3375 3395 20052 | 5080 | 0.020 | -0.0710 | No | ||
24 | ITK | 4934 | 5203 | 0.019 | -0.0773 | No | ||
25 | CD5 | 23741 | 5237 | 0.019 | -0.0789 | No | ||
26 | ACTR3 | 13166 | 7080 | 0.008 | -0.1783 | No | ||
27 | MAPK4 | 23409 | 7549 | 0.006 | -0.2036 | No | ||
28 | NCK1 | 9447 5152 | 7822 | 0.005 | -0.2182 | No | ||
29 | PRKCE | 9575 | 7917 | 0.005 | -0.2232 | No | ||
30 | PTPN11 | 5326 16391 9660 | 9360 | 0.001 | -0.3011 | No | ||
31 | ACTR2 | 20523 | 9444 | 0.001 | -0.3056 | No | ||
32 | CDK7 | 21365 | 9956 | -0.000 | -0.3332 | No | ||
33 | LYN | 16281 | 10463 | -0.001 | -0.3605 | No | ||
34 | CR2 | 3942 13707 | 10585 | -0.002 | -0.3671 | No | ||
35 | RPS6KA1 | 15725 | 10766 | -0.002 | -0.3768 | No | ||
36 | PPP3R1 | 9611 489 | 11660 | -0.005 | -0.4250 | No | ||
37 | NFATC2 | 5168 2866 | 11816 | -0.005 | -0.4333 | No | ||
38 | IKBKG | 2570 2562 4908 | 11885 | -0.005 | -0.4369 | No | ||
39 | DOK1 | 17104 1018 1177 | 12045 | -0.006 | -0.4454 | No | ||
40 | DAPP1 | 11159 6445 6446 | 12268 | -0.007 | -0.4573 | No | ||
41 | PIK3R1 | 3170 | 12501 | -0.008 | -0.4698 | No | ||
42 | GAB2 | 1821 18184 2025 | 12547 | -0.008 | -0.4721 | No | ||
43 | PLCG1 | 14753 | 12673 | -0.009 | -0.4787 | No | ||
44 | SOS1 | 5476 | 13043 | -0.010 | -0.4985 | No | ||
45 | ATF2 | 4418 2759 | 13658 | -0.015 | -0.5315 | No | ||
46 | PRKD1 | 2074 21075 | 13717 | -0.016 | -0.5344 | No | ||
47 | CRK | 4559 1249 | 14123 | -0.021 | -0.5561 | No | ||
48 | PIP5K1C | 5250 19929 | 14310 | -0.025 | -0.5658 | No | ||
49 | CREB1 | 3990 8782 4558 4093 | 14348 | -0.026 | -0.5674 | No | ||
50 | LCP2 | 4988 9268 | 14492 | -0.028 | -0.5748 | No | ||
51 | ZAP70 | 14271 4042 | 14520 | -0.029 | -0.5759 | No | ||
52 | CBL | 19154 | 14583 | -0.031 | -0.5788 | No | ||
53 | PRKCQ | 2873 2831 | 14804 | -0.038 | -0.5902 | No | ||
54 | GSK3A | 405 | 14904 | -0.042 | -0.5950 | No | ||
55 | VAV2 | 5848 2670 | 14953 | -0.044 | -0.5970 | No | ||
56 | PDK2 | 20285 | 15054 | -0.048 | -0.6018 | No | ||
57 | RAPGEF1 | 4218 2860 | 15195 | -0.056 | -0.6086 | No | ||
58 | CASP9 | 16001 2410 2458 | 15500 | -0.077 | -0.6240 | No | ||
59 | PTPRC | 5327 9662 | 15526 | -0.080 | -0.6243 | No | ||
60 | RPS6KB1 | 7815 1207 13040 | 15680 | -0.094 | -0.6313 | No | ||
61 | ITPR2 | 9194 | 15689 | -0.095 | -0.6305 | No | ||
62 | HCK | 14787 | 15924 | -0.131 | -0.6414 | No | ||
63 | REL | 9716 | 16118 | -0.172 | -0.6495 | No | ||
64 | CASP7 | 23826 | 16207 | -0.193 | -0.6517 | No | ||
65 | LCK | 15746 | 16281 | -0.210 | -0.6529 | No | ||
66 | MAP4K1 | 18313 | 16615 | -0.312 | -0.6668 | No | ||
67 | RASA1 | 10174 | 16776 | -0.365 | -0.6706 | No | ||
68 | PIK3AP1 | 23679 | 16827 | -0.380 | -0.6682 | No | ||
69 | PRKCD | 21897 | 17066 | -0.470 | -0.6749 | Yes | ||
70 | SOS2 | 21049 | 17109 | -0.492 | -0.6706 | Yes | ||
71 | TEC | 16514 | 17142 | -0.506 | -0.6657 | Yes | ||
72 | MAPK14 | 23313 | 17215 | -0.531 | -0.6625 | Yes | ||
73 | RASGRP3 | 10767 | 17270 | -0.560 | -0.6580 | Yes | ||
74 | CARD11 | 8436 | 17271 | -0.561 | -0.6506 | Yes | ||
75 | CRKL | 4560 | 17368 | -0.613 | -0.6476 | Yes | ||
76 | GRB2 | 20149 | 17370 | -0.613 | -0.6396 | Yes | ||
77 | GSK3B | 22761 | 17375 | -0.618 | -0.6316 | Yes | ||
78 | MAPK3 | 6458 11170 | 17396 | -0.634 | -0.6243 | Yes | ||
79 | SH3BP2 | 16874 | 17428 | -0.656 | -0.6173 | Yes | ||
80 | JUN | 15832 | 17458 | -0.677 | -0.6099 | Yes | ||
81 | CD19 | 17640 | 17470 | -0.683 | -0.6014 | Yes | ||
82 | RB1 | 21754 | 17480 | -0.690 | -0.5927 | Yes | ||
83 | CD22 | 17881 | 17526 | -0.717 | -0.5857 | Yes | ||
84 | NFATC3 | 5169 | 17539 | -0.726 | -0.5767 | Yes | ||
85 | CCND2 | 16987 | 17575 | -0.744 | -0.5688 | Yes | ||
86 | BTK | 24061 | 17622 | -0.771 | -0.5610 | Yes | ||
87 | CD81 | 8719 | 17641 | -0.785 | -0.5516 | Yes | ||
88 | PTPN18 | 14279 | 17668 | -0.805 | -0.5423 | Yes | ||
89 | RELA | 23783 | 17734 | -0.859 | -0.5345 | Yes | ||
90 | HDAC5 | 1480 20205 | 17852 | -0.961 | -0.5281 | Yes | ||
91 | SYK | 21636 | 17870 | -0.978 | -0.5160 | Yes | ||
92 | BCL10 | 15397 | 17878 | -0.984 | -0.5034 | Yes | ||
93 | HCLS1 | 22770 | 17897 | -1.003 | -0.4911 | Yes | ||
94 | VAV1 | 23173 | 17925 | -1.033 | -0.4788 | Yes | ||
95 | WAS | 24193 | 17956 | -1.065 | -0.4663 | Yes | ||
96 | LAT2 | 16351 | 18003 | -1.110 | -0.4541 | Yes | ||
97 | CBLB | 5531 22734 | 18038 | -1.159 | -0.4406 | Yes | ||
98 | FCGR2B | 8959 | 18041 | -1.163 | -0.4253 | Yes | ||
99 | CD79B | 20185 1309 | 18046 | -1.168 | -0.4100 | Yes | ||
100 | GAB1 | 18828 | 18101 | -1.234 | -0.3966 | Yes | ||
101 | CCND3 | 4489 4490 | 18115 | -1.258 | -0.3807 | Yes | ||
102 | PTK2B | 21776 | 18118 | -1.260 | -0.3641 | Yes | ||
103 | PDPK1 | 23097 | 18147 | -1.308 | -0.3483 | Yes | ||
104 | NFKBIA | 21065 | 18148 | -1.309 | -0.3309 | Yes | ||
105 | CSK | 8805 | 18193 | -1.378 | -0.3150 | Yes | ||
106 | CD79A | 18342 | 18218 | -1.423 | -0.2975 | Yes | ||
107 | MAPKAPK2 | 13838 | 18261 | -1.536 | -0.2794 | Yes | ||
108 | BLK | 3205 21791 | 18473 | -2.331 | -0.2599 | Yes | ||
109 | NEDD9 | 3206 21483 | 18496 | -2.487 | -0.2282 | Yes | ||
110 | GTF2I | 16353 5491 9863 3280 3184 | 18499 | -2.501 | -0.1951 | Yes | ||
111 | PTPN6 | 17002 | 18512 | -2.552 | -0.1620 | Yes | ||
112 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 18532 | -2.758 | -0.1265 | Yes | ||
113 | BCL6 | 22624 | 18554 | -3.046 | -0.0872 | Yes | ||
114 | CD72 | 8718 | 18566 | -3.281 | -0.0444 | Yes | ||
115 | MAPK1 | 1642 11167 | 18573 | -3.548 | 0.0023 | Yes |