Details for gene set V$SREBP1

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	V$SREBP1_Q6
Enrichment Score (ES)	-0.5516919
Normalized Enrichment Score (NES)	-1.427122
Nominal p-value	0.0080
FDR q-value	0.63748753
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PPP1R10	110136 3170725 3610484	77	1.334	0.0294	No
2	EIF4G2	3800575 6860184	94	1.204	0.0588	No
3	PIAS1	5340301	305	0.780	0.0671	No
4	EMP1	4120438	432	0.662	0.0769	No
5	FCHSD2	5720092	510	0.615	0.0882	No
6	KPNB1	1690138	543	0.602	0.1016	No
7	ATP6V1A	6590242	739	0.493	0.1035	No
8	MMP14	670079	776	0.481	0.1136	No
9	NSF	4070075	834	0.456	0.1220	No
10	NMT1	5810152	868	0.444	0.1314	No
11	PDCD10	4760500	982	0.404	0.1354	No
12	DDX6	2630025 6770408	1247	0.323	0.1293	No
13	NFIX	2450152	1365	0.289	0.1302	No
14	ZFYVE1	60440	1366	0.289	0.1375	No
15	SLIT3	7100132	1419	0.273	0.1415	No
16	ANP32A	510044 1580095 2680037	1462	0.264	0.1459	No
17	JUP	2510671	1600	0.233	0.1444	No
18	SIPA1L2	4850731	2031	0.163	0.1251	No
19	RBX1	2120010 2340047	2049	0.160	0.1282	No
20	LASP1	1690528 2190341 6420341	2056	0.159	0.1319	No
21	NFAT5	2510411 5890195 6550152	2188	0.140	0.1283	No
22	YWHAQ	6760524	2442	0.112	0.1174	No
23	MYH10	2640673	2489	0.107	0.1176	No
24	PHF15	6550066 6860673	2692	0.090	0.1089	No
25	STX1A	3060273	2768	0.084	0.1070	No
26	TRERF1	6370017 6940138	2775	0.084	0.1088	No
27	NTRK3	4050687 4070167 4610026 6100484	2796	0.083	0.1098	No
28	FXYD1	1400239 6560129	2881	0.076	0.1071	No
29	DYRK1A	3190181	2922	0.073	0.1068	No
30	EN1	5360168 7050025	2979	0.069	0.1055	No
31	MAPKAPK3	630520	3034	0.066	0.1042	No
32	PACSIN3	4540369 4540400 5360037 6940129	3071	0.063	0.1039	No
33	PCF11	1240180	3114	0.061	0.1031	No
34	FBS1	2570520	3129	0.060	0.1039	No
35	B4GALT2	780037	3164	0.057	0.1035	No
36	GPR85	5130750 5910020	3178	0.056	0.1042	No
37	SLC39A14	670300 1400093 1990711	3304	0.050	0.0986	No
38	REL	360707	3352	0.048	0.0973	No
39	ZIC4	1500082	3443	0.044	0.0935	No
40	BAZ2A	730184	3525	0.041	0.0902	No
41	CLDN5	6510717	3609	0.038	0.0866	No
42	CLASP1	6860279	3615	0.037	0.0873	No
43	SOX12	1780037	4005	0.026	0.0668	No
44	ENO2	2320068	4193	0.023	0.0573	No
45	TRAF4	3060041 4920528 6980286	4197	0.023	0.0577	No
46	DSG4	3990605 6400736	4254	0.022	0.0552	No
47	POU4F2	2120195 2570022	4288	0.021	0.0539	No
48	LRP8	3610746 5360035	4294	0.021	0.0542	No
49	RARG	6760136	4390	0.020	0.0495	No
50	SREBF2	3390692	4495	0.018	0.0444	No
51	KIF1B	1240494 2370139 4570270 6510102	4683	0.016	0.0346	No
52	TEAD2	6450079	4929	0.013	0.0217	No
53	DHH	2120433	5017	0.012	0.0172	No
54	MEOX2	6400288	5061	0.012	0.0152	No
55	KCNN3	6520600 6420138	5093	0.012	0.0138	No
56	SLC4A1	6290577	5174	0.011	0.0098	No
57	CACNA1D	1740315 4730731	5188	0.011	0.0094	No
58	SLC4A10	2060670	5558	0.009	-0.0104	No
59	LIN28	6590672	5827	0.007	-0.0248	No
60	SLC24A1	1240463	5846	0.007	-0.0256	No
61	GUCA2B	4200014	5890	0.007	-0.0277	No
62	TCF2	870338 5050632	5950	0.007	-0.0308	No
63	GAP43	3130504	5970	0.007	-0.0316	No
64	GRIA1	1340152 3780750 4920440	5971	0.007	-0.0315	No
65	GFAP	2060092	6098	0.006	-0.0382	No
66	GRID2	2680242	6135	0.006	-0.0400	No
67	DUSP8	6650039	6350	0.005	-0.0514	No
68	EMX2	1660092	6392	0.005	-0.0535	No
69	SERPINI1	2940468	6406	0.005	-0.0541	No
70	SIX4	6760022	6443	0.005	-0.0560	No
71	HYAL1	3850341	6575	0.004	-0.0630	No
72	PLA2G3	5130739	6690	0.004	-0.0691	No
73	GNAO1	2510292 6590487	6776	0.003	-0.0736	No
74	CACNB1	2940427 3710487	6940	0.003	-0.0824	No
75	SALL1	5420020 7050195	6957	0.003	-0.0832	No
76	SLC2A4	540441	7048	0.002	-0.0880	No
77	PAX3	50551	7370	0.001	-0.1053	No
78	ZFP36L1	2510138 4120048	7959	-0.000	-0.1372	No
79	HOXD10	6100039	8239	-0.001	-0.1523	No
80	KCNMB1	4760139	8300	-0.001	-0.1556	No
81	ESR1	4060372 5860193	8509	-0.002	-0.1668	No
82	ANXA9	1190195	8616	-0.002	-0.1725	No
83	PDE5A	130072	8798	-0.003	-0.1822	No
84	LRRN1	3290154	8811	-0.003	-0.1828	No
85	TIMP4	6110433	8886	-0.003	-0.1868	No
86	NF1	6980433	8907	-0.003	-0.1878	No
87	EVX1	1980471	9097	-0.003	-0.1979	No
88	NFATC4	2470735	9153	-0.004	-0.2008	No
89	FABP6	7000278	9226	-0.004	-0.2046	No
90	LMX1A	2810239 5690324	9369	-0.004	-0.2122	No
91	GREM1	3940180	9711	-0.005	-0.2306	No
92	HOXA11	6980133	9741	-0.005	-0.2320	No
93	HIF1A	5670605	9774	-0.005	-0.2336	No
94	FBXO24	1230132 4610121	9851	-0.006	-0.2376	No
95	ERF	110551 1770278	9994	-0.006	-0.2452	No
96	HOXC4	1940193	10060	-0.006	-0.2485	No
97	RKHD3	6180471	10664	-0.009	-0.2810	No
98	FADS3	3120079	11063	-0.010	-0.3023	No
99	CRLF1	3520092	11133	-0.011	-0.3058	No
100	PTRF	2260204	11165	-0.011	-0.3072	No
101	ATP6V0C	1780609	11525	-0.013	-0.3264	No
102	AGER	5860538 5910180	11553	-0.013	-0.3275	No
103	EPO	940180	11631	-0.013	-0.3313	No
104	KCNK7	4230576	11684	-0.014	-0.3338	No
105	MT4	4780338	11751	-0.014	-0.3370	No
106	DLGAP4	4570672 5690161	11785	-0.014	-0.3385	No
107	MACF1	1340132 2370176 2900750 6590364	11879	-0.015	-0.3431	No
108	NEUROD2	5290097	11907	-0.015	-0.3442	No
109	FLNC	2360048 5050270	11930	-0.015	-0.3450	No
110	SMTN	670563 1190438	12004	-0.016	-0.3486	No
111	LGP2	4480338	12136	-0.017	-0.3553	No
112	KLF12	1660095 4810288 5340546 6520286	12491	-0.020	-0.3740	No
113	HOXA3	3610632 6020358	12594	-0.021	-0.3790	No
114	BCL6B	60047	12596	-0.021	-0.3785	No
115	H2AFY	4730750	13127	-0.027	-0.4066	No
116	INPP4A	510215 1090541 4850093 6100519	13170	-0.027	-0.4082	No
117	TGFB1I1	2060288 6550450	13215	-0.028	-0.4099	No
118	LRCH4	5220279 6510026	13424	-0.031	-0.4204	No
119	ABCG4	3440458	13519	-0.032	-0.4247	No
120	HOXB2	6450592	13720	-0.036	-0.4346	No
121	PKP3	3710048	13780	-0.037	-0.4369	No
122	LDLR	5670386	13802	-0.037	-0.4371	No
123	ATE1	290491 6940722	13849	-0.038	-0.4387	No
124	PLCB3	4670402	13869	-0.038	-0.4387	No
125	SYTL2	580097 5390576 6770603	14001	-0.041	-0.4448	No
126	NRGN	4280433	14020	-0.041	-0.4447	No
127	A2BP1	2370390 4590593 5550014	14204	-0.046	-0.4535	No
128	LPHN1	1400113 3130301	14414	-0.051	-0.4636	No
129	NR1D1	2360471 770746 6590204	14471	-0.053	-0.4653	No
130	IMPDH2	5220138	14487	-0.053	-0.4647	No
131	TBCC	4810021	14542	-0.055	-0.4663	No
132	MAP1A	4920576	14569	-0.056	-0.4663	No
133	RPS10	4560673	14617	-0.058	-0.4674	No
134	SLCO3A1	1050408 2370156 6110072	14744	-0.061	-0.4727	No
135	DDR1	2060044 5220180	14951	-0.069	-0.4821	No
136	PDGFB	3060440 6370008	14969	-0.070	-0.4813	No
137	TCF1	5390022	15045	-0.073	-0.4835	No
138	PVRL1	2570167 5220519 5890500 3190309	15105	-0.076	-0.4847	No
139	LBX1	1300164 4060204	15122	-0.077	-0.4837	No
140	CLSTN3	2350685	15163	-0.079	-0.4839	No
141	AP1G2	780458 2690068	15203	-0.081	-0.4839	No
142	SYNPO2L	5390719	15320	-0.088	-0.4880	No
143	ITPR3	4010632	15594	-0.105	-0.5002	No
144	RAB10	2360008 5890020	15646	-0.108	-0.5002	No
145	SPI1	1410397	15838	-0.125	-0.5074	No
146	DPYSL2	2100427 3130112 5700324	15925	-0.133	-0.5087	No
147	TYRO3	3130193	16230	-0.166	-0.5210	No
148	STAT6	1190010 5720019	16427	-0.191	-0.5269	No
149	CLIC1	110600	16455	-0.194	-0.5234	No
150	ARHGDIB	4730433	16528	-0.204	-0.5222	No
151	PEX16	4560044	16705	-0.229	-0.5260	No
152	FOXP4	6290022	16742	-0.235	-0.5220	No
153	DCTN1	1450056 6590022	16944	-0.265	-0.5263	No
154	MRPS18B	5570086	17340	-0.340	-0.5391	No
155	GRWD1	6350528	17573	-0.387	-0.5419	Yes
156	CDC42EP4	4150338	17605	-0.397	-0.5336	Yes
157	MYL6	60563 6100152	17688	-0.423	-0.5274	Yes
158	MTMR3	1050014 4920180	17763	-0.450	-0.5201	Yes
159	RHEBL1	2810576	17796	-0.460	-0.5103	Yes
160	CEBPB	2970019	17856	-0.485	-0.5013	Yes
161	ARFIP2	1850301 4670180	17865	-0.489	-0.4894	Yes
162	RHOG	6760575	17932	-0.516	-0.4800	Yes
163	PTK2B	4730411	18025	-0.567	-0.4707	Yes
164	FXC1	3710053 4060575	18043	-0.580	-0.4570	Yes
165	HSPG2	2510687 6220750	18163	-0.669	-0.4466	Yes
166	DLK1	1240138	18381	-0.977	-0.4338	Yes
167	SSBP2	2260725 2900400 4730711	18396	-1.002	-0.4093	Yes
168	IMMT	870450 4280438	18452	-1.111	-0.3844	Yes
169	PDXP	5050204 460273 6040102	18470	-1.176	-0.3557	Yes
170	NDRG2	450403	18512	-1.446	-0.3215	Yes
171	DTX1	5900372	18514	-1.475	-0.2844	Yes
172	DNMT3B	2320138 4070059	18522	-1.518	-0.2466	Yes
173	CORO1A	3140609 3190020 3190037	18548	-1.660	-0.2062	Yes
174	ETV5	110017	18562	-1.975	-0.1571	Yes
175	GNAS	630441 1850373 4050152	18597	-2.879	-0.0865	Yes
176	RHOA	580142 5900131 5340450	18605	-3.476	0.0006	Yes