Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$PEA3_Q6 |
Enrichment Score (ES) | -0.56216383 |
Normalized Enrichment Score (NES) | -1.4340492 |
Nominal p-value | 0.008183306 |
FDR q-value | 0.70893866 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PRKACB | 4210170 | 143 | 1.046 | 0.0236 | No | ||
2 | INPPL1 | 110717 3120164 | 710 | 0.509 | 0.0082 | No | ||
3 | TRIM8 | 6130441 | 733 | 0.496 | 0.0219 | No | ||
4 | GTF2H1 | 2570746 2650148 | 1029 | 0.381 | 0.0174 | No | ||
5 | CD84 | 1780168 | 1190 | 0.337 | 0.0188 | No | ||
6 | PTPRC | 130402 5290148 | 1289 | 0.312 | 0.0228 | No | ||
7 | LRMP | 6290193 | 1317 | 0.303 | 0.0304 | No | ||
8 | TMEM24 | 5860039 | 1346 | 0.295 | 0.0378 | No | ||
9 | GATA3 | 6130068 | 1562 | 0.243 | 0.0334 | No | ||
10 | FLI1 | 3990142 | 1617 | 0.231 | 0.0374 | No | ||
11 | NT5C2 | 4280735 4670528 | 1622 | 0.231 | 0.0441 | No | ||
12 | SPATA6 | 4590373 | 1651 | 0.225 | 0.0493 | No | ||
13 | SEC24C | 6980707 | 1695 | 0.218 | 0.0535 | No | ||
14 | DCLRE1C | 1450041 2360091 3290671 3390739 | 1794 | 0.200 | 0.0542 | No | ||
15 | ARF3 | 3710446 | 2002 | 0.168 | 0.0481 | No | ||
16 | CDC14A | 4050132 | 2011 | 0.167 | 0.0526 | No | ||
17 | MR1 | 3850037 | 2043 | 0.161 | 0.0558 | No | ||
18 | TRIM33 | 580619 2230280 3990433 6200747 | 2093 | 0.154 | 0.0577 | No | ||
19 | EXTL2 | 5050433 | 2178 | 0.141 | 0.0574 | No | ||
20 | MARK2 | 7210608 | 2387 | 0.117 | 0.0497 | No | ||
21 | TNFRSF19L | 1170168 1190358 5670270 | 2428 | 0.113 | 0.0509 | No | ||
22 | LZTS2 | 2260440 | 2435 | 0.113 | 0.0540 | No | ||
23 | PUM1 | 6130500 | 2470 | 0.109 | 0.0554 | No | ||
24 | VDAC2 | 7000215 | 2506 | 0.105 | 0.0566 | No | ||
25 | ZDHHC5 | 1690711 | 2523 | 0.104 | 0.0589 | No | ||
26 | SLC35C1 | 4540154 | 2525 | 0.104 | 0.0619 | No | ||
27 | ABLIM1 | 580170 3710338 6520504 | 2817 | 0.081 | 0.0486 | No | ||
28 | ITPR2 | 5360128 | 2911 | 0.074 | 0.0458 | No | ||
29 | GFI1 | 730180 | 2968 | 0.070 | 0.0448 | No | ||
30 | TCEB3 | 5890156 | 3016 | 0.066 | 0.0443 | No | ||
31 | IRAK4 | 5390156 6130594 | 3062 | 0.064 | 0.0438 | No | ||
32 | FEN1 | 1770541 | 3133 | 0.059 | 0.0417 | No | ||
33 | SNCG | 3120725 | 3171 | 0.057 | 0.0414 | No | ||
34 | CD69 | 380167 4730088 | 3256 | 0.052 | 0.0385 | No | ||
35 | CTBP2 | 430309 3710079 | 3326 | 0.049 | 0.0362 | No | ||
36 | KCNAB2 | 4850315 | 3398 | 0.046 | 0.0337 | No | ||
37 | LAMC1 | 4730025 | 3413 | 0.045 | 0.0343 | No | ||
38 | CAMK1D | 1660100 2350309 | 3475 | 0.043 | 0.0323 | No | ||
39 | RIN1 | 510593 | 3517 | 0.041 | 0.0313 | No | ||
40 | PICALM | 1940280 | 3524 | 0.041 | 0.0322 | No | ||
41 | PAFAH2 | 3140451 5720593 6510014 | 3533 | 0.040 | 0.0330 | No | ||
42 | ANK3 | 1500161 2900435 4210154 6400100 | 3544 | 0.040 | 0.0337 | No | ||
43 | CBL | 6380068 | 3650 | 0.036 | 0.0291 | No | ||
44 | RAB39 | 430524 | 3822 | 0.031 | 0.0207 | No | ||
45 | SV2A | 1450039 5570685 | 4095 | 0.024 | 0.0067 | No | ||
46 | TIAL1 | 4150048 6510605 | 4834 | 0.014 | -0.0328 | No | ||
47 | HIPK1 | 110193 | 4952 | 0.013 | -0.0388 | No | ||
48 | SLC41A1 | 1230528 | 4953 | 0.013 | -0.0384 | No | ||
49 | CAPZA1 | 3140390 | 4969 | 0.013 | -0.0388 | No | ||
50 | GRIN2B | 3800333 | 4998 | 0.013 | -0.0400 | No | ||
51 | FUT11 | 6040692 | 5151 | 0.011 | -0.0479 | No | ||
52 | SPRR4 | 5720273 | 5417 | 0.010 | -0.0619 | No | ||
53 | ELK4 | 460494 940369 4480136 | 5571 | 0.009 | -0.0700 | No | ||
54 | CMAS | 2190129 | 5759 | 0.008 | -0.0799 | No | ||
55 | LIN28 | 6590672 | 5827 | 0.007 | -0.0833 | No | ||
56 | XCL1 | 3800504 | 5872 | 0.007 | -0.0855 | No | ||
57 | RNASEL | 2340133 | 5931 | 0.007 | -0.0884 | No | ||
58 | BDNF | 2940128 3520368 | 5977 | 0.007 | -0.0906 | No | ||
59 | CACNA1E | 840253 | 7522 | 0.001 | -0.1743 | No | ||
60 | NCAM1 | 3140026 | 7612 | 0.001 | -0.1791 | No | ||
61 | AKT3 | 1580270 3290278 | 7974 | -0.000 | -0.1986 | No | ||
62 | GPA33 | 2650044 | 8073 | -0.001 | -0.2039 | No | ||
63 | TAF5 | 3450288 5890193 6860435 | 8420 | -0.001 | -0.2226 | No | ||
64 | MMP7 | 1780497 | 8489 | -0.002 | -0.2262 | No | ||
65 | GAB2 | 1410280 2340520 4280040 | 8525 | -0.002 | -0.2281 | No | ||
66 | EHF | 4560088 | 8640 | -0.002 | -0.2342 | No | ||
67 | ANKRD1 | 4850685 | 8876 | -0.003 | -0.2468 | No | ||
68 | NCF2 | 540129 2370441 2650133 | 8921 | -0.003 | -0.2491 | No | ||
69 | CPNE8 | 7040039 | 9458 | -0.004 | -0.2780 | No | ||
70 | XPNPEP1 | 2640750 3850315 6200242 | 9677 | -0.005 | -0.2897 | No | ||
71 | IPO7 | 2190746 | 10257 | -0.007 | -0.3209 | No | ||
72 | FUCA1 | 610075 | 10504 | -0.008 | -0.3339 | No | ||
73 | PDGFD | 60438 | 10508 | -0.008 | -0.3339 | No | ||
74 | PAX6 | 1190025 | 10706 | -0.009 | -0.3443 | No | ||
75 | FGF23 | 510746 | 10764 | -0.009 | -0.3471 | No | ||
76 | KAZALD1 | 380603 | 11091 | -0.011 | -0.3644 | No | ||
77 | ADAMTS4 | 430435 | 11287 | -0.011 | -0.3747 | No | ||
78 | IL18 | 6180039 | 11367 | -0.012 | -0.3786 | No | ||
79 | PGM2L1 | 2350035 | 11409 | -0.012 | -0.3804 | No | ||
80 | VPS11 | 1090048 6040372 | 11413 | -0.012 | -0.3802 | No | ||
81 | LALBA | 6940685 | 11447 | -0.012 | -0.3817 | No | ||
82 | PBXIP1 | 70131 | 11844 | -0.015 | -0.4027 | No | ||
83 | RUNX3 | 3800546 | 12583 | -0.021 | -0.4421 | No | ||
84 | MARK1 | 450484 | 12605 | -0.021 | -0.4426 | No | ||
85 | IVL | 4560500 | 12717 | -0.022 | -0.4479 | No | ||
86 | ST7L | 840735 2360576 | 12829 | -0.023 | -0.4533 | No | ||
87 | HHEX | 2340575 | 12859 | -0.023 | -0.4541 | No | ||
88 | PRDX6 | 4920397 6380601 | 12934 | -0.024 | -0.4574 | No | ||
89 | EPHA2 | 5890056 | 13132 | -0.027 | -0.4673 | No | ||
90 | CUGBP1 | 450292 510022 7050176 7050215 | 13251 | -0.028 | -0.4728 | No | ||
91 | DMBT1 | 7050270 | 13394 | -0.030 | -0.4796 | No | ||
92 | RPS3 | 1570017 2370170 | 13523 | -0.032 | -0.4856 | No | ||
93 | PLCB3 | 4670402 | 13869 | -0.038 | -0.5031 | No | ||
94 | SLC30A7 | 2230463 | 13894 | -0.039 | -0.5033 | No | ||
95 | NRGN | 4280433 | 14020 | -0.041 | -0.5088 | No | ||
96 | GPR120 | 2350398 | 14161 | -0.045 | -0.5150 | No | ||
97 | CD3E | 3800056 | 14295 | -0.048 | -0.5208 | No | ||
98 | CTSS | 1740056 | 14673 | -0.059 | -0.5395 | No | ||
99 | SELP | 6040193 | 14793 | -0.064 | -0.5440 | No | ||
100 | ELAVL4 | 50735 3360086 5220167 | 14810 | -0.064 | -0.5429 | No | ||
101 | SORL1 | 630204 | 14896 | -0.067 | -0.5455 | No | ||
102 | MMRN2 | 1740047 | 14946 | -0.069 | -0.5461 | No | ||
103 | CENTD2 | 60408 2510156 6100494 | 14974 | -0.070 | -0.5455 | No | ||
104 | BCL2L14 | 2940279 | 15194 | -0.081 | -0.5549 | No | ||
105 | SLC26A9 | 3440722 5340088 7510093 | 15204 | -0.081 | -0.5529 | No | ||
106 | LTBR | 2450341 | 15229 | -0.083 | -0.5518 | No | ||
107 | NUMA1 | 6520576 | 15397 | -0.092 | -0.5580 | No | ||
108 | WASF2 | 4850592 | 15474 | -0.098 | -0.5592 | Yes | ||
109 | ETV3 | 5360487 | 15518 | -0.101 | -0.5585 | Yes | ||
110 | ZRANB1 | 510373 4540278 | 15533 | -0.102 | -0.5562 | Yes | ||
111 | ITPKB | 2900195 7100039 | 15641 | -0.108 | -0.5588 | Yes | ||
112 | CYR61 | 1240408 5290026 4120452 6550008 | 15657 | -0.109 | -0.5563 | Yes | ||
113 | SIPA1 | 5220687 | 15726 | -0.115 | -0.5566 | Yes | ||
114 | LRFN4 | 5670368 | 15796 | -0.121 | -0.5567 | Yes | ||
115 | SPI1 | 1410397 | 15838 | -0.125 | -0.5551 | Yes | ||
116 | KCNQ1 | 1580050 6860441 | 15863 | -0.128 | -0.5526 | Yes | ||
117 | DPP3 | 2680725 3780670 | 15926 | -0.133 | -0.5520 | Yes | ||
118 | SYTL1 | 510487 | 15953 | -0.136 | -0.5493 | Yes | ||
119 | PIK4CB | 510450 1780452 | 16076 | -0.149 | -0.5514 | Yes | ||
120 | LAG3 | 6860112 | 16116 | -0.152 | -0.5490 | Yes | ||
121 | IL18BP | 3450128 | 16244 | -0.167 | -0.5509 | Yes | ||
122 | LCK | 3360142 | 16351 | -0.181 | -0.5512 | Yes | ||
123 | ADRBK1 | 1340333 | 16367 | -0.183 | -0.5465 | Yes | ||
124 | ARHGDIB | 4730433 | 16528 | -0.204 | -0.5491 | Yes | ||
125 | EPC1 | 1570050 5290095 6900193 | 16538 | -0.205 | -0.5434 | Yes | ||
126 | RPS6KA4 | 2190524 | 16579 | -0.211 | -0.5392 | Yes | ||
127 | VCAM1 | 2900450 | 16667 | -0.222 | -0.5373 | Yes | ||
128 | CD53 | 5550162 | 16723 | -0.232 | -0.5333 | Yes | ||
129 | ESRRA | 6550242 | 16820 | -0.247 | -0.5311 | Yes | ||
130 | MAP4K2 | 4200037 | 16873 | -0.254 | -0.5263 | Yes | ||
131 | CAP1 | 2650278 | 16961 | -0.267 | -0.5230 | Yes | ||
132 | PRF1 | 6660309 | 17060 | -0.285 | -0.5198 | Yes | ||
133 | SLC2A3 | 1990377 | 17077 | -0.287 | -0.5120 | Yes | ||
134 | NDUFS2 | 4850020 6200402 | 17105 | -0.292 | -0.5048 | Yes | ||
135 | SRRM1 | 6110025 | 17117 | -0.295 | -0.4965 | Yes | ||
136 | PTPN6 | 4230128 | 17329 | -0.337 | -0.4978 | Yes | ||
137 | LPXN | 2360142 | 17446 | -0.359 | -0.4934 | Yes | ||
138 | ZNF289 | 3610390 3870711 3940138 5340373 | 17602 | -0.396 | -0.4899 | Yes | ||
139 | BLNK | 70288 6590092 | 17777 | -0.456 | -0.4857 | Yes | ||
140 | FCGR3A | 3840184 | 17799 | -0.462 | -0.4730 | Yes | ||
141 | GPD1 | 2480095 | 17833 | -0.474 | -0.4605 | Yes | ||
142 | ELOVL1 | 2450019 4760138 5340685 | 17838 | -0.478 | -0.4464 | Yes | ||
143 | RHOG | 6760575 | 17932 | -0.516 | -0.4360 | Yes | ||
144 | SELL | 1190500 | 17938 | -0.519 | -0.4207 | Yes | ||
145 | TYSND1 | 2940273 | 17968 | -0.532 | -0.4063 | Yes | ||
146 | UNC93B1 | 430152 | 18016 | -0.563 | -0.3920 | Yes | ||
147 | MAPKAPK2 | 2850500 | 18097 | -0.619 | -0.3777 | Yes | ||
148 | TNNI2 | 5910739 | 18129 | -0.638 | -0.3603 | Yes | ||
149 | TCIRG1 | 4590524 5910079 6900619 | 18131 | -0.642 | -0.3411 | Yes | ||
150 | POLD4 | 2320082 | 18150 | -0.660 | -0.3223 | Yes | ||
151 | POU2AF1 | 5690242 | 18189 | -0.694 | -0.3035 | Yes | ||
152 | CDKN2C | 5050750 5130148 | 18240 | -0.763 | -0.2834 | Yes | ||
153 | CTSW | 360368 | 18309 | -0.884 | -0.2605 | Yes | ||
154 | IL2RA | 6620450 | 18311 | -0.888 | -0.2340 | Yes | ||
155 | CD5 | 6590338 | 18345 | -0.931 | -0.2078 | Yes | ||
156 | SLAMF9 | 3710300 | 18479 | -1.201 | -0.1790 | Yes | ||
157 | DGKZ | 3460041 6400129 | 18483 | -1.227 | -0.1424 | Yes | ||
158 | SSBP3 | 870717 1050377 7040551 | 18524 | -1.522 | -0.0989 | Yes | ||
159 | MFN2 | 2260195 6100164 | 18604 | -3.462 | 0.0007 | Yes |