Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$E47_02 |
Enrichment Score (ES) | -0.4981863 |
Normalized Enrichment Score (NES) | -1.2687824 |
Nominal p-value | 0.03709428 |
FDR q-value | 0.92081136 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TRAM1 | 2340441 6620592 | 452 | 0.652 | 0.0045 | No | ||
2 | LUC7L | 6040156 6110411 | 528 | 0.608 | 0.0275 | No | ||
3 | EHD4 | 5890278 | 706 | 0.511 | 0.0407 | No | ||
4 | EGLN1 | 2480180 3120253 6110195 | 724 | 0.502 | 0.0621 | No | ||
5 | TSGA14 | 6660465 | 969 | 0.408 | 0.0670 | No | ||
6 | IDE | 670746 | 1006 | 0.391 | 0.0825 | No | ||
7 | NDUFS4 | 510142 1240148 4760253 | 1089 | 0.363 | 0.0942 | No | ||
8 | BCL2L1 | 1580452 4200152 5420484 | 1257 | 0.321 | 0.0995 | No | ||
9 | NR2F6 | 1340239 5670239 60338 4280088 | 1570 | 0.241 | 0.0933 | No | ||
10 | SLC7A11 | 2850138 | 1849 | 0.190 | 0.0866 | No | ||
11 | BMF | 610102 | 1859 | 0.188 | 0.0945 | No | ||
12 | HMGN2 | 3140091 | 1972 | 0.172 | 0.0961 | No | ||
13 | PSMD3 | 1400647 | 2174 | 0.142 | 0.0915 | No | ||
14 | LYL1 | 2900242 | 2213 | 0.136 | 0.0955 | No | ||
15 | ART1 | 450288 4570292 | 2437 | 0.112 | 0.0884 | No | ||
16 | CHRNB1 | 1190671 | 2664 | 0.092 | 0.0803 | No | ||
17 | AMPH | 2260338 3140576 | 2755 | 0.085 | 0.0792 | No | ||
18 | TRERF1 | 6370017 6940138 | 2775 | 0.084 | 0.0819 | No | ||
19 | STRN3 | 1450093 6200685 | 2806 | 0.081 | 0.0839 | No | ||
20 | KCNN2 | 990025 3520524 | 2906 | 0.074 | 0.0818 | No | ||
21 | STK3 | 7100427 | 2932 | 0.072 | 0.0837 | No | ||
22 | HIVEP3 | 3990551 | 2984 | 0.069 | 0.0840 | No | ||
23 | THRA | 6770341 110164 1990600 | 3137 | 0.059 | 0.0784 | No | ||
24 | GALR3 | 4850113 | 3182 | 0.056 | 0.0785 | No | ||
25 | USP54 | 3060079 | 3239 | 0.053 | 0.0778 | No | ||
26 | RWDD2 | 1660079 | 3306 | 0.050 | 0.0764 | No | ||
27 | UNC5B | 2370279 | 3319 | 0.049 | 0.0780 | No | ||
28 | SHOX2 | 3190438 6450059 | 3346 | 0.048 | 0.0787 | No | ||
29 | ERG | 50154 1770739 | 3416 | 0.045 | 0.0770 | No | ||
30 | BAZ2A | 730184 | 3525 | 0.041 | 0.0729 | No | ||
31 | ADAM12 | 3390132 4070347 | 3596 | 0.038 | 0.0708 | No | ||
32 | TRIM23 | 580168 6510672 | 3607 | 0.038 | 0.0720 | No | ||
33 | MKL1 | 6840161 | 3623 | 0.037 | 0.0728 | No | ||
34 | PODXL | 130717 | 3635 | 0.037 | 0.0738 | No | ||
35 | ASXL2 | 130670 | 3675 | 0.035 | 0.0733 | No | ||
36 | SCN5A | 4070017 | 3798 | 0.032 | 0.0681 | No | ||
37 | SEMA4G | 5890026 | 3825 | 0.031 | 0.0680 | No | ||
38 | SLITRK3 | 5910041 | 3975 | 0.027 | 0.0612 | No | ||
39 | SOX12 | 1780037 | 4005 | 0.026 | 0.0608 | No | ||
40 | HOXA7 | 5910152 | 4020 | 0.026 | 0.0612 | No | ||
41 | CPNE1 | 3440131 | 4035 | 0.026 | 0.0616 | No | ||
42 | CDH7 | 6620722 | 4037 | 0.026 | 0.0626 | No | ||
43 | WNT10B | 510050 | 4386 | 0.020 | 0.0446 | No | ||
44 | JMJD1C | 940575 2120025 | 4403 | 0.019 | 0.0446 | No | ||
45 | GATM | 380671 | 4410 | 0.019 | 0.0452 | No | ||
46 | TAL1 | 7040239 | 4485 | 0.018 | 0.0420 | No | ||
47 | RHOBTB1 | 1410010 | 4528 | 0.018 | 0.0405 | No | ||
48 | HAPLN2 | 2900647 | 4579 | 0.017 | 0.0385 | No | ||
49 | PCM1 | 1940070 3940707 | 4680 | 0.016 | 0.0338 | No | ||
50 | DUSP9 | 630605 | 4881 | 0.014 | 0.0236 | No | ||
51 | PCDHA1 | 940026 540484 | 4928 | 0.013 | 0.0217 | No | ||
52 | TEAD2 | 6450079 | 4929 | 0.013 | 0.0222 | No | ||
53 | RRM2B | 1690025 1690465 4010400 | 4967 | 0.013 | 0.0208 | No | ||
54 | FUT8 | 1340068 2340056 | 5196 | 0.011 | 0.0089 | No | ||
55 | DSCAM | 1780050 2450731 2810438 | 5269 | 0.011 | 0.0055 | No | ||
56 | FGD4 | 520168 870411 2640253 6550338 6650364 | 5303 | 0.010 | 0.0042 | No | ||
57 | KLHL13 | 6590731 | 5335 | 0.010 | 0.0030 | No | ||
58 | SDPR | 3360292 | 5454 | 0.009 | -0.0030 | No | ||
59 | PFTK1 | 1780181 | 5521 | 0.009 | -0.0062 | No | ||
60 | DSCAML1 | 1850403 5550079 | 5653 | 0.008 | -0.0130 | No | ||
61 | NPTX2 | 70021 | 5764 | 0.008 | -0.0186 | No | ||
62 | PURA | 3870156 | 5916 | 0.007 | -0.0265 | No | ||
63 | PDE4B | 4480121 | 5945 | 0.007 | -0.0277 | No | ||
64 | TCF2 | 870338 5050632 | 5950 | 0.007 | -0.0276 | No | ||
65 | GRIA1 | 1340152 3780750 4920440 | 5971 | 0.007 | -0.0284 | No | ||
66 | GFAP | 2060092 | 6098 | 0.006 | -0.0350 | No | ||
67 | IRX4 | 1980102 | 6110 | 0.006 | -0.0353 | No | ||
68 | BMX | 50136 2940242 4540059 | 6352 | 0.005 | -0.0482 | No | ||
69 | MYC | 380541 4670170 | 6391 | 0.005 | -0.0500 | No | ||
70 | DOC2B | 2190021 2850142 | 6479 | 0.004 | -0.0545 | No | ||
71 | PRKCQ | 2260170 3870193 | 6705 | 0.004 | -0.0666 | No | ||
72 | SLC9A7 | 5360301 | 7150 | 0.002 | -0.0905 | No | ||
73 | LRRN3 | 1450133 | 7281 | 0.002 | -0.0975 | No | ||
74 | FGF11 | 840292 | 7297 | 0.002 | -0.0983 | No | ||
75 | MMP16 | 2680139 | 7380 | 0.001 | -0.1026 | No | ||
76 | ASB5 | 2760575 | 7509 | 0.001 | -0.1095 | No | ||
77 | NOV | 2850746 | 7733 | 0.000 | -0.1216 | No | ||
78 | SERPINI2 | 1570427 | 7874 | 0.000 | -0.1292 | No | ||
79 | EDG1 | 4200619 | 7994 | -0.000 | -0.1356 | No | ||
80 | CHRM1 | 4280619 | 8046 | -0.000 | -0.1384 | No | ||
81 | NGFR | 3140102 | 8334 | -0.001 | -0.1539 | No | ||
82 | FOXI1 | 3710095 6620195 | 8372 | -0.001 | -0.1558 | No | ||
83 | DDAH1 | 6400750 | 8597 | -0.002 | -0.1679 | No | ||
84 | BTBD3 | 1980041 2510577 3190053 4200746 | 8628 | -0.002 | -0.1694 | No | ||
85 | PGM3 | 2570465 | 8639 | -0.002 | -0.1699 | No | ||
86 | LRRN1 | 3290154 | 8811 | -0.003 | -0.1790 | No | ||
87 | KCNA4 | 2320706 | 8857 | -0.003 | -0.1813 | No | ||
88 | ARL4A | 6290091 | 8931 | -0.003 | -0.1852 | No | ||
89 | AKT2 | 3850541 3870519 | 8973 | -0.003 | -0.1873 | No | ||
90 | JPH3 | 780397 | 9272 | -0.004 | -0.2032 | No | ||
91 | ACCN1 | 2060139 2190541 | 9403 | -0.004 | -0.2101 | No | ||
92 | PCDHA10 | 3830725 | 9646 | -0.005 | -0.2230 | No | ||
93 | SNCAIP | 4010551 | 9847 | -0.006 | -0.2336 | No | ||
94 | BTBD11 | 6650154 | 9877 | -0.006 | -0.2349 | No | ||
95 | GABRE | 4780020 | 9880 | -0.006 | -0.2348 | No | ||
96 | HDAC9 | 1990010 2260133 | 10013 | -0.006 | -0.2416 | No | ||
97 | KLK1 | 6040369 | 10055 | -0.006 | -0.2436 | No | ||
98 | TTN | 2320161 4670056 6550026 | 10134 | -0.007 | -0.2475 | No | ||
99 | ATOH7 | 5550121 | 10460 | -0.008 | -0.2648 | No | ||
100 | NPAS2 | 770670 | 10812 | -0.009 | -0.2834 | No | ||
101 | FOXA1 | 3710609 | 10870 | -0.009 | -0.2861 | No | ||
102 | BNC2 | 4810603 | 10884 | -0.010 | -0.2863 | No | ||
103 | HSPB3 | 460129 | 10994 | -0.010 | -0.2918 | No | ||
104 | MESDC1 | 2030019 | 11048 | -0.010 | -0.2942 | No | ||
105 | ANXA8 | 4780022 | 11259 | -0.011 | -0.3051 | No | ||
106 | MEF2C | 670025 780338 | 11283 | -0.011 | -0.3058 | No | ||
107 | ABR | 610079 1170609 3610195 5670050 | 11310 | -0.012 | -0.3067 | No | ||
108 | DRD3 | 4780402 | 11568 | -0.013 | -0.3201 | No | ||
109 | GJA4 | 6380452 | 11579 | -0.013 | -0.3201 | No | ||
110 | OFCC1 | 2060392 | 11600 | -0.013 | -0.3206 | No | ||
111 | KLHL1 | 6350021 | 11655 | -0.013 | -0.3229 | No | ||
112 | CNTN6 | 2630711 | 11818 | -0.014 | -0.3310 | No | ||
113 | ERBB3 | 5890372 | 11878 | -0.015 | -0.3336 | No | ||
114 | PLEKHB1 | 3120039 4050270 540546 870463 | 12223 | -0.017 | -0.3515 | No | ||
115 | CALB1 | 460070 | 12242 | -0.018 | -0.3516 | No | ||
116 | DMD | 1740041 3990332 | 12328 | -0.018 | -0.3554 | No | ||
117 | AP4S1 | 4730292 | 12481 | -0.020 | -0.3628 | No | ||
118 | RIMS2 | 670725 | 12541 | -0.020 | -0.3651 | No | ||
119 | ELAVL2 | 360181 | 12702 | -0.022 | -0.3728 | No | ||
120 | UBXD3 | 5050193 | 12798 | -0.023 | -0.3770 | No | ||
121 | BZW2 | 940079 | 12976 | -0.025 | -0.3855 | No | ||
122 | HSD3B7 | 1410129 | 13018 | -0.025 | -0.3866 | No | ||
123 | PCSK4 | 130687 670711 3170075 6400411 | 13040 | -0.026 | -0.3866 | No | ||
124 | PCDHA6 | 780333 2370280 | 13084 | -0.026 | -0.3877 | No | ||
125 | CUGBP1 | 450292 510022 7050176 7050215 | 13251 | -0.028 | -0.3955 | No | ||
126 | NOL4 | 5050446 5360519 | 13315 | -0.029 | -0.3976 | No | ||
127 | MYOCD | 2650064 3440403 6220121 | 13366 | -0.030 | -0.3990 | No | ||
128 | MEF2D | 5690576 | 13409 | -0.031 | -0.3999 | No | ||
129 | POU3F2 | 6620484 | 13425 | -0.031 | -0.3993 | No | ||
130 | MLLT6 | 3870168 | 13426 | -0.031 | -0.3980 | No | ||
131 | SNAP25 | 360520 | 13442 | -0.031 | -0.3974 | No | ||
132 | CEL | 2640278 | 13653 | -0.034 | -0.4073 | No | ||
133 | CASKIN2 | 2030113 | 13732 | -0.036 | -0.4099 | No | ||
134 | DDAH2 | 4480551 | 13859 | -0.038 | -0.4150 | No | ||
135 | SYTL2 | 580097 5390576 6770603 | 14001 | -0.041 | -0.4208 | No | ||
136 | WDR6 | 7050154 | 14146 | -0.045 | -0.4267 | No | ||
137 | A2BP1 | 2370390 4590593 5550014 | 14204 | -0.046 | -0.4277 | No | ||
138 | BRUNOL4 | 4490452 5080451 | 14228 | -0.046 | -0.4269 | No | ||
139 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14267 | -0.047 | -0.4269 | No | ||
140 | MAPK12 | 450022 1340717 7050484 | 14503 | -0.054 | -0.4372 | No | ||
141 | CPB1 | 290600 | 14641 | -0.058 | -0.4421 | No | ||
142 | FGF13 | 630575 1570440 5360121 | 14771 | -0.063 | -0.4463 | No | ||
143 | ALX3 | 50497 | 14962 | -0.070 | -0.4535 | No | ||
144 | ACCN4 | 6380551 | 15043 | -0.073 | -0.4545 | No | ||
145 | TPM2 | 520735 3870390 | 15138 | -0.078 | -0.4562 | No | ||
146 | NUMBL | 6130360 6200333 | 15240 | -0.083 | -0.4579 | No | ||
147 | PRELP | 5900390 | 15442 | -0.096 | -0.4645 | No | ||
148 | CRSP7 | 4230408 | 16055 | -0.147 | -0.4912 | Yes | ||
149 | BCL9 | 7100112 | 16185 | -0.161 | -0.4910 | Yes | ||
150 | HDAC3 | 4060072 | 16189 | -0.161 | -0.4840 | Yes | ||
151 | MYO18A | 1230333 | 16350 | -0.181 | -0.4847 | Yes | ||
152 | STC2 | 4920601 | 16393 | -0.187 | -0.4786 | Yes | ||
153 | LMO2 | 5360450 | 16607 | -0.215 | -0.4806 | Yes | ||
154 | DULLARD | 130180 | 16636 | -0.219 | -0.4724 | Yes | ||
155 | ARMCX2 | 2320167 | 16644 | -0.219 | -0.4630 | Yes | ||
156 | ARID5A | 2450133 | 16789 | -0.242 | -0.4601 | Yes | ||
157 | PARD6A | 4120170 | 17016 | -0.276 | -0.4600 | Yes | ||
158 | CUEDC1 | 1660463 | 17025 | -0.278 | -0.4481 | Yes | ||
159 | MGAT1 | 2450377 | 17363 | -0.344 | -0.4510 | Yes | ||
160 | SASH1 | 4070270 | 17444 | -0.358 | -0.4394 | Yes | ||
161 | IRF1 | 2340152 3450592 6290121 6980577 | 17521 | -0.374 | -0.4269 | Yes | ||
162 | TRIB2 | 4120605 | 17634 | -0.408 | -0.4148 | Yes | ||
163 | RAB33A | 6590195 | 17666 | -0.417 | -0.3979 | Yes | ||
164 | TNFSF13 | 2650170 | 17840 | -0.479 | -0.3860 | Yes | ||
165 | GNA12 | 1230301 | 17879 | -0.495 | -0.3660 | Yes | ||
166 | DGKA | 5720152 5890328 | 18038 | -0.577 | -0.3489 | Yes | ||
167 | POU2AF1 | 5690242 | 18189 | -0.694 | -0.3261 | Yes | ||
168 | AIG1 | 2450091 | 18259 | -0.795 | -0.2945 | Yes | ||
169 | TPI1 | 1500215 2100154 | 18279 | -0.825 | -0.2588 | Yes | ||
170 | PADI4 | 1740075 4810441 | 18412 | -1.039 | -0.2197 | Yes | ||
171 | HES6 | 540411 6550504 | 18520 | -1.504 | -0.1586 | Yes | ||
172 | NCDN | 50040 1980739 3520603 | 18539 | -1.599 | -0.0884 | Yes | ||
173 | EPHB6 | 5860128 | 18572 | -2.078 | 0.0024 | Yes |