Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$E12_Q6 |
Enrichment Score (ES) | -0.5158868 |
Normalized Enrichment Score (NES) | -1.3162124 |
Nominal p-value | 0.029032258 |
FDR q-value | 0.8650776 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TPM3 | 670600 3170296 5670167 6650471 | 2 | 4.583 | 0.1274 | No | ||
2 | MFNG | 1770242 4280348 | 342 | 0.747 | 0.1298 | No | ||
3 | RRAGC | 5910348 | 579 | 0.577 | 0.1331 | No | ||
4 | RUNX1 | 3840711 | 602 | 0.563 | 0.1475 | No | ||
5 | NEDD4L | 6380368 | 661 | 0.535 | 0.1593 | No | ||
6 | EGLN1 | 2480180 3120253 6110195 | 724 | 0.502 | 0.1699 | No | ||
7 | CFL1 | 2340735 | 1010 | 0.389 | 0.1653 | No | ||
8 | OSR1 | 1500025 | 1264 | 0.319 | 0.1604 | No | ||
9 | PLAGL2 | 1770148 | 1306 | 0.305 | 0.1667 | No | ||
10 | LRP10 | 1580128 | 1471 | 0.262 | 0.1651 | No | ||
11 | SLC23A2 | 6660722 | 1550 | 0.245 | 0.1677 | No | ||
12 | NUP88 | 2510044 6760180 | 1687 | 0.219 | 0.1664 | No | ||
13 | HMGN2 | 3140091 | 1972 | 0.172 | 0.1558 | No | ||
14 | GRB2 | 6650398 | 2342 | 0.122 | 0.1391 | No | ||
15 | LNX2 | 3130025 | 2455 | 0.111 | 0.1361 | No | ||
16 | WNT6 | 4570364 | 2497 | 0.106 | 0.1369 | No | ||
17 | SORT1 | 1850242 2320632 3870537 | 2503 | 0.106 | 0.1395 | No | ||
18 | NTRK3 | 4050687 4070167 4610026 6100484 | 2796 | 0.083 | 0.1260 | No | ||
19 | TGFB3 | 1070041 | 2869 | 0.077 | 0.1242 | No | ||
20 | PACSIN3 | 4540369 4540400 5360037 6940129 | 3071 | 0.063 | 0.1151 | No | ||
21 | EYA3 | 1580195 6510632 | 3124 | 0.060 | 0.1139 | No | ||
22 | CAMK2A | 1740333 1940112 4150292 | 3196 | 0.055 | 0.1116 | No | ||
23 | CAMK1D | 1660100 2350309 | 3475 | 0.043 | 0.0977 | No | ||
24 | RIN1 | 510593 | 3517 | 0.041 | 0.0967 | No | ||
25 | ADAM12 | 3390132 4070347 | 3596 | 0.038 | 0.0935 | No | ||
26 | TRIM23 | 580168 6510672 | 3607 | 0.038 | 0.0940 | No | ||
27 | TNFAIP1 | 6940593 | 3753 | 0.033 | 0.0871 | No | ||
28 | WDR20 | 1240373 | 3862 | 0.030 | 0.0820 | No | ||
29 | EIF2C1 | 6900551 | 3904 | 0.029 | 0.0806 | No | ||
30 | CDH5 | 5340487 | 4039 | 0.026 | 0.0741 | No | ||
31 | CNNM2 | 2650100 | 4041 | 0.026 | 0.0747 | No | ||
32 | SSH2 | 360056 | 4096 | 0.024 | 0.0725 | No | ||
33 | ASB14 | 5860427 | 4240 | 0.022 | 0.0653 | No | ||
34 | CHRDL1 | 1580037 6380204 | 4394 | 0.019 | 0.0576 | No | ||
35 | COL4A4 | 1050541 | 4520 | 0.018 | 0.0513 | No | ||
36 | ITGA6 | 3830129 | 4560 | 0.017 | 0.0496 | No | ||
37 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 4731 | 0.015 | 0.0409 | No | ||
38 | SIM1 | 1770332 | 4790 | 0.015 | 0.0381 | No | ||
39 | NTRK2 | 6220463 | 4827 | 0.014 | 0.0366 | No | ||
40 | RAB26 | 5910025 | 4848 | 0.014 | 0.0359 | No | ||
41 | PIM2 | 840136 5720692 7100577 | 4949 | 0.013 | 0.0308 | No | ||
42 | KCNN3 | 6520600 6420138 | 5093 | 0.012 | 0.0234 | No | ||
43 | SOX17 | 5270551 | 5141 | 0.011 | 0.0211 | No | ||
44 | HR | 2690095 6200300 | 5150 | 0.011 | 0.0210 | No | ||
45 | FUT8 | 1340068 2340056 | 5196 | 0.011 | 0.0189 | No | ||
46 | DSCAM | 1780050 2450731 2810438 | 5269 | 0.011 | 0.0153 | No | ||
47 | KLHL13 | 6590731 | 5335 | 0.010 | 0.0120 | No | ||
48 | RAPGEF4 | 6100563 | 5421 | 0.010 | 0.0077 | No | ||
49 | NEGR1 | 1940731 5130170 | 5509 | 0.009 | 0.0032 | No | ||
50 | WTAP | 4010176 | 5639 | 0.008 | -0.0035 | No | ||
51 | ANKRD2 | 6590427 | 5790 | 0.007 | -0.0115 | No | ||
52 | PCDH15 | 7000438 | 5906 | 0.007 | -0.0175 | No | ||
53 | TCF2 | 870338 5050632 | 5950 | 0.007 | -0.0197 | No | ||
54 | GRIA1 | 1340152 3780750 4920440 | 5971 | 0.007 | -0.0206 | No | ||
55 | UNC13B | 130735 | 5976 | 0.007 | -0.0206 | No | ||
56 | MTSS1 | 780435 2370114 | 6065 | 0.006 | -0.0252 | No | ||
57 | MYH14 | 4010017 | 6066 | 0.006 | -0.0250 | No | ||
58 | GFAP | 2060092 | 6098 | 0.006 | -0.0266 | No | ||
59 | TREX2 | 4920707 | 6535 | 0.004 | -0.0501 | No | ||
60 | LAMA5 | 2680722 | 6546 | 0.004 | -0.0505 | No | ||
61 | NPEPPS | 2630731 | 6563 | 0.004 | -0.0513 | No | ||
62 | COL4A3 | 5910075 | 6607 | 0.004 | -0.0535 | No | ||
63 | NBL1 | 2480021 | 6734 | 0.003 | -0.0602 | No | ||
64 | HIF3A | 2630053 2680102 6450364 | 6853 | 0.003 | -0.0665 | No | ||
65 | AP1S2 | 780279 4280707 | 6960 | 0.003 | -0.0722 | No | ||
66 | SLC12A5 | 1980692 | 6961 | 0.003 | -0.0721 | No | ||
67 | NHLH1 | 6100452 | 7193 | 0.002 | -0.0846 | No | ||
68 | SORCS2 | 6350520 | 7241 | 0.002 | -0.0871 | No | ||
69 | FGF11 | 840292 | 7297 | 0.002 | -0.0900 | No | ||
70 | BMP6 | 2100128 | 7330 | 0.002 | -0.0917 | No | ||
71 | PTPRJ | 4010707 | 7635 | 0.001 | -0.1082 | No | ||
72 | CCNL2 | 6520167 | 7961 | -0.000 | -0.1258 | No | ||
73 | KCNB1 | 3610035 | 8065 | -0.000 | -0.1314 | No | ||
74 | PPARA | 2060026 | 8143 | -0.001 | -0.1355 | No | ||
75 | FOXI1 | 3710095 6620195 | 8372 | -0.001 | -0.1479 | No | ||
76 | CHRND | 840403 2260670 | 8515 | -0.002 | -0.1555 | No | ||
77 | MTUS1 | 780348 4920609 | 8638 | -0.002 | -0.1621 | No | ||
78 | ARVCF | 2190537 | 8656 | -0.002 | -0.1629 | No | ||
79 | SOST | 1170195 | 8793 | -0.003 | -0.1702 | No | ||
80 | SFTPC | 3290133 | 8891 | -0.003 | -0.1754 | No | ||
81 | ARHGEF12 | 3990195 | 8997 | -0.003 | -0.1810 | No | ||
82 | NFATC4 | 2470735 | 9153 | -0.004 | -0.1893 | No | ||
83 | GPM6B | 6220458 | 9482 | -0.005 | -0.2070 | No | ||
84 | GPR37 | 2320093 | 9502 | -0.005 | -0.2079 | No | ||
85 | CORO2B | 2340035 4850390 | 9529 | -0.005 | -0.2092 | No | ||
86 | DLL3 | 4010093 | 9532 | -0.005 | -0.2092 | No | ||
87 | GATA2 | 6590280 | 9658 | -0.005 | -0.2158 | No | ||
88 | DOC2A | 6020121 | 9769 | -0.005 | -0.2216 | No | ||
89 | ZNF205 | 6900022 | 9971 | -0.006 | -0.2324 | No | ||
90 | CPA4 | 3610100 | 10045 | -0.006 | -0.2361 | No | ||
91 | GDPD2 | 7000040 | 10224 | -0.007 | -0.2456 | No | ||
92 | CENTG3 | 2470079 4610092 5050170 | 10278 | -0.007 | -0.2483 | No | ||
93 | ALDH1A2 | 2320301 | 10378 | -0.008 | -0.2534 | No | ||
94 | RTN4RL2 | 6450609 | 10509 | -0.008 | -0.2603 | No | ||
95 | ODC1 | 5670168 | 10563 | -0.008 | -0.2629 | No | ||
96 | ROBO3 | 6550408 | 10652 | -0.009 | -0.2674 | No | ||
97 | CALN1 | 3610722 | 10703 | -0.009 | -0.2699 | No | ||
98 | NR4A1 | 6290161 | 10808 | -0.009 | -0.2753 | No | ||
99 | MYOZ3 | 1990138 | 10895 | -0.010 | -0.2797 | No | ||
100 | ANK2 | 6510546 | 10963 | -0.010 | -0.2830 | No | ||
101 | HSD11B2 | 5900053 | 10970 | -0.010 | -0.2831 | No | ||
102 | SLC24A3 | 5080707 | 11279 | -0.011 | -0.2995 | No | ||
103 | CPZ | 70193 | 11282 | -0.011 | -0.2993 | No | ||
104 | GJB2 | 5900609 6200487 | 11322 | -0.012 | -0.3011 | No | ||
105 | IRX6 | 4590025 | 11410 | -0.012 | -0.3054 | No | ||
106 | PPP1R9B | 3130619 | 11732 | -0.014 | -0.3225 | No | ||
107 | RASSF2 | 2480079 5720546 | 11760 | -0.014 | -0.3235 | No | ||
108 | MT3 | 1450537 | 11846 | -0.015 | -0.3277 | No | ||
109 | KCNK12 | 4070072 | 11852 | -0.015 | -0.3276 | No | ||
110 | CHST9 | 4560092 | 11928 | -0.015 | -0.3312 | No | ||
111 | CYP26A1 | 380022 2690600 | 12057 | -0.016 | -0.3377 | No | ||
112 | CALB1 | 460070 | 12242 | -0.018 | -0.3472 | No | ||
113 | POU2F3 | 2030601 | 12466 | -0.019 | -0.3588 | No | ||
114 | FSCN2 | 1230039 | 12490 | -0.020 | -0.3595 | No | ||
115 | TEAD4 | 1850239 6380519 | 12636 | -0.021 | -0.3668 | No | ||
116 | DLL1 | 1770377 | 12807 | -0.023 | -0.3753 | No | ||
117 | DNMT3A | 4050068 4810717 | 12980 | -0.025 | -0.3840 | No | ||
118 | CDH2 | 520435 2450451 2760025 6650477 | 13234 | -0.028 | -0.3969 | No | ||
119 | NOL4 | 5050446 5360519 | 13315 | -0.029 | -0.4005 | No | ||
120 | CANX | 4760402 | 13498 | -0.032 | -0.4094 | No | ||
121 | TNNC2 | 3840079 | 13577 | -0.033 | -0.4127 | No | ||
122 | PRKAG2 | 2340100 | 13820 | -0.037 | -0.4248 | No | ||
123 | PLCB3 | 4670402 | 13869 | -0.038 | -0.4264 | No | ||
124 | HOXB7 | 4540706 4610358 | 13966 | -0.040 | -0.4305 | No | ||
125 | GGN | 1410528 4210082 5290170 | 14054 | -0.042 | -0.4340 | No | ||
126 | FYN | 2100468 4760520 4850687 | 14128 | -0.044 | -0.4367 | No | ||
127 | MDGA1 | 1170139 | 14197 | -0.046 | -0.4391 | No | ||
128 | BRUNOL4 | 4490452 5080451 | 14228 | -0.046 | -0.4395 | No | ||
129 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14267 | -0.047 | -0.4402 | No | ||
130 | PHACTR3 | 3850435 5900445 | 14303 | -0.048 | -0.4408 | No | ||
131 | LRP5 | 2100397 3170484 | 14383 | -0.050 | -0.4437 | No | ||
132 | DNAJB5 | 2900215 | 14457 | -0.052 | -0.4462 | No | ||
133 | SCG2 | 5670438 130671 | 14639 | -0.058 | -0.4544 | No | ||
134 | FGF8 | 6350504 | 14643 | -0.059 | -0.4529 | No | ||
135 | POFUT1 | 1570458 | 14707 | -0.060 | -0.4547 | No | ||
136 | USP2 | 1190292 1240253 4850035 | 14758 | -0.062 | -0.4557 | No | ||
137 | SEMA3F | 5420601 6770731 | 14775 | -0.063 | -0.4548 | No | ||
138 | SYT4 | 5080193 | 15095 | -0.076 | -0.4700 | No | ||
139 | ACTN3 | 3140541 6480598 | 15137 | -0.078 | -0.4700 | No | ||
140 | CXCL14 | 840114 6450324 | 15221 | -0.082 | -0.4722 | No | ||
141 | ITGB4 | 1740021 3840482 | 15402 | -0.093 | -0.4794 | No | ||
142 | TNFRSF21 | 6380100 | 15441 | -0.096 | -0.4788 | No | ||
143 | IGFBP5 | 2360592 | 15508 | -0.100 | -0.4796 | No | ||
144 | INVS | 4200632 6620528 | 15703 | -0.113 | -0.4870 | No | ||
145 | SIPA1 | 5220687 | 15726 | -0.115 | -0.4850 | No | ||
146 | DEF6 | 840593 | 16024 | -0.144 | -0.4971 | No | ||
147 | CORO2A | 3840605 6620390 | 16206 | -0.163 | -0.5023 | No | ||
148 | CRELD1 | 2060253 | 16307 | -0.176 | -0.5029 | No | ||
149 | STC2 | 4920601 | 16393 | -0.187 | -0.5023 | No | ||
150 | IGSF8 | 1580592 | 16486 | -0.198 | -0.5018 | No | ||
151 | ARHGAP24 | 540278 4540025 | 16533 | -0.205 | -0.4986 | No | ||
152 | NEURL | 5390538 | 16648 | -0.220 | -0.4986 | No | ||
153 | CENTB1 | 2120093 | 16675 | -0.223 | -0.4938 | No | ||
154 | ARID5A | 2450133 | 16789 | -0.242 | -0.4932 | No | ||
155 | PSTPIP1 | 3190156 | 17111 | -0.293 | -0.5025 | No | ||
156 | SLC37A4 | 6400079 | 17359 | -0.344 | -0.5063 | Yes | ||
157 | HMGA1 | 6580408 | 17390 | -0.349 | -0.4982 | Yes | ||
158 | SASH1 | 4070270 | 17444 | -0.358 | -0.4911 | Yes | ||
159 | GRB7 | 2100471 | 17483 | -0.366 | -0.4830 | Yes | ||
160 | GPD1 | 2480095 | 17833 | -0.474 | -0.4888 | Yes | ||
161 | GFRA1 | 3610152 | 17836 | -0.478 | -0.4756 | Yes | ||
162 | ELOVL1 | 2450019 4760138 5340685 | 17838 | -0.478 | -0.4623 | Yes | ||
163 | TNFSF13 | 2650170 | 17840 | -0.479 | -0.4491 | Yes | ||
164 | ENO3 | 5270136 | 17901 | -0.501 | -0.4384 | Yes | ||
165 | SELL | 1190500 | 17938 | -0.519 | -0.4259 | Yes | ||
166 | PTK2B | 4730411 | 18025 | -0.567 | -0.4148 | Yes | ||
167 | SMAD3 | 6450671 | 18084 | -0.607 | -0.4010 | Yes | ||
168 | PPOX | 2640678 3850102 | 18090 | -0.614 | -0.3842 | Yes | ||
169 | AIG1 | 2450091 | 18259 | -0.795 | -0.3712 | Yes | ||
170 | HEYL | 5860528 | 18352 | -0.937 | -0.3502 | Yes | ||
171 | TTC17 | 2470440 | 18373 | -0.967 | -0.3243 | Yes | ||
172 | RANGAP1 | 2320593 6650601 | 18486 | -1.244 | -0.2958 | Yes | ||
173 | HES6 | 540411 6550504 | 18520 | -1.504 | -0.2558 | Yes | ||
174 | CKM | 1450524 | 18536 | -1.575 | -0.2128 | Yes | ||
175 | POLR1D | 70082 450750 6040458 | 18579 | -2.354 | -0.1495 | Yes | ||
176 | IGF2 | 6510020 | 18590 | -2.564 | -0.0787 | Yes | ||
177 | GNAS | 630441 1850373 4050152 | 18597 | -2.879 | 0.0010 | Yes |