Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$CART1_01 |
Enrichment Score (ES) | -0.5111231 |
Normalized Enrichment Score (NES) | -1.2918069 |
Nominal p-value | 0.05107084 |
FDR q-value | 0.7951194 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | BCL6 | 940100 | 185 | 0.930 | 0.0338 | No | ||
2 | OTX2 | 1190471 | 499 | 0.622 | 0.0461 | No | ||
3 | PTMA | 5570148 | 539 | 0.603 | 0.0724 | No | ||
4 | MBNL2 | 3450707 | 711 | 0.509 | 0.0871 | No | ||
5 | SOX4 | 2260091 | 720 | 0.506 | 0.1105 | No | ||
6 | ZDHHC21 | 2370338 | 851 | 0.449 | 0.1246 | No | ||
7 | PTPRC | 130402 5290148 | 1289 | 0.312 | 0.1156 | No | ||
8 | ZNF148 | 6420403 | 1320 | 0.302 | 0.1282 | No | ||
9 | NFIX | 2450152 | 1365 | 0.289 | 0.1394 | No | ||
10 | GOLGA1 | 5860471 | 1628 | 0.229 | 0.1360 | No | ||
11 | BBX | 6520112 | 2005 | 0.167 | 0.1236 | No | ||
12 | WARS2 | 840605 4590280 | 2566 | 0.101 | 0.0980 | No | ||
13 | SEPHS1 | 4230725 | 2634 | 0.095 | 0.0988 | No | ||
14 | RCHY1 | 3800739 | 2677 | 0.091 | 0.1008 | No | ||
15 | CHD2 | 4070039 | 2762 | 0.085 | 0.1002 | No | ||
16 | ACADSB | 520170 | 2765 | 0.084 | 0.1041 | No | ||
17 | EN1 | 5360168 7050025 | 2979 | 0.069 | 0.0958 | No | ||
18 | TCEB3 | 5890156 | 3016 | 0.066 | 0.0970 | No | ||
19 | PCF11 | 1240180 | 3114 | 0.061 | 0.0946 | No | ||
20 | GPR85 | 5130750 5910020 | 3178 | 0.056 | 0.0938 | No | ||
21 | ADAM11 | 1050008 3130494 | 3259 | 0.052 | 0.0919 | No | ||
22 | ERG | 50154 1770739 | 3416 | 0.045 | 0.0856 | No | ||
23 | STC1 | 360161 | 3464 | 0.043 | 0.0851 | No | ||
24 | TRAF3 | 5690647 | 3649 | 0.036 | 0.0769 | No | ||
25 | CBL | 6380068 | 3650 | 0.036 | 0.0785 | No | ||
26 | RAB6A | 3840463 4780731 | 3663 | 0.035 | 0.0796 | No | ||
27 | TTR | 4150072 | 3665 | 0.035 | 0.0812 | No | ||
28 | RNF12 | 6860717 | 3760 | 0.033 | 0.0776 | No | ||
29 | ELF5 | 3140156 5220020 | 3802 | 0.032 | 0.0769 | No | ||
30 | RAB2B | 6200091 | 3819 | 0.031 | 0.0775 | No | ||
31 | PRRX1 | 4120193 4480390 | 4054 | 0.025 | 0.0660 | No | ||
32 | ACBD5 | 3440397 6020600 | 4090 | 0.024 | 0.0653 | No | ||
33 | MID1 | 4070114 4760458 | 4285 | 0.021 | 0.0558 | No | ||
34 | CHRDL1 | 1580037 6380204 | 4394 | 0.019 | 0.0508 | No | ||
35 | PVRL3 | 1400324 4200593 6650128 | 4455 | 0.019 | 0.0485 | No | ||
36 | BACE2 | 4060170 5690100 6220133 | 4510 | 0.018 | 0.0464 | No | ||
37 | LRRC15 | 3940609 | 4524 | 0.018 | 0.0465 | No | ||
38 | OTP | 2630070 | 4870 | 0.014 | 0.0285 | No | ||
39 | PTF1A | 6450377 | 4883 | 0.014 | 0.0285 | No | ||
40 | PRSS12 | 1230364 6220059 | 5070 | 0.012 | 0.0189 | No | ||
41 | KLHL13 | 6590731 | 5335 | 0.010 | 0.0051 | No | ||
42 | CRTAC1 | 840408 | 5382 | 0.010 | 0.0031 | No | ||
43 | HOXB6 | 4210739 | 5688 | 0.008 | -0.0130 | No | ||
44 | BAMBI | 6650463 | 5709 | 0.008 | -0.0138 | No | ||
45 | NPTX2 | 70021 | 5764 | 0.008 | -0.0163 | No | ||
46 | CDKL5 | 2450070 | 5794 | 0.007 | -0.0176 | No | ||
47 | HIPK3 | 4540601 | 5801 | 0.007 | -0.0175 | No | ||
48 | NETO1 | 3830722 4200332 | 5808 | 0.007 | -0.0175 | No | ||
49 | KYNU | 1410435 | 5919 | 0.007 | -0.0232 | No | ||
50 | UNC13B | 130735 | 5976 | 0.007 | -0.0259 | No | ||
51 | LGALS12 | 3940242 | 6460 | 0.004 | -0.0518 | No | ||
52 | GABRA6 | 4120520 | 6778 | 0.003 | -0.0688 | No | ||
53 | EFEMP1 | 5860324 | 6787 | 0.003 | -0.0691 | No | ||
54 | MYT1 | 6770524 | 6945 | 0.003 | -0.0775 | No | ||
55 | SALL1 | 5420020 7050195 | 6957 | 0.003 | -0.0779 | No | ||
56 | TEAD3 | 2320142 | 6999 | 0.003 | -0.0800 | No | ||
57 | MAL2 | 2760706 | 7047 | 0.002 | -0.0825 | No | ||
58 | ZIC3 | 380020 | 7085 | 0.002 | -0.0844 | No | ||
59 | ARRB1 | 2650670 2690195 4920592 6660121 | 7347 | 0.002 | -0.0984 | No | ||
60 | NOS1 | 5860129 | 7464 | 0.001 | -0.1047 | No | ||
61 | ROR1 | 6220026 | 7563 | 0.001 | -0.1099 | No | ||
62 | SLITRK5 | 6590292 | 7654 | 0.001 | -0.1148 | No | ||
63 | CALB2 | 6130170 6590368 | 7665 | 0.001 | -0.1153 | No | ||
64 | SLC26A3 | 380750 | 7769 | 0.000 | -0.1208 | No | ||
65 | LECT1 | 2640528 | 7777 | 0.000 | -0.1212 | No | ||
66 | ELP4 | 1230576 | 7927 | -0.000 | -0.1293 | No | ||
67 | PDGFRA | 2940332 | 8180 | -0.001 | -0.1429 | No | ||
68 | CNTNAP4 | 3830364 5340347 | 8270 | -0.001 | -0.1476 | No | ||
69 | HOXA5 | 6840026 | 8443 | -0.002 | -0.1569 | No | ||
70 | MTUS1 | 780348 4920609 | 8638 | -0.002 | -0.1673 | No | ||
71 | ESRRG | 4010181 | 8681 | -0.002 | -0.1694 | No | ||
72 | LRFN5 | 6650088 | 8744 | -0.002 | -0.1727 | No | ||
73 | CYP46A1 | 2470332 | 9199 | -0.004 | -0.1971 | No | ||
74 | EYA1 | 1450278 5220390 | 9222 | -0.004 | -0.1981 | No | ||
75 | GRM8 | 4780082 | 9241 | -0.004 | -0.1989 | No | ||
76 | JPH3 | 780397 | 9272 | -0.004 | -0.2003 | No | ||
77 | ACCN1 | 2060139 2190541 | 9403 | -0.004 | -0.2072 | No | ||
78 | PAK3 | 4210136 | 9648 | -0.005 | -0.2202 | No | ||
79 | PBX1 | 6660301 | 9693 | -0.005 | -0.2223 | No | ||
80 | EPHA7 | 1190288 4010278 | 9702 | -0.005 | -0.2225 | No | ||
81 | HOXA11 | 6980133 | 9741 | -0.005 | -0.2243 | No | ||
82 | POGZ | 870348 7040286 | 9967 | -0.006 | -0.2362 | No | ||
83 | PHOX2B | 5270075 | 10089 | -0.006 | -0.2424 | No | ||
84 | CDH6 | 4730541 | 10209 | -0.007 | -0.2486 | No | ||
85 | PCDHB15 | 520725 | 10369 | -0.007 | -0.2568 | No | ||
86 | MOXD1 | 2450301 | 10811 | -0.009 | -0.2803 | No | ||
87 | PRDM1 | 3170347 3520301 | 10835 | -0.009 | -0.2811 | No | ||
88 | BNC2 | 4810603 | 10884 | -0.010 | -0.2832 | No | ||
89 | MYH2 | 2340433 | 11069 | -0.010 | -0.2927 | No | ||
90 | NEUROD6 | 4670731 | 11115 | -0.011 | -0.2946 | No | ||
91 | MEF2C | 670025 780338 | 11283 | -0.011 | -0.3031 | No | ||
92 | CALD1 | 1770129 1940397 | 11382 | -0.012 | -0.3079 | No | ||
93 | IRX2 | 870438 | 11431 | -0.012 | -0.3099 | No | ||
94 | CLCA3 | 6510167 | 11536 | -0.013 | -0.3149 | No | ||
95 | HOXB3 | 520292 | 11609 | -0.013 | -0.3182 | No | ||
96 | BCL11A | 6860369 | 11620 | -0.013 | -0.3181 | No | ||
97 | ZFPM2 | 460072 | 11749 | -0.014 | -0.3244 | No | ||
98 | PPIL5 | 3850619 | 11802 | -0.014 | -0.3265 | No | ||
99 | LOXHD1 | 520039 | 12026 | -0.016 | -0.3379 | No | ||
100 | DLL4 | 6400403 | 12152 | -0.017 | -0.3439 | No | ||
101 | HOXB5 | 2900538 | 12212 | -0.017 | -0.3462 | No | ||
102 | GBX2 | 3940736 | 12434 | -0.019 | -0.3573 | No | ||
103 | RIMS2 | 670725 | 12541 | -0.020 | -0.3621 | No | ||
104 | HOXA3 | 3610632 6020358 | 12594 | -0.021 | -0.3639 | No | ||
105 | PDGFC | 4200133 | 12727 | -0.022 | -0.3701 | No | ||
106 | RFX3 | 520121 4280519 5570519 6100184 | 12868 | -0.023 | -0.3765 | No | ||
107 | OGG1 | 1940279 | 12877 | -0.024 | -0.3759 | No | ||
108 | CREB5 | 2320368 | 12960 | -0.024 | -0.3791 | No | ||
109 | HSD3B7 | 1410129 | 13018 | -0.025 | -0.3810 | No | ||
110 | WNT3 | 2360685 | 13076 | -0.026 | -0.3829 | No | ||
111 | FOXP2 | 3520561 4150372 4760524 | 13106 | -0.026 | -0.3832 | No | ||
112 | PELI2 | 1940364 | 13306 | -0.029 | -0.3927 | No | ||
113 | NOL4 | 5050446 5360519 | 13315 | -0.029 | -0.3917 | No | ||
114 | PAPPA | 4230463 | 13641 | -0.034 | -0.4077 | No | ||
115 | YARS | 70739 | 13793 | -0.037 | -0.4141 | No | ||
116 | C1QTNF6 | 2030592 | 13862 | -0.038 | -0.4160 | No | ||
117 | HOXB7 | 4540706 4610358 | 13966 | -0.040 | -0.4197 | No | ||
118 | FYN | 2100468 4760520 4850687 | 14128 | -0.044 | -0.4264 | No | ||
119 | LMO4 | 3800746 | 14148 | -0.045 | -0.4253 | No | ||
120 | SOX5 | 2370576 2900167 3190128 5050528 | 14189 | -0.045 | -0.4253 | No | ||
121 | A2BP1 | 2370390 4590593 5550014 | 14204 | -0.046 | -0.4239 | No | ||
122 | ACCN2 | 6450465 | 14463 | -0.053 | -0.4354 | No | ||
123 | NRAS | 6900577 | 14481 | -0.053 | -0.4338 | No | ||
124 | FGF13 | 630575 1570440 5360121 | 14771 | -0.063 | -0.4465 | No | ||
125 | SLC16A9 | 6220497 | 14871 | -0.067 | -0.4487 | No | ||
126 | STOML2 | 1940487 | 15135 | -0.078 | -0.4593 | No | ||
127 | POU2F1 | 70577 430373 4850324 5910056 | 15161 | -0.079 | -0.4570 | No | ||
128 | HESX1 | 4050746 | 15228 | -0.083 | -0.4566 | No | ||
129 | FOXB1 | 4920270 5290463 | 15331 | -0.089 | -0.4580 | No | ||
130 | TACSTD2 | 6660341 | 15336 | -0.089 | -0.4540 | No | ||
131 | CFL2 | 380239 6200368 | 15401 | -0.093 | -0.4531 | No | ||
132 | ITPR3 | 4010632 | 15594 | -0.105 | -0.4586 | No | ||
133 | RFXANK | 4010341 | 15605 | -0.106 | -0.4541 | No | ||
134 | ACACA | 2490612 2680369 | 16012 | -0.142 | -0.4694 | No | ||
135 | NPHP4 | 1190433 | 16033 | -0.145 | -0.4637 | No | ||
136 | DNASE1L3 | 670086 | 16087 | -0.150 | -0.4595 | No | ||
137 | GPX1 | 4150093 | 16587 | -0.212 | -0.4765 | No | ||
138 | RPS19 | 5860066 | 17227 | -0.317 | -0.4962 | Yes | ||
139 | KCTD15 | 2810735 | 17285 | -0.329 | -0.4838 | Yes | ||
140 | PRKAG1 | 6450091 | 17557 | -0.382 | -0.4805 | Yes | ||
141 | MAP2K5 | 2030440 | 17585 | -0.391 | -0.4636 | Yes | ||
142 | ZNF219 | 5900471 | 17759 | -0.448 | -0.4518 | Yes | ||
143 | SERTAD4 | 130593 | 18059 | -0.589 | -0.4403 | Yes | ||
144 | CDKN2C | 5050750 5130148 | 18240 | -0.763 | -0.4141 | Yes | ||
145 | CLDN4 | 4920739 | 18465 | -1.162 | -0.3716 | Yes | ||
146 | CABLES1 | 610253 2190504 | 18523 | -1.520 | -0.3031 | Yes | ||
147 | DSCR1 | 4540048 6220039 | 18535 | -1.573 | -0.2297 | Yes | ||
148 | PRDX2 | 6760095 4010619 5340577 | 18614 | -4.972 | 0.0001 | Yes |