Details for gene set V$AREB6

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	V$AREB6_03
Enrichment Score (ES)	-0.526187
Normalized Enrichment Score (NES)	-1.3598515
Nominal p-value	0.017027864
FDR q-value	0.7281782
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CIZ1	4150128 6130484	92	1.218	0.0400	No
2	WDR5	4150736	428	0.664	0.0464	No
3	ROCK1	130044	640	0.542	0.0550	No
4	BCL7A	4560095	735	0.495	0.0681	No
5	NCOR1	3710132	848	0.450	0.0787	No
6	FLNB	2510575	978	0.405	0.0867	No
7	SFRS7	2760408	1120	0.354	0.0921	No
8	PLAGL2	1770148	1306	0.305	0.0933	No
9	MAPK14	5290731	1470	0.262	0.0942	No
10	PPP1R16B	3520300	1730	0.212	0.0880	No
11	SLC7A11	2850138	1849	0.190	0.0886	No
12	CXCR4	4590519	2146	0.146	0.0780	No
13	LYL1	2900242	2213	0.136	0.0794	No
14	CAMTA2	3990075	2313	0.125	0.0787	No
15	MYH10	2640673	2489	0.107	0.0731	No
16	SLC16A6	1690156	2524	0.104	0.0751	No
17	CHRNB1	1190671	2664	0.092	0.0710	No
18	LSP1	2350091	2667	0.092	0.0743	No
19	NTRK3	4050687 4070167 4610026 6100484	2796	0.083	0.0704	No
20	L3MBTL2	6020341	2909	0.074	0.0671	No
21	LIMK2	2650446 4050164	3037	0.065	0.0626	No
22	THRA	6770341 110164 1990600	3137	0.059	0.0594	No
23	SSBP4	2570735	3185	0.056	0.0589	No
24	PNOC	1990114	3263	0.052	0.0567	No
25	FA2H	730672	3299	0.050	0.0566	No
26	SH2D3C	3060014	3320	0.049	0.0573	No
27	NRF1	2650195	3507	0.042	0.0488	No
28	ADAM12	3390132 4070347	3596	0.038	0.0454	No
29	MKL1	6840161	3623	0.037	0.0454	No
30	SEMA4G	5890026	3825	0.031	0.0357	No
31	CRB3	6940091	3983	0.027	0.0281	No
32	MLLT3	510204 3850722 6200088	4152	0.023	0.0199	No
33	CCKAR	4210079	4276	0.021	0.0140	No
34	POU4F2	2120195 2570022	4288	0.021	0.0142	No
35	JMJD1C	940575 2120025	4403	0.019	0.0087	No
36	PDGFA	6020095	4472	0.018	0.0057	No
37	USP15	610592 3520504	4508	0.018	0.0045	No
38	ITGA6	3830129	4560	0.017	0.0024	No
39	PLCB2	360132	4569	0.017	0.0026	No
40	ELMO1	110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180	4731	0.015	-0.0056	No
41	PIM2	840136 5720692 7100577	4949	0.013	-0.0169	No
42	FUT8	1340068 2340056	5196	0.011	-0.0298	No
43	DSCAM	1780050 2450731 2810438	5269	0.011	-0.0333	No
44	PVRL4	2340048 6220195	5276	0.011	-0.0333	No
45	SDPR	3360292	5454	0.009	-0.0425	No
46	NGFB	2630019	5485	0.009	-0.0438	No
47	PFTK1	1780181	5521	0.009	-0.0454	No
48	DSCAML1	1850403 5550079	5653	0.008	-0.0522	No
49	JUB	5860711 5900500	5677	0.008	-0.0531	No
50	DIO2	380504 540403	5899	0.007	-0.0648	No
51	TCF2	870338 5050632	5950	0.007	-0.0673	No
52	ZNF462	6900100	6102	0.006	-0.0753	No
53	GPR126	6650204	6339	0.005	-0.0879	No
54	ARTN	360670 1170333 1500520	6466	0.004	-0.0945	No
55	NPEPPS	2630731	6563	0.004	-0.0996	No
56	AP1S2	780279 4280707	6960	0.003	-0.1210	No
57	SSX2IP	4610176	7037	0.002	-0.1250	No
58	SLC9A7	5360301	7150	0.002	-0.1310	No
59	FST	1110600	7185	0.002	-0.1327	No
60	MMP16	2680139	7380	0.001	-0.1432	No
61	TACSTD1	3780025	7485	0.001	-0.1488	No
62	KHDRBS2	3520717	7537	0.001	-0.1515	No
63	TLX2	1090128 2900451	7734	0.000	-0.1621	No
64	CRMP1	4810014	7839	0.000	-0.1678	No
65	EDG1	4200619	7994	-0.000	-0.1761	No
66	TECTA	2570372	8039	-0.000	-0.1785	No
67	CHRM1	4280619	8046	-0.000	-0.1788	No
68	SYT2	60609	8157	-0.001	-0.1847	No
69	NGFR	3140102	8334	-0.001	-0.1942	No
70	RPS6KB1	1450427 5080110 6200563	8448	-0.002	-0.2003	No
71	SLC30A3	1850451	8559	-0.002	-0.2062	No
72	DDAH1	6400750	8597	-0.002	-0.2081	No
73	MTUS1	780348 4920609	8638	-0.002	-0.2102	No
74	CHX10	3830184	8708	-0.002	-0.2138	No
75	LRRN1	3290154	8811	-0.003	-0.2193	No
76	CACNB3	2480035 4540184	9115	-0.003	-0.2356	No
77	EYA1	1450278 5220390	9222	-0.004	-0.2412	No
78	ACTA1	840538	9281	-0.004	-0.2442	No
79	HOXA11	6980133	9741	-0.005	-0.2689	No
80	DOC2A	6020121	9769	-0.005	-0.2701	No
81	FBXO24	1230132 4610121	9851	-0.006	-0.2743	No
82	JAG1	3440390	10130	-0.007	-0.2891	No
83	EDG2	6290215	10377	-0.008	-0.3022	No
84	PDE1C	3940600	10526	-0.008	-0.3099	No
85	HCRTR1	1580273	10721	-0.009	-0.3201	No
86	MAB21L1	1450634 1580092	10816	-0.009	-0.3248	No
87	FOXA1	3710609	10870	-0.009	-0.3274	No
88	SSH3	6290110 6650497	11031	-0.010	-0.3357	No
89	MESDC1	2030019	11048	-0.010	-0.3361	No
90	DSTN	3140592	11054	-0.010	-0.3360	No
91	IL17C	5690347	11177	-0.011	-0.3422	No
92	SLC24A3	5080707	11279	-0.011	-0.3473	No
93	PPP1R14C	2570692 5290204 6420184	11645	-0.013	-0.3666	No
94	KLHL1	6350021	11655	-0.013	-0.3666	No
95	DSG2	360528 2630603	11709	-0.014	-0.3689	No
96	SCNN1G	520600	11814	-0.014	-0.3740	No
97	ERBB3	5890372	11878	-0.015	-0.3769	No
98	TNNT3	1570239	11940	-0.015	-0.3797	No
99	SMTN	670563 1190438	12004	-0.016	-0.3825	No
100	FGF9	1050195	12113	-0.016	-0.3877	No
101	DMD	1740041 3990332	12328	-0.018	-0.3987	No
102	POU4F1	2260315	12336	-0.018	-0.3984	No
103	KCNJ11	2510131	12471	-0.019	-0.4049	No
104	SCN3B	840112 1780152 5910685 6100131	12546	-0.020	-0.4082	No
105	IL4	6020537	12559	-0.020	-0.4081	No
106	LAMC2	450692 2680041 4200059 4670148	12714	-0.022	-0.4156	No
107	CD2AP	1940369	12742	-0.022	-0.4163	No
108	CDH3	5390112 6860603	12751	-0.022	-0.4159	No
109	NFE2	3710373	12765	-0.022	-0.4158	No
110	DNMT3A	4050068 4810717	12980	-0.025	-0.4264	No
111	H2AFY	4730750	13127	-0.027	-0.4334	No
112	SCUBE2	2850315 5130040	13261	-0.028	-0.4395	No
113	LRCH4	5220279 6510026	13424	-0.031	-0.4472	No
114	SNAP25	360520	13442	-0.031	-0.4469	No
115	AHR	4560671	13468	-0.031	-0.4471	No
116	TACC2	580092 1400364 2650497 2690315 5360338	13596	-0.033	-0.4528	No
117	CEL	2640278	13653	-0.034	-0.4546	No
118	GNG8	4920358	13803	-0.037	-0.4613	No
119	WDR6	7050154	14146	-0.045	-0.4782	No
120	PHACTR3	3850435 5900445	14303	-0.048	-0.4848	No
121	KREMEN2	110025	14332	-0.049	-0.4846	No
122	ELL3	1770484	14375	-0.050	-0.4850	No
123	LRP5	2100397 3170484	14383	-0.050	-0.4835	No
124	HNF4A	6620440	14474	-0.053	-0.4864	No
125	IRF6	840241 2640139 4050373 6840471	14527	-0.055	-0.4872	No
126	KIF1C	2480484	14528	-0.055	-0.4852	No
127	FGF8	6350504	14643	-0.059	-0.4892	No
128	PDE11A	2190215	14693	-0.060	-0.4897	No
129	POFUT1	1570458	14707	-0.060	-0.4882	No
130	SEMA3F	5420601 6770731	14775	-0.063	-0.4895	No
131	APP	2510053	14910	-0.068	-0.4942	No
132	ALX3	50497	14962	-0.070	-0.4944	No
133	NR4A2	60273	15039	-0.073	-0.4958	No
134	ACCN4	6380551	15043	-0.073	-0.4933	No
135	RGMA	2450711	15151	-0.079	-0.4962	No
136	NUMBL	6130360 6200333	15240	-0.083	-0.4979	No
137	PHF1	4010577 6420053	15333	-0.089	-0.4996	No
138	ITGB4	1740021 3840482	15402	-0.093	-0.4998	No
139	CBX8	50671	15674	-0.111	-0.5104	No
140	VGLL4	6860463	15966	-0.137	-0.5211	Yes
141	TEC	1400576	16025	-0.144	-0.5190	Yes
142	CRSP7	4230408	16055	-0.147	-0.5151	Yes
143	FGR	3780047	16095	-0.150	-0.5117	Yes
144	E2F1	5360093	16136	-0.155	-0.5081	Yes
145	HDAC3	4060072	16189	-0.161	-0.5050	Yes
146	CRELD1	2060253	16307	-0.176	-0.5048	Yes
147	VAT1	1050040	16319	-0.177	-0.4989	Yes
148	EHD1	3840731	16384	-0.186	-0.4955	Yes
149	TNNI1	3710040	16564	-0.209	-0.4974	Yes
150	SERF2	5720010	16654	-0.220	-0.4941	Yes
151	PARD6A	4120170	17016	-0.276	-0.5035	Yes
152	CUEDC1	1660463	17025	-0.278	-0.4936	Yes
153	MRPL14	2370168	17057	-0.284	-0.4848	Yes
154	REPIN1	6110400	17389	-0.349	-0.4899	Yes
155	PNKP	4610685 5720605	17757	-0.447	-0.4932	Yes
156	ALS2CR2	6450128 7100092	17807	-0.464	-0.4788	Yes
157	GPD1	2480095	17833	-0.474	-0.4626	Yes
158	ARFIP2	1850301 4670180	17865	-0.489	-0.4462	Yes
159	GNA12	1230301	17879	-0.495	-0.4286	Yes
160	DGKA	5720152 5890328	18038	-0.577	-0.4159	Yes
161	FXC1	3710053 4060575	18043	-0.580	-0.3947	Yes
162	EXTL3	540309 3130215 5860500	18334	-0.918	-0.3765	Yes
163	DGKZ	3460041 6400129	18483	-1.227	-0.3391	Yes
164	DNMT3B	2320138 4070059	18522	-1.518	-0.2851	Yes
165	SSBP3	870717 1050377 7040551	18524	-1.522	-0.2289	Yes
166	IGF2	6510020	18590	-2.564	-0.1377	Yes
167	FAF1	2450717 2510121 4730156	18608	-3.763	0.0004	Yes