Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q4 |
Enrichment Score (ES) | -0.50276387 |
Normalized Enrichment Score (NES) | -1.316587 |
Nominal p-value | 0.032467533 |
FDR q-value | 0.92869294 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CIZ1 | 4150128 6130484 | 92 | 1.218 | 0.0276 | No | ||
2 | TCF12 | 3610324 7000156 | 219 | 0.880 | 0.0442 | No | ||
3 | SRPK2 | 6380341 | 304 | 0.780 | 0.0605 | No | ||
4 | RTN4 | 50725 630647 870097 870184 | 402 | 0.685 | 0.0736 | No | ||
5 | EEF1A1 | 1980193 1990195 4670735 | 693 | 0.517 | 0.0716 | No | ||
6 | PKN3 | 2260538 | 702 | 0.513 | 0.0849 | No | ||
7 | TRIM8 | 6130441 | 733 | 0.496 | 0.0965 | No | ||
8 | EIF4G1 | 4070446 | 800 | 0.472 | 0.1056 | No | ||
9 | RBBP7 | 430113 450450 2370309 | 1106 | 0.357 | 0.0986 | No | ||
10 | RPA3 | 5700136 | 1113 | 0.356 | 0.1077 | No | ||
11 | ICK | 1580746 3140021 | 1348 | 0.294 | 0.1029 | No | ||
12 | LAMB3 | 7100301 | 1388 | 0.282 | 0.1083 | No | ||
13 | PDAP1 | 1410735 | 1389 | 0.282 | 0.1159 | No | ||
14 | KCNH2 | 1170451 | 1437 | 0.268 | 0.1205 | No | ||
15 | IL10 | 2340685 2640541 2850403 6590286 | 1468 | 0.263 | 0.1259 | No | ||
16 | NEFH | 630239 | 1565 | 0.242 | 0.1271 | No | ||
17 | XPOT | 7050184 | 1670 | 0.222 | 0.1274 | No | ||
18 | PSMD4 | 430068 | 1717 | 0.215 | 0.1307 | No | ||
19 | DTX2 | 4210041 7000008 | 1725 | 0.213 | 0.1360 | No | ||
20 | TGFBR2 | 1780711 1980537 6550398 | 1826 | 0.195 | 0.1358 | No | ||
21 | ABHD4 | 6760450 | 1856 | 0.188 | 0.1392 | No | ||
22 | APOBEC1 | 4610022 | 2070 | 0.157 | 0.1319 | No | ||
23 | ABI3 | 1740563 | 2107 | 0.151 | 0.1339 | No | ||
24 | NFRKB | 3130538 | 2226 | 0.135 | 0.1312 | No | ||
25 | SCOC | 610048 2230053 | 2247 | 0.133 | 0.1336 | No | ||
26 | XLKD1 | 520441 | 2361 | 0.120 | 0.1307 | No | ||
27 | SLC16A6 | 1690156 | 2524 | 0.104 | 0.1247 | No | ||
28 | COL27A1 | 1740390 | 2538 | 0.103 | 0.1267 | No | ||
29 | MAP2K1 | 840739 | 2547 | 0.102 | 0.1290 | No | ||
30 | LRRFIP2 | 670575 730152 6590438 | 2736 | 0.086 | 0.1211 | No | ||
31 | KCNN4 | 2680129 | 2795 | 0.083 | 0.1202 | No | ||
32 | UBE3A | 1240152 2690438 5860609 | 2830 | 0.080 | 0.1204 | No | ||
33 | PDE4D | 2470528 6660014 | 2880 | 0.076 | 0.1198 | No | ||
34 | POLR3E | 380152 | 2996 | 0.068 | 0.1154 | No | ||
35 | MCART1 | 5270059 | 3049 | 0.065 | 0.1143 | No | ||
36 | PDGFRB | 6450279 | 3105 | 0.061 | 0.1130 | No | ||
37 | CORO1C | 4570397 | 3112 | 0.061 | 0.1143 | No | ||
38 | STX17 | 2260037 | 3149 | 0.059 | 0.1139 | No | ||
39 | RABEP1 | 4760427 6200463 | 3223 | 0.054 | 0.1113 | No | ||
40 | CASK | 2340215 3290576 6770215 | 3258 | 0.052 | 0.1109 | No | ||
41 | LAMC1 | 4730025 | 3413 | 0.045 | 0.1037 | No | ||
42 | ZIC4 | 1500082 | 3443 | 0.044 | 0.1033 | No | ||
43 | RIN1 | 510593 | 3517 | 0.041 | 0.1005 | No | ||
44 | BAZ2A | 730184 | 3525 | 0.041 | 0.1012 | No | ||
45 | ROCK2 | 1780035 5720025 | 3714 | 0.034 | 0.0919 | No | ||
46 | APBA2BP | 5700341 | 3818 | 0.031 | 0.0872 | No | ||
47 | UCHL3 | 1240735 | 4281 | 0.021 | 0.0627 | No | ||
48 | PITPNC1 | 3990017 | 4409 | 0.019 | 0.0563 | No | ||
49 | LRRC15 | 3940609 | 4524 | 0.018 | 0.0506 | No | ||
50 | TIAL1 | 4150048 6510605 | 4834 | 0.014 | 0.0342 | No | ||
51 | RAD23B | 2190671 | 4843 | 0.014 | 0.0341 | No | ||
52 | PIM2 | 840136 5720692 7100577 | 4949 | 0.013 | 0.0288 | No | ||
53 | PSMD11 | 2340538 6510053 | 5043 | 0.012 | 0.0241 | No | ||
54 | CDKN1A | 4050088 6400706 | 5145 | 0.011 | 0.0189 | No | ||
55 | IL6 | 380133 | 5316 | 0.010 | 0.0099 | No | ||
56 | LRP1B | 1450193 | 5326 | 0.010 | 0.0097 | No | ||
57 | CMAS | 2190129 | 5759 | 0.008 | -0.0135 | No | ||
58 | CREM | 840156 6380438 6660041 6660168 | 5828 | 0.007 | -0.0170 | No | ||
59 | GOLGA4 | 460300 | 5850 | 0.007 | -0.0180 | No | ||
60 | UCN2 | 4590372 | 5879 | 0.007 | -0.0193 | No | ||
61 | LIFR | 3360068 3830102 | 6180 | 0.006 | -0.0354 | No | ||
62 | GNAI1 | 4560390 | 6364 | 0.005 | -0.0452 | No | ||
63 | FAP | 4560019 | 6584 | 0.004 | -0.0570 | No | ||
64 | EDN1 | 1770047 | 6600 | 0.004 | -0.0577 | No | ||
65 | FGF12 | 1740446 2360037 | 6946 | 0.003 | -0.0764 | No | ||
66 | S100A5 | 4120592 | 6972 | 0.003 | -0.0776 | No | ||
67 | AKAP1 | 110148 1740735 2260019 7000563 | 7026 | 0.003 | -0.0804 | No | ||
68 | IL23A | 6290044 | 7104 | 0.002 | -0.0846 | No | ||
69 | FGF11 | 840292 | 7297 | 0.002 | -0.0949 | No | ||
70 | CCL22 | 6380086 | 7349 | 0.002 | -0.0977 | No | ||
71 | PTPRN | 5900577 | 7449 | 0.001 | -0.1030 | No | ||
72 | FBXW11 | 6450632 | 7459 | 0.001 | -0.1035 | No | ||
73 | USP13 | 1450670 | 7517 | 0.001 | -0.1065 | No | ||
74 | AKT3 | 1580270 3290278 | 7974 | -0.000 | -0.1313 | No | ||
75 | IL1RN | 2370333 | 7976 | -0.000 | -0.1313 | No | ||
76 | EFNA1 | 3840672 | 8028 | -0.000 | -0.1341 | No | ||
77 | PAX9 | 3850519 | 8110 | -0.001 | -0.1384 | No | ||
78 | MMP7 | 1780497 | 8489 | -0.002 | -0.1589 | No | ||
79 | GAB2 | 1410280 2340520 4280040 | 8525 | -0.002 | -0.1608 | No | ||
80 | ZIC1 | 670113 | 8576 | -0.002 | -0.1634 | No | ||
81 | HOXD3 | 6450154 | 8625 | -0.002 | -0.1660 | No | ||
82 | AP2B1 | 1450184 2370148 3520139 4850593 | 8742 | -0.002 | -0.1722 | No | ||
83 | PLAC1 | 2350594 | 8884 | -0.003 | -0.1798 | No | ||
84 | PTPRH | 3870070 | 8946 | -0.003 | -0.1830 | No | ||
85 | ANXA7 | 6110446 | 8963 | -0.003 | -0.1838 | No | ||
86 | EVI2B | 1050465 | 8987 | -0.003 | -0.1850 | No | ||
87 | MAPRE3 | 7050504 | 9213 | -0.004 | -0.1971 | No | ||
88 | EYA1 | 1450278 5220390 | 9222 | -0.004 | -0.1974 | No | ||
89 | TRPV3 | 540341 | 9289 | -0.004 | -0.2009 | No | ||
90 | IL9 | 3440338 | 9344 | -0.004 | -0.2037 | No | ||
91 | SH3RF2 | 6200600 | 9656 | -0.005 | -0.2204 | No | ||
92 | CRYBA2 | 5900138 | 9667 | -0.005 | -0.2208 | No | ||
93 | EIF3S1 | 6130368 6770044 | 9725 | -0.005 | -0.2238 | No | ||
94 | HOXA11 | 6980133 | 9741 | -0.005 | -0.2245 | No | ||
95 | WDFY3 | 3610041 4560333 4570273 | 9963 | -0.006 | -0.2363 | No | ||
96 | GSN | 3830168 | 9984 | -0.006 | -0.2372 | No | ||
97 | IBRDC2 | 5130041 | 10160 | -0.007 | -0.2465 | No | ||
98 | PCDH9 | 2100136 | 10213 | -0.007 | -0.2492 | No | ||
99 | ST18 | 5720537 | 10225 | -0.007 | -0.2496 | No | ||
100 | BMP2 | 6620687 | 10310 | -0.007 | -0.2539 | No | ||
101 | BNIP3 | 3140270 | 10311 | -0.007 | -0.2537 | No | ||
102 | CMYA1 | 6900632 | 10404 | -0.008 | -0.2585 | No | ||
103 | PSMA3 | 5900047 7040161 | 10426 | -0.008 | -0.2595 | No | ||
104 | LPP | 1660541 | 10447 | -0.008 | -0.2603 | No | ||
105 | MYBPH | 2190711 | 10575 | -0.008 | -0.2670 | No | ||
106 | PRDM1 | 3170347 3520301 | 10835 | -0.009 | -0.2808 | No | ||
107 | GJB3 | 2650040 | 10910 | -0.010 | -0.2846 | No | ||
108 | GPR150 | 2570440 | 10982 | -0.010 | -0.2881 | No | ||
109 | DSTN | 3140592 | 11054 | -0.010 | -0.2917 | No | ||
110 | SHC3 | 2690398 | 11057 | -0.010 | -0.2916 | No | ||
111 | KBTBD5 | 6350025 | 11146 | -0.011 | -0.2960 | No | ||
112 | DNM1 | 1660097 5340519 | 11361 | -0.012 | -0.3073 | No | ||
113 | BTK | 3130044 | 11612 | -0.013 | -0.3206 | No | ||
114 | PADI3 | 6520072 | 11660 | -0.013 | -0.3227 | No | ||
115 | PPP1R9B | 3130619 | 11732 | -0.014 | -0.3262 | No | ||
116 | ELK3 | 460377 1400762 3710497 | 12000 | -0.016 | -0.3403 | No | ||
117 | NRIP3 | 1340372 | 12035 | -0.016 | -0.3417 | No | ||
118 | HS3ST3B1 | 380040 | 12112 | -0.016 | -0.3454 | No | ||
119 | PTPRR | 130121 3990273 | 12200 | -0.017 | -0.3497 | No | ||
120 | TRIB1 | 2320435 | 12289 | -0.018 | -0.3540 | No | ||
121 | ESRRB | 3870082 | 12295 | -0.018 | -0.3537 | No | ||
122 | NEK6 | 3360687 | 12367 | -0.019 | -0.3571 | No | ||
123 | AK5 | 6290348 | 12555 | -0.020 | -0.3667 | No | ||
124 | BLMH | 1410438 | 12677 | -0.021 | -0.3727 | No | ||
125 | EEF1A2 | 2260162 5290086 | 12703 | -0.022 | -0.3735 | No | ||
126 | LAMC2 | 450692 2680041 4200059 4670148 | 12714 | -0.022 | -0.3734 | No | ||
127 | APOB48R | 2810070 | 13032 | -0.025 | -0.3900 | No | ||
128 | STAT5B | 6200026 | 13051 | -0.026 | -0.3902 | No | ||
129 | EPHA2 | 5890056 | 13132 | -0.027 | -0.3939 | No | ||
130 | GPR3 | 2970452 | 13186 | -0.027 | -0.3960 | No | ||
131 | UBE2C | 6130017 | 13458 | -0.031 | -0.4099 | No | ||
132 | PAPPA | 4230463 | 13641 | -0.034 | -0.4188 | No | ||
133 | DUSP13 | 6400152 | 13725 | -0.036 | -0.4224 | No | ||
134 | ABCB6 | 6350138 | 13824 | -0.038 | -0.4267 | No | ||
135 | GGN | 1410528 4210082 5290170 | 14054 | -0.042 | -0.4380 | No | ||
136 | RB1CC1 | 510494 7100072 | 14171 | -0.045 | -0.4431 | No | ||
137 | SFN | 6290301 7510608 | 14188 | -0.045 | -0.4427 | No | ||
138 | CYFIP1 | 5690082 | 14237 | -0.046 | -0.4441 | No | ||
139 | LTBP3 | 1190162 2650440 6520451 | 14374 | -0.050 | -0.4502 | No | ||
140 | NRAS | 6900577 | 14481 | -0.053 | -0.4545 | No | ||
141 | HSPB7 | 1190441 | 14484 | -0.053 | -0.4532 | No | ||
142 | MAP1A | 4920576 | 14569 | -0.056 | -0.4562 | No | ||
143 | DCTN2 | 540471 3780717 | 14598 | -0.057 | -0.4562 | No | ||
144 | ADORA2A | 1990687 | 14687 | -0.059 | -0.4594 | No | ||
145 | MDFI | 6200041 | 14728 | -0.061 | -0.4600 | No | ||
146 | ABHD2 | 4850504 6840010 | 14751 | -0.062 | -0.4595 | No | ||
147 | USP2 | 1190292 1240253 4850035 | 14758 | -0.062 | -0.4582 | No | ||
148 | EIF4E | 1580403 70133 6380215 | 14939 | -0.069 | -0.4661 | No | ||
149 | STOML2 | 1940487 | 15135 | -0.078 | -0.4746 | No | ||
150 | CLSTN3 | 2350685 | 15163 | -0.079 | -0.4740 | No | ||
151 | MMP9 | 580338 | 15215 | -0.082 | -0.4745 | No | ||
152 | IRAK1 | 4120593 | 15253 | -0.084 | -0.4743 | No | ||
153 | FHL3 | 1090369 2650017 | 15566 | -0.103 | -0.4885 | No | ||
154 | LAPTM5 | 5550372 | 15585 | -0.105 | -0.4867 | No | ||
155 | VDR | 130156 510438 | 15628 | -0.107 | -0.4861 | No | ||
156 | AXIN2 | 3850131 | 15666 | -0.110 | -0.4851 | No | ||
157 | MMP19 | 5080377 | 15768 | -0.118 | -0.4874 | No | ||
158 | SYTL1 | 510487 | 15953 | -0.136 | -0.4938 | No | ||
159 | IGFBP6 | 1580181 | 15993 | -0.140 | -0.4922 | No | ||
160 | HDAC3 | 4060072 | 16189 | -0.161 | -0.4985 | Yes | ||
161 | CAMKK1 | 6370324 | 16259 | -0.169 | -0.4977 | Yes | ||
162 | SCRN1 | 6040025 6580019 | 16314 | -0.177 | -0.4959 | Yes | ||
163 | VIM | 20431 | 16321 | -0.177 | -0.4915 | Yes | ||
164 | CAPNS1 | 3940113 | 16401 | -0.188 | -0.4908 | Yes | ||
165 | ISG20 | 1770750 | 16402 | -0.188 | -0.4857 | Yes | ||
166 | TNFRSF12A | 4810253 | 16448 | -0.193 | -0.4830 | Yes | ||
167 | USP3 | 2060332 | 16490 | -0.198 | -0.4799 | Yes | ||
168 | ROM1 | 3130685 | 16695 | -0.228 | -0.4849 | Yes | ||
169 | AP2A2 | 130082 | 16891 | -0.257 | -0.4886 | Yes | ||
170 | AKT1S1 | 1660048 | 17029 | -0.279 | -0.4886 | Yes | ||
171 | BACH1 | 290195 | 17038 | -0.281 | -0.4815 | Yes | ||
172 | CD151 | 1450592 3780309 | 17044 | -0.282 | -0.4742 | Yes | ||
173 | BAG2 | 2900324 | 17243 | -0.320 | -0.4764 | Yes | ||
174 | FKBP8 | 4060019 | 17643 | -0.412 | -0.4871 | Yes | ||
175 | TBC1D17 | 1780450 | 17726 | -0.437 | -0.4799 | Yes | ||
176 | GNGT2 | 540176 | 17754 | -0.447 | -0.4694 | Yes | ||
177 | TAGLN2 | 4560121 | 17977 | -0.534 | -0.4672 | Yes | ||
178 | LIMK1 | 5080064 | 18040 | -0.577 | -0.4551 | Yes | ||
179 | MAPK3 | 580161 4780035 | 18139 | -0.653 | -0.4430 | Yes | ||
180 | LMNA | 520471 1500075 3190167 4210020 | 18166 | -0.670 | -0.4265 | Yes | ||
181 | ELA1 | 3390167 | 18327 | -0.914 | -0.4107 | Yes | ||
182 | ARRDC4 | 2810019 | 18442 | -1.093 | -0.3877 | Yes | ||
183 | UBQLN1 | 110280 730376 2470133 6590594 | 18532 | -1.554 | -0.3510 | Yes | ||
184 | ETV5 | 110017 | 18562 | -1.975 | -0.2998 | Yes | ||
185 | TCF7 | 3800736 5390181 | 18602 | -3.219 | -0.2158 | Yes | ||
186 | RPL27A | 3130451 110195 6840494 | 18616 | -8.101 | -0.0000 | Yes |