Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_01 |
Enrichment Score (ES) | -0.50067747 |
Normalized Enrichment Score (NES) | -1.2966288 |
Nominal p-value | 0.033587787 |
FDR q-value | 0.85296553 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RNF34 | 3800332 4590717 5670138 | 137 | 1.062 | 0.0240 | No | ||
2 | PPP2CA | 3990113 | 361 | 0.725 | 0.0333 | No | ||
3 | LUC7L | 6040156 6110411 | 528 | 0.608 | 0.0423 | No | ||
4 | PSMD7 | 2030619 6220594 | 536 | 0.604 | 0.0598 | No | ||
5 | DLX1 | 360168 | 648 | 0.540 | 0.0697 | No | ||
6 | NEDD4L | 6380368 | 661 | 0.535 | 0.0849 | No | ||
7 | EEF1A1 | 1980193 1990195 4670735 | 693 | 0.517 | 0.0984 | No | ||
8 | ATP1B1 | 3130594 | 766 | 0.483 | 0.1088 | No | ||
9 | VAPA | 2480594 | 781 | 0.478 | 0.1222 | No | ||
10 | YWHAG | 3780341 | 966 | 0.409 | 0.1243 | No | ||
11 | PSMD12 | 730044 | 1085 | 0.365 | 0.1287 | No | ||
12 | RAB3D | 4210253 | 1097 | 0.359 | 0.1387 | No | ||
13 | RBBP7 | 430113 450450 2370309 | 1106 | 0.357 | 0.1488 | No | ||
14 | ICK | 1580746 3140021 | 1348 | 0.294 | 0.1444 | No | ||
15 | MECP2 | 1940450 | 1363 | 0.290 | 0.1522 | No | ||
16 | GTF2B | 6860685 | 1592 | 0.236 | 0.1468 | No | ||
17 | DTX2 | 4210041 7000008 | 1725 | 0.213 | 0.1460 | No | ||
18 | TGFBR2 | 1780711 1980537 6550398 | 1826 | 0.195 | 0.1463 | No | ||
19 | ABHD4 | 6760450 | 1856 | 0.188 | 0.1503 | No | ||
20 | APOBEC1 | 4610022 | 2070 | 0.157 | 0.1434 | No | ||
21 | ABI3 | 1740563 | 2107 | 0.151 | 0.1459 | No | ||
22 | COL27A1 | 1740390 | 2538 | 0.103 | 0.1256 | No | ||
23 | VCL | 4120487 | 2724 | 0.087 | 0.1181 | No | ||
24 | LRRFIP2 | 670575 730152 6590438 | 2736 | 0.086 | 0.1201 | No | ||
25 | SNX10 | 3800035 | 2939 | 0.072 | 0.1112 | No | ||
26 | MCART1 | 5270059 | 3049 | 0.065 | 0.1072 | No | ||
27 | HEPH | 2940176 3390040 6100195 6900575 7100170 | 3090 | 0.062 | 0.1069 | No | ||
28 | FBS1 | 2570520 | 3129 | 0.060 | 0.1066 | No | ||
29 | STX17 | 2260037 | 3149 | 0.059 | 0.1073 | No | ||
30 | SNCG | 3120725 | 3171 | 0.057 | 0.1078 | No | ||
31 | ULK1 | 6100315 | 3313 | 0.049 | 0.1017 | No | ||
32 | GADD45G | 2510142 | 3315 | 0.049 | 0.1031 | No | ||
33 | LY6D | 4050010 | 3381 | 0.047 | 0.1009 | No | ||
34 | LAMC1 | 4730025 | 3413 | 0.045 | 0.1006 | No | ||
35 | RIN1 | 510593 | 3517 | 0.041 | 0.0962 | No | ||
36 | BAZ2A | 730184 | 3525 | 0.041 | 0.0970 | No | ||
37 | NLK | 2030010 2450041 | 3545 | 0.040 | 0.0972 | No | ||
38 | DTNA | 1340600 1780731 2340278 2850132 | 3621 | 0.037 | 0.0942 | No | ||
39 | TRAF3 | 5690647 | 3649 | 0.036 | 0.0938 | No | ||
40 | GSTP1 | 3170102 3710707 5080368 | 3784 | 0.032 | 0.0875 | No | ||
41 | APBA2BP | 5700341 | 3818 | 0.031 | 0.0866 | No | ||
42 | LAMA3 | 1190131 5290239 | 3826 | 0.031 | 0.0871 | No | ||
43 | MAPK10 | 6110193 | 3860 | 0.030 | 0.0862 | No | ||
44 | SLC22A18 | 7050168 | 3910 | 0.029 | 0.0844 | No | ||
45 | SSH2 | 360056 | 4096 | 0.024 | 0.0751 | No | ||
46 | HCN3 | 3940438 6840750 | 4112 | 0.024 | 0.0750 | No | ||
47 | RPS20 | 1740092 | 4127 | 0.024 | 0.0749 | No | ||
48 | TNXB | 630592 3830020 5360497 7000673 | 4440 | 0.019 | 0.0586 | No | ||
49 | TIAL1 | 4150048 6510605 | 4834 | 0.014 | 0.0377 | No | ||
50 | PSMD11 | 2340538 6510053 | 5043 | 0.012 | 0.0267 | No | ||
51 | CDKN1A | 4050088 6400706 | 5145 | 0.011 | 0.0216 | No | ||
52 | OMG | 6760066 | 5146 | 0.011 | 0.0219 | No | ||
53 | IL6 | 380133 | 5316 | 0.010 | 0.0131 | No | ||
54 | KCNA2 | 5080403 | 5325 | 0.010 | 0.0129 | No | ||
55 | LRP1B | 1450193 | 5326 | 0.010 | 0.0132 | No | ||
56 | PFTK1 | 1780181 | 5521 | 0.009 | 0.0030 | No | ||
57 | CMAS | 2190129 | 5759 | 0.008 | -0.0097 | No | ||
58 | TAC1 | 7000195 380706 | 5783 | 0.007 | -0.0107 | No | ||
59 | P2RXL1 | 4730390 5220446 | 5798 | 0.007 | -0.0113 | No | ||
60 | ATP6V1C2 | 6620092 | 5834 | 0.007 | -0.0129 | No | ||
61 | LENEP | 4850369 | 5854 | 0.007 | -0.0138 | No | ||
62 | SNCB | 3360133 | 5942 | 0.007 | -0.0183 | No | ||
63 | GFAP | 2060092 | 6098 | 0.006 | -0.0265 | No | ||
64 | DHRS3 | 360609 | 6184 | 0.006 | -0.0310 | No | ||
65 | ABCF3 | 7100100 | 6191 | 0.006 | -0.0311 | No | ||
66 | IL11 | 1740398 | 6195 | 0.006 | -0.0311 | No | ||
67 | HS6ST2 | 520133 5550603 | 6323 | 0.005 | -0.0379 | No | ||
68 | FGF12 | 1740446 2360037 | 6946 | 0.003 | -0.0715 | No | ||
69 | ATP6V0D2 | 7050541 | 7087 | 0.002 | -0.0791 | No | ||
70 | PTPRN | 5900577 | 7449 | 0.001 | -0.0986 | No | ||
71 | ASB5 | 2760575 | 7509 | 0.001 | -0.1018 | No | ||
72 | USP13 | 1450670 | 7517 | 0.001 | -0.1021 | No | ||
73 | CALB2 | 6130170 6590368 | 7665 | 0.001 | -0.1101 | No | ||
74 | SERPINB5 | 6940050 | 7674 | 0.001 | -0.1105 | No | ||
75 | SPRED1 | 6940706 | 7965 | -0.000 | -0.1263 | No | ||
76 | AKT3 | 1580270 3290278 | 7974 | -0.000 | -0.1267 | No | ||
77 | SYT2 | 60609 | 8157 | -0.001 | -0.1365 | No | ||
78 | PLCD1 | 2030484 | 8480 | -0.002 | -0.1540 | No | ||
79 | MMP7 | 1780497 | 8489 | -0.002 | -0.1543 | No | ||
80 | RBP4 | 4540131 | 8528 | -0.002 | -0.1564 | No | ||
81 | PHLDA2 | 4810494 | 8570 | -0.002 | -0.1585 | No | ||
82 | IGSF9 | 1770411 | 8763 | -0.002 | -0.1689 | No | ||
83 | MYB | 1660494 5860451 6130706 | 8839 | -0.003 | -0.1729 | No | ||
84 | SFTPC | 3290133 | 8891 | -0.003 | -0.1755 | No | ||
85 | ANXA7 | 6110446 | 8963 | -0.003 | -0.1793 | No | ||
86 | OLR1 | 50025 3840484 | 9104 | -0.003 | -0.1868 | No | ||
87 | MAPRE3 | 7050504 | 9213 | -0.004 | -0.1926 | No | ||
88 | EYA1 | 1450278 5220390 | 9222 | -0.004 | -0.1929 | No | ||
89 | TRPV3 | 540341 | 9289 | -0.004 | -0.1963 | No | ||
90 | CPNE8 | 7040039 | 9458 | -0.004 | -0.2053 | No | ||
91 | FOSL1 | 430021 | 9620 | -0.005 | -0.2139 | No | ||
92 | SH3RF2 | 6200600 | 9656 | -0.005 | -0.2157 | No | ||
93 | EIF3S1 | 6130368 6770044 | 9725 | -0.005 | -0.2192 | No | ||
94 | ST18 | 5720537 | 10225 | -0.007 | -0.2461 | No | ||
95 | SCEL | 3190129 | 10252 | -0.007 | -0.2473 | No | ||
96 | BNIP3 | 3140270 | 10311 | -0.007 | -0.2502 | No | ||
97 | COL5A3 | 1940471 | 10316 | -0.007 | -0.2502 | No | ||
98 | TLL1 | 2680315 | 10397 | -0.008 | -0.2543 | No | ||
99 | CMYA1 | 6900632 | 10404 | -0.008 | -0.2544 | No | ||
100 | PSMA3 | 5900047 7040161 | 10426 | -0.008 | -0.2553 | No | ||
101 | PVALB | 5570450 | 10449 | -0.008 | -0.2563 | No | ||
102 | ANGPT1 | 3990368 5130288 6770035 | 10657 | -0.009 | -0.2673 | No | ||
103 | SLC26A1 | 2190142 | 10698 | -0.009 | -0.2692 | No | ||
104 | SV2B | 3850717 | 10799 | -0.009 | -0.2744 | No | ||
105 | IDS | 360619 5720161 | 10902 | -0.010 | -0.2796 | No | ||
106 | GDNF | 4050487 5720739 | 11018 | -0.010 | -0.2855 | No | ||
107 | SHC3 | 2690398 | 11057 | -0.010 | -0.2873 | No | ||
108 | SMPX | 6590440 | 11194 | -0.011 | -0.2944 | No | ||
109 | AQP5 | 3830451 | 11217 | -0.011 | -0.2952 | No | ||
110 | NUDT11 | 3840239 | 11238 | -0.011 | -0.2960 | No | ||
111 | SPATS2 | 2360066 | 11506 | -0.013 | -0.3101 | No | ||
112 | BTK | 3130044 | 11612 | -0.013 | -0.3154 | No | ||
113 | DIRAS1 | 2640270 | 11693 | -0.014 | -0.3193 | No | ||
114 | PPP1R9B | 3130619 | 11732 | -0.014 | -0.3210 | No | ||
115 | CHST4 | 1190008 | 11791 | -0.014 | -0.3237 | No | ||
116 | SLC35E4 | 2370711 | 11803 | -0.014 | -0.3239 | No | ||
117 | NRIP3 | 1340372 | 12035 | -0.016 | -0.3360 | No | ||
118 | FGF9 | 1050195 | 12113 | -0.016 | -0.3397 | No | ||
119 | PTPRR | 130121 3990273 | 12200 | -0.017 | -0.3438 | No | ||
120 | TRIB1 | 2320435 | 12289 | -0.018 | -0.3481 | No | ||
121 | DMD | 1740041 3990332 | 12328 | -0.018 | -0.3496 | No | ||
122 | NEK6 | 3360687 | 12367 | -0.019 | -0.3511 | No | ||
123 | MYOZ2 | 1050253 | 12503 | -0.020 | -0.3578 | No | ||
124 | MARK1 | 450484 | 12605 | -0.021 | -0.3627 | No | ||
125 | ELAVL2 | 360181 | 12702 | -0.022 | -0.3673 | No | ||
126 | EEF1A2 | 2260162 5290086 | 12703 | -0.022 | -0.3666 | No | ||
127 | IVL | 4560500 | 12717 | -0.022 | -0.3667 | No | ||
128 | ITGAX | 6130524 | 12722 | -0.022 | -0.3663 | No | ||
129 | UBXD3 | 5050193 | 12798 | -0.023 | -0.3697 | No | ||
130 | PPP2R5B | 2900441 | 12809 | -0.023 | -0.3695 | No | ||
131 | HSD3B7 | 1410129 | 13018 | -0.025 | -0.3801 | No | ||
132 | EPHA2 | 5890056 | 13132 | -0.027 | -0.3854 | No | ||
133 | CSF3 | 2230193 6660707 | 13421 | -0.031 | -0.4001 | No | ||
134 | DUSP13 | 6400152 | 13725 | -0.036 | -0.4155 | No | ||
135 | SYNGR1 | 5130452 6650056 | 13763 | -0.036 | -0.4165 | No | ||
136 | ABCB6 | 6350138 | 13824 | -0.038 | -0.4186 | No | ||
137 | MRGPRF | 4780746 | 14154 | -0.045 | -0.4351 | No | ||
138 | RB1CC1 | 510494 7100072 | 14171 | -0.045 | -0.4347 | No | ||
139 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14267 | -0.047 | -0.4385 | No | ||
140 | CSMD3 | 1660427 1940687 | 14291 | -0.047 | -0.4383 | No | ||
141 | MAPK12 | 450022 1340717 7050484 | 14503 | -0.054 | -0.4482 | No | ||
142 | DCTN2 | 540471 3780717 | 14598 | -0.057 | -0.4516 | No | ||
143 | SLC38A3 | 5340142 | 14653 | -0.059 | -0.4528 | No | ||
144 | COL7A1 | 1230168 2190072 | 14692 | -0.060 | -0.4531 | No | ||
145 | MDFI | 6200041 | 14728 | -0.061 | -0.4532 | No | ||
146 | MMRN2 | 1740047 | 14946 | -0.069 | -0.4629 | No | ||
147 | SERTAD1 | 2680332 | 14981 | -0.071 | -0.4627 | No | ||
148 | CCL27 | 2120070 | 14983 | -0.071 | -0.4606 | No | ||
149 | IRAK1 | 4120593 | 15253 | -0.084 | -0.4727 | No | ||
150 | DUSP14 | 1230358 | 15291 | -0.086 | -0.4722 | No | ||
151 | GADD45A | 2900717 | 15292 | -0.086 | -0.4696 | No | ||
152 | ADRA1A | 1230446 2260390 | 15314 | -0.088 | -0.4682 | No | ||
153 | CDH23 | 4250242 5290397 6550397 | 15379 | -0.091 | -0.4690 | No | ||
154 | WASF2 | 4850592 | 15474 | -0.098 | -0.4712 | No | ||
155 | VDR | 130156 510438 | 15628 | -0.107 | -0.4763 | No | ||
156 | TUBB4 | 5310681 | 15921 | -0.132 | -0.4882 | No | ||
157 | PIM1 | 630047 | 16020 | -0.143 | -0.4893 | No | ||
158 | HDAC3 | 4060072 | 16189 | -0.161 | -0.4937 | No | ||
159 | VAT1 | 1050040 | 16319 | -0.177 | -0.4954 | Yes | ||
160 | ABCA2 | 5050039 | 16320 | -0.177 | -0.4902 | Yes | ||
161 | VASP | 7050500 | 16429 | -0.191 | -0.4904 | Yes | ||
162 | TNFRSF12A | 4810253 | 16448 | -0.193 | -0.4857 | Yes | ||
163 | CLIC1 | 110600 | 16455 | -0.194 | -0.4803 | Yes | ||
164 | ABCD1 | 5670373 | 16525 | -0.203 | -0.4780 | Yes | ||
165 | EMP3 | 1500722 1570039 | 16574 | -0.210 | -0.4744 | Yes | ||
166 | ROM1 | 3130685 | 16695 | -0.228 | -0.4742 | Yes | ||
167 | HSPB8 | 540563 | 16768 | -0.238 | -0.4711 | Yes | ||
168 | ADCK4 | 1660180 | 16821 | -0.247 | -0.4666 | Yes | ||
169 | PEA15 | 4590685 | 17036 | -0.281 | -0.4699 | Yes | ||
170 | TBXAS1 | 5050053 6900286 | 17037 | -0.281 | -0.4616 | Yes | ||
171 | BACH1 | 290195 | 17038 | -0.281 | -0.4533 | Yes | ||
172 | BAG2 | 2900324 | 17243 | -0.320 | -0.4549 | Yes | ||
173 | GABARAPL1 | 2810458 | 17321 | -0.336 | -0.4492 | Yes | ||
174 | RIT1 | 5390338 | 17404 | -0.352 | -0.4432 | Yes | ||
175 | PSMD2 | 4670706 5050364 | 17432 | -0.356 | -0.4342 | Yes | ||
176 | GPSM3 | 2690154 | 17435 | -0.356 | -0.4237 | Yes | ||
177 | SQSTM1 | 6550056 | 17591 | -0.393 | -0.4205 | Yes | ||
178 | GNGT2 | 540176 | 17754 | -0.447 | -0.4161 | Yes | ||
179 | ALS2CR2 | 6450128 7100092 | 17807 | -0.464 | -0.4052 | Yes | ||
180 | ALDOA | 6290672 | 17837 | -0.478 | -0.3927 | Yes | ||
181 | TAGLN2 | 4560121 | 17977 | -0.534 | -0.3845 | Yes | ||
182 | POLD4 | 2320082 | 18150 | -0.660 | -0.3743 | Yes | ||
183 | LMNA | 520471 1500075 3190167 4210020 | 18166 | -0.670 | -0.3553 | Yes | ||
184 | PADI4 | 1740075 4810441 | 18412 | -1.039 | -0.3379 | Yes | ||
185 | SLC38A2 | 1470242 3800026 | 18436 | -1.086 | -0.3070 | Yes | ||
186 | ARHGAP8 | 380333 5390487 | 18468 | -1.174 | -0.2740 | Yes | ||
187 | ENO1 | 5340128 | 18526 | -1.526 | -0.2320 | Yes | ||
188 | NCDN | 50040 1980739 3520603 | 18539 | -1.599 | -0.1853 | Yes | ||
189 | SLC11A1 | 940286 2810435 6370647 | 18601 | -3.189 | -0.0944 | Yes | ||
190 | TCF7 | 3800736 5390181 | 18602 | -3.219 | 0.0008 | Yes |