Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | CAGTGTT,MIR-141,MIR-200A |
Enrichment Score (ES) | 0.6457999 |
Normalized Enrichment Score (NES) | 1.8259981 |
Nominal p-value | 0.0 |
FDR q-value | 0.003503829 |
FWER p-Value | 0.0060 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ATP2A2 | 1090075 3990279 | 62 | 1.475 | 0.0326 | Yes | ||
2 | TULP4 | 2320364 | 67 | 1.415 | 0.0670 | Yes | ||
3 | BRD3 | 6130672 | 90 | 1.239 | 0.0960 | Yes | ||
4 | DOLPP1 | 4780619 6400053 | 99 | 1.172 | 0.1242 | Yes | ||
5 | CUL3 | 1850520 | 102 | 1.160 | 0.1524 | Yes | ||
6 | TFRC | 4050551 | 126 | 1.089 | 0.1777 | Yes | ||
7 | PRKACB | 4210170 | 143 | 1.046 | 0.2024 | Yes | ||
8 | HOXB4 | 540131 | 207 | 0.901 | 0.2209 | Yes | ||
9 | TCF12 | 3610324 7000156 | 219 | 0.880 | 0.2418 | Yes | ||
10 | ANP32E | 6510706 | 223 | 0.876 | 0.2630 | Yes | ||
11 | RABGAP1 | 5050397 | 232 | 0.869 | 0.2838 | Yes | ||
12 | MBNL1 | 2640762 7100048 | 235 | 0.865 | 0.3048 | Yes | ||
13 | PDCD4 | 3360403 5690110 | 246 | 0.850 | 0.3250 | Yes | ||
14 | SFPQ | 4760110 | 276 | 0.806 | 0.3431 | Yes | ||
15 | RAP2C | 1690132 | 282 | 0.799 | 0.3623 | Yes | ||
16 | PITPNB | 5130039 | 341 | 0.747 | 0.3774 | Yes | ||
17 | PPP2CA | 3990113 | 361 | 0.725 | 0.3941 | Yes | ||
18 | CD47 | 1850603 | 378 | 0.703 | 0.4104 | Yes | ||
19 | WSB1 | 870563 | 406 | 0.681 | 0.4255 | Yes | ||
20 | OGT | 2360131 4610333 | 449 | 0.653 | 0.4392 | Yes | ||
21 | TRAM1 | 2340441 6620592 | 452 | 0.652 | 0.4550 | Yes | ||
22 | APRIN | 2810050 | 453 | 0.652 | 0.4709 | Yes | ||
23 | MTPN | 3940167 | 514 | 0.614 | 0.4826 | Yes | ||
24 | CDV3 | 1940577 | 563 | 0.586 | 0.4943 | Yes | ||
25 | SUPT6H | 3170082 | 591 | 0.568 | 0.5067 | Yes | ||
26 | RUNX1 | 3840711 | 602 | 0.563 | 0.5199 | Yes | ||
27 | ATP6V1A | 6590242 | 739 | 0.493 | 0.5245 | Yes | ||
28 | ATP1B1 | 3130594 | 766 | 0.483 | 0.5349 | Yes | ||
29 | OSBPL11 | 1770044 | 794 | 0.475 | 0.5450 | Yes | ||
30 | RNF44 | 5910692 | 822 | 0.461 | 0.5548 | Yes | ||
31 | MAP2K4 | 5130133 | 854 | 0.449 | 0.5641 | Yes | ||
32 | YWHAG | 3780341 | 966 | 0.409 | 0.5680 | Yes | ||
33 | CSNK1G3 | 110450 | 1086 | 0.364 | 0.5705 | Yes | ||
34 | PPP1R15B | 2640280 5860082 | 1207 | 0.333 | 0.5721 | Yes | ||
35 | H2AFZ | 1470168 | 1209 | 0.332 | 0.5801 | Yes | ||
36 | CCNE2 | 3120537 | 1281 | 0.315 | 0.5839 | Yes | ||
37 | FKBP5 | 2190048 | 1282 | 0.315 | 0.5916 | Yes | ||
38 | PLAGL2 | 1770148 | 1306 | 0.305 | 0.5978 | Yes | ||
39 | MECP2 | 1940450 | 1363 | 0.290 | 0.6018 | Yes | ||
40 | YTHDF2 | 4060332 4610279 | 1429 | 0.271 | 0.6049 | Yes | ||
41 | RBMS1 | 6400014 | 1477 | 0.261 | 0.6087 | Yes | ||
42 | ANKFY1 | 360309 5390021 | 1500 | 0.256 | 0.6138 | Yes | ||
43 | SLC20A1 | 6420014 | 1538 | 0.248 | 0.6178 | Yes | ||
44 | SLC23A2 | 6660722 | 1550 | 0.245 | 0.6232 | Yes | ||
45 | ATP6V1B2 | 4060528 | 1598 | 0.234 | 0.6264 | Yes | ||
46 | MIB1 | 3800537 | 1697 | 0.217 | 0.6263 | Yes | ||
47 | SIRT1 | 1190731 | 1727 | 0.212 | 0.6299 | Yes | ||
48 | ARNTL | 3170463 | 1753 | 0.209 | 0.6337 | Yes | ||
49 | DNAJC13 | 4730091 | 1846 | 0.190 | 0.6333 | Yes | ||
50 | CDC14A | 4050132 | 2011 | 0.167 | 0.6285 | Yes | ||
51 | SIPA1L2 | 4850731 | 2031 | 0.163 | 0.6314 | Yes | ||
52 | ARHGEF18 | 2120279 | 2102 | 0.152 | 0.6313 | Yes | ||
53 | RTF1 | 2100735 | 2164 | 0.143 | 0.6315 | Yes | ||
54 | YAF2 | 940053 | 2175 | 0.141 | 0.6344 | Yes | ||
55 | STAT4 | 1660373 3130019 | 2200 | 0.138 | 0.6365 | Yes | ||
56 | KIF3A | 5050348 6650079 | 2244 | 0.133 | 0.6374 | Yes | ||
57 | SLC6A9 | 2470520 | 2289 | 0.128 | 0.6381 | Yes | ||
58 | GRB2 | 6650398 | 2342 | 0.122 | 0.6383 | Yes | ||
59 | BACE1 | 2650438 | 2346 | 0.122 | 0.6411 | Yes | ||
60 | AK3L1 | 7100601 | 2356 | 0.120 | 0.6435 | Yes | ||
61 | WDR44 | 130195 1050609 1570685 | 2479 | 0.108 | 0.6395 | Yes | ||
62 | CDC25A | 3800184 | 2485 | 0.107 | 0.6418 | Yes | ||
63 | MYH10 | 2640673 | 2489 | 0.107 | 0.6443 | Yes | ||
64 | FOXP1 | 6510433 | 2509 | 0.105 | 0.6458 | Yes | ||
65 | UBE3A | 1240152 2690438 5860609 | 2830 | 0.080 | 0.6303 | No | ||
66 | FUS | 4760619 | 2833 | 0.079 | 0.6322 | No | ||
67 | SLC25A3 | 670112 | 2850 | 0.079 | 0.6332 | No | ||
68 | MOBKL2B | 940128 | 2856 | 0.078 | 0.6349 | No | ||
69 | YTHDF3 | 4540632 4670717 7040609 | 2929 | 0.073 | 0.6327 | No | ||
70 | ATF5 | 5670685 | 3035 | 0.066 | 0.6286 | No | ||
71 | MARCH7 | 3800020 6620168 | 3128 | 0.060 | 0.6251 | No | ||
72 | PTGES3 | 2190440 2680524 | 3191 | 0.056 | 0.6230 | No | ||
73 | SPAG9 | 580497 2510180 4210685 | 3200 | 0.055 | 0.6240 | No | ||
74 | BAP1 | 3830131 | 3225 | 0.054 | 0.6240 | No | ||
75 | BICD2 | 1090411 | 3249 | 0.053 | 0.6240 | No | ||
76 | CHD9 | 430037 2570129 5420398 | 3360 | 0.048 | 0.6192 | No | ||
77 | FBXL2 | 6450722 | 3374 | 0.047 | 0.6196 | No | ||
78 | CALU | 2680403 3520056 4610348 5720176 6130121 | 3471 | 0.043 | 0.6155 | No | ||
79 | GATA6 | 1770010 | 3530 | 0.041 | 0.6133 | No | ||
80 | TNS3 | 6380242 | 3622 | 0.037 | 0.6092 | No | ||
81 | CBL | 6380068 | 3650 | 0.036 | 0.6087 | No | ||
82 | TTR | 4150072 | 3665 | 0.035 | 0.6088 | No | ||
83 | SLC39A9 | 3940348 | 3756 | 0.033 | 0.6047 | No | ||
84 | OLIG3 | 1050603 | 3880 | 0.030 | 0.5987 | No | ||
85 | PBEF1 | 1090278 | 3903 | 0.029 | 0.5982 | No | ||
86 | SEPT7 | 2760685 | 3972 | 0.027 | 0.5952 | No | ||
87 | QKI | 5220093 6130044 | 4130 | 0.024 | 0.5872 | No | ||
88 | DDX5 | 940021 2630338 3440148 | 4145 | 0.023 | 0.5870 | No | ||
89 | KPNA3 | 7040088 | 4148 | 0.023 | 0.5875 | No | ||
90 | THRAP2 | 4920600 | 4187 | 0.023 | 0.5860 | No | ||
91 | HMG20A | 4590113 | 4313 | 0.021 | 0.5797 | No | ||
92 | OLFM1 | 3360161 5570066 | 4362 | 0.020 | 0.5776 | No | ||
93 | NFASC | 1940619 2470156 4590168 6840524 | 4372 | 0.020 | 0.5776 | No | ||
94 | CSNK2A1 | 1580577 | 4373 | 0.020 | 0.5780 | No | ||
95 | PHLPP | 3440563 | 4399 | 0.019 | 0.5772 | No | ||
96 | STXBP1 | 360072 6220717 | 4526 | 0.018 | 0.5707 | No | ||
97 | NRXN1 | 460408 5340270 6370066 | 4544 | 0.017 | 0.5702 | No | ||
98 | RTN4RL1 | 2630368 | 4608 | 0.017 | 0.5672 | No | ||
99 | PCTK2 | 5700673 | 4623 | 0.016 | 0.5669 | No | ||
100 | RPH3AL | 70110 | 4626 | 0.016 | 0.5672 | No | ||
101 | KCNJ2 | 630019 | 4662 | 0.016 | 0.5656 | No | ||
102 | E2F3 | 50162 460180 | 4775 | 0.015 | 0.5599 | No | ||
103 | TIAL1 | 4150048 6510605 | 4834 | 0.014 | 0.5571 | No | ||
104 | RAD23B | 2190671 | 4843 | 0.014 | 0.5570 | No | ||
105 | HIPK1 | 110193 | 4952 | 0.013 | 0.5515 | No | ||
106 | FGFR2 | 4670601 5570402 6940377 | 5108 | 0.012 | 0.5433 | No | ||
107 | TCERG1 | 2350551 4540397 5220746 | 5359 | 0.010 | 0.5300 | No | ||
108 | ARPC5 | 1740411 3450300 | 5364 | 0.010 | 0.5300 | No | ||
109 | EXOC5 | 7000711 | 5439 | 0.009 | 0.5262 | No | ||
110 | PTP4A1 | 130692 | 5470 | 0.009 | 0.5248 | No | ||
111 | TSC1 | 1850672 | 5606 | 0.008 | 0.5177 | No | ||
112 | HOXC13 | 4070722 | 5895 | 0.007 | 0.5022 | No | ||
113 | SOX11 | 610279 | 5967 | 0.007 | 0.4985 | No | ||
114 | RARB | 430139 1410138 | 6021 | 0.006 | 0.4957 | No | ||
115 | MTSS1 | 780435 2370114 | 6065 | 0.006 | 0.4935 | No | ||
116 | MYRIP | 1580471 | 6149 | 0.006 | 0.4892 | No | ||
117 | THRB | 1780673 | 6253 | 0.005 | 0.4837 | No | ||
118 | SRC | 580132 | 6258 | 0.005 | 0.4836 | No | ||
119 | NRP2 | 4070400 5860041 6650446 | 6316 | 0.005 | 0.4806 | No | ||
120 | SNAP91 | 3170056 5690520 | 6416 | 0.005 | 0.4754 | No | ||
121 | PHYHIPL | 2360706 3840692 | 6547 | 0.004 | 0.4684 | No | ||
122 | CXCL12 | 580546 4150750 4570068 | 6726 | 0.003 | 0.4588 | No | ||
123 | ATXN7 | 1450435 | 6868 | 0.003 | 0.4512 | No | ||
124 | PLAG1 | 1450142 3870139 6520039 | 6908 | 0.003 | 0.4492 | No | ||
125 | DR1 | 5860750 | 6914 | 0.003 | 0.4490 | No | ||
126 | TRHDE | 1690068 | 7134 | 0.002 | 0.4371 | No | ||
127 | CLASP2 | 2510139 | 7206 | 0.002 | 0.4333 | No | ||
128 | DUSP3 | 1240129 6840215 | 7221 | 0.002 | 0.4326 | No | ||
129 | MMP16 | 2680139 | 7380 | 0.001 | 0.4240 | No | ||
130 | PITX2 | 870537 2690139 | 7394 | 0.001 | 0.4234 | No | ||
131 | KHDRBS2 | 3520717 | 7537 | 0.001 | 0.4157 | No | ||
132 | MYT1L | 5670369 6660403 | 7568 | 0.001 | 0.4140 | No | ||
133 | SLC16A7 | 2320672 | 7610 | 0.001 | 0.4118 | No | ||
134 | SLC1A1 | 520372 6420059 | 7651 | 0.001 | 0.4097 | No | ||
135 | HNRPF | 670138 | 7678 | 0.001 | 0.4083 | No | ||
136 | PCDH8 | 2360047 4200452 | 8098 | -0.001 | 0.3855 | No | ||
137 | NR2C2 | 6100097 | 8221 | -0.001 | 0.3789 | No | ||
138 | SPG3A | 2760091 3120170 | 8335 | -0.001 | 0.3728 | No | ||
139 | PAFAH1B2 | 5360546 6860672 | 8395 | -0.001 | 0.3696 | No | ||
140 | SP4 | 3850176 | 8548 | -0.002 | 0.3614 | No | ||
141 | DIXDC1 | 6980435 | 8564 | -0.002 | 0.3606 | No | ||
142 | LENG8 | 3130731 | 8602 | -0.002 | 0.3587 | No | ||
143 | ESRRG | 4010181 | 8681 | -0.002 | 0.3545 | No | ||
144 | ITSN1 | 2640577 | 9086 | -0.003 | 0.3326 | No | ||
145 | ZCCHC3 | 580438 1990035 4780278 | 9201 | -0.004 | 0.3265 | No | ||
146 | CHES1 | 4570121 5700162 | 9265 | -0.004 | 0.3232 | No | ||
147 | STK35 | 2360121 | 9303 | -0.004 | 0.3212 | No | ||
148 | GRIN3A | 2370592 | 9413 | -0.004 | 0.3154 | No | ||
149 | ACVR2A | 6110647 | 9461 | -0.004 | 0.3130 | No | ||
150 | GPM6B | 6220458 | 9482 | -0.005 | 0.3120 | No | ||
151 | ZFR | 5910647 | 9514 | -0.005 | 0.3104 | No | ||
152 | CSNK1A1 | 2340427 | 9666 | -0.005 | 0.3023 | No | ||
153 | EPHA7 | 1190288 4010278 | 9702 | -0.005 | 0.3006 | No | ||
154 | HOXA11 | 6980133 | 9741 | -0.005 | 0.2986 | No | ||
155 | LHX6 | 2360731 3360397 | 9956 | -0.006 | 0.2871 | No | ||
156 | WDFY3 | 3610041 4560333 4570273 | 9963 | -0.006 | 0.2870 | No | ||
157 | RBM7 | 5890348 | 9977 | -0.006 | 0.2864 | No | ||
158 | PCDH9 | 2100136 | 10213 | -0.007 | 0.2738 | No | ||
159 | LPP | 1660541 | 10447 | -0.008 | 0.2613 | No | ||
160 | B3GNT1 | 2350446 | 10453 | -0.008 | 0.2612 | No | ||
161 | SNF1LK | 6110403 | 10547 | -0.008 | 0.2564 | No | ||
162 | HLF | 2370113 | 10610 | -0.008 | 0.2532 | No | ||
163 | APBB2 | 5130403 | 10666 | -0.009 | 0.2504 | No | ||
164 | CALCR | 1690494 | 10794 | -0.009 | 0.2438 | No | ||
165 | TMEFF1 | 2680100 | 10841 | -0.009 | 0.2415 | No | ||
166 | FOXA1 | 3710609 | 10870 | -0.009 | 0.2402 | No | ||
167 | WDR26 | 1090138 | 10896 | -0.010 | 0.2391 | No | ||
168 | LYPLA1 | 4480373 5570551 | 10908 | -0.010 | 0.2387 | No | ||
169 | SEMA6A | 2690138 3060021 | 11066 | -0.010 | 0.2304 | No | ||
170 | DRD2 | 5890369 | 11083 | -0.010 | 0.2298 | No | ||
171 | TTYH2 | 1450397 3870100 6550347 | 11093 | -0.011 | 0.2296 | No | ||
172 | SLC17A6 | 4210576 | 11697 | -0.014 | 0.1971 | No | ||
173 | TM9SF4 | 450538 1050093 4210112 | 11733 | -0.014 | 0.1956 | No | ||
174 | TGFB2 | 4920292 | 11832 | -0.015 | 0.1906 | No | ||
175 | CNR1 | 6550494 6760497 | 11943 | -0.015 | 0.1850 | No | ||
176 | PTPRG | 2650524 1340022 | 11948 | -0.015 | 0.1851 | No | ||
177 | BRUNOL6 | 6840373 | 12084 | -0.016 | 0.1782 | No | ||
178 | HOXB5 | 2900538 | 12212 | -0.017 | 0.1717 | No | ||
179 | ELF2 | 1690014 2480132 3060180 3190504 | 12215 | -0.017 | 0.1720 | No | ||
180 | POU4F1 | 2260315 | 12336 | -0.018 | 0.1659 | No | ||
181 | JUN | 840170 | 12454 | -0.019 | 0.1600 | No | ||
182 | PPP2R2A | 2900014 5700575 | 12489 | -0.020 | 0.1587 | No | ||
183 | USP9X | 130435 2370735 3120338 | 12651 | -0.021 | 0.1504 | No | ||
184 | ELAVL2 | 360181 | 12702 | -0.022 | 0.1482 | No | ||
185 | CPD | 5360403 5860685 | 12752 | -0.022 | 0.1461 | No | ||
186 | LRRC8A | 2510193 | 12823 | -0.023 | 0.1429 | No | ||
187 | KLHL18 | 4560075 | 12848 | -0.023 | 0.1421 | No | ||
188 | STRN | 5570706 7050333 | 12967 | -0.025 | 0.1363 | No | ||
189 | STAT5B | 6200026 | 13051 | -0.026 | 0.1324 | No | ||
190 | EPHA2 | 5890056 | 13132 | -0.027 | 0.1287 | No | ||
191 | CNP | 2260451 | 13326 | -0.029 | 0.1190 | No | ||
192 | RAB38 | 2970735 | 13354 | -0.030 | 0.1182 | No | ||
193 | SIM2 | 2100044 | 13412 | -0.031 | 0.1159 | No | ||
194 | CSF3 | 2230193 6660707 | 13421 | -0.031 | 0.1162 | No | ||
195 | GPC2 | 130647 | 13512 | -0.032 | 0.1121 | No | ||
196 | CYP26B1 | 2630142 | 13545 | -0.033 | 0.1111 | No | ||
197 | PAPPA | 4230463 | 13641 | -0.034 | 0.1068 | No | ||
198 | SOX5 | 2370576 2900167 3190128 5050528 | 14189 | -0.045 | 0.0782 | No | ||
199 | MDGA1 | 1170139 | 14197 | -0.046 | 0.0789 | No | ||
200 | PPT2 | 2340059 3450148 | 14524 | -0.055 | 0.0625 | No | ||
201 | KIF1C | 2480484 | 14528 | -0.055 | 0.0637 | No | ||
202 | ATXN1 | 5550156 | 14909 | -0.068 | 0.0447 | No | ||
203 | PEX5 | 1240746 1570092 2510487 | 14926 | -0.069 | 0.0455 | No | ||
204 | SPRYD3 | 50403 | 14948 | -0.069 | 0.0460 | No | ||
205 | SYT4 | 5080193 | 15095 | -0.076 | 0.0399 | No | ||
206 | DLC1 | 1090632 6450594 | 15335 | -0.089 | 0.0291 | No | ||
207 | TAF12 | 3710746 4920300 6180603 | 15395 | -0.092 | 0.0282 | No | ||
208 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 15440 | -0.096 | 0.0281 | No | ||
209 | DEK | 1050451 4560037 | 15792 | -0.121 | 0.0120 | No | ||
210 | FRMD4A | 2190176 | 15841 | -0.126 | 0.0125 | No | ||
211 | AMPD2 | 630093 1170070 | 15885 | -0.129 | 0.0133 | No | ||
212 | ACACA | 2490612 2680369 | 16012 | -0.142 | 0.0099 | No | ||
213 | SON | 3120148 5860239 7040403 | 16165 | -0.158 | 0.0055 | No | ||
214 | TOP1 | 770471 4060632 6650324 | 16196 | -0.162 | 0.0078 | No | ||
215 | HIC2 | 4010433 | 16357 | -0.182 | 0.0035 | No | ||
216 | EPN1 | 4060725 | 16509 | -0.201 | 0.0002 | No | ||
217 | SERF2 | 5720010 | 16654 | -0.220 | -0.0022 | No | ||
218 | STAT5A | 2680458 | 16710 | -0.230 | 0.0004 | No | ||
219 | ST3GAL3 | 2810601 | 16905 | -0.259 | -0.0038 | No | ||
220 | BHLHB2 | 7040603 | 16979 | -0.269 | -0.0012 | No | ||
221 | CDC42BPB | 6350037 | 17056 | -0.284 | 0.0016 | No | ||
222 | DMWD | 770019 1690047 | 17778 | -0.456 | -0.0265 | No | ||
223 | PSEN1 | 130403 2030647 6100603 | 18284 | -0.837 | -0.0335 | No | ||
224 | ACOT7 | 730735 1400176 7050053 | 18404 | -1.019 | -0.0151 | No | ||
225 | HRBL | 1850102 3830253 4780176 | 18439 | -1.090 | 0.0096 | No |