Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | CAGCTTT,MIR-320 |
Enrichment Score (ES) | 0.6013577 |
Normalized Enrichment Score (NES) | 1.6394696 |
Nominal p-value | 0.0 |
FDR q-value | 0.031294085 |
FWER p-Value | 0.27 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TPM3 | 670600 3170296 5670167 6650471 | 2 | 4.583 | 0.1422 | Yes | ||
2 | CNOT7 | 2450338 5720397 | 23 | 1.857 | 0.1988 | Yes | ||
3 | TFRC | 4050551 | 126 | 1.089 | 0.2270 | Yes | ||
4 | CUTL1 | 1570113 1770091 1850273 2100286 5340605 | 168 | 0.967 | 0.2548 | Yes | ||
5 | DHX15 | 870632 | 177 | 0.952 | 0.2840 | Yes | ||
6 | MCL1 | 1660672 | 184 | 0.934 | 0.3127 | Yes | ||
7 | HOXB4 | 540131 | 207 | 0.901 | 0.3394 | Yes | ||
8 | RAP2C | 1690132 | 282 | 0.799 | 0.3603 | Yes | ||
9 | RASA1 | 1240315 | 319 | 0.769 | 0.3822 | Yes | ||
10 | COPS2 | 3060142 | 351 | 0.735 | 0.4033 | Yes | ||
11 | GSPT1 | 5420050 | 396 | 0.689 | 0.4223 | Yes | ||
12 | ARPP-19 | 5700025 | 447 | 0.654 | 0.4399 | Yes | ||
13 | OGT | 2360131 4610333 | 449 | 0.653 | 0.4601 | Yes | ||
14 | RUNX1 | 3840711 | 602 | 0.563 | 0.4694 | Yes | ||
15 | KLF13 | 4670563 | 625 | 0.551 | 0.4853 | Yes | ||
16 | ATP6V1A | 6590242 | 739 | 0.493 | 0.4945 | Yes | ||
17 | USP20 | 520128 | 747 | 0.489 | 0.5093 | Yes | ||
18 | TPD52L2 | 6590040 | 946 | 0.416 | 0.5115 | Yes | ||
19 | UBE2D3 | 3190452 | 1032 | 0.381 | 0.5187 | Yes | ||
20 | ARL8B | 3710368 | 1052 | 0.373 | 0.5292 | Yes | ||
21 | SFRS7 | 2760408 | 1120 | 0.354 | 0.5366 | Yes | ||
22 | HNRPC | 1570133 3610131 | 1250 | 0.323 | 0.5396 | Yes | ||
23 | POLE4 | 6860097 | 1271 | 0.317 | 0.5484 | Yes | ||
24 | PPM1A | 1170301 5900273 | 1276 | 0.317 | 0.5580 | Yes | ||
25 | TLK2 | 1170161 | 1288 | 0.312 | 0.5671 | Yes | ||
26 | MECP2 | 1940450 | 1363 | 0.290 | 0.5721 | Yes | ||
27 | TOMM70A | 780114 | 1368 | 0.287 | 0.5808 | Yes | ||
28 | SEP15 | 1780451 2060450 5890451 | 1385 | 0.283 | 0.5887 | Yes | ||
29 | DHX30 | 2480494 | 1557 | 0.244 | 0.5870 | Yes | ||
30 | MAT2A | 4070026 4730079 6020280 | 1597 | 0.235 | 0.5922 | Yes | ||
31 | SUHW3 | 50400 | 1705 | 0.216 | 0.5931 | Yes | ||
32 | PPP1R16B | 3520300 | 1730 | 0.212 | 0.5984 | Yes | ||
33 | RAD18 | 5670372 | 1869 | 0.186 | 0.5967 | Yes | ||
34 | YWHAZ | 1230717 | 2155 | 0.145 | 0.5857 | Yes | ||
35 | PURB | 5360138 | 2214 | 0.136 | 0.5868 | Yes | ||
36 | MAPK8IP3 | 1660112 2060427 | 2219 | 0.136 | 0.5908 | Yes | ||
37 | DAG1 | 460053 610341 | 2316 | 0.125 | 0.5895 | Yes | ||
38 | AIM1 | 2810142 | 2338 | 0.122 | 0.5921 | Yes | ||
39 | GRB2 | 6650398 | 2342 | 0.122 | 0.5957 | Yes | ||
40 | YWHAQ | 6760524 | 2442 | 0.112 | 0.5938 | Yes | ||
41 | MAPK1 | 3190193 6200253 | 2463 | 0.109 | 0.5962 | Yes | ||
42 | PCDHA7 | 1850019 | 2477 | 0.108 | 0.5988 | Yes | ||
43 | DAZAP1 | 5890563 | 2492 | 0.106 | 0.6014 | Yes | ||
44 | CALM3 | 3390288 | 2554 | 0.101 | 0.6012 | No | ||
45 | GABPB2 | 6130450 7050735 | 2652 | 0.093 | 0.5988 | No | ||
46 | CPEB1 | 3190524 | 2660 | 0.092 | 0.6013 | No | ||
47 | STAG2 | 4540132 | 2779 | 0.084 | 0.5975 | No | ||
48 | SMAP1 | 840056 2360523 | 2845 | 0.079 | 0.5964 | No | ||
49 | YTHDF3 | 4540632 4670717 7040609 | 2929 | 0.073 | 0.5942 | No | ||
50 | ULK1 | 6100315 | 3313 | 0.049 | 0.5750 | No | ||
51 | LUC7L2 | 1850402 6350088 | 3453 | 0.044 | 0.5688 | No | ||
52 | AP3M1 | 5340433 | 3573 | 0.039 | 0.5636 | No | ||
53 | CLASP1 | 6860279 | 3615 | 0.037 | 0.5625 | No | ||
54 | DTNA | 1340600 1780731 2340278 2850132 | 3621 | 0.037 | 0.5634 | No | ||
55 | YWHAE | 5310435 | 3837 | 0.030 | 0.5527 | No | ||
56 | SDHC | 3140347 6100156 | 3969 | 0.027 | 0.5464 | No | ||
57 | ICA1 | 3830059 | 3973 | 0.027 | 0.5471 | No | ||
58 | SLITRK3 | 5910041 | 3975 | 0.027 | 0.5479 | No | ||
59 | ZNF3 | 1770193 2320047 2570273 | 4068 | 0.025 | 0.5437 | No | ||
60 | QKI | 5220093 6130044 | 4130 | 0.024 | 0.5411 | No | ||
61 | MLLT3 | 510204 3850722 6200088 | 4152 | 0.023 | 0.5407 | No | ||
62 | DNER | 3610170 | 4274 | 0.021 | 0.5348 | No | ||
63 | TMEM2 | 1980037 3290020 | 4351 | 0.020 | 0.5313 | No | ||
64 | NONO | 7050014 | 4395 | 0.019 | 0.5296 | No | ||
65 | SPRED2 | 510138 540195 | 4430 | 0.019 | 0.5283 | No | ||
66 | PALM2 | 4120068 7100398 | 4449 | 0.019 | 0.5279 | No | ||
67 | RHOBTB1 | 1410010 | 4528 | 0.018 | 0.5242 | No | ||
68 | MSI2 | 1190066 5270039 | 4558 | 0.017 | 0.5232 | No | ||
69 | PPARGC1A | 4670040 | 4653 | 0.016 | 0.5186 | No | ||
70 | PBX3 | 1300424 3710577 6180575 | 4765 | 0.015 | 0.5130 | No | ||
71 | AZIN1 | 3450070 | 4845 | 0.014 | 0.5092 | No | ||
72 | LRCH2 | 2900162 | 4878 | 0.014 | 0.5079 | No | ||
73 | FOXQ1 | 4850088 | 4921 | 0.013 | 0.5060 | No | ||
74 | PCDHA1 | 940026 540484 | 4928 | 0.013 | 0.5061 | No | ||
75 | HIPK1 | 110193 | 4952 | 0.013 | 0.5052 | No | ||
76 | PHF8 | 70722 | 4986 | 0.013 | 0.5039 | No | ||
77 | DSCAM | 1780050 2450731 2810438 | 5269 | 0.011 | 0.4889 | No | ||
78 | ARPC5 | 1740411 3450300 | 5364 | 0.010 | 0.4841 | No | ||
79 | ING5 | 3830440 5910239 6200471 6650576 | 5497 | 0.009 | 0.4772 | No | ||
80 | NEGR1 | 1940731 5130170 | 5509 | 0.009 | 0.4769 | No | ||
81 | TSC1 | 1850672 | 5606 | 0.008 | 0.4720 | No | ||
82 | TROVE2 | 4850458 | 5672 | 0.008 | 0.4687 | No | ||
83 | USP25 | 3520035 | 5866 | 0.007 | 0.4584 | No | ||
84 | ATRX | 2340039 3610132 4210373 | 5876 | 0.007 | 0.4582 | No | ||
85 | CAB39 | 5720471 | 5943 | 0.007 | 0.4548 | No | ||
86 | PCDHA3 | 3840402 | 6048 | 0.006 | 0.4494 | No | ||
87 | SATB2 | 2470181 | 6076 | 0.006 | 0.4481 | No | ||
88 | YES1 | 6100050 | 6382 | 0.005 | 0.4317 | No | ||
89 | RAD9A | 110300 1940632 3990390 6040014 | 6851 | 0.003 | 0.4064 | No | ||
90 | PLAG1 | 1450142 3870139 6520039 | 6908 | 0.003 | 0.4035 | No | ||
91 | TDG | 2900358 2940079 | 6911 | 0.003 | 0.4035 | No | ||
92 | AMBN | 4150170 | 7043 | 0.002 | 0.3964 | No | ||
93 | ZIC3 | 380020 | 7085 | 0.002 | 0.3943 | No | ||
94 | CDH20 | 5420215 7100711 | 7345 | 0.002 | 0.3803 | No | ||
95 | KLF5 | 3840348 | 7369 | 0.001 | 0.3791 | No | ||
96 | MMP16 | 2680139 | 7380 | 0.001 | 0.3786 | No | ||
97 | CACNA1E | 840253 | 7522 | 0.001 | 0.3710 | No | ||
98 | XPO1 | 540707 | 7754 | 0.000 | 0.3585 | No | ||
99 | EREG | 50519 4920129 | 7933 | -0.000 | 0.3488 | No | ||
100 | WRNIP1 | 2320541 5890725 | 7969 | -0.000 | 0.3469 | No | ||
101 | ELL2 | 6420091 | 8041 | -0.000 | 0.3431 | No | ||
102 | KCNS3 | 4150039 | 8092 | -0.001 | 0.3404 | No | ||
103 | TMEM47 | 1660086 | 8311 | -0.001 | 0.3286 | No | ||
104 | ADAM10 | 3780156 | 8393 | -0.001 | 0.3243 | No | ||
105 | TAF5 | 3450288 5890193 6860435 | 8420 | -0.001 | 0.3229 | No | ||
106 | EYA4 | 5360286 | 8490 | -0.002 | 0.3192 | No | ||
107 | BTBD3 | 1980041 2510577 3190053 4200746 | 8628 | -0.002 | 0.3118 | No | ||
108 | ESRRG | 4010181 | 8681 | -0.002 | 0.3091 | No | ||
109 | BANP | 940528 | 9095 | -0.003 | 0.2868 | No | ||
110 | CHES1 | 4570121 5700162 | 9265 | -0.004 | 0.2778 | No | ||
111 | PCDHA10 | 3830725 | 9646 | -0.005 | 0.2573 | No | ||
112 | RAP1A | 1090025 | 9652 | -0.005 | 0.2572 | No | ||
113 | EIF3S1 | 6130368 6770044 | 9725 | -0.005 | 0.2535 | No | ||
114 | RBMS3 | 6110722 | 9952 | -0.006 | 0.2414 | No | ||
115 | POGZ | 870348 7040286 | 9967 | -0.006 | 0.2408 | No | ||
116 | PHOX2B | 5270075 | 10089 | -0.006 | 0.2345 | No | ||
117 | PLXNC1 | 5860315 | 10167 | -0.007 | 0.2305 | No | ||
118 | IPO7 | 2190746 | 10257 | -0.007 | 0.2259 | No | ||
119 | PCDHA12 | 2810215 | 10452 | -0.008 | 0.2156 | No | ||
120 | RKHD3 | 6180471 | 10664 | -0.009 | 0.2045 | No | ||
121 | CALN1 | 3610722 | 10703 | -0.009 | 0.2027 | No | ||
122 | ENAH | 1690292 5700300 | 10730 | -0.009 | 0.2015 | No | ||
123 | TRIM41 | 4070019 6110670 | 10748 | -0.009 | 0.2009 | No | ||
124 | NPAS2 | 770670 | 10812 | -0.009 | 0.1978 | No | ||
125 | RAB18 | 3120575 4590577 | 10845 | -0.009 | 0.1963 | No | ||
126 | NAP1L5 | 360576 | 10939 | -0.010 | 0.1916 | No | ||
127 | PAK7 | 3830164 | 11193 | -0.011 | 0.1782 | No | ||
128 | FLRT3 | 70685 2760497 6040519 | 11275 | -0.011 | 0.1742 | No | ||
129 | CALD1 | 1770129 1940397 | 11382 | -0.012 | 0.1688 | No | ||
130 | BMPR1A | 2190193 4060603 | 11407 | -0.012 | 0.1679 | No | ||
131 | RAI2 | 6770333 | 11459 | -0.012 | 0.1655 | No | ||
132 | DBN1 | 7100537 | 11966 | -0.015 | 0.1385 | No | ||
133 | SEMA6D | 4050324 5860138 6350307 | 12205 | -0.017 | 0.1262 | No | ||
134 | PPP2R5B | 2900441 | 12809 | -0.023 | 0.0942 | No | ||
135 | SMCR8 | 730653 | 12826 | -0.023 | 0.0940 | No | ||
136 | CREB5 | 2320368 | 12960 | -0.024 | 0.0876 | No | ||
137 | ARID5B | 110403 | 13048 | -0.026 | 0.0837 | No | ||
138 | PCDHA6 | 780333 2370280 | 13084 | -0.026 | 0.0826 | No | ||
139 | CDH2 | 520435 2450451 2760025 6650477 | 13234 | -0.028 | 0.0754 | No | ||
140 | ABCA12 | 4540156 | 13252 | -0.028 | 0.0753 | No | ||
141 | HECTD2 | 2680014 3060689 | 13546 | -0.033 | 0.0605 | No | ||
142 | HIVEP2 | 6520538 | 13657 | -0.035 | 0.0556 | No | ||
143 | PCSK7 | 6370450 | 13794 | -0.037 | 0.0493 | No | ||
144 | PCDHA5 | 2970347 | 14046 | -0.042 | 0.0370 | No | ||
145 | A2BP1 | 2370390 4590593 5550014 | 14204 | -0.046 | 0.0299 | No | ||
146 | LPHN1 | 1400113 3130301 | 14414 | -0.051 | 0.0202 | No | ||
147 | UNC5A | 2120528 3060324 | 14467 | -0.053 | 0.0190 | No | ||
148 | MXI1 | 5050064 5130484 | 14746 | -0.061 | 0.0059 | No | ||
149 | GSPT2 | 6590674 | 14826 | -0.065 | 0.0036 | No | ||
150 | ATXN1 | 5550156 | 14909 | -0.068 | 0.0013 | No | ||
151 | NR4A2 | 60273 | 15039 | -0.073 | -0.0035 | No | ||
152 | PCDHA11 | 1510253 | 15128 | -0.078 | -0.0058 | No | ||
153 | CDK6 | 4920253 | 15168 | -0.079 | -0.0055 | No | ||
154 | KCNH7 | 7510068 | 15287 | -0.086 | -0.0092 | No | ||
155 | PHF1 | 4010577 6420053 | 15333 | -0.089 | -0.0089 | No | ||
156 | TNFRSF21 | 6380100 | 15441 | -0.096 | -0.0117 | No | ||
157 | DAB2 | 60309 | 15688 | -0.112 | -0.0216 | No | ||
158 | IGF1R | 3360494 | 15971 | -0.138 | -0.0326 | No | ||
159 | SON | 3120148 5860239 7040403 | 16165 | -0.158 | -0.0381 | No | ||
160 | FKBP1A | 2450368 | 16447 | -0.193 | -0.0474 | No | ||
161 | TRAF7 | 1190341 | 16549 | -0.207 | -0.0464 | No | ||
162 | ARMCX2 | 2320167 | 16644 | -0.219 | -0.0447 | No | ||
163 | MRPS25 | 610441 870128 1410368 | 16674 | -0.223 | -0.0393 | No | ||
164 | BHLHB2 | 7040603 | 16979 | -0.269 | -0.0475 | No | ||
165 | SLC10A3 | 2470563 | 17291 | -0.330 | -0.0541 | No | ||
166 | DHDDS | 940148 6650184 | 17419 | -0.355 | -0.0500 | No | ||
167 | PLK2 | 6450152 | 17660 | -0.416 | -0.0501 | No | ||
168 | PLK3 | 2640592 | 17834 | -0.475 | -0.0447 | No | ||
169 | RHOG | 6760575 | 17932 | -0.516 | -0.0339 | No | ||
170 | PPM1B | 380180 450154 3610215 | 18181 | -0.684 | -0.0261 | No | ||
171 | NCDN | 50040 1980739 3520603 | 18539 | -1.599 | 0.0042 | No |