Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | ATTCTTT,MIR-186 |
Enrichment Score (ES) | 0.5925206 |
Normalized Enrichment Score (NES) | 1.6511995 |
Nominal p-value | 0.0 |
FDR q-value | 0.030633064 |
FWER p-Value | 0.235 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | APLP2 | 3610037 | 211 | 0.895 | 0.0244 | Yes | ||
2 | EIF2S2 | 770095 2810487 | 224 | 0.876 | 0.0588 | Yes | ||
3 | MBNL1 | 2640762 7100048 | 235 | 0.865 | 0.0928 | Yes | ||
4 | PARG | 50139 | 237 | 0.861 | 0.1273 | Yes | ||
5 | SRPK2 | 6380341 | 304 | 0.780 | 0.1549 | Yes | ||
6 | SUMO1 | 1990364 2760338 6380195 | 389 | 0.696 | 0.1782 | Yes | ||
7 | NASP | 2260139 2940369 5130707 | 411 | 0.676 | 0.2042 | Yes | ||
8 | EED | 2320373 | 418 | 0.671 | 0.2307 | Yes | ||
9 | APRIN | 2810050 | 453 | 0.652 | 0.2550 | Yes | ||
10 | CLK4 | 3440484 3610156 | 479 | 0.636 | 0.2791 | Yes | ||
11 | RIOK3 | 1980487 4480619 7040026 | 513 | 0.614 | 0.3019 | Yes | ||
12 | MTPN | 3940167 | 514 | 0.614 | 0.3265 | Yes | ||
13 | ZHX1 | 2100110 2120286 | 532 | 0.606 | 0.3498 | Yes | ||
14 | BCL11B | 2680673 | 697 | 0.514 | 0.3615 | Yes | ||
15 | MBNL2 | 3450707 | 711 | 0.509 | 0.3811 | Yes | ||
16 | PABPC1 | 2650180 2690253 6020632 1990270 | 750 | 0.488 | 0.3986 | Yes | ||
17 | SGPP1 | 3930707 | 876 | 0.441 | 0.4095 | Yes | ||
18 | AHCYL1 | 540609 | 879 | 0.440 | 0.4270 | Yes | ||
19 | DPH2 | 2100402 3060039 | 880 | 0.439 | 0.4446 | Yes | ||
20 | EPC2 | 2470095 | 887 | 0.437 | 0.4618 | Yes | ||
21 | DDX3X | 2190020 | 934 | 0.421 | 0.4761 | Yes | ||
22 | POLS | 5890438 | 951 | 0.415 | 0.4919 | Yes | ||
23 | PDCD10 | 4760500 | 982 | 0.404 | 0.5064 | Yes | ||
24 | CDC42 | 1240168 3440278 4480519 5290162 | 986 | 0.401 | 0.5223 | Yes | ||
25 | TOB1 | 4150138 | 1181 | 0.340 | 0.5254 | Yes | ||
26 | RNF11 | 3990068 5080458 | 1231 | 0.327 | 0.5359 | Yes | ||
27 | MORC2 | 2370750 | 1467 | 0.263 | 0.5336 | Yes | ||
28 | MAPKAP1 | 1660161 2450575 | 1486 | 0.259 | 0.5430 | Yes | ||
29 | SLC23A2 | 6660722 | 1550 | 0.245 | 0.5494 | Yes | ||
30 | CTSB | 1400524 2360064 | 1738 | 0.211 | 0.5477 | Yes | ||
31 | HNRPU | 6520736 | 1815 | 0.196 | 0.5515 | Yes | ||
32 | TGFBR2 | 1780711 1980537 6550398 | 1826 | 0.195 | 0.5587 | Yes | ||
33 | LRBA | 3450402 | 1844 | 0.191 | 0.5654 | Yes | ||
34 | P2RX7 | 6020048 6380053 6510121 | 1908 | 0.182 | 0.5693 | Yes | ||
35 | RPS6KA3 | 1980707 | 2067 | 0.158 | 0.5670 | Yes | ||
36 | NFAT5 | 2510411 5890195 6550152 | 2188 | 0.140 | 0.5662 | Yes | ||
37 | PURB | 5360138 | 2214 | 0.136 | 0.5702 | Yes | ||
38 | BTF3 | 6940279 | 2258 | 0.131 | 0.5731 | Yes | ||
39 | ENC1 | 4810348 | 2393 | 0.117 | 0.5705 | Yes | ||
40 | TCF20 | 1190338 1240520 4070594 4810440 | 2394 | 0.117 | 0.5752 | Yes | ||
41 | FBXO33 | 1510504 | 2405 | 0.115 | 0.5793 | Yes | ||
42 | MRPL3 | 1170736 5270025 | 2407 | 0.115 | 0.5839 | Yes | ||
43 | MAPK1 | 3190193 6200253 | 2463 | 0.109 | 0.5853 | Yes | ||
44 | PCDHA7 | 1850019 | 2477 | 0.108 | 0.5889 | Yes | ||
45 | GABPB2 | 6130450 7050735 | 2652 | 0.093 | 0.5832 | Yes | ||
46 | PSME3 | 2810537 | 2703 | 0.089 | 0.5840 | Yes | ||
47 | STAG2 | 4540132 | 2779 | 0.084 | 0.5833 | Yes | ||
48 | PRPF39 | 1090088 | 2801 | 0.082 | 0.5854 | Yes | ||
49 | NARG1 | 5910563 6350095 | 2812 | 0.081 | 0.5881 | Yes | ||
50 | UBE3A | 1240152 2690438 5860609 | 2830 | 0.080 | 0.5904 | Yes | ||
51 | SLC25A3 | 670112 | 2850 | 0.079 | 0.5925 | Yes | ||
52 | SUCLA2 | 730632 1170292 | 2969 | 0.070 | 0.5889 | No | ||
53 | SYAP1 | 1410500 | 3042 | 0.065 | 0.5876 | No | ||
54 | PPP1CC | 6380300 2510647 | 3072 | 0.063 | 0.5886 | No | ||
55 | GPR85 | 5130750 5910020 | 3178 | 0.056 | 0.5851 | No | ||
56 | PTGES3 | 2190440 2680524 | 3191 | 0.056 | 0.5867 | No | ||
57 | MOSPD1 | 2030170 5270156 6900142 | 3193 | 0.056 | 0.5889 | No | ||
58 | EFCBP1 | 5860450 | 3220 | 0.054 | 0.5896 | No | ||
59 | ACSL4 | 510020 1240041 3190050 4540500 5570463 | 3437 | 0.044 | 0.5797 | No | ||
60 | FNDC3A | 2690097 3290044 | 3531 | 0.040 | 0.5762 | No | ||
61 | NME7 | 60170 1230551 2850333 4200102 4560411 5090647 | 3541 | 0.040 | 0.5774 | No | ||
62 | NR5A2 | 1690180 6900050 | 3580 | 0.039 | 0.5769 | No | ||
63 | CAST | 3850082 5420671 6200156 | 3601 | 0.038 | 0.5773 | No | ||
64 | RAB6A | 3840463 4780731 | 3663 | 0.035 | 0.5754 | No | ||
65 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 3738 | 0.033 | 0.5727 | No | ||
66 | HOOK3 | 1190242 2470059 | 3763 | 0.033 | 0.5727 | No | ||
67 | CDC5L | 3130446 3390025 6400204 | 3840 | 0.030 | 0.5698 | No | ||
68 | SEPT7 | 2760685 | 3972 | 0.027 | 0.5638 | No | ||
69 | EPN2 | 1340451 6550239 6860020 6860403 | 4015 | 0.026 | 0.5626 | No | ||
70 | QKI | 5220093 6130044 | 4130 | 0.024 | 0.5573 | No | ||
71 | HOXA9 | 610494 4730040 5130601 | 4174 | 0.023 | 0.5559 | No | ||
72 | NCOA2 | 940347 2850725 | 4223 | 0.022 | 0.5542 | No | ||
73 | CSNK2A1 | 1580577 | 4373 | 0.020 | 0.5469 | No | ||
74 | CCNT2 | 2100390 4150563 | 4420 | 0.019 | 0.5452 | No | ||
75 | ITGA6 | 3830129 | 4560 | 0.017 | 0.5383 | No | ||
76 | SENP6 | 1340592 4730142 | 4565 | 0.017 | 0.5388 | No | ||
77 | WNT5A | 840685 3120152 | 4850 | 0.014 | 0.5239 | No | ||
78 | OTX1 | 2510215 | 4859 | 0.014 | 0.5240 | No | ||
79 | LRCH2 | 2900162 | 4878 | 0.014 | 0.5236 | No | ||
80 | PCDHA1 | 940026 540484 | 4928 | 0.013 | 0.5215 | No | ||
81 | CAPZA1 | 3140390 | 4969 | 0.013 | 0.5198 | No | ||
82 | DDX3Y | 1580278 4200519 | 4985 | 0.013 | 0.5195 | No | ||
83 | BCAR3 | 1660717 | 5002 | 0.013 | 0.5191 | No | ||
84 | PSMD11 | 2340538 6510053 | 5043 | 0.012 | 0.5175 | No | ||
85 | DPP9 | 6660441 | 5177 | 0.011 | 0.5107 | No | ||
86 | BIRC4 | 1400129 6960128 | 5466 | 0.009 | 0.4954 | No | ||
87 | AMOT | 1940121 2940647 6590093 | 5491 | 0.009 | 0.4945 | No | ||
88 | NEGR1 | 1940731 5130170 | 5509 | 0.009 | 0.4939 | No | ||
89 | LIN28 | 6590672 | 5827 | 0.007 | 0.4770 | No | ||
90 | HNMT | 4560022 | 5927 | 0.007 | 0.4719 | No | ||
91 | SOX11 | 610279 | 5967 | 0.007 | 0.4700 | No | ||
92 | PCDHA3 | 3840402 | 6048 | 0.006 | 0.4659 | No | ||
93 | UBE2B | 4780497 | 6150 | 0.006 | 0.4607 | No | ||
94 | PLS3 | 3290082 | 6374 | 0.005 | 0.4488 | No | ||
95 | SNAP91 | 3170056 5690520 | 6416 | 0.005 | 0.4467 | No | ||
96 | INSM1 | 3450671 | 6526 | 0.004 | 0.4410 | No | ||
97 | MITF | 380056 | 6583 | 0.004 | 0.4381 | No | ||
98 | GABRA4 | 6290465 | 6650 | 0.004 | 0.4347 | No | ||
99 | CRK | 1230162 4780128 | 6657 | 0.004 | 0.4345 | No | ||
100 | YY1 | 6130451 | 6671 | 0.004 | 0.4340 | No | ||
101 | EFEMP1 | 5860324 | 6787 | 0.003 | 0.4278 | No | ||
102 | ZCCHC11 | 3390731 5360039 | 6842 | 0.003 | 0.4250 | No | ||
103 | MYT1 | 6770524 | 6945 | 0.003 | 0.4196 | No | ||
104 | SALL1 | 5420020 7050195 | 6957 | 0.003 | 0.4191 | No | ||
105 | KCNMA1 | 1450402 | 7396 | 0.001 | 0.3954 | No | ||
106 | FOXD1 | 6860053 | 7458 | 0.001 | 0.3921 | No | ||
107 | TLOC1 | 4050309 | 7476 | 0.001 | 0.3913 | No | ||
108 | MYT1L | 5670369 6660403 | 7568 | 0.001 | 0.3864 | No | ||
109 | SP3 | 3840338 | 7644 | 0.001 | 0.3823 | No | ||
110 | PSPH | 4050020 | 7716 | 0.000 | 0.3785 | No | ||
111 | PNN | 6650504 | 7783 | 0.000 | 0.3749 | No | ||
112 | ZFP36L1 | 2510138 4120048 | 7959 | -0.000 | 0.3654 | No | ||
113 | RPS6KB1 | 1450427 5080110 6200563 | 8448 | -0.002 | 0.3390 | No | ||
114 | ZFHX4 | 6110167 | 8518 | -0.002 | 0.3353 | No | ||
115 | SP4 | 3850176 | 8548 | -0.002 | 0.3338 | No | ||
116 | BTBD3 | 1980041 2510577 3190053 4200746 | 8628 | -0.002 | 0.3296 | No | ||
117 | LRRN1 | 3290154 | 8811 | -0.003 | 0.3198 | No | ||
118 | KCND2 | 1170128 2100112 | 9005 | -0.003 | 0.3095 | No | ||
119 | CD200R1 | 630593 | 9006 | -0.003 | 0.3096 | No | ||
120 | CACNB3 | 2480035 4540184 | 9115 | -0.003 | 0.3039 | No | ||
121 | CLDN1 | 5670746 | 9127 | -0.003 | 0.3034 | No | ||
122 | ZCCHC14 | 5900288 | 9224 | -0.004 | 0.2984 | No | ||
123 | JPH3 | 780397 | 9272 | -0.004 | 0.2960 | No | ||
124 | DNM3 | 730711 | 9296 | -0.004 | 0.2949 | No | ||
125 | GRIN3A | 2370592 | 9413 | -0.004 | 0.2888 | No | ||
126 | UBQLN2 | 430397 1170594 4070121 | 9490 | -0.005 | 0.2848 | No | ||
127 | LMBR1 | 4570072 | 9576 | -0.005 | 0.2804 | No | ||
128 | PCDHA10 | 3830725 | 9646 | -0.005 | 0.2768 | No | ||
129 | NR3C2 | 2480324 6400093 | 9724 | -0.005 | 0.2729 | No | ||
130 | WDFY3 | 3610041 4560333 4570273 | 9963 | -0.006 | 0.2602 | No | ||
131 | JAG1 | 3440390 | 10130 | -0.007 | 0.2515 | No | ||
132 | CXXC5 | 840010 | 10198 | -0.007 | 0.2481 | No | ||
133 | IGSF11 | 60471 2350288 | 10432 | -0.008 | 0.2358 | No | ||
134 | PCDHA12 | 2810215 | 10452 | -0.008 | 0.2350 | No | ||
135 | TPR | 1990066 6550390 | 10510 | -0.008 | 0.2323 | No | ||
136 | RKHD3 | 6180471 | 10664 | -0.009 | 0.2243 | No | ||
137 | PRDM1 | 3170347 3520301 | 10835 | -0.009 | 0.2155 | No | ||
138 | IL2 | 1770725 | 10874 | -0.009 | 0.2138 | No | ||
139 | CPEB3 | 3940164 | 10953 | -0.010 | 0.2099 | No | ||
140 | MCFD2 | 520576 5690017 | 10962 | -0.010 | 0.2099 | No | ||
141 | LPHN2 | 4480010 | 11157 | -0.011 | 0.1998 | No | ||
142 | PAK7 | 3830164 | 11193 | -0.011 | 0.1983 | No | ||
143 | SMAD6 | 870504 | 11248 | -0.011 | 0.1959 | No | ||
144 | WNK3 | 4060053 | 11477 | -0.012 | 0.1840 | No | ||
145 | OSBPL8 | 50603 | 11480 | -0.012 | 0.1844 | No | ||
146 | TRPC1 | 3120189 4210537 | 11657 | -0.013 | 0.1753 | No | ||
147 | SRPK1 | 450110 | 11769 | -0.014 | 0.1699 | No | ||
148 | EPHB1 | 4610056 | 11786 | -0.014 | 0.1696 | No | ||
149 | CNTNAP2 | 360170 4280546 | 11788 | -0.014 | 0.1701 | No | ||
150 | MAP3K2 | 380270 | 11971 | -0.015 | 0.1608 | No | ||
151 | CALB1 | 460070 | 12242 | -0.018 | 0.1469 | No | ||
152 | NXPH1 | 3870546 | 12507 | -0.020 | 0.1333 | No | ||
153 | PDGFC | 4200133 | 12727 | -0.022 | 0.1223 | No | ||
154 | SMPD3 | 520164 | 12739 | -0.022 | 0.1226 | No | ||
155 | PCDHA6 | 780333 2370280 | 13084 | -0.026 | 0.1050 | No | ||
156 | HOXB8 | 3710450 | 13150 | -0.027 | 0.1025 | No | ||
157 | CUGBP1 | 450292 510022 7050176 7050215 | 13251 | -0.028 | 0.0982 | No | ||
158 | BACH2 | 6760131 | 13375 | -0.030 | 0.0928 | No | ||
159 | CNTNAP1 | 6650132 | 13381 | -0.030 | 0.0937 | No | ||
160 | PAPPA | 4230463 | 13641 | -0.034 | 0.0810 | No | ||
161 | ZNF385 | 450176 4810358 | 13900 | -0.039 | 0.0686 | No | ||
162 | JPH1 | 610739 | 13903 | -0.039 | 0.0700 | No | ||
163 | PPM1G | 610725 | 13957 | -0.040 | 0.0688 | No | ||
164 | RAB21 | 5570070 | 14010 | -0.041 | 0.0676 | No | ||
165 | PCDHA5 | 2970347 | 14046 | -0.042 | 0.0674 | No | ||
166 | SPAST | 460603 4070471 4210132 4670338 | 14167 | -0.045 | 0.0627 | No | ||
167 | DOK6 | 4850673 | 14169 | -0.045 | 0.0644 | No | ||
168 | RB1CC1 | 510494 7100072 | 14171 | -0.045 | 0.0662 | No | ||
169 | A2BP1 | 2370390 4590593 5550014 | 14204 | -0.046 | 0.0662 | No | ||
170 | TRPS1 | 870100 | 14250 | -0.047 | 0.0657 | No | ||
171 | RBM9 | 2510092 6290088 | 14515 | -0.054 | 0.0535 | No | ||
172 | PPP1CB | 3130411 3780270 4150180 | 14533 | -0.055 | 0.0548 | No | ||
173 | GNAZ | 6130296 | 14724 | -0.061 | 0.0469 | No | ||
174 | COL3A1 | 6420273 6620044 | 14743 | -0.061 | 0.0484 | No | ||
175 | EIF3S10 | 1190079 3840176 | 14916 | -0.068 | 0.0418 | No | ||
176 | EIF4E | 1580403 70133 6380215 | 14939 | -0.069 | 0.0433 | No | ||
177 | NR4A2 | 60273 | 15039 | -0.073 | 0.0409 | No | ||
178 | PCDHA11 | 1510253 | 15128 | -0.078 | 0.0392 | No | ||
179 | BUB3 | 3170546 | 15296 | -0.087 | 0.0336 | No | ||
180 | DLC1 | 1090632 6450594 | 15335 | -0.089 | 0.0351 | No | ||
181 | TMEM35 | 2640446 | 15530 | -0.101 | 0.0287 | No | ||
182 | DLG5 | 450215 | 15582 | -0.104 | 0.0301 | No | ||
183 | RABIF | 2370458 5910543 | 15599 | -0.105 | 0.0334 | No | ||
184 | ZFAND3 | 2760504 | 15718 | -0.114 | 0.0316 | No | ||
185 | FRMD4A | 2190176 | 15841 | -0.126 | 0.0300 | No | ||
186 | CPEB2 | 4760338 | 15901 | -0.130 | 0.0320 | No | ||
187 | RBM16 | 6290286 6400181 | 16164 | -0.158 | 0.0241 | No | ||
188 | BCL9 | 7100112 | 16185 | -0.161 | 0.0294 | No | ||
189 | HYOU1 | 3060465 | 16412 | -0.189 | 0.0248 | No | ||
190 | RASA3 | 2060465 | 16424 | -0.190 | 0.0318 | No | ||
191 | EXT2 | 6520239 | 16747 | -0.235 | 0.0237 | No | ||
192 | CXCL13 | 6290402 | 17144 | -0.300 | 0.0143 | No | ||
193 | TARDBP | 870390 2350093 | 17678 | -0.419 | 0.0021 | No | ||
194 | LGTN | 450332 | 17969 | -0.532 | 0.0077 | No | ||
195 | PPM1B | 380180 450154 3610215 | 18181 | -0.684 | 0.0236 | No |