Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | ATGTACA,MIR-493 |
Enrichment Score (ES) | 0.6760437 |
Normalized Enrichment Score (NES) | 1.8646241 |
Nominal p-value | 0.0 |
FDR q-value | 8.773886E-4 |
FWER p-Value | 0.0010 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ARID1A | 2630022 1690551 4810110 | 0 | 6.327 | 0.1408 | Yes | ||
2 | BTG1 | 4200735 6040131 6200133 | 20 | 1.988 | 0.1839 | Yes | ||
3 | ATP2A2 | 1090075 3990279 | 62 | 1.475 | 0.2145 | Yes | ||
4 | PPP1R10 | 110136 3170725 3610484 | 77 | 1.334 | 0.2435 | Yes | ||
5 | HMGCS1 | 6620452 | 109 | 1.134 | 0.2670 | Yes | ||
6 | TTC7B | 4760725 | 128 | 1.077 | 0.2900 | Yes | ||
7 | PPP2R5D | 4010156 380408 5550112 5670162 | 167 | 0.968 | 0.3095 | Yes | ||
8 | MCL1 | 1660672 | 184 | 0.934 | 0.3294 | Yes | ||
9 | APLP2 | 3610037 | 211 | 0.895 | 0.3479 | Yes | ||
10 | TBK1 | 5690338 | 231 | 0.870 | 0.3662 | Yes | ||
11 | CLPX | 6220156 | 259 | 0.838 | 0.3834 | Yes | ||
12 | KLF3 | 5130438 | 271 | 0.818 | 0.4010 | Yes | ||
13 | BRD7 | 2120068 6200746 | 273 | 0.812 | 0.4190 | Yes | ||
14 | AP3S1 | 5570044 | 297 | 0.785 | 0.4352 | Yes | ||
15 | SRPK2 | 6380341 | 304 | 0.780 | 0.4522 | Yes | ||
16 | PIAS1 | 5340301 | 305 | 0.780 | 0.4695 | Yes | ||
17 | ETF1 | 6770075 | 307 | 0.780 | 0.4868 | Yes | ||
18 | DAB2IP | 3170064 6200441 | 308 | 0.779 | 0.5042 | Yes | ||
19 | RHOT1 | 6760692 | 327 | 0.763 | 0.5202 | Yes | ||
20 | UBE2G1 | 2230546 5420528 7040463 | 403 | 0.683 | 0.5313 | Yes | ||
21 | DHX36 | 2470465 | 436 | 0.659 | 0.5442 | Yes | ||
22 | PPP3CB | 6020156 | 480 | 0.635 | 0.5560 | Yes | ||
23 | MTPN | 3940167 | 514 | 0.614 | 0.5679 | Yes | ||
24 | ZFX | 5900400 | 647 | 0.540 | 0.5727 | Yes | ||
25 | MBNL2 | 3450707 | 711 | 0.509 | 0.5806 | Yes | ||
26 | BCL7A | 4560095 | 735 | 0.495 | 0.5903 | Yes | ||
27 | SIN3A | 2190121 | 788 | 0.476 | 0.5981 | Yes | ||
28 | SFRS3 | 770315 4230593 | 810 | 0.468 | 0.6074 | Yes | ||
29 | CTDSPL | 4670546 | 861 | 0.447 | 0.6146 | Yes | ||
30 | NMT1 | 5810152 | 868 | 0.444 | 0.6242 | Yes | ||
31 | DDX3X | 2190020 | 934 | 0.421 | 0.6300 | Yes | ||
32 | IRF2 | 5390044 | 998 | 0.397 | 0.6354 | Yes | ||
33 | NCOA1 | 3610438 | 1155 | 0.346 | 0.6346 | Yes | ||
34 | CREBBP | 5690035 7040050 | 1235 | 0.327 | 0.6376 | Yes | ||
35 | PAIP1 | 3870576 | 1301 | 0.308 | 0.6409 | Yes | ||
36 | ITSN2 | 780484 | 1322 | 0.301 | 0.6465 | Yes | ||
37 | CUGBP2 | 6180121 6840139 | 1530 | 0.249 | 0.6408 | Yes | ||
38 | EIF4ENIF1 | 2060341 | 1616 | 0.232 | 0.6413 | Yes | ||
39 | KBTBD2 | 2320014 | 1663 | 0.223 | 0.6438 | Yes | ||
40 | UTX | 2900017 6770452 | 1692 | 0.218 | 0.6471 | Yes | ||
41 | CDC73 | 1580132 | 1708 | 0.216 | 0.6511 | Yes | ||
42 | ITGB1 | 5080156 6270528 | 1739 | 0.211 | 0.6542 | Yes | ||
43 | PHF2 | 4060300 | 1747 | 0.210 | 0.6585 | Yes | ||
44 | PDPK1 | 6650168 | 1779 | 0.204 | 0.6613 | Yes | ||
45 | FMNL2 | 4060438 | 1799 | 0.199 | 0.6647 | Yes | ||
46 | DNAJC13 | 4730091 | 1846 | 0.190 | 0.6665 | Yes | ||
47 | EFTUD1 | 5360736 | 1875 | 0.185 | 0.6691 | Yes | ||
48 | RYBP | 60746 | 1883 | 0.184 | 0.6728 | Yes | ||
49 | DCUN1D1 | 2360332 | 1985 | 0.171 | 0.6711 | Yes | ||
50 | CDC14A | 4050132 | 2011 | 0.167 | 0.6735 | Yes | ||
51 | SIPA1L2 | 4850731 | 2031 | 0.163 | 0.6760 | Yes | ||
52 | NUDT4 | 6760689 | 2116 | 0.150 | 0.6748 | No | ||
53 | MLLT10 | 1410288 3290142 | 2284 | 0.128 | 0.6686 | No | ||
54 | FBXO33 | 1510504 | 2405 | 0.115 | 0.6646 | No | ||
55 | RBBP6 | 2320129 | 2430 | 0.113 | 0.6658 | No | ||
56 | MADD | 6100725 7000088 | 2451 | 0.111 | 0.6672 | No | ||
57 | MAPK1 | 3190193 6200253 | 2463 | 0.109 | 0.6691 | No | ||
58 | FOXO1A | 3120670 | 2520 | 0.104 | 0.6683 | No | ||
59 | ARFGEF1 | 6760494 | 2535 | 0.103 | 0.6699 | No | ||
60 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 2587 | 0.099 | 0.6693 | No | ||
61 | XPO7 | 2630215 6760014 | 2599 | 0.097 | 0.6708 | No | ||
62 | CARM1 | 7040292 | 2623 | 0.096 | 0.6717 | No | ||
63 | GNB1 | 2120397 | 2648 | 0.093 | 0.6725 | No | ||
64 | UBE3A | 1240152 2690438 5860609 | 2830 | 0.080 | 0.6644 | No | ||
65 | PDE4D | 2470528 6660014 | 2880 | 0.076 | 0.6635 | No | ||
66 | ANKRD17 | 2120402 3850035 6400044 | 2962 | 0.070 | 0.6606 | No | ||
67 | SPIRE2 | 450088 | 2995 | 0.068 | 0.6604 | No | ||
68 | PHF12 | 870400 3130687 | 3121 | 0.060 | 0.6549 | No | ||
69 | FBS1 | 2570520 | 3129 | 0.060 | 0.6559 | No | ||
70 | AR | 6380167 | 3192 | 0.056 | 0.6537 | No | ||
71 | RPS6KA5 | 2120563 7040546 | 3195 | 0.055 | 0.6549 | No | ||
72 | AXIN1 | 3360358 6940451 | 3268 | 0.051 | 0.6521 | No | ||
73 | GTF2IRD1 | 2030154 3990040 5080372 | 3316 | 0.049 | 0.6506 | No | ||
74 | SH2D3C | 3060014 | 3320 | 0.049 | 0.6516 | No | ||
75 | E2F6 | 3120133 3850332 4070324 | 3403 | 0.046 | 0.6481 | No | ||
76 | BAZ2A | 730184 | 3525 | 0.041 | 0.6425 | No | ||
77 | RALGPS1 | 3440129 6400746 | 3581 | 0.039 | 0.6403 | No | ||
78 | CLASP1 | 6860279 | 3615 | 0.037 | 0.6394 | No | ||
79 | HEMGN | 670411 | 3694 | 0.035 | 0.6359 | No | ||
80 | TLE4 | 1450064 1500519 | 3821 | 0.031 | 0.6297 | No | ||
81 | RBM12 | 4570239 6040411 6660129 | 3833 | 0.031 | 0.6298 | No | ||
82 | JARID1B | 4730494 | 3881 | 0.030 | 0.6279 | No | ||
83 | EIF2C1 | 6900551 | 3904 | 0.029 | 0.6274 | No | ||
84 | SSH2 | 360056 | 4096 | 0.024 | 0.6175 | No | ||
85 | THRAP2 | 4920600 | 4187 | 0.023 | 0.6131 | No | ||
86 | NAB1 | 430739 1230114 3390736 6660056 | 4211 | 0.022 | 0.6124 | No | ||
87 | CCNT2 | 2100390 4150563 | 4420 | 0.019 | 0.6015 | No | ||
88 | SPRED2 | 510138 540195 | 4430 | 0.019 | 0.6014 | No | ||
89 | PCGF2 | 6370347 | 4484 | 0.018 | 0.5990 | No | ||
90 | TJP1 | 6350184 | 4547 | 0.017 | 0.5960 | No | ||
91 | SORCS3 | 5700309 | 4656 | 0.016 | 0.5905 | No | ||
92 | KIF1B | 1240494 2370139 4570270 6510102 | 4683 | 0.016 | 0.5894 | No | ||
93 | RSBN1 | 7000487 | 4697 | 0.016 | 0.5890 | No | ||
94 | PBX3 | 1300424 3710577 6180575 | 4765 | 0.015 | 0.5857 | No | ||
95 | PIP5K3 | 5360112 | 4846 | 0.014 | 0.5817 | No | ||
96 | WNT5A | 840685 3120152 | 4850 | 0.014 | 0.5818 | No | ||
97 | HIPK1 | 110193 | 4952 | 0.013 | 0.5766 | No | ||
98 | SEMA4C | 1980315 | 5227 | 0.011 | 0.5620 | No | ||
99 | PFN2 | 730040 5700026 | 5308 | 0.010 | 0.5579 | No | ||
100 | DUSP16 | 2370082 2480450 | 5438 | 0.009 | 0.5511 | No | ||
101 | SPEN | 2060041 | 6010 | 0.006 | 0.5202 | No | ||
102 | OSBPL6 | 3800072 | 6058 | 0.006 | 0.5177 | No | ||
103 | GPC4 | 5910408 | 6071 | 0.006 | 0.5172 | No | ||
104 | TNFSF11 | 6350204 | 6085 | 0.006 | 0.5167 | No | ||
105 | THRAP1 | 2470121 | 6442 | 0.005 | 0.4974 | No | ||
106 | GABRA5 | 5570215 | 6588 | 0.004 | 0.4896 | No | ||
107 | KCNIP4 | 4120435 7050605 | 6668 | 0.004 | 0.4854 | No | ||
108 | ZIC2 | 1410408 | 6676 | 0.004 | 0.4851 | No | ||
109 | GABRA1 | 130372 | 6712 | 0.004 | 0.4833 | No | ||
110 | SALL1 | 5420020 7050195 | 6957 | 0.003 | 0.4701 | No | ||
111 | PUM2 | 4200441 5910446 | 7014 | 0.003 | 0.4671 | No | ||
112 | UNC50 | 4920037 | 7069 | 0.002 | 0.4642 | No | ||
113 | BHLHB5 | 6510520 | 7261 | 0.002 | 0.4539 | No | ||
114 | NLGN1 | 5670278 | 7326 | 0.002 | 0.4504 | No | ||
115 | NLGN3 | 2650463 | 7376 | 0.001 | 0.4478 | No | ||
116 | DACH1 | 2450593 5700592 | 7395 | 0.001 | 0.4468 | No | ||
117 | KCNMA1 | 1450402 | 7396 | 0.001 | 0.4469 | No | ||
118 | PCDH18 | 430010 | 7419 | 0.001 | 0.4457 | No | ||
119 | SS18 | 1940440 2900072 6900129 | 7497 | 0.001 | 0.4415 | No | ||
120 | SP3 | 3840338 | 7644 | 0.001 | 0.4336 | No | ||
121 | NDST1 | 1500427 5340121 | 7881 | 0.000 | 0.4208 | No | ||
122 | RPE | 940114 | 8290 | -0.001 | 0.3986 | No | ||
123 | ADAM10 | 3780156 | 8393 | -0.001 | 0.3931 | No | ||
124 | SP4 | 3850176 | 8548 | -0.002 | 0.3848 | No | ||
125 | ZIC1 | 670113 | 8576 | -0.002 | 0.3834 | No | ||
126 | BHLHB3 | 3450438 | 8621 | -0.002 | 0.3810 | No | ||
127 | ARHGAP5 | 2510619 3360035 | 8649 | -0.002 | 0.3796 | No | ||
128 | ESRRG | 4010181 | 8681 | -0.002 | 0.3780 | No | ||
129 | PDZRN3 | 2340131 | 8954 | -0.003 | 0.3632 | No | ||
130 | SERTAD2 | 2810673 6840450 | 9008 | -0.003 | 0.3604 | No | ||
131 | SNX9 | 3290592 | 9022 | -0.003 | 0.3598 | No | ||
132 | PIK3R1 | 4730671 | 9200 | -0.004 | 0.3503 | No | ||
133 | EYA1 | 1450278 5220390 | 9222 | -0.004 | 0.3492 | No | ||
134 | RIMS3 | 3890563 | 9382 | -0.004 | 0.3407 | No | ||
135 | CPNE8 | 7040039 | 9458 | -0.004 | 0.3367 | No | ||
136 | DKK2 | 3610433 | 9590 | -0.005 | 0.3297 | No | ||
137 | CRSP6 | 2940358 | 9653 | -0.005 | 0.3264 | No | ||
138 | CSNK1A1 | 2340427 | 9666 | -0.005 | 0.3259 | No | ||
139 | EPHA7 | 1190288 4010278 | 9702 | -0.005 | 0.3241 | No | ||
140 | WDFY3 | 3610041 4560333 4570273 | 9963 | -0.006 | 0.3101 | No | ||
141 | FIGN | 7000601 | 10016 | -0.006 | 0.3074 | No | ||
142 | BCOR | 1660452 3940053 | 10044 | -0.006 | 0.3061 | No | ||
143 | PSD2 | 2060091 | 10109 | -0.007 | 0.3027 | No | ||
144 | TTN | 2320161 4670056 6550026 | 10134 | -0.007 | 0.3016 | No | ||
145 | SRPX | 580717 1980162 | 10208 | -0.007 | 0.2978 | No | ||
146 | NRXN3 | 1400546 3360471 | 10231 | -0.007 | 0.2967 | No | ||
147 | LRRTM3 | 4210021 | 10295 | -0.007 | 0.2935 | No | ||
148 | BASP1 | 5700044 | 10392 | -0.008 | 0.2884 | No | ||
149 | IRX3 | 4200112 | 10641 | -0.009 | 0.2751 | No | ||
150 | ENAH | 1690292 5700300 | 10730 | -0.009 | 0.2705 | No | ||
151 | SV2B | 3850717 | 10799 | -0.009 | 0.2670 | No | ||
152 | TMEFF1 | 2680100 | 10841 | -0.009 | 0.2650 | No | ||
153 | CDH11 | 1230133 2100180 4610110 | 10986 | -0.010 | 0.2574 | No | ||
154 | CAPN3 | 1980451 6940047 | 11272 | -0.011 | 0.2422 | No | ||
155 | ZBTB11 | 6520092 | 11280 | -0.011 | 0.2421 | No | ||
156 | MEF2C | 670025 780338 | 11283 | -0.011 | 0.2422 | No | ||
157 | FHOD3 | 1240541 | 11401 | -0.012 | 0.2361 | No | ||
158 | PTPN12 | 2030309 6020725 6130746 6290609 | 11405 | -0.012 | 0.2362 | No | ||
159 | GAB1 | 2970156 | 11487 | -0.012 | 0.2321 | No | ||
160 | FZD4 | 1580520 | 11677 | -0.014 | 0.2221 | No | ||
161 | UBE2V2 | 4210484 | 11875 | -0.015 | 0.2117 | No | ||
162 | CUL5 | 450142 | 12054 | -0.016 | 0.2024 | No | ||
163 | GRM5 | 60528 | 12103 | -0.016 | 0.2002 | No | ||
164 | HS3ST3B1 | 380040 | 12112 | -0.016 | 0.2001 | No | ||
165 | COBLL1 | 4230056 6370494 | 12175 | -0.017 | 0.1971 | No | ||
166 | POU4F1 | 2260315 | 12336 | -0.018 | 0.1888 | No | ||
167 | JUN | 840170 | 12454 | -0.019 | 0.1829 | No | ||
168 | NXPH1 | 3870546 | 12507 | -0.020 | 0.1805 | No | ||
169 | IL1A | 3610056 | 12515 | -0.020 | 0.1806 | No | ||
170 | AK5 | 6290348 | 12555 | -0.020 | 0.1789 | No | ||
171 | MARK1 | 450484 | 12605 | -0.021 | 0.1767 | No | ||
172 | PDGFC | 4200133 | 12727 | -0.022 | 0.1706 | No | ||
173 | SOX21 | 1050110 4670041 6660338 | 12804 | -0.023 | 0.1670 | No | ||
174 | DLL1 | 1770377 | 12807 | -0.023 | 0.1674 | No | ||
175 | TRAM2 | 3940112 | 12907 | -0.024 | 0.1625 | No | ||
176 | CDH13 | 5130368 5340114 | 13031 | -0.025 | 0.1564 | No | ||
177 | SDC2 | 1980168 | 13057 | -0.026 | 0.1556 | No | ||
178 | CDH2 | 520435 2450451 2760025 6650477 | 13234 | -0.028 | 0.1467 | No | ||
179 | MAST1 | 6940215 | 13601 | -0.033 | 0.1275 | No | ||
180 | HIVEP2 | 6520538 | 13657 | -0.035 | 0.1253 | No | ||
181 | SNAI1 | 6590253 | 13687 | -0.035 | 0.1245 | No | ||
182 | PPP2R5C | 3310121 6650672 | 13735 | -0.036 | 0.1227 | No | ||
183 | CITED2 | 5670114 5130088 | 13748 | -0.036 | 0.1229 | No | ||
184 | VPS13D | 2350451 | 13844 | -0.038 | 0.1186 | No | ||
185 | JPH1 | 610739 | 13903 | -0.039 | 0.1163 | No | ||
186 | GAD1 | 2360035 3140167 | 13993 | -0.041 | 0.1124 | No | ||
187 | TRPS1 | 870100 | 14250 | -0.047 | 0.0995 | No | ||
188 | RNF38 | 1940746 3140133 3840601 | 14311 | -0.048 | 0.0973 | No | ||
189 | TBC1D4 | 6420397 | 14465 | -0.053 | 0.0901 | No | ||
190 | UNC5A | 2120528 3060324 | 14467 | -0.053 | 0.0913 | No | ||
191 | ZMYND19 | 1570706 6860551 | 14479 | -0.053 | 0.0918 | No | ||
192 | AFF3 | 3870102 | 14486 | -0.053 | 0.0927 | No | ||
193 | GABRG2 | 2350402 4210204 6130279 6550037 | 14662 | -0.059 | 0.0845 | No | ||
194 | SNRP70 | 4200181 | 14714 | -0.060 | 0.0831 | No | ||
195 | FGF13 | 630575 1570440 5360121 | 14771 | -0.063 | 0.0814 | No | ||
196 | SPAG8 | 4280446 | 14787 | -0.063 | 0.0820 | No | ||
197 | SPRYD3 | 50403 | 14948 | -0.069 | 0.0749 | No | ||
198 | OVOL1 | 1690131 | 14955 | -0.070 | 0.0761 | No | ||
199 | KPNA4 | 510369 | 15210 | -0.081 | 0.0641 | No | ||
200 | TMEM16D | 2650324 | 15361 | -0.090 | 0.0579 | No | ||
201 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15465 | -0.097 | 0.0545 | No | ||
202 | LRP12 | 2370112 | 15507 | -0.100 | 0.0545 | No | ||
203 | CHKB | 770129 | 15685 | -0.112 | 0.0474 | No | ||
204 | ATAD2 | 870242 2260687 | 15909 | -0.131 | 0.0381 | No | ||
205 | VAMP2 | 2100100 | 15915 | -0.131 | 0.0408 | No | ||
206 | VGLL4 | 6860463 | 15966 | -0.137 | 0.0411 | No | ||
207 | CRSP7 | 4230408 | 16055 | -0.147 | 0.0396 | No | ||
208 | EFNA3 | 6370390 | 16110 | -0.152 | 0.0400 | No | ||
209 | DOCK9 | 5080037 | 16279 | -0.172 | 0.0347 | No | ||
210 | OTUB1 | 610551 | 16298 | -0.174 | 0.0376 | No | ||
211 | HIC2 | 4010433 | 16357 | -0.182 | 0.0385 | No | ||
212 | ANKRD50 | 870543 | 16603 | -0.214 | 0.0300 | No | ||
213 | ANTXR1 | 1990593 2850056 | 16614 | -0.217 | 0.0343 | No | ||
214 | ATP5A1 | 1990722 | 16617 | -0.217 | 0.0390 | No | ||
215 | HNRPA0 | 2680048 | 16849 | -0.251 | 0.0320 | No | ||
216 | IRF7 | 1570605 | 16971 | -0.268 | 0.0314 | No | ||
217 | SLC25A26 | 4210577 | 17263 | -0.324 | 0.0228 | No | ||
218 | USP21 | 3060446 | 17333 | -0.338 | 0.0266 | No | ||
219 | LRIG1 | 1050136 | 17712 | -0.432 | 0.0156 | No | ||
220 | PMP22 | 4010239 6550072 | 17895 | -0.499 | 0.0169 | No | ||
221 | UBE2Q1 | 610348 2350114 4210717 | 18394 | -1.001 | 0.0121 | No |