Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$TGIF_01 |
Enrichment Score (ES) | 0.5295305 |
Normalized Enrichment Score (NES) | 1.2806891 |
Nominal p-value | 0.048543688 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | INPPL1 | 110717 3120164 | 24 | 4.268 | 0.1105 | Yes | ||
2 | PCBP4 | 6350722 | 49 | 3.258 | 0.1945 | Yes | ||
3 | RBX1 | 2120010 2340047 | 65 | 2.959 | 0.2712 | Yes | ||
4 | GCAT | 5270672 | 119 | 2.325 | 0.3292 | Yes | ||
5 | WISP1 | 2340019 3130692 | 181 | 1.893 | 0.3755 | Yes | ||
6 | CDKN2C | 5050750 5130148 | 210 | 1.819 | 0.4216 | Yes | ||
7 | DDIT4 | 2570408 | 288 | 1.569 | 0.4586 | Yes | ||
8 | GTF2F2 | 2690546 | 482 | 1.146 | 0.4781 | Yes | ||
9 | PIK3R3 | 1770333 | 515 | 1.100 | 0.5052 | Yes | ||
10 | IMPDH2 | 5220138 | 874 | 0.797 | 0.5067 | Yes | ||
11 | PPP1R12C | 580309 4760131 | 1026 | 0.668 | 0.5160 | Yes | ||
12 | H1F0 | 1400408 | 1179 | 0.588 | 0.5232 | Yes | ||
13 | PSME3 | 2810537 | 1319 | 0.530 | 0.5295 | Yes | ||
14 | CYLD | 6590079 | 1543 | 0.439 | 0.5289 | No | ||
15 | DAP3 | 1660528 2120039 5420593 | 1868 | 0.343 | 0.5204 | No | ||
16 | EPHB2 | 1090288 1410377 2100541 | 2761 | 0.157 | 0.4762 | No | ||
17 | RAMP2 | 6860037 | 2851 | 0.146 | 0.4752 | No | ||
18 | SLC16A6 | 1690156 | 3034 | 0.127 | 0.4687 | No | ||
19 | TRAF7 | 1190341 | 3172 | 0.114 | 0.4642 | No | ||
20 | NR3C1 | 630563 | 3215 | 0.110 | 0.4648 | No | ||
21 | STK3 | 7100427 | 3275 | 0.104 | 0.4644 | No | ||
22 | RPL4 | 2940014 5420324 | 3322 | 0.099 | 0.4645 | No | ||
23 | BMP1 | 380594 2940576 3710593 | 3396 | 0.092 | 0.4629 | No | ||
24 | TGIF2 | 3840364 4050520 | 3414 | 0.091 | 0.4644 | No | ||
25 | UQCRC2 | 5550091 | 3452 | 0.089 | 0.4647 | No | ||
26 | EN1 | 5360168 7050025 | 3548 | 0.082 | 0.4617 | No | ||
27 | TNFRSF19 | 3870731 6940730 | 3591 | 0.078 | 0.4615 | No | ||
28 | PPP3CA | 4760332 6760092 | 3770 | 0.066 | 0.4536 | No | ||
29 | NEDD4 | 460736 1190280 | 4015 | 0.053 | 0.4418 | No | ||
30 | MXI1 | 5050064 5130484 | 4107 | 0.049 | 0.4381 | No | ||
31 | PNOC | 1990114 | 4226 | 0.045 | 0.4329 | No | ||
32 | PASK | 7610241 | 4228 | 0.045 | 0.4341 | No | ||
33 | RPS6KB1 | 1450427 5080110 6200563 | 4372 | 0.041 | 0.4274 | No | ||
34 | DPF3 | 2650128 2970168 | 4445 | 0.039 | 0.4245 | No | ||
35 | FOXP2 | 3520561 4150372 4760524 | 4495 | 0.038 | 0.4228 | No | ||
36 | SERPINI1 | 2940468 | 4562 | 0.036 | 0.4202 | No | ||
37 | GLRA1 | 610575 | 4763 | 0.032 | 0.4102 | No | ||
38 | GRIA1 | 1340152 3780750 4920440 | 4957 | 0.028 | 0.4005 | No | ||
39 | PDGFRA | 2940332 | 5037 | 0.027 | 0.3969 | No | ||
40 | TBX2 | 1990563 | 5224 | 0.024 | 0.3875 | No | ||
41 | RAB1A | 2370671 | 5240 | 0.024 | 0.3873 | No | ||
42 | HOXB2 | 6450592 | 5555 | 0.020 | 0.3708 | No | ||
43 | SEMA7A | 2630239 5050593 | 5620 | 0.020 | 0.3679 | No | ||
44 | TENC1 | 1980403 7050575 | 5846 | 0.017 | 0.3562 | No | ||
45 | MYF6 | 2690576 | 5913 | 0.017 | 0.3530 | No | ||
46 | MYL1 | 2450707 | 5995 | 0.016 | 0.3491 | No | ||
47 | CDKN2B | 6020040 | 6158 | 0.015 | 0.3407 | No | ||
48 | TGFBR1 | 1400148 4280020 6550711 | 6555 | 0.012 | 0.3196 | No | ||
49 | RNF14 | 50402 1340041 6370687 | 6572 | 0.012 | 0.3190 | No | ||
50 | FZD9 | 5360136 | 6643 | 0.012 | 0.3155 | No | ||
51 | ABLIM1 | 580170 3710338 6520504 | 6741 | 0.011 | 0.3106 | No | ||
52 | SLC4A10 | 2060670 | 6768 | 0.011 | 0.3094 | No | ||
53 | GPC4 | 5910408 | 6842 | 0.010 | 0.3058 | No | ||
54 | DMC1 | 450341 | 6876 | 0.010 | 0.3042 | No | ||
55 | NHLH2 | 6200021 | 6946 | 0.010 | 0.3008 | No | ||
56 | CXXC5 | 840010 | 7248 | 0.009 | 0.2847 | No | ||
57 | USP15 | 610592 3520504 | 7267 | 0.009 | 0.2839 | No | ||
58 | EYA1 | 1450278 5220390 | 7336 | 0.008 | 0.2805 | No | ||
59 | TNKS1BP1 | 7040184 | 7447 | 0.008 | 0.2747 | No | ||
60 | OBSCN | 3610129 | 7479 | 0.008 | 0.2732 | No | ||
61 | LIN28 | 6590672 | 7554 | 0.007 | 0.2694 | No | ||
62 | KCTD8 | 6660593 | 7799 | 0.006 | 0.2564 | No | ||
63 | IRX4 | 1980102 | 8269 | 0.005 | 0.2311 | No | ||
64 | LHX1 | 1690100 | 8314 | 0.004 | 0.2288 | No | ||
65 | HCN1 | 5130458 | 8379 | 0.004 | 0.2255 | No | ||
66 | HOXD10 | 6100039 | 8634 | 0.003 | 0.2118 | No | ||
67 | FBXO24 | 1230132 4610121 | 8707 | 0.003 | 0.2080 | No | ||
68 | CHRNB3 | 430441 870725 5720204 | 9180 | 0.002 | 0.1824 | No | ||
69 | DNM3 | 730711 | 9191 | 0.002 | 0.1819 | No | ||
70 | WNT2 | 4610020 | 9301 | 0.001 | 0.1761 | No | ||
71 | LBX1 | 1300164 4060204 | 9304 | 0.001 | 0.1760 | No | ||
72 | LRRTM1 | 1690324 | 9435 | 0.001 | 0.1690 | No | ||
73 | BAI3 | 940692 | 9500 | 0.001 | 0.1655 | No | ||
74 | KIAA1715 | 1190551 | 9507 | 0.001 | 0.1652 | No | ||
75 | SPOCK2 | 6650369 | 9522 | 0.001 | 0.1645 | No | ||
76 | BTBD3 | 1980041 2510577 3190053 4200746 | 9536 | 0.000 | 0.1638 | No | ||
77 | GAB2 | 1410280 2340520 4280040 | 9538 | 0.000 | 0.1637 | No | ||
78 | PPP1R7 | 2810148 | 9541 | 0.000 | 0.1636 | No | ||
79 | ACVR1 | 6840671 | 9671 | 0.000 | 0.1567 | No | ||
80 | NXPH4 | 3830500 | 9819 | -0.000 | 0.1487 | No | ||
81 | MAP3K13 | 3190017 | 9941 | -0.001 | 0.1422 | No | ||
82 | CAPZA1 | 3140390 | 9984 | -0.001 | 0.1399 | No | ||
83 | SOST | 1170195 | 10029 | -0.001 | 0.1376 | No | ||
84 | TCF2 | 870338 5050632 | 10112 | -0.001 | 0.1331 | No | ||
85 | KLHL1 | 6350021 | 10412 | -0.002 | 0.1170 | No | ||
86 | HIF1A | 5670605 | 10440 | -0.002 | 0.1156 | No | ||
87 | MAB21L2 | 1770605 | 10527 | -0.003 | 0.1110 | No | ||
88 | CRH | 3710301 | 10535 | -0.003 | 0.1107 | No | ||
89 | KCNQ4 | 3800438 7050400 | 10648 | -0.003 | 0.1047 | No | ||
90 | FRMD3 | 3440731 | 10935 | -0.004 | 0.0893 | No | ||
91 | FOXI1 | 3710095 6620195 | 11052 | -0.004 | 0.0831 | No | ||
92 | MAX | 5220021 | 11143 | -0.005 | 0.0784 | No | ||
93 | EYA2 | 1230070 1780102 | 11303 | -0.005 | 0.0699 | No | ||
94 | NR4A3 | 2900021 5860095 5910039 | 11354 | -0.005 | 0.0673 | No | ||
95 | HOXA2 | 2120121 | 11357 | -0.005 | 0.0674 | No | ||
96 | POU3F3 | 6400047 | 11507 | -0.006 | 0.0594 | No | ||
97 | CLSTN2 | 6900546 | 11784 | -0.007 | 0.0447 | No | ||
98 | CHODL | 7050039 | 11861 | -0.007 | 0.0408 | No | ||
99 | EPHA3 | 2190497 5080059 | 11898 | -0.007 | 0.0390 | No | ||
100 | ELAVL2 | 360181 | 11935 | -0.008 | 0.0372 | No | ||
101 | IRS1 | 1190204 | 12178 | -0.009 | 0.0244 | No | ||
102 | WNT10A | 2100706 | 12191 | -0.009 | 0.0239 | No | ||
103 | CABP5 | 3360273 | 12247 | -0.009 | 0.0212 | No | ||
104 | CAPN6 | 1740168 | 12464 | -0.010 | 0.0098 | No | ||
105 | ABL2 | 580021 | 12675 | -0.011 | -0.0013 | No | ||
106 | LHFP | 3440368 | 12686 | -0.011 | -0.0016 | No | ||
107 | DES | 1450341 | 12687 | -0.011 | -0.0013 | No | ||
108 | UNC13B | 130735 | 12772 | -0.012 | -0.0055 | No | ||
109 | APBA1 | 3140487 | 12843 | -0.012 | -0.0090 | No | ||
110 | ONECUT2 | 1340008 | 12960 | -0.013 | -0.0149 | No | ||
111 | ST7L | 840735 2360576 | 13101 | -0.014 | -0.0221 | No | ||
112 | ADCY8 | 6760519 | 13215 | -0.015 | -0.0278 | No | ||
113 | GPHN | 3290195 3840121 | 13269 | -0.016 | -0.0303 | No | ||
114 | DYSF | 4670411 | 13496 | -0.018 | -0.0420 | No | ||
115 | NPPA | 6550328 | 13790 | -0.022 | -0.0573 | No | ||
116 | AHR | 4560671 | 13817 | -0.022 | -0.0582 | No | ||
117 | NOL4 | 5050446 5360519 | 13842 | -0.023 | -0.0589 | No | ||
118 | RFX3 | 520121 4280519 5570519 6100184 | 13888 | -0.023 | -0.0607 | No | ||
119 | ASH1L | 2510402 5360687 6650685 | 13915 | -0.024 | -0.0615 | No | ||
120 | FKBP3 | 5050605 | 14143 | -0.028 | -0.0730 | No | ||
121 | JPH1 | 610739 | 14329 | -0.032 | -0.0822 | No | ||
122 | CALCRL | 4280035 | 14331 | -0.032 | -0.0815 | No | ||
123 | APOBEC2 | 1690520 | 14394 | -0.033 | -0.0839 | No | ||
124 | SPRED1 | 6940706 | 14867 | -0.048 | -0.1082 | No | ||
125 | THRAP1 | 2470121 | 15000 | -0.054 | -0.1140 | No | ||
126 | NLK | 2030010 2450041 | 15198 | -0.067 | -0.1229 | No | ||
127 | ALDOC | 450121 610427 | 15231 | -0.069 | -0.1228 | No | ||
128 | NRGN | 4280433 | 15326 | -0.075 | -0.1260 | No | ||
129 | GPR156 | 6350609 6900079 | 15413 | -0.082 | -0.1285 | No | ||
130 | LRCH4 | 5220279 6510026 | 15473 | -0.089 | -0.1294 | No | ||
131 | TUBB4 | 5310681 | 15627 | -0.102 | -0.1350 | No | ||
132 | SORT1 | 1850242 2320632 3870537 | 15664 | -0.106 | -0.1341 | No | ||
133 | TAF5 | 3450288 5890193 6860435 | 15767 | -0.117 | -0.1366 | No | ||
134 | MAP2K5 | 2030440 | 16064 | -0.156 | -0.1485 | No | ||
135 | CACNB3 | 2480035 4540184 | 16065 | -0.157 | -0.1444 | No | ||
136 | ACADSB | 520170 | 16145 | -0.170 | -0.1443 | No | ||
137 | SLC25A12 | 7400731 | 16231 | -0.182 | -0.1441 | No | ||
138 | ESRRA | 6550242 | 16407 | -0.211 | -0.1481 | No | ||
139 | AEBP2 | 2970603 | 16442 | -0.219 | -0.1442 | No | ||
140 | COL7A1 | 1230168 2190072 | 16613 | -0.250 | -0.1469 | No | ||
141 | CTCF | 5340017 | 16777 | -0.280 | -0.1484 | No | ||
142 | VAMP8 | 380411 1190139 | 16807 | -0.288 | -0.1424 | No | ||
143 | SLC12A2 | 4610019 6040672 | 16851 | -0.301 | -0.1369 | No | ||
144 | ITCH | 1410731 5700022 | 17025 | -0.346 | -0.1372 | No | ||
145 | SLC23A2 | 6660722 | 17061 | -0.357 | -0.1297 | No | ||
146 | WARS | 2570717 3290139 | 17084 | -0.367 | -0.1213 | No | ||
147 | DDX6 | 2630025 6770408 | 17219 | -0.421 | -0.1175 | No | ||
148 | TLK2 | 1170161 | 17304 | -0.456 | -0.1101 | No | ||
149 | DNAJB5 | 2900215 | 17717 | -0.653 | -0.1153 | No | ||
150 | SOX4 | 2260091 | 17765 | -0.693 | -0.0997 | No | ||
151 | DCTN1 | 1450056 6590022 | 17780 | -0.703 | -0.0821 | No | ||
152 | MAP1LC3B | 730142 | 17786 | -0.705 | -0.0639 | No | ||
153 | SESN1 | 2120021 | 18117 | -1.029 | -0.0548 | No | ||
154 | TRAF3 | 5690647 | 18242 | -1.233 | -0.0292 | No | ||
155 | KCNH2 | 1170451 | 18445 | -1.887 | 0.0093 | No |