Details for gene set V$SMAD4

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	wtNotch
GeneSet	V$SMAD4_Q6
Enrichment Score (ES)	0.5297601
Normalized Enrichment Score (NES)	1.2745283
Nominal p-value	0.049152542
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	EEF1A1	1980193 1990195 4670735	0	9.007	0.1714	Yes
2	ARID1A	2630022 1690551 4810110	3	6.330	0.2917	Yes
3	MCRS1	110121 2340592 5270484	42	3.506	0.3564	Yes
4	PCBP4	6350722	49	3.258	0.4181	Yes
5	NSBP1	2260427	483	1.143	0.4163	Yes
6	POU2AF1	5690242	567	1.036	0.4316	Yes
7	SFRS6	60224	699	0.926	0.4421	Yes
8	EIF4A1	1990341 2810300	806	0.852	0.4526	Yes
9	ATP2A2	1090075 3990279	812	0.849	0.4684	Yes
10	UBE4B	780008 3610154	852	0.812	0.4818	Yes
11	OTX2	1190471	999	0.685	0.4869	Yes
12	HYAL2	1500152	1034	0.665	0.4977	Yes
13	PSMC5	2760315 6550021	1127	0.610	0.5043	Yes
14	HOXB1	2120110	1273	0.548	0.5069	Yes
15	POLR2I	4060400	1307	0.535	0.5153	Yes
16	GDF1	2350132	1495	0.458	0.5139	Yes
17	NOTCH3	3060603	1514	0.451	0.5215	Yes
18	FKBP10	1340706	1733	0.381	0.5169	Yes
19	TNFRSF12A	4810253	1794	0.364	0.5206	Yes
20	LMO4	3800746	1841	0.351	0.5248	Yes
21	VAPA	2480594	1974	0.316	0.5237	Yes
22	UBE2E1	4230064 1090440	1985	0.313	0.5291	Yes
23	RPS6KA3	1980707	2107	0.281	0.5279	Yes
24	CASKIN2	2030113	2193	0.262	0.5282	Yes
25	TBX6	4730139 6840647	2295	0.237	0.5273	Yes
26	TCF4	520021	2331	0.231	0.5298	Yes
27	RPS8	4120136	2465	0.204	0.5264	No
28	PBX3	1300424 3710577 6180575	2632	0.175	0.5208	No
29	PRKAG1	6450091	3107	0.120	0.4974	No
30	TRPS1	870100	3123	0.118	0.4988	No
31	PRKCZ	3780279	3157	0.115	0.4992	No
32	RALA	2680471	3168	0.114	0.5009	No
33	AP2M1	2570338	3188	0.112	0.5020	No
34	PFN2	730040 5700026	3403	0.092	0.4921	No
35	MMP11	1980619	3465	0.088	0.4905	No
36	AMMECR1	3800435	3568	0.080	0.4865	No
37	PPP3CA	4760332 6760092	3770	0.066	0.4768	No
38	SLC22A17	540452 4200253	3841	0.062	0.4742	No
39	SSBP3	870717 1050377 7040551	3872	0.061	0.4738	No
40	THRA	6770341 110164 1990600	3973	0.056	0.4694	No
41	NR2F1	4120528 360402	3999	0.054	0.4691	No
42	TMEM25	2470575 2570400	4098	0.050	0.4647	No
43	FASTK	2690053 4280288 4610551 6370292	4128	0.049	0.4641	No
44	DHX40	360672	4232	0.045	0.4594	No
45	KCTD15	2810735	4331	0.042	0.4549	No
46	COL1A2	380364	4477	0.038	0.4477	No
47	ACACA	2490612 2680369	4648	0.034	0.4392	No
48	COL25A1	1580072 4280537 4480168 5290441 7040563	4658	0.034	0.4393	No
49	HOXA9	610494 4730040 5130601	4660	0.034	0.4399	No
50	AVP	2100113	4766	0.032	0.4348	No
51	PDGFRA	2940332	5037	0.027	0.4207	No
52	ARHGEF19	940102	5080	0.026	0.4189	No
53	NR1D1	2360471 770746 6590204	5178	0.025	0.4141	No
54	KIRREL3	2630195	5327	0.023	0.4066	No
55	TRIM3	5570156	5397	0.022	0.4032	No
56	HOXA3	3610632 6020358	5425	0.022	0.4022	No
57	WNT1	4780148	5605	0.020	0.3929	No
58	CREB1	1500717 2230358 3610600 6550601	5622	0.020	0.3924	No
59	TENC1	1980403 7050575	5846	0.017	0.3806	No
60	CLOCK	1410070 2940292 3390075	5935	0.017	0.3762	No
61	SULF1	430575	5945	0.017	0.3760	No
62	LAMC2	450692 2680041 4200059 4670148	6011	0.016	0.3728	No
63	DACH2	460605 1500253	6314	0.014	0.3567	No
64	HOXA10	6110397 7100458	6442	0.013	0.3501	No
65	NXPH3	5860292	6575	0.012	0.3432	No
66	SP8	4060576	6627	0.012	0.3406	No
67	PHF8	70722	6718	0.011	0.3360	No
68	LMO1	3170528	6765	0.011	0.3337	No
69	ADAMTS4	430435	6829	0.011	0.3305	No
70	NTF5	6110239	6955	0.010	0.3239	No
71	PURA	3870156	7035	0.010	0.3198	No
72	IL17RC	630164 2810593	7270	0.008	0.3073	No
73	FGF4	6550528	7333	0.008	0.3041	No
74	DOK1	1050279 2680112 5220273	7620	0.007	0.2887	No
75	SLC12A5	1980692	7708	0.007	0.2841	No
76	WNT3	2360685	7844	0.006	0.2769	No
77	AKAP4	2190731 3520619	7937	0.006	0.2720	No
78	SST	6590142	8056	0.005	0.2657	No
79	POU4F3	2690035	8313	0.004	0.2520	No
80	SDR-O	840273 780592 5570537 5900309	8450	0.004	0.2447	No
81	IL23A	6290044	8510	0.004	0.2415	No
82	CALD1	1770129 1940397	8553	0.004	0.2393	No
83	ADORA2B	6860253	8604	0.003	0.2367	No
84	LGI1	1850020	8832	0.003	0.2244	No
85	CALM1	380128	8853	0.003	0.2234	No
86	CHRM1	4280619	9256	0.001	0.2017	No
87	CXADR	6370068	9275	0.001	0.2007	No
88	CACNG3	520093	9732	-0.000	0.1760	No
89	ATP6V1E2	6840706	10028	-0.001	0.1600	No
90	SUV39H2	1450672 6370242	10128	-0.001	0.1547	No
91	PTBP2	1240398	10138	-0.001	0.1542	No
92	RHOQ	520161	10146	-0.001	0.1539	No
93	PAK3	4210136	10424	-0.002	0.1389	No
94	LASS1	3440746 6110152	10563	-0.003	0.1315	No
95	CACNA1G	3060161 4810706 5550722	10720	-0.003	0.1231	No
96	ABCA1	6290156	10872	-0.004	0.1150	No
97	EPHB1	4610056	10898	-0.004	0.1137	No
98	EVX1	1980471	10932	-0.004	0.1120	No
99	CDH13	5130368 5340114	10944	-0.004	0.1115	No
100	LOXL3	4010168	10949	-0.004	0.1113	No
101	MAFB	1230471	11001	-0.004	0.1086	No
102	FGF16	4210440	11043	-0.004	0.1065	No
103	FOXI1	3710095 6620195	11052	-0.004	0.1061	No
104	ADAMTSL1	2970092	11115	-0.004	0.1029	No
105	NTRK3	4050687 4070167 4610026 6100484	11196	-0.005	0.0986	No
106	FLRT1	4540348	11390	-0.005	0.0883	No
107	WDR13	3840520 4670064	11573	-0.006	0.0785	No
108	LHB	1450368	11632	-0.006	0.0755	No
109	NFATC4	2470735	11722	-0.007	0.0708	No
110	DLGAP4	4570672 5690161	11737	-0.007	0.0702	No
111	TBX5	2900132 6370484	11744	-0.007	0.0700	No
112	DSCR1	4540048 6220039	11835	-0.007	0.0652	No
113	IRS1	1190204	12178	-0.009	0.0469	No
114	BNC2	4810603	12209	-0.009	0.0454	No
115	MEF2C	670025 780338	12418	-0.010	0.0343	No
116	PLEC1	6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471	12482	-0.010	0.0311	No
117	AGER	5860538 5910180	12580	-0.011	0.0261	No
118	DHRS3	360609	12770	-0.012	0.0160	No
119	PLA2G2F	3190646	12954	-0.013	0.0064	No
120	EPHA2	5890056	13415	-0.017	-0.0182	No
121	KCNN2	990025 3520524	13556	-0.019	-0.0255	No
122	LHX4	6940551	13625	-0.020	-0.0288	No
123	HOXA6	2340333	13812	-0.022	-0.0384	No
124	ETV4	2450605	13983	-0.025	-0.0472	No
125	PPM2C	3360209	14148	-0.028	-0.0555	No
126	FMO2	3850338	14303	-0.031	-0.0633	No
127	RGS3	60670 540736 1340180 1500369 3390735 4010131 4610402 6380114	14506	-0.035	-0.0735	No
128	MYLK	4010600 7000364	14743	-0.043	-0.0855	No
129	FOXB1	4920270 5290463	15059	-0.058	-0.1015	No
130	CDK6	4920253	15139	-0.062	-0.1046	No
131	APBB1	2690338	15454	-0.086	-0.1199	No
132	HNRPUL1	2120008 4920408 5570180 6370609 6770403	15608	-0.101	-0.1263	No
133	GNB2	2350053	15749	-0.115	-0.1317	No
134	RORA	380164 5220215	15921	-0.137	-0.1384	No
135	ELOVL5	3800170	15946	-0.140	-0.1370	No
136	VDR	130156 510438	16112	-0.164	-0.1428	No
137	HNRPK	1190348 2060411 2570092 6840551	16256	-0.185	-0.1471	No
138	CRK	1230162 4780128	16356	-0.203	-0.1486	No
139	SIPA1	5220687	16478	-0.225	-0.1509	No
140	HHEX	2340575	16533	-0.235	-0.1493	No
141	USP2	1190292 1240253 4850035	16553	-0.238	-0.1458	No
142	PPP3CB	6020156	16598	-0.248	-0.1435	No
143	FLI1	3990142	16746	-0.273	-0.1462	No
144	NFKB2	2320670	16848	-0.300	-0.1460	No
145	YPEL1	6590435	16994	-0.337	-0.1474	No
146	NAB2	1570014	17056	-0.357	-0.1439	No
147	LDB1	5270601	17164	-0.395	-0.1422	No
148	SLC25A14	4760180	17263	-0.438	-0.1392	No
149	SNX12	4060026	17266	-0.439	-0.1309	No
150	TRIM8	6130441	17475	-0.533	-0.1321	No
151	POLD4	2320082	17512	-0.550	-0.1236	No
152	PHF12	870400 3130687	17745	-0.678	-0.1232	No
153	DCTN1	1450056 6590022	17780	-0.703	-0.1117	No
154	PAX1	3360253	17805	-0.722	-0.0993	No
155	GBA2	2900372	17912	-0.795	-0.0899	No
156	WASF2	4850592	17913	-0.797	-0.0747	No
157	DIABLO	2360170	17935	-0.815	-0.0604	No
158	FBS1	2570520	18100	-1.002	-0.0502	No
159	KLF7	50390	18236	-1.223	-0.0342	No
160	TRAF3	5690647	18242	-1.233	-0.0110	No
161	EPC1	1570050 5290095 6900193	18382	-1.642	0.0127	No