Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$NMYC_01 |
Enrichment Score (ES) | 0.6228385 |
Normalized Enrichment Score (NES) | 1.5124308 |
Nominal p-value | 0.0 |
FDR q-value | 0.5035021 |
FWER p-Value | 0.824 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 6 | 5.043 | 0.0864 | Yes | ||
2 | TIMM10 | 610070 1450019 | 20 | 4.600 | 0.1647 | Yes | ||
3 | PABPC4 | 1990170 6760270 5390138 | 33 | 3.900 | 0.2311 | Yes | ||
4 | HMOX1 | 1740687 | 92 | 2.622 | 0.2731 | Yes | ||
5 | VARS2 | 1410017 3800114 4210270 | 252 | 1.705 | 0.2937 | Yes | ||
6 | CEBPB | 2970019 | 282 | 1.602 | 0.3197 | Yes | ||
7 | ATAD3A | 4050288 | 328 | 1.448 | 0.3422 | Yes | ||
8 | HSPD1 | 60097 2030451 | 334 | 1.441 | 0.3667 | Yes | ||
9 | SH3KBP1 | 670102 2850458 7000309 | 415 | 1.267 | 0.3841 | Yes | ||
10 | IPO4 | 5050619 | 419 | 1.251 | 0.4055 | Yes | ||
11 | FBL | 5130020 | 420 | 1.249 | 0.4269 | Yes | ||
12 | PRDX4 | 3800039 | 440 | 1.206 | 0.4466 | Yes | ||
13 | G6PC3 | 1580487 5390253 | 540 | 1.061 | 0.4595 | Yes | ||
14 | VPS16 | 430064 3390041 6860301 | 630 | 0.976 | 0.4715 | Yes | ||
15 | DLX1 | 360168 | 662 | 0.950 | 0.4861 | Yes | ||
16 | ATP5G1 | 5290019 | 729 | 0.902 | 0.4980 | Yes | ||
17 | PPAT | 1980019 | 740 | 0.895 | 0.5129 | Yes | ||
18 | PA2G4 | 2030463 | 742 | 0.894 | 0.5282 | Yes | ||
19 | BCL7C | 460050 | 895 | 0.776 | 0.5333 | Yes | ||
20 | FKBP5 | 2190048 | 952 | 0.716 | 0.5426 | Yes | ||
21 | HYAL2 | 1500152 | 1034 | 0.665 | 0.5496 | Yes | ||
22 | HMGN2 | 3140091 | 1250 | 0.558 | 0.5475 | Yes | ||
23 | EIF4B | 5390563 5270577 | 1274 | 0.548 | 0.5557 | Yes | ||
24 | LMNB1 | 5890292 6020008 | 1375 | 0.508 | 0.5590 | Yes | ||
25 | NOL5A | 5570139 | 1376 | 0.507 | 0.5677 | Yes | ||
26 | GPD1 | 2480095 | 1435 | 0.484 | 0.5729 | Yes | ||
27 | HSPE1 | 3170438 | 1661 | 0.403 | 0.5676 | Yes | ||
28 | COPS7A | 3940458 7000022 | 1668 | 0.401 | 0.5742 | Yes | ||
29 | RPL22 | 4070070 | 1675 | 0.397 | 0.5807 | Yes | ||
30 | PES1 | 2470427 | 1731 | 0.382 | 0.5843 | Yes | ||
31 | FKBP10 | 1340706 | 1733 | 0.381 | 0.5908 | Yes | ||
32 | SRP72 | 3990427 | 1789 | 0.367 | 0.5941 | Yes | ||
33 | ELOVL6 | 5340746 | 1814 | 0.358 | 0.5989 | Yes | ||
34 | POLR3E | 380152 | 1855 | 0.347 | 0.6027 | Yes | ||
35 | LIG3 | 2940300 | 1864 | 0.344 | 0.6082 | Yes | ||
36 | GTPBP1 | 2230541 4560528 | 1879 | 0.340 | 0.6133 | Yes | ||
37 | ZCCHC7 | 6510592 | 1934 | 0.326 | 0.6160 | Yes | ||
38 | ANXA6 | 2190014 | 1991 | 0.311 | 0.6183 | Yes | ||
39 | EIF4G1 | 4070446 | 2065 | 0.292 | 0.6193 | Yes | ||
40 | FHOD1 | 2680279 | 2097 | 0.283 | 0.6225 | Yes | ||
41 | KRTCAP2 | 5220040 | 2177 | 0.267 | 0.6228 | Yes | ||
42 | GADD45G | 2510142 | 2606 | 0.179 | 0.6027 | No | ||
43 | MYST3 | 5270500 | 2753 | 0.158 | 0.5975 | No | ||
44 | TLE3 | 580040 4730121 | 2826 | 0.149 | 0.5962 | No | ||
45 | RAMP2 | 6860037 | 2851 | 0.146 | 0.5974 | No | ||
46 | CACNA1D | 1740315 4730731 | 2891 | 0.140 | 0.5976 | No | ||
47 | PSEN2 | 130382 | 2901 | 0.139 | 0.5995 | No | ||
48 | PPARGC1B | 3290114 | 2930 | 0.136 | 0.6004 | No | ||
49 | CDC14A | 4050132 | 2962 | 0.133 | 0.6010 | No | ||
50 | B4GALT2 | 780037 | 3150 | 0.115 | 0.5928 | No | ||
51 | DUSP4 | 2690044 2850593 | 3175 | 0.113 | 0.5935 | No | ||
52 | UBE1 | 4150139 7050463 | 3187 | 0.112 | 0.5948 | No | ||
53 | RBBP6 | 2320129 | 3332 | 0.098 | 0.5887 | No | ||
54 | MAPKAPK3 | 630520 | 3350 | 0.097 | 0.5894 | No | ||
55 | TIMM9 | 2450484 | 3376 | 0.094 | 0.5897 | No | ||
56 | NR5A1 | 70707 | 3404 | 0.092 | 0.5898 | No | ||
57 | KCNK5 | 4590504 6860687 | 3589 | 0.078 | 0.5812 | No | ||
58 | RUNX2 | 1400193 4230215 | 3699 | 0.070 | 0.5765 | No | ||
59 | AMPD2 | 630093 1170070 | 3769 | 0.066 | 0.5738 | No | ||
60 | BAI2 | 380632 630113 6650170 | 3902 | 0.059 | 0.5677 | No | ||
61 | CTBP2 | 430309 3710079 | 3917 | 0.059 | 0.5680 | No | ||
62 | ARRDC3 | 4610390 | 4077 | 0.051 | 0.5602 | No | ||
63 | RAD9A | 110300 1940632 3990390 6040014 | 4082 | 0.050 | 0.5609 | No | ||
64 | PANK3 | 3060687 | 4092 | 0.050 | 0.5612 | No | ||
65 | TIAL1 | 4150048 6510605 | 4191 | 0.046 | 0.5567 | No | ||
66 | SOX12 | 1780037 | 4369 | 0.041 | 0.5478 | No | ||
67 | ADPRHL1 | 4150133 6650300 | 4516 | 0.037 | 0.5405 | No | ||
68 | RCL1 | 1980408 2680008 3800176 | 4561 | 0.036 | 0.5388 | No | ||
69 | SOCS5 | 3830398 7100093 | 4649 | 0.034 | 0.5346 | No | ||
70 | NR1D1 | 2360471 770746 6590204 | 5178 | 0.025 | 0.5064 | No | ||
71 | NRXN1 | 460408 5340270 6370066 | 5179 | 0.025 | 0.5069 | No | ||
72 | ANGPT2 | 1230458 5720706 6040605 | 5242 | 0.024 | 0.5039 | No | ||
73 | TESK2 | 6520524 | 5352 | 0.023 | 0.4984 | No | ||
74 | SEMA7A | 2630239 5050593 | 5620 | 0.020 | 0.4843 | No | ||
75 | GPC3 | 6180735 | 5671 | 0.019 | 0.4819 | No | ||
76 | HS3ST3A1 | 2230497 | 6008 | 0.016 | 0.4639 | No | ||
77 | XRN2 | 130603 1230113 4230309 | 6018 | 0.016 | 0.4637 | No | ||
78 | COL2A1 | 460446 3940500 | 6245 | 0.014 | 0.4517 | No | ||
79 | SC5DL | 6650390 | 6468 | 0.013 | 0.4399 | No | ||
80 | TPM2 | 520735 3870390 | 6735 | 0.011 | 0.4257 | No | ||
81 | NXPH1 | 3870546 | 6751 | 0.011 | 0.4250 | No | ||
82 | RTN4RL2 | 6450609 | 6893 | 0.010 | 0.4176 | No | ||
83 | SGTB | 460170 | 6903 | 0.010 | 0.4172 | No | ||
84 | EN2 | 7000368 | 6984 | 0.010 | 0.4131 | No | ||
85 | KIAA0427 | 1690435 | 7079 | 0.009 | 0.4081 | No | ||
86 | DNAJB9 | 460114 | 7148 | 0.009 | 0.4046 | No | ||
87 | ETV1 | 70735 2940603 5080463 | 7354 | 0.008 | 0.3936 | No | ||
88 | PLA2G4A | 6380364 | 7420 | 0.008 | 0.3902 | No | ||
89 | LIN28 | 6590672 | 7554 | 0.007 | 0.3832 | No | ||
90 | AKAP10 | 2630504 5910577 | 7651 | 0.007 | 0.3781 | No | ||
91 | SLC12A5 | 1980692 | 7708 | 0.007 | 0.3751 | No | ||
92 | DNMT3A | 4050068 4810717 | 7784 | 0.006 | 0.3712 | No | ||
93 | RNF128 | 1230300 5670273 | 7817 | 0.006 | 0.3696 | No | ||
94 | POGK | 5290315 | 7932 | 0.006 | 0.3635 | No | ||
95 | SLC38A5 | 540093 | 8155 | 0.005 | 0.3515 | No | ||
96 | HOXC13 | 4070722 | 8182 | 0.005 | 0.3502 | No | ||
97 | BMP2K | 60541 5570504 | 8205 | 0.005 | 0.3491 | No | ||
98 | NRAS | 6900577 | 8451 | 0.004 | 0.3359 | No | ||
99 | GRIN2A | 6550538 | 8554 | 0.004 | 0.3304 | No | ||
100 | NKX2-2 | 4150731 | 8820 | 0.003 | 0.3161 | No | ||
101 | FGF11 | 840292 | 8843 | 0.003 | 0.3149 | No | ||
102 | ADAM10 | 3780156 | 8850 | 0.003 | 0.3147 | No | ||
103 | PCDHA10 | 3830725 | 8977 | 0.002 | 0.3079 | No | ||
104 | B3GALT2 | 430136 | 9020 | 0.002 | 0.3056 | No | ||
105 | NUP153 | 7000452 | 9036 | 0.002 | 0.3048 | No | ||
106 | SLC17A2 | 870593 2810035 | 9153 | 0.002 | 0.2986 | No | ||
107 | CHRM1 | 4280619 | 9256 | 0.001 | 0.2931 | No | ||
108 | LAP3 | 2570064 | 9786 | -0.000 | 0.2644 | No | ||
109 | CTSF | 6100021 | 9893 | -0.001 | 0.2586 | No | ||
110 | MTHFD1 | 5900398 6520427 | 10571 | -0.003 | 0.2220 | No | ||
111 | ALX4 | 3870019 | 10656 | -0.003 | 0.2175 | No | ||
112 | GPS1 | 2470037 4760315 6200528 7100040 | 10659 | -0.003 | 0.2174 | No | ||
113 | STMN4 | 2900091 | 10727 | -0.003 | 0.2138 | No | ||
114 | LHX9 | 2350112 | 10869 | -0.004 | 0.2062 | No | ||
115 | ABCA1 | 6290156 | 10872 | -0.004 | 0.2062 | No | ||
116 | ENPP6 | 110524 580563 | 10940 | -0.004 | 0.2026 | No | ||
117 | BARHL1 | 4210113 | 11107 | -0.004 | 0.1937 | No | ||
118 | MAX | 5220021 | 11143 | -0.005 | 0.1919 | No | ||
119 | PRKCE | 5700053 | 11223 | -0.005 | 0.1877 | No | ||
120 | APOA5 | 6130471 | 11405 | -0.006 | 0.1780 | No | ||
121 | EIF3S1 | 6130368 6770044 | 11678 | -0.006 | 0.1633 | No | ||
122 | NEUROD2 | 5290097 | 11795 | -0.007 | 0.1571 | No | ||
123 | SEPT3 | 3830022 5290079 | 11806 | -0.007 | 0.1567 | No | ||
124 | HPCA | 6860010 | 11854 | -0.007 | 0.1543 | No | ||
125 | NPM1 | 4730427 | 11860 | -0.007 | 0.1542 | No | ||
126 | FLT3 | 2640487 | 12159 | -0.009 | 0.1381 | No | ||
127 | SFXN2 | 2650563 3140095 3830762 3870398 | 12362 | -0.010 | 0.1273 | No | ||
128 | NEUROD6 | 4670731 | 12492 | -0.010 | 0.1205 | No | ||
129 | SCFD2 | 2480504 | 12596 | -0.011 | 0.1151 | No | ||
130 | NDUFS1 | 2650253 | 12667 | -0.011 | 0.1115 | No | ||
131 | PLAG1 | 1450142 3870139 6520039 | 12912 | -0.013 | 0.0985 | No | ||
132 | WEE1 | 3390070 | 13018 | -0.014 | 0.0931 | No | ||
133 | IPO13 | 3870088 | 13106 | -0.014 | 0.0886 | No | ||
134 | POU3F1 | 3710022 | 13314 | -0.016 | 0.0776 | No | ||
135 | HHIP | 6940438 | 13385 | -0.017 | 0.0741 | No | ||
136 | ADAMTS17 | 6510739 | 13463 | -0.018 | 0.0703 | No | ||
137 | SNCAIP | 4010551 | 13516 | -0.018 | 0.0678 | No | ||
138 | CHST11 | 6760546 | 13531 | -0.018 | 0.0673 | No | ||
139 | PLAGL1 | 3190082 6200193 | 13618 | -0.019 | 0.0630 | No | ||
140 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 13796 | -0.022 | 0.0538 | No | ||
141 | CUGBP1 | 450292 510022 7050176 7050215 | 13867 | -0.023 | 0.0504 | No | ||
142 | DLC1 | 1090632 6450594 | 13911 | -0.024 | 0.0484 | No | ||
143 | JPH1 | 610739 | 14329 | -0.032 | 0.0264 | No | ||
144 | MCM8 | 6130743 | 14349 | -0.032 | 0.0259 | No | ||
145 | HRH3 | 6180040 | 14504 | -0.035 | 0.0181 | No | ||
146 | CLCN2 | 1940021 | 14536 | -0.036 | 0.0171 | No | ||
147 | HOXB7 | 4540706 4610358 | 14570 | -0.037 | 0.0159 | No | ||
148 | ADCY3 | 2350347 3440242 | 14619 | -0.039 | 0.0140 | No | ||
149 | RPL13A | 2680519 5700142 | 14717 | -0.042 | 0.0095 | No | ||
150 | ZHX2 | 2900452 | 14917 | -0.051 | -0.0005 | No | ||
151 | U2AF2 | 450600 4670128 5420292 | 15431 | -0.084 | -0.0268 | No | ||
152 | SEMA3F | 5420601 6770731 | 15538 | -0.093 | -0.0310 | No | ||
153 | SCYL1 | 5050717 | 15861 | -0.129 | -0.0462 | No | ||
154 | GRK6 | 1500053 | 15906 | -0.135 | -0.0463 | No | ||
155 | MNT | 4920575 | 16026 | -0.150 | -0.0502 | No | ||
156 | RXRB | 1780040 5340438 | 16248 | -0.183 | -0.0590 | No | ||
157 | HRSP12 | 610136 2510133 4280561 2760047 | 16262 | -0.186 | -0.0565 | No | ||
158 | ATP6V0B | 2810112 | 16367 | -0.204 | -0.0586 | No | ||
159 | PFKFB3 | 630706 | 16409 | -0.212 | -0.0572 | No | ||
160 | TOP1 | 770471 4060632 6650324 | 16424 | -0.215 | -0.0543 | No | ||
161 | USP2 | 1190292 1240253 4850035 | 16553 | -0.238 | -0.0571 | No | ||
162 | PDK2 | 2690017 | 16570 | -0.243 | -0.0538 | No | ||
163 | MXD4 | 4810113 | 16630 | -0.252 | -0.0527 | No | ||
164 | GNA13 | 4590102 | 16639 | -0.254 | -0.0487 | No | ||
165 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16684 | -0.261 | -0.0466 | No | ||
166 | GADD45B | 2350408 | 16698 | -0.265 | -0.0428 | No | ||
167 | ARF6 | 3520026 | 16734 | -0.270 | -0.0400 | No | ||
168 | RBM3 | 2360739 5700167 | 16766 | -0.277 | -0.0370 | No | ||
169 | PFN1 | 6130132 | 17047 | -0.354 | -0.0461 | No | ||
170 | SLC20A1 | 6420014 | 17083 | -0.367 | -0.0416 | No | ||
171 | HTF9C | 3190048 4120132 | 17477 | -0.533 | -0.0538 | No | ||
172 | TEF | 1050050 3120397 4060487 | 17678 | -0.631 | -0.0538 | No | ||
173 | AP1GBP1 | 2510372 | 17744 | -0.677 | -0.0457 | No | ||
174 | GJA1 | 5220731 | 17809 | -0.725 | -0.0367 | No | ||
175 | STAT3 | 460040 3710341 | 17921 | -0.802 | -0.0289 | No | ||
176 | RPIA | 780079 | 17995 | -0.863 | -0.0180 | No | ||
177 | WBP2 | 3170128 | 18224 | -1.201 | -0.0097 | No | ||
178 | HBP1 | 2510102 3130010 4210619 | 18428 | -1.800 | 0.0102 | No |