Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$NKX61_01 |
Enrichment Score (ES) | -0.6083646 |
Normalized Enrichment Score (NES) | -1.5580044 |
Nominal p-value | 0.0 |
FDR q-value | 0.13336867 |
FWER p-Value | 0.513 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LMNA | 520471 1500075 3190167 4210020 | 279 | 1.616 | 0.0289 | No | ||
2 | WNT8B | 4560301 | 438 | 1.211 | 0.0534 | No | ||
3 | CUL3 | 1850520 | 579 | 1.029 | 0.0739 | No | ||
4 | ATP2A2 | 1090075 3990279 | 812 | 0.849 | 0.0845 | No | ||
5 | CXCL13 | 6290402 | 919 | 0.751 | 0.0992 | No | ||
6 | MBNL2 | 3450707 | 1669 | 0.400 | 0.0695 | No | ||
7 | TCF4 | 520021 | 2331 | 0.231 | 0.0400 | No | ||
8 | VAMP3 | 7100050 | 2425 | 0.212 | 0.0408 | No | ||
9 | TYRO3 | 3130193 | 2599 | 0.180 | 0.0363 | No | ||
10 | NTNG2 | 1770438 6380408 | 2611 | 0.179 | 0.0406 | No | ||
11 | ZADH2 | 520438 | 2797 | 0.153 | 0.0347 | No | ||
12 | DTNA | 1340600 1780731 2340278 2850132 | 2919 | 0.137 | 0.0319 | No | ||
13 | STOML2 | 1940487 | 3023 | 0.128 | 0.0298 | No | ||
14 | PLRG1 | 4480735 | 3027 | 0.128 | 0.0331 | No | ||
15 | PRKAG1 | 6450091 | 3107 | 0.120 | 0.0321 | No | ||
16 | CDC2L2 | 1400671 5290168 | 3224 | 0.109 | 0.0288 | No | ||
17 | HOXC6 | 3850133 4920736 | 3257 | 0.106 | 0.0299 | No | ||
18 | TBXAS1 | 5050053 6900286 | 3397 | 0.092 | 0.0249 | No | ||
19 | RNF4 | 580286 1400152 | 3474 | 0.087 | 0.0232 | No | ||
20 | EN1 | 5360168 7050025 | 3548 | 0.082 | 0.0215 | No | ||
21 | NSD1 | 4560519 4780672 | 3560 | 0.081 | 0.0231 | No | ||
22 | AMMECR1 | 3800435 | 3568 | 0.080 | 0.0249 | No | ||
23 | NCOR1 | 3710132 | 3703 | 0.070 | 0.0195 | No | ||
24 | SESN3 | 110687 | 3813 | 0.063 | 0.0153 | No | ||
25 | SSBP3 | 870717 1050377 7040551 | 3872 | 0.061 | 0.0139 | No | ||
26 | HESX1 | 4050746 | 3890 | 0.060 | 0.0146 | No | ||
27 | ERG | 50154 1770739 | 3953 | 0.057 | 0.0127 | No | ||
28 | NR2F1 | 4120528 360402 | 3999 | 0.054 | 0.0118 | No | ||
29 | DSG4 | 3990605 6400736 | 4045 | 0.052 | 0.0108 | No | ||
30 | A2BP1 | 2370390 4590593 5550014 | 4218 | 0.046 | 0.0027 | No | ||
31 | AOC2 | 520348 3120008 | 4230 | 0.045 | 0.0033 | No | ||
32 | HABP2 | 5360541 6350273 | 4307 | 0.043 | 0.0004 | No | ||
33 | FOXP2 | 3520561 4150372 4760524 | 4495 | 0.038 | -0.0087 | No | ||
34 | MID1 | 4070114 4760458 | 4520 | 0.037 | -0.0090 | No | ||
35 | ERMAP | 780156 | 4723 | 0.033 | -0.0191 | No | ||
36 | ZRANB1 | 510373 4540278 | 4738 | 0.032 | -0.0190 | No | ||
37 | PDGFRA | 2940332 | 5037 | 0.027 | -0.0344 | No | ||
38 | UBE2C | 6130017 | 5140 | 0.025 | -0.0392 | No | ||
39 | OTP | 2630070 | 5153 | 0.025 | -0.0392 | No | ||
40 | ANGPT2 | 1230458 5720706 6040605 | 5242 | 0.024 | -0.0433 | No | ||
41 | PLCB1 | 2570050 7100102 | 5484 | 0.021 | -0.0557 | No | ||
42 | ANXA10 | 4050750 | 5666 | 0.019 | -0.0650 | No | ||
43 | SLITRK3 | 5910041 | 5731 | 0.019 | -0.0680 | No | ||
44 | HOXC4 | 1940193 | 5751 | 0.018 | -0.0685 | No | ||
45 | CHCHD7 | 6620692 | 5873 | 0.017 | -0.0746 | No | ||
46 | MYF6 | 2690576 | 5913 | 0.017 | -0.0762 | No | ||
47 | CLOCK | 1410070 2940292 3390075 | 5935 | 0.017 | -0.0769 | No | ||
48 | PPARGC1A | 4670040 | 5938 | 0.017 | -0.0766 | No | ||
49 | MAN1C1 | 730133 870398 2340044 | 6087 | 0.015 | -0.0842 | No | ||
50 | GAD2 | 1400088 | 6372 | 0.013 | -0.0992 | No | ||
51 | HOXB8 | 3710450 | 6441 | 0.013 | -0.1025 | No | ||
52 | PRRX1 | 4120193 4480390 | 6452 | 0.013 | -0.1027 | No | ||
53 | HOXC10 | 5360170 | 6580 | 0.012 | -0.1093 | No | ||
54 | USF2 | 3870368 5570348 6940039 | 6621 | 0.012 | -0.1111 | No | ||
55 | LMO1 | 3170528 | 6765 | 0.011 | -0.1186 | No | ||
56 | FGFR2 | 4670601 5570402 6940377 | 6899 | 0.010 | -0.1255 | No | ||
57 | NHLH2 | 6200021 | 6946 | 0.010 | -0.1277 | No | ||
58 | PURA | 3870156 | 7035 | 0.010 | -0.1322 | No | ||
59 | ODZ1 | 5050731 | 7113 | 0.009 | -0.1361 | No | ||
60 | PTPN22 | 1690647 7100239 | 7187 | 0.009 | -0.1398 | No | ||
61 | PHOX2B | 5270075 | 7225 | 0.009 | -0.1416 | No | ||
62 | SLC26A7 | 1850398 3830377 | 7313 | 0.008 | -0.1461 | No | ||
63 | EYA1 | 1450278 5220390 | 7336 | 0.008 | -0.1471 | No | ||
64 | ESRRG | 4010181 | 7440 | 0.008 | -0.1524 | No | ||
65 | SOX18 | 2320086 | 7491 | 0.008 | -0.1549 | No | ||
66 | ELP4 | 1230576 | 7809 | 0.006 | -0.1719 | No | ||
67 | SATB2 | 2470181 | 7962 | 0.006 | -0.1800 | No | ||
68 | IRX4 | 1980102 | 8269 | 0.005 | -0.1965 | No | ||
69 | NPR3 | 1580239 | 8419 | 0.004 | -0.2044 | No | ||
70 | RAB3C | 5420072 | 8431 | 0.004 | -0.2049 | No | ||
71 | NEUROG1 | 380341 | 8583 | 0.004 | -0.2130 | No | ||
72 | MYT1 | 6770524 | 8692 | 0.003 | -0.2187 | No | ||
73 | LGI1 | 1850020 | 8832 | 0.003 | -0.2262 | No | ||
74 | ZFPM2 | 460072 | 9005 | 0.002 | -0.2355 | No | ||
75 | SDPR | 3360292 | 9186 | 0.002 | -0.2452 | No | ||
76 | ELF4 | 4850193 | 9326 | 0.001 | -0.2527 | No | ||
77 | FGF7 | 5390484 | 9370 | 0.001 | -0.2550 | No | ||
78 | GNAT2 | 2450433 | 9412 | 0.001 | -0.2572 | No | ||
79 | LRRTM1 | 1690324 | 9435 | 0.001 | -0.2583 | No | ||
80 | BAI3 | 940692 | 9500 | 0.001 | -0.2618 | No | ||
81 | LHX6 | 2360731 3360397 | 9697 | -0.000 | -0.2724 | No | ||
82 | HOXD8 | 3710156 | 9722 | -0.000 | -0.2737 | No | ||
83 | C1QTNF7 | 2970619 | 9734 | -0.000 | -0.2743 | No | ||
84 | CDKL5 | 2450070 | 10136 | -0.001 | -0.2960 | No | ||
85 | FGF12 | 1740446 2360037 | 10144 | -0.001 | -0.2963 | No | ||
86 | HSD17B2 | 3800541 | 10220 | -0.002 | -0.3004 | No | ||
87 | BOC | 5270348 | 10255 | -0.002 | -0.3022 | No | ||
88 | P518 | 3610435 | 10461 | -0.002 | -0.3132 | No | ||
89 | ARX | 6900504 | 10554 | -0.003 | -0.3181 | No | ||
90 | ACMSD | 1450538 | 10649 | -0.003 | -0.3231 | No | ||
91 | HSN2 | 610180 | 10691 | -0.003 | -0.3253 | No | ||
92 | GABRB2 | 870059 | 10764 | -0.003 | -0.3291 | No | ||
93 | WNT7A | 1170315 | 10769 | -0.003 | -0.3292 | No | ||
94 | KCNIP2 | 60088 1780324 | 10844 | -0.004 | -0.3331 | No | ||
95 | PTPRD | 520008 3120097 | 10876 | -0.004 | -0.3347 | No | ||
96 | HOXA11 | 6980133 | 11187 | -0.005 | -0.3514 | No | ||
97 | MLSTD1 | 3710184 | 11209 | -0.005 | -0.3524 | No | ||
98 | NR4A3 | 2900021 5860095 5910039 | 11354 | -0.005 | -0.3600 | No | ||
99 | SLC6A15 | 5290176 6040017 | 11555 | -0.006 | -0.3707 | No | ||
100 | CREB5 | 2320368 | 11672 | -0.006 | -0.3768 | No | ||
101 | COL11A2 | 5130341 | 11700 | -0.007 | -0.3781 | No | ||
102 | TBX5 | 2900132 6370484 | 11744 | -0.007 | -0.3802 | No | ||
103 | KCNJ16 | 4780273 | 11750 | -0.007 | -0.3803 | No | ||
104 | NEUROD2 | 5290097 | 11795 | -0.007 | -0.3825 | No | ||
105 | RARB | 430139 1410138 | 12049 | -0.008 | -0.3960 | No | ||
106 | GK2 | 6510736 | 12171 | -0.009 | -0.4023 | No | ||
107 | CGA | 630403 | 12431 | -0.010 | -0.4161 | No | ||
108 | NEUROD6 | 4670731 | 12492 | -0.010 | -0.4191 | No | ||
109 | FUT11 | 6040692 | 12546 | -0.011 | -0.4216 | No | ||
110 | KLF15 | 4230164 | 12771 | -0.012 | -0.4334 | No | ||
111 | DMP1 | 4760398 | 12790 | -0.012 | -0.4341 | No | ||
112 | TCL1A | 3420367 | 12860 | -0.013 | -0.4375 | No | ||
113 | SV2A | 1450039 5570685 | 12866 | -0.013 | -0.4374 | No | ||
114 | RIMS2 | 670725 | 13108 | -0.014 | -0.4501 | No | ||
115 | ALDH1A2 | 2320301 | 13576 | -0.019 | -0.4749 | No | ||
116 | SLC6A4 | 2230372 | 13655 | -0.020 | -0.4785 | No | ||
117 | ITGA7 | 1230739 | 13958 | -0.024 | -0.4942 | No | ||
118 | PLCD4 | 6450040 | 14008 | -0.025 | -0.4962 | No | ||
119 | PRDM13 | 1430022 | 14065 | -0.026 | -0.4985 | No | ||
120 | POU3F4 | 870274 | 14290 | -0.031 | -0.5098 | No | ||
121 | SOX5 | 2370576 2900167 3190128 5050528 | 14297 | -0.031 | -0.5093 | No | ||
122 | PCSK2 | 360017 430528 5900619 | 14369 | -0.032 | -0.5123 | No | ||
123 | APOBEC2 | 1690520 | 14394 | -0.033 | -0.5127 | No | ||
124 | AP3M2 | 6370474 | 14556 | -0.037 | -0.5204 | No | ||
125 | RHOBTB3 | 4010687 | 14925 | -0.051 | -0.5389 | No | ||
126 | MDGA1 | 1170139 | 15050 | -0.057 | -0.5441 | No | ||
127 | FHL1 | 60278 | 15297 | -0.073 | -0.5554 | No | ||
128 | MYO10 | 3830576 5570092 | 15344 | -0.076 | -0.5558 | No | ||
129 | ZIC4 | 1500082 | 15644 | -0.104 | -0.5692 | No | ||
130 | SLC12A6 | 610278 1980035 5340671 | 15685 | -0.108 | -0.5684 | No | ||
131 | RAB5B | 130397 1980273 6900731 | 16133 | -0.168 | -0.5881 | No | ||
132 | KLHL5 | 3060484 6400292 | 16186 | -0.175 | -0.5861 | No | ||
133 | PPP3CB | 6020156 | 16598 | -0.248 | -0.6016 | Yes | ||
134 | FOXP3 | 940707 1850692 | 16687 | -0.262 | -0.5992 | Yes | ||
135 | FLI1 | 3990142 | 16746 | -0.273 | -0.5949 | Yes | ||
136 | LARGE | 6940068 | 16862 | -0.304 | -0.5929 | Yes | ||
137 | KCNN3 | 6520600 6420138 | 16898 | -0.313 | -0.5862 | Yes | ||
138 | CHD2 | 4070039 | 16974 | -0.332 | -0.5812 | Yes | ||
139 | MARCKS | 7040450 | 16986 | -0.336 | -0.5727 | Yes | ||
140 | SLC20A1 | 6420014 | 17083 | -0.367 | -0.5679 | Yes | ||
141 | NDUFA4 | 6860364 | 17112 | -0.377 | -0.5591 | Yes | ||
142 | RPA3 | 5700136 | 17431 | -0.515 | -0.5623 | Yes | ||
143 | TRIM8 | 6130441 | 17475 | -0.533 | -0.5501 | Yes | ||
144 | HNRPA0 | 2680048 | 17550 | -0.569 | -0.5386 | Yes | ||
145 | GATA3 | 6130068 | 17582 | -0.581 | -0.5244 | Yes | ||
146 | ARID5A | 2450133 | 17697 | -0.643 | -0.5131 | Yes | ||
147 | HOXA7 | 5910152 | 17729 | -0.661 | -0.4967 | Yes | ||
148 | SOX4 | 2260091 | 17765 | -0.693 | -0.4797 | Yes | ||
149 | TOB1 | 4150138 | 17791 | -0.710 | -0.4617 | Yes | ||
150 | CLK2 | 510079 2630736 | 17817 | -0.730 | -0.4432 | Yes | ||
151 | SH3BGRL3 | 1850750 | 18299 | -1.376 | -0.4317 | Yes | ||
152 | HSD11B1 | 450066 5550408 | 18314 | -1.402 | -0.3942 | Yes | ||
153 | ZFP36L1 | 2510138 4120048 | 18471 | -2.052 | -0.3467 | Yes | ||
154 | ETS2 | 360451 | 18475 | -2.094 | -0.2898 | Yes | ||
155 | DUSP6 | 5910286 7100070 | 18498 | -2.291 | -0.2285 | Yes | ||
156 | CCND2 | 5340167 | 18548 | -2.713 | -0.1572 | Yes | ||
157 | TLE4 | 1450064 1500519 | 18549 | -2.720 | -0.0831 | Yes | ||
158 | BCL6 | 940100 | 18581 | -3.177 | 0.0019 | Yes |